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Journal Articles

EP300 Suppresses Leukemia Development in Myelodysplastic Syndrome through Myb Repression

Na Man, Gloria Mas Martin, PhD, Daniel Karl, PhD, Jun Sun, PhD, Fan Liu, PhD, Miguel Torres-Martin, PhD, Hidehiro Itonaga, MD PhD, Concepcion Martinez, B.S., Shi Chen, Stephanie Duffort, Pierre-Jacques Hamard, PhD, Ye Xu, PhD, Luisa Cimmino, PhDBSc, Feng-Chun Yang, MD PhD, Philip A. Cole, MD PhD, Mingjiang Xu, MD PhD, Maria E. Figueroa, MD, Stephen Nimer, MD

Blood (2019) 134 (Supplement_1): 561.

https://doi.org/10.1182/blood-2019-130507

Published: 2019

Journal Articles

Cooperative Epigenetic Regulation By ASXL1 and NF1 Loss on Leukemogenesis

Peng Zhang, PhD, Fuhong He, PhD, Jie Bai, MD, Shi Chen, Stephen D. Nimer, MD, Yuan Zhou, PhD, Mingjiang Xu, MD PhD, Qianfei Wang, PhD, Feng-Chun Yang, MD PhD

Blood (2018) 132 (Supplement 1): 652.

https://doi.org/10.1182/blood-2018-99-110964

Published: 2018

Journal Articles

Hoxblinc Is Aberrantly Expressed in Acute Myeloid Leukemia and Functions As a Potent Oncogenic Long Non-Coding RNA in Leukemogenesis

Ganqian Zhu, PhD, Huacheng Luo, Shi Chen, Qian Lai, Ying Guo, Olga A Guryanova, MDPhD, Yi Qiu, Feng-Chun Yang, MD PhD, Wei Li, Stephen D. Nimer, MD, Suming Huang, Mingjiang Xu, MD PhD

Blood (2018) 132 (Supplement 1): 886.

https://doi.org/10.1182/blood-2018-99-112232

Published: 2018

Journal Articles

Modulation of TET2 Activity By Ascorbic Acid and Factors Affecting Lysine Acetylation

Blood (2018) 132 (Supplement 1): 4346.

https://doi.org/10.1182/blood-2018-99-119712

Published: 2018

Journal Articles

Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies

Blood (2018) 131 (3): 328–341.

https://doi.org/10.1182/blood-2017-06-789669

Published: 2018

Includes: Supplemental data

Journal Articles

Disruption of CTCF Boundary Remodels Chromatin Domain and Reprograms HOX Gene Transcription in Acute Myeloid Leukemia

Huacheng Luo, PhD, Fei Wang, MDPhD, Haoli Li, PhD, Qinghua Du, MD, Bowen Yan, Ph. D, Shi Chen, Baoan Chen, MDPhD, Yi Qiu, PhD, Mingjiang Xu, MDPhD, Suming Huang, PhD

Blood (2017) 130 (Supplement 1): 244.

https://doi.org/10.1182/blood.V130.Suppl_1.244.244

Published: 2017

Journal Articles

Modulation of TET2 Activity with Ascorbic Acid in Myeloid Neoplasia: Diagnostic and Therapeutic Implications

Edward F Greenberg, MD, Cassandra M. Hirsch, BS, Shi Chen, Xiaochen Liiu, Babal K Jha, PhD, Valeria Visconte, PhD, Dewen You, PhD, Bartlomiej P. Przychodzen, MSc, Thomas Laframboise, PhD, Hideki Makishima, MD PhD, Aziz Nazha, MD, Mingjiang Xu, MDPhD, Daniel Gackowski, PhD, Mridul Mukherji, D.Phil., Mikkael A. Sekeres, MD MS, Ryszard Ólinski, Professor, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 1205.

https://doi.org/10.1182/blood.V130.Suppl_1.1205.1205

Published: 2017

Journal Articles

ASXL2 Is Required for Normal Hematopoiesis and Loss of a sxl2 Leads to Myeloid Malignancies in Mice

Jianping Li, Fuhong He, PhD, Peng Zhang, PhD, Shi Chen, MD PhD, Hui Shi, Yanling Sun, Guo Ying, Hui Yang, Stephen D. Nimer, MD, Qian-Fei Wang, Mingjiang Xu, MD PhD, Feng-Chun Yang, MD PhD

Blood (2016) 128 (22): 1509.

https://doi.org/10.1182/blood.V128.22.1509.1509

Published: 2016

Journal Articles

Cooperative Effect of Haploinsufficient ASXL1 and NF1 in Acute Myeloid Leukemia Transformation

Peng Zhang, PhD, Shohei Yamamoto, MD PhD, Shi Chen, MD PhD, Yuan Zhou, PhD, Mingjiang Xu, MD PhD, Feng-Chun Yang, MD PhD

Blood (2015) 126 (23): 1224.

https://doi.org/10.1182/blood.V126.23.1224.1224

Published: 2015

Journal Articles

Combined Loss of Tet1 and Tet2 Promotes B-Cell, but Not Myeloid Malignancies in Mice

Zhigang Zhao, MDPhD, Lin Li, PhD, Meelad Dawlaty, PhD, Feng Pan, PhD, Zhe Li, PhD, Yuan Zhou, PhD, Hui Shi, MD PhD, Shi Chen, MD PhD, Ophelia Weeks, PhD, Weiping Yuan, PhD, Hongyu Ni, PhD, Feng-Chun Yang, MD PhD, Rudolph Jaenisch, PhD, Peng Jin, MDPhD, Mingjiang Xu, MDPhD

Blood (2015) 126 (23): 3650.

https://doi.org/10.1182/blood.V126.23.3650.3650

Published: 2015

Journal Articles

ASXL1 Is a Key Regulator for Erythroid Development and Asxl1 Loss Impairs Erythropoiesis In Vivo

Shohei Yamamoto, MD PhD, Hui Shi, MD PhD, Shi Chen, MD PhD, Peng Zhang, PhD, Yuan Zhou, PhD, Mingjiang Xu, MD PhD, Feng-Chun Yang, MD PhD

Blood (2015) 126 (23): 3644.

https://doi.org/10.1182/blood.V126.23.3644.3644

Published: 2015

Journal Articles

Loss of Asxl1 leads to myelodysplastic syndrome–like disease in mice

Jiapeng Wang, Zhaomin Li, Yongzheng He, Feng Pan, Shi Chen, Steven Rhodes, Lihn Nguyen, Jin Yuan, Li Jiang, Xianlin Yang, Ophelia Weeks, Ziyue Liu, Jiehao Zhou, Hongyu Ni, Chen-Leng Cai, Mingjiang Xu, Feng-Chun Yang

Blood (2014) 123 (4): 541–553.

https://doi.org/10.1182/blood-2013-05-500272

Published: 2014

Includes: Supplemental data

Journal Articles

Haploinsufficiency of Nf1 in Myeloid Lineages Contributes to Neurofibromatosis Type 1 Associated Skeletal Deficits

Steven D. Rhodes, Yongzheng He, M.D., Shi Chen, Hao Yang, Keshav M. Menon, Karl Staser, Ph.D., Xianlin Yang, Khalid S. Mohammad, M.D. Ph.D., Theresa Guise, M.D., Mingjiang Xu, M.D., Ph.D., Feng-chun Yang, M.D., Ph.D.

Blood (2012) 120 (21): 830.

https://doi.org/10.1182/blood.V120.21.830.830

Published: 2012

Journal Articles

Normal Hematopoiesis and Neurofibromin -Deficient Myeloproliferative Disease Require Erk

Karl Staser, PhD, Yi Zeng, MD, PhD, Su-jung Park, PhD, Steven D. Rhodes, Yongzheng He, M.D., Matthew A. Shew, Jeff Gehlhausen, Donna Cerabona, Shi Chen, Zejin Sun, MD, PhD, Grzegorz Nalepa, MD, PhD, Feng-chun Yang, M.D., Ph.D., D. Wade Clapp, MD

Blood (2012) 120 (21): 704.

https://doi.org/10.1182/blood.V120.21.704.704

Published: 2012

Journal Articles

PAK1 Regulates Eotaxin-Mediated Murine Eosinophil Migration in Vitro and In Vivo

Muithi Mwanthi, Gracie Michels, Karl Staser, PhD, Sarita Sehra, PhD, Michal Jander, Shi Chen, PhD, David S Wilkes, MD, Mark Kaplan, PhD, Su-jung Park, PhD, D. Wade Clapp, MD

Blood (2011) 118 (21): 18.

https://doi.org/10.1182/blood.V118.21.18.18

Published: 2011

Journal Articles

Erk1 Plays Critical Role in Macrophage Development

Yongzheng He, MD, Karl Staser, PhD, Steven D Rhodes, Xiaohua Wu, Ping Zhang, Shi Chen, Feng-chun Yang, MD, PhD

Blood (2011) 118 (21): 517.

https://doi.org/10.1182/blood.V118.21.517.517

Published: 2011

Journal Articles

Impaired Bone Marrow Microenvironment in Fanconi Anemia Murine Model Is Responsible for the Defective Hematopoietic Stem/ Progenitor Cell Mobilization.

Yan Li, PhD, MD, Shi Chen, MD, PhD, Yongzheng He, MD, Xiaohong Li, Fengchun Yang, MD, PhD

Blood (2009) 114 (22): 3629.

https://doi.org/10.1182/blood.V114.22.3629.3629

Published: 2009

Journal Articles

p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics

Jayme D. Allen, Zahara M. Jaffer, Su-Jung Park, Sarah Burgin, Clemens Hofmann, Mary Ann Sells, Shi Chen, Ethel Derr-Yellin, Elizabeth G. Michels, Andrew McDaniel, Waylan K. Bessler, David A. Ingram, Simon J. Atkinson, Jeffrey B. Travers, Jonathan Chernoff, D. Wade Clapp

Blood (2009) 113 (12): 2695–2705.

https://doi.org/10.1182/blood-2008-06-160861

Published: 2009

Includes: Supplemental data

Journal Articles

Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg −/− mice in vivo

Yan Li, Shi Chen, Jin Yuan, Yanzhu Yang, Jingling Li, Jin Ma, Xiaohua Wu, Marcel Freund, Karen Pollok, Helmut Hanenberg, W. Scott Goebel, Feng-Chun Yang

Blood (2009) 113 (10): 2342–2351.

https://doi.org/10.1182/blood-2008-07-168138

Published: 2009

Includes: Supplemental data

Journal Articles

Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1 +/− mast cells

Andrew S. McDaniel, Jayme D. Allen, Su-Jung Park, Zahara M Jaffer, Elizabeth G. Michels, Sarah J. Burgin, Shi Chen, Waylan K. Bessler, Clemens Hofmann, David A. Ingram, Jonathan Chernoff, D. Wade Clapp

Blood (2008) 112 (12): 4646–4654.

https://doi.org/10.1182/blood-2008-04-155085

Published: 2008

NARROW

EP300 Suppresses Leukemia Development in Myelodysplastic Syndrome through Myb Repression

Cooperative Epigenetic Regulation By ASXL1 and NF1 Loss on Leukemogenesis

Hoxblinc Is Aberrantly Expressed in Acute Myeloid Leukemia and Functions As a Potent Oncogenic Long Non-Coding RNA in Leukemogenesis

Modulation of TET2 Activity By Ascorbic Acid and Factors Affecting Lysine Acetylation

Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies

Disruption of CTCF Boundary Remodels Chromatin Domain and Reprograms HOX Gene Transcription in Acute Myeloid Leukemia

Modulation of TET2 Activity with Ascorbic Acid in Myeloid Neoplasia: Diagnostic and Therapeutic Implications

ASXL2 Is Required for Normal Hematopoiesis and Loss of a sxl2 Leads to Myeloid Malignancies in Mice

Cooperative Effect of Haploinsufficient ASXL1 and NF1 in Acute Myeloid Leukemia Transformation

Combined Loss of Tet1 and Tet2 Promotes B-Cell, but Not Myeloid Malignancies in Mice

ASXL1 Is a Key Regulator for Erythroid Development and Asxl1 Loss Impairs Erythropoiesis In Vivo

Loss of Asxl1 leads to myelodysplastic syndrome–like disease in mice

Haploinsufficiency of Nf1 in Myeloid Lineages Contributes to Neurofibromatosis Type 1 Associated Skeletal Deficits

Normal Hematopoiesis and Neurofibromin -Deficient Myeloproliferative Disease Require Erk

PAK1 Regulates Eotaxin-Mediated Murine Eosinophil Migration in Vitro and In Vivo

Erk1 Plays Critical Role in Macrophage Development

Impaired Bone Marrow Microenvironment in Fanconi Anemia Murine Model Is Responsible for the Defective Hematopoietic Stem/ Progenitor Cell Mobilization.

p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics

Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg −/− mice in vivo

Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1 +/− mast cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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