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Journal Articles

Targeting Enterobacter cloacae attenuates osteolysis by reducing ammonium in multiple myeloma

Available to Purchase
Qin Yang, Yinghong Zhu, Xingxing Jian, Yi Qiu, Yan Zhu, Lia Zhao, Yanjuan He, Gang An, Lugui Qiu, Jiaojiao Guo, Nihan He, Huerxidan Abudumijiti, Cong Hu, Xun Chen, Siqing Huang, Xiangling Feng, Xin Li, Jing Liu, Yajing Xu, Wen Zhou
Journal: Blood
Blood (2025) 145 (17): 1876–1889.
https://doi.org/10.1182/blood.2024025694
Published: 2025
Includes: Supplemental data
Journal Articles

HoxBlinc LncRNA Reprograms CTCF Independent TADs to Drive Leukemic Transcription and HSC Dysregulation in NUP98 Fusion Transformed Leukemia

Free
Karina Hamamoto, Ganqian Zhu, Julia Lesperance, Huacheng Luo, Ying D Li, Nupur Nigam, Arati Sharma, Feng-Chun Yang, David F. Claxton, Yi Qiu, Peter D. Aplan, Mingjiang Xu, Suming Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4108.
https://doi.org/10.1182/blood-2024-199171
Published: 2024
Journal Articles

Ncrna-a3 Epigenetically Regulates TAL1 and Its Target Genes to Drive Erythroid Differentiation

Free
Meghana Matur, Yasin Uzun, Yi Qiu, Suming Huang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1077.
https://doi.org/10.1182/blood-2023-188112
Published: 2023
Journal Articles

Myeloid Master Regulators PU.1 and CEBPA Suppress Leukemogenesis through Downregulating Cell Cycle Related Genes in NPM1 Mutated Leukemia

Free
Karina Hamamoto, Julia Lesperance, Huacheng Luo, Zachary Zaroogian, Olga A. Guryanova, Yi Qiu, Suming Huang
Journal: Blood
Blood (2023) 142 (Supplement 1): 5690.
https://doi.org/10.1182/blood-2023-189988
Published: 2023
Journal Articles

GATA-1 and BCL11A Collaboratively Regulate Erythroid Gene Expression through HDAC1 Dependent Manner

Free
Min Young Kim, Suming Huang, Yi Qiu
Journal: Blood
Blood (2023) 142 (Supplement 1): 2456.
https://doi.org/10.1182/blood-2023-190084
Published: 2023
Journal Articles

NPM1 Mutation Reprograms Leukemic Transcription Network Via Reshaping CTCF-Defined TAD Topology

Free
Karina Hamamoto, Qian Lai, Huacheng Luo, Julia Lesperance, Zachary Zaroogian, Jie Zha, Yi Qiu, Olga A Guryanova, Bing Xu, Suming Huang
Journal: Blood
Blood (2022) 140 (Supplement 1): 722–723.
https://doi.org/10.1182/blood-2022-160367
Published: 2022
Journal Articles

The Role of Hottip Lncrna m 6 a Modification in AML Genome Organization and Leukemogenesis

Free
Huacheng Luo, Karina Hamamoto, Julia Lesperance, Yi Qiu, Suming Huang
Journal: Blood
Blood (2022) 140 (Supplement 1): 730–731.
https://doi.org/10.1182/blood-2022-157781
Published: 2022
Journal Articles

Long noncoding RNAs: emerging regulators of normal and malignant hematopoiesis

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Yi Qiu, Mingjiang Xu, Suming Huang
Journal: Blood
Blood (2021) 138 (23): 2327–2336.
https://doi.org/10.1182/blood.2021011992
Published: 2021
Journal Articles

Hottip -Mediated R-Loops Regulate CTCF TAD Boundary to Control WNT/b-Catenin Pathway in AML Genome

Free
Huacheng Luo, PhD, Ganqian Zhu, PhD, Xiaoyan Ma, MD PhD, David F. Claxton, MD, Yi Qiu, PhD, Mingjiang Xu, MDPhD, Suming Huang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44–45.
https://doi.org/10.1182/blood-2020-137816
Published: 2020
Journal Articles

Residual TP53 Mutation Contributes to Chemoresistance through Clonal Expansion in Acute Myeloid Leukemia

Free
Bowen Yan, PhD, Qinwei Chen, MS, Jianfeng Xu, PhD, Wei Li, PhD, Bing Xu, Suming Huang, PhD, Yi Qiu, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2731.
https://doi.org/10.1182/blood-2019-127511
Published: 2019
Journal Articles

HOXA11 Regulates Chemoresistance By Modulating p53 Gene Expression in Acute Myeloid Leukemia

Free
Xutao Guo, MD, Bowen Yan, PhD, Yi Qiu, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5182.
https://doi.org/10.1182/blood-2019-127542
Published: 2019
Journal Articles

Hottip Lncrna Reinforces CTCF Defined Chromatin Boundaries and Drives Wnt Target Gene Expression in AML Leukemogenesis

Free
Huacheng Luo, Ganqian Zhu, PhD, Tsz Kan Fung, Yi Qiu, PhD, Mingjiang Xu, MD PhD, Chi Wai Eric So, Suming Huang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 277.
https://doi.org/10.1182/blood-2019-127323
Published: 2019
Journal Articles

Low-Dose Triptolide Enhances Bromodomain Inhibitor JQ1-Induced Apoptosis of Acute Myeloid Leukemia Cells Via Down-Regulation of c-Myc Following RAS/MEK/ERK Inhibition

Free
Bing Xu, Yuanfei Shi, Haijun Zhao, Yi Qiu, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5757.
https://doi.org/10.1182/blood-2019-123740
Published: 2019
Journal Articles

Activation of Hottip lncrna Perturbs HSC Function Leading to AML like Disease in Mice

Free
Huacheng Luo, Ganqian Zhu, PhD, Jie Zha, MD, Bowen Yan, Ph. D, Ying Guo, Jianfeng Xu, PhD, Qian Lai, Bing Xu, MD PhD, Feng-Chun Yang, MD PhD, Wei Li, Yi Qiu, Mingjiang Xu, MD PhD, Suming Huang
Journal: Blood
Blood (2018) 132 (Supplement 1): 3877.
https://doi.org/10.1182/blood-2018-99-110218
Published: 2018
Journal Articles

Hoxblinc Is Aberrantly Expressed in Acute Myeloid Leukemia and Functions As a Potent Oncogenic Long Non-Coding RNA in Leukemogenesis

Free
Ganqian Zhu, PhD, Huacheng Luo, Shi Chen, Qian Lai, Ying Guo, Olga A Guryanova, MDPhD, Yi Qiu, Feng-Chun Yang, MD PhD, Wei Li, Stephen D. Nimer, MD, Suming Huang, Mingjiang Xu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 886.
https://doi.org/10.1182/blood-2018-99-112232
Published: 2018
Journal Articles

CTCF boundary remodels chromatin domain and drives aberrant HOX gene transcription in acute myeloid leukemia

Free
Huacheng Luo, Fei Wang, Jie Zha, Haoli Li, Bowen Yan, Qinghua Du, Fengchun Yang, Amin Sobh, Christopher Vulpe, Leylah Drusbosky, Christopher Cogle, Iouri Chepelev, Bing Xu, Stephen D. Nimer, Jonathan Licht, Yi Qiu, Baoan Chen, Mingjiang Xu, Suming Huang
Journal: Blood
Blood (2018) 132 (8): 837–848.
https://doi.org/10.1182/blood-2017-11-814319
Published: 2018
Includes: Supplemental data
Journal Articles

Epigenetic Drugs Selectively Target a Population of AML Cells Which Are Positive for CD123 Cell Surface Marker and Are Chemoresistant

Free
Bowen Yan, Ph. D, Suming Huang, PhD, Yi Qiu, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3929.
https://doi.org/10.1182/blood.V130.Suppl_1.3929.3929
Published: 2017
Journal Articles

Disregulation of CTCF Boundary at the HOX Locus Enhances Sensitity to Multiple Drug Treatment in Myeloid Malignancies

Free
Jie Zha, MD, Huacheng Luo, PhD, Yi Qiu, PhD, Suming Huang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3816.
https://doi.org/10.1182/blood.V130.Suppl_1.3816.3816
Published: 2017
Journal Articles

GATA-1 Deacetylation and Interaction with HDAC1 Is Critical for GATA-1 Mediated Gene Transcription

Free
Bowen Yan, Ph. D, Suming Huang, PhD, Yi Qiu, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 945.
https://doi.org/10.1182/blood.V130.Suppl_1.945.945
Published: 2017
Journal Articles

Disruption of CTCF Boundary Remodels Chromatin Domain and Reprograms HOX Gene Transcription in Acute Myeloid Leukemia

Free
Huacheng Luo, PhD, Fei Wang, MDPhD, Haoli Li, PhD, Qinghua Du, MD, Bowen Yan, Ph. D, Shi Chen, Baoan Chen, MDPhD, Yi Qiu, PhD, Mingjiang Xu, MDPhD, Suming Huang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 244.
https://doi.org/10.1182/blood.V130.Suppl_1.244.244
Published: 2017