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Journal Articles

HoxBlinc LncRNA Reprograms CTCF Independent TADs to Drive Leukemic Transcription and HSC Dysregulation in NUP98 Fusion Transformed Leukemia

Karina Hamamoto, Ganqian Zhu, Julia Lesperance, Huacheng Luo, Ying D Li, Nupur Nigam, Arati Sharma, Feng-Chun Yang, David F. Claxton, Yi Qiu, Peter D. Aplan, Mingjiang Xu, Suming Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4108.
https://doi.org/10.1182/blood-2024-199171
Published: 2024
Journal Articles

Hottip -Mediated R-Loops Regulate CTCF TAD Boundary to Control WNT/b-Catenin Pathway in AML Genome

Huacheng Luo, PhD, Ganqian Zhu, PhD, Xiaoyan Ma, MD PhD, David F. Claxton, MD, Yi Qiu, PhD, Mingjiang Xu, MDPhD, Suming Huang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44–45.
https://doi.org/10.1182/blood-2020-137816
Published: 2020
Journal Articles

Hottip Lncrna Reinforces CTCF Defined Chromatin Boundaries and Drives Wnt Target Gene Expression in AML Leukemogenesis

Huacheng Luo, Ganqian Zhu, PhD, Tsz Kan Fung, Yi Qiu, PhD, Mingjiang Xu, MD PhD, Chi Wai Eric So, Suming Huang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 277.
https://doi.org/10.1182/blood-2019-127323
Published: 2019
Journal Articles

Activation of Hottip lncrna Perturbs HSC Function Leading to AML like Disease in Mice

Huacheng Luo, Ganqian Zhu, PhD, Jie Zha, MD, Bowen Yan, Ph. D, Ying Guo, Jianfeng Xu, PhD, Qian Lai, Bing Xu, MD PhD, Feng-Chun Yang, MD PhD, Wei Li, Yi Qiu, Mingjiang Xu, MD PhD, Suming Huang
Journal: Blood
Blood (2018) 132 (Supplement 1): 3877.
https://doi.org/10.1182/blood-2018-99-110218
Published: 2018
Journal Articles

Hoxblinc Is Aberrantly Expressed in Acute Myeloid Leukemia and Functions As a Potent Oncogenic Long Non-Coding RNA in Leukemogenesis

Ganqian Zhu, PhD, Huacheng Luo, Shi Chen, Qian Lai, Ying Guo, Olga A Guryanova, MDPhD, Yi Qiu, Feng-Chun Yang, MD PhD, Wei Li, Stephen D. Nimer, MD, Suming Huang, Mingjiang Xu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 886.
https://doi.org/10.1182/blood-2018-99-112232
Published: 2018