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Journal Articles

Tyrosine Phosphorylation of CARM1 Promotes Its Enzymatic Activity and Alters Its Target Specificity in Myeloid Neoplasms with Hyperactivated JAK2

Hidehiro Itonaga, Adnan K Mookhtiar, Sarah Greenblatt, Fan Liu, Concepcion Martinez, Renata Grozovsky, Daniel Bilbao, Masai Rains, Pierre-Jacques Hamard, Jun Sun, Afoma Umeano, Stephanie Duffort, Chuan Chen, Na Man, Gloria Mas Martin, Stephen Schürer, Stephen D Nimer
Journal: Blood
Blood (2022) 140 (Supplement 1): 3021–3022.
https://doi.org/10.1182/blood-2022-156887
Published: 2022
Journal Articles

The NLRC4 Inflammasome Drives Myelodysplastic Syndrome By Linking Epigenetic Reprogramming and Innate Immune Signaling

Chuan Chen, Na Man, Francesco Tamiro, Krystal Hossack, Julio Poveda, Daniel Bilbao, Gloria Mas, Stephanie Duffort, Concepcion Martinez, Hidehiro Itonaga, Fan Liu, Jennifer R Chapman-Fredricks, Stephen D Nimer
Journal: Blood
Blood (2022) 140 (Supplement 1): 3009–3010.
https://doi.org/10.1182/blood-2022-160075
Published: 2022
Journal Articles

The Baf Subunit Dpf2 Regulates Resolution of Inflammation By Controlling Macrophage Differentiation Transcription Factor Networks

Gloria Mas Martin, PhD, Na Man, Daniel Karl, PhD, Concepcion Martinez, B.S., Stephanie Duffort, Hidehiro Itonaga, MD PhD, Adnan K Mookhtiar, BS, Daniel Bilbao, PhD, Kranthi Kunkalla, Alfredo M Valencia, Clayton Collings, Cigall Kadoch, PhD, Francisco Vega, MDPhD, Scott C. Kogan, MD, Stephen Nimer, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13.
https://doi.org/10.1182/blood-2020-142030
Published: 2020
Journal Articles

EP300 Suppresses Leukemia Development in Myelodysplastic Syndrome through Myb Repression

Na Man, Gloria Mas Martin, PhD, Daniel Karl, PhD, Jun Sun, PhD, Fan Liu, PhD, Miguel Torres-Martin, PhD, Hidehiro Itonaga, MD PhD, Concepcion Martinez, B.S., Shi Chen, Stephanie Duffort, Pierre-Jacques Hamard, PhD, Ye Xu, PhD, Luisa Cimmino, PhDBSc, Feng-Chun Yang, MD PhD, Philip A. Cole, MD PhD, Mingjiang Xu, MD PhD, Maria E. Figueroa, MD, Stephen Nimer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 561.
https://doi.org/10.1182/blood-2019-130507
Published: 2019
Journal Articles

The Three E Proteins Define a Heterogeneity of the AML1-ETO-Containing Transcription Factor Complex (AETFC) and Differentially Regulate t(8;21) Leukemogenesis

Na Liu, Junhong Song, Yangyang Xie, Xiao-Lin Wang, Bowen Rong, Na Man, PhD, Meng-Meng Zhang, Qunling Zhang, MD PhD, Fei-Fei Gao, Mei-Rong Du, Ying Zhang, Jian Shen, Chun-Hui Xu, Cheng-Long Hu, Ji-Chuan Wu, Ping Liu, Yuan-Liang Zhang, Yin-Yin Xie, Ping Liu, Jinyan Huang, PhD, Qiu-Hua Huang, Fei Lan, Shuhong Shen, MD PhD, Stephen D. Nimer, MD, Zhu Chen, Sai-Juan Chen, Robert G. Roeder, Lan Wang, MD, Xiao-Jian Sun, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5247.
https://doi.org/10.1182/blood-2018-99-112372
Published: 2018
Journal Articles

CARM1 Inhibition: Evaluation of Response and Efficacy in Acute Myeloid Leukemia

Adnan K Mookhtiar, BS, Sarah Greenblatt, PhD, Na Man, PhD, Daniel Karl, PhD, Vasileios Stathias, PhD, Stephan Schurer, PhD, Stephen D. Nimer, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2719.
https://doi.org/10.1182/blood-2018-99-114981
Published: 2018
Journal Articles

CARM1/PRMT4 As a Novel Therapeutic Target for AML

Sarah Greenblatt, PhD, Na Man, Pierre-Jacques Hamard, PhD, Concepcion Martinez, B.S., Ye Xu, PhD, Fan Liu, PhD, Justin M Watts, MD, Daniel G. Tenen, MD, Stephen D. Nimer, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 241.
https://doi.org/10.1182/blood.V130.Suppl_1.241.241
Published: 2017
Journal Articles

Caspase-3 controls AML1-ETO–driven leukemogenesis via autophagy modulation in a ULK1-dependent manner

Na Man, Yurong Tan, Xiao-Jian Sun, Fan Liu, Guoyan Cheng, Sarah M. Greenblatt, Camilo Martinez, Daniel L. Karl, Koji Ando, Ming Sun, Dan Hou, Bingyi Chen, Mingjiang Xu, Feng-Chun Yang, Zhu Chen, Saijuan Chen, Stephen D. Nimer, Lan Wang
Journal: Blood
Blood (2017) 129 (20): 2782–2792.
https://doi.org/10.1182/blood-2016-10-745034
Published: 2017
Includes: Supplemental data
Journal Articles

TAFII250 Is Critical in AML1-ETO Mediated Leukemogenesis

Ye Xu, PhD, Na Man, PhD, Concepcion Martinez, Camilo Martinez, Felipe Beckedorf, Guoyan Cheng, PhD, Sarah Merin Greenblatt, PhD, Lan Wang, PhD, Ramin Shiekhattar, Stephen D. Nimer, MD
Journal: Blood
Blood (2016) 128 (22): 1520.
https://doi.org/10.1182/blood.V128.22.1520.1520
Published: 2016
Journal Articles

Caspase-3 Can Promote Acute Myeloid Leukemia Development By Regulation of Autophagy

Na Man, PhD, Yurong Tan, PhD, Fan Liu, PhD, Guoyan Cheng, PhD, Sarah Merin Greenblatt, PhD, Camilo Martinez, Xiao-Jian Sun, PhD, Stephen D. Nimer, MD, Lan Wang, PhD
Journal: Blood
Blood (2016) 128 (22): 2714.
https://doi.org/10.1182/blood.V128.22.2714.2714
Published: 2016
Journal Articles

Differential role of Id1 in MLL-AF9–driven leukemia based on cell of origin

Brief Report
Na Man, Xiao-Jian Sun, Yurong Tan, Marta García-Cao, Fan Liu, Guoyan Cheng, Megan Hatlen, Haiming Xu, Ronit Shah, Nolan Chastain, Na Liu, Gang Huang, Yuan Zhou, Mengyao Sheng, Junhong Song, Feng-Chun Yang, Robert Benezra, Stephen D. Nimer, Lan Wang
Journal: Blood
Blood (2016) 127 (19): 2322–2326.
https://doi.org/10.1182/blood-2015-11-677708
Published: 2016
Includes: Supplemental data
Journal Articles

Regulation of AKT signaling by Id1 controls t(8;21) leukemia initiation and progression

Lan Wang, Na Man, Xiao-Jian Sun, Yurong Tan, Marta García-Cao, Fan Liu, Megan Hatlen, Haiming Xu, Gang Huang, Meredith Mattlin, Arpit Mehta, Evadnie Rampersaud, Robert Benezra, Stephen D. Nimer
Journal: Blood
Blood (2015) 126 (5): 640–650.
https://doi.org/10.1182/blood-2015-03-635532
Published: 2015
Includes: Supplemental data