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Journal Articles

Role of Vav1 Genomic Alterations in T-Cell Differentiation and Transformation in Peripheral T-Cell Lymphoma

Jose Rodriguez Cortes, PhD, Anisha R. Cooke, Aidan Quinn, Ioan Filip, PhD, Juan Angel Patino, PhD, Raul Rabadan, PhD, Adolfo A. Ferrando, MD PhD, Teresa Palomero, PhD

Blood (2019) 134 (Supplement_1): 1482.

https://doi.org/10.1182/blood-2019-129438

Published: 2019

Journal Articles

The Histone Demethylase KDM4A Is Required to Sustain H3K9me3/H3K27me3 Epigenetic States and Oncogenesis in MLL-AF9 Acute Myeloid Leukemia

Matthew E Massett, BSc, Niamh Mannion, BSc,PhD, Laura Monaghan, BSc, Joana Bittencourt-Silvestre, BSc, MSc, Sandra Marmiroli, BSc,PhD, Robert M J Liskamp, BSc, PhD, Alison M Michie, BSc, PhD, David Vetrie, BSc, PhD, Xu Huang, BSc, PhD

Blood (2018) 132 (Supplement 1): 3879.

https://doi.org/10.1182/blood-2018-99-111256

Published: 2018

Journal Articles

Mechanism of Synergistic Effects on T Cell Activation By Avadomide (CC-122) and Nivolumab

Yumi Nakayama, PhD, Matthew E. Stokes, PhD, Michelle Waldman, MS, Patrick R. Hagner, PhD, Anita K. Gandhi, PhD

Blood (2018) 132 (Supplement 1): 4133.

https://doi.org/10.1182/blood-2018-99-114469

Published: 2018

Journal Articles

Single-Cell RNA-Seq Reveals AML Cellular Hierarchies Relevant to Clinical Outcomes and Immunity

Peter Van Galen, PhD, Volker Hovestadt, PhD, Marc Wadsworth II, Travis Hughes, Gabriel Kenneth Griffin, MD, Julia A. Verga, Jason Stephansky, Timothy J. Pastika, Jennifer Lombardi Story, Geraldine S. Pinkus, MD, Olga Pozdnyakova, MD PhD, Ilene Galinsky, Richard M. Stone, MD, Timothy A. Graubert, MD, Alex K. Shalek, PhD, Jon C. Aster, MD PhD, Andrew A. Lane, MD PhD, Bradley E. Bernstein, MD PhD

Blood (2018) 132 (Supplement 1): 542.

https://doi.org/10.1182/blood-2018-99-113502

Published: 2018

Journal Articles

Dissecting the Roles of p38β and p38γ in Cutaneous T Cell Lymphoma

Xu Hannah Zhang, PhD, Christiane Querfeld, MD PhD, Steven T Rosen

Blood (2018) 132 (Supplement 1): 2866.

https://doi.org/10.1182/blood-2018-99-118992

Published: 2018

Journal Articles

Autonomous Ca 2+ Oscillations Reflect Oncogenic BCR-Signaling in Multiple B-Cell Malignancies and Are Essential for Survival and Proliferation

Kohei Kume, PhD, Liting Chen, PhD, Jae-Woong Lee, PhD, Markus Muschen, MD

Blood (2018) 132 (Supplement 1): 1373.

https://doi.org/10.1182/blood-2018-99-117315

Published: 2018

Journal Articles

Rare Germline Variant in NFATC4 Associated with Familial Chronic Lymphocytic Leukemia

Gilad Itchaki, Grace Tiao, PhD, Ma Reina D. Improgo, PhD, Siddha Kasar, PhD, Bethany Tesar, MS, Stacey Marie Fernandes, BS, Nathalie Pochet, PhD, Emily M McWilliams, PhD, Harrison Bai, Arnold S. Freedman, MD, Gad Getz, PhD, Jennifer R. Brown, MD PhD

Blood (2017) 130 (Supplement 1): 2993.

https://doi.org/10.1182/blood.V130.Suppl_1.2993.2993

Published: 2017

Journal Articles

Ca 2+ Oscillations and NFATC1 -Activation Enable Oncogenic Signaling in Pre-B Cell Transformation and Leukemogenesis

Kohei Kume, PhD, Liting Chen, PhD, Jaewoong Lee, PhD, Markus Muschen, MD

Blood (2017) 130 (Supplement 1): 2500.

https://doi.org/10.1182/blood.V130.Suppl_1.2500.2500

Published: 2017

Journal Articles

Treg in GVHD Prophylaxis: Unique Transcription Factor Regulation of Foxp3 Expression in Itreg Derived from Human Umbilical Cord Blood (UCB) Vs Adult (AB) Naive CD4 T Cells

Jeong-Su Do, PhD, Fei Zhong, MD, Twishari Dasgupta, PhD, Wouter van't Hof, PhD, Marcie Finney, MS, Mary Laughlin, MD

Blood (2017) 130 (Supplement 1): 3191.

https://doi.org/10.1182/blood.V130.Suppl_1.3191.3191

Published: 2017

Journal Articles

Nuclear NFATc1 Causes Development of Fms-like Receptor Tyrosine Kinase 3 Receptor (FLT3) Internal Tandem Duplication Mutation-Positive (FLT3-ITD) Acute Myeloid Leukemia (AML) and Mediates Drug Resistance

Maria A. Solovey, Ying Wang, MD, Stefan Gattenloehner, MD, Elisabeth Hessmann, MD, Stephan Metzelder, MD, Christian Michel, MD, Volker Ellenrieder, MD, Joachim R. Goethert, MD, Andreas Neubauer, Andreas Burchert, MD

Blood (2016) 128 (22): 1722.

https://doi.org/10.1182/blood.V128.22.1722.1722

Published: 2016

Journal Articles

Averted NFATc1 Sumoylation in Alloreactive T Cells Ameliorates Acute GvHD

Musga Qureischi, MSc, Lena Dietz, PhD, Martin Vaeth, PhD, Andreas Beilhack, MD, Friederike Berberich-Siebelt, PD PhD

Blood (2016) 128 (22): 809.

https://doi.org/10.1182/blood.V128.22.809.809

Published: 2016

Journal Articles

The Impact of NFAT Inhibition on Neutrophil Effector Functions in Patients after Allogeneic Hematopoietic Stem Cell Transplantation and on Neutrophil Antifungal Defense and Myelopoiesis in Cyclosporin Α Treated and NFATc1 LysM Mice

Daniel Teschner, Katharina Plein, Christian Michel, Steve Pruefer, PhD, Matthias Bros, PhD, Eva Maria Wagner, MD, Matthias Theobald, MD, Hansjoerg Schild, PhD Prof., Markus Radsak, MD

Blood (2016) 128 (22): 3679.

https://doi.org/10.1182/blood.V128.22.3679.3679

Published: 2016

Journal Articles

Involvement of NFAT Transcription Factors in NK Cell Reactivity

Kathrin Rothfelder, MSc, Melanie Märklin, PhD, Julia Wild, MSc, Daniela Dörfel, MD, Lothar Kanz, MD, Martin R Müller, MD PhD, Helmut R. Salih, MD

Blood (2016) 128 (22): 1344.

https://doi.org/10.1182/blood.V128.22.1344.1344

Published: 2016

Journal Articles

MSMD Patients with IFN-g-STAT1 Signaling Defect Present Enhanced Osteoclastogenesis and Bone Resorption

Shiho Nishimura, MD, Miyuki Tsumura, PhD, Osamu Hirata, MD PhD, Reiko Kagawa, MD, Yoko Mizoguchi, MD PhD, Satoshi Okada, MD PhD, Masao Kobayashi, MD PhD

Blood (2015) 126 (23): 3591.

https://doi.org/10.1182/blood.V126.23.3591.3591

Published: 2015

Journal Articles

The Impact of NFAT Inhibition on Neutrophil Antifungal Defense and Myelopoiesis in Cyclosporine A Treated and NFATc1 LysM Mice

Daniel Teschner, MD, Christian Michel, MD, Steve Pruefer, PhD, Matthias Theobald, MD PhD, Hansjoerg Schild, PhD Prof., Markus Radsak, MD

Blood (2015) 126 (23): 1007.

https://doi.org/10.1182/blood.V126.23.1007.1007

Published: 2015

Journal Articles

A Role for NFAT in Innate Immunity: Neutrophil Effector Functions in Patients after Allogeneic Hematopoietic Stem Cell Transplantation Under Cyclosporine Α Treatment

Katharina Plein, Daniel Teschner, MD, Christian Michel, MD, Eva-Maria Wagner, MD, Pamela Stein, PhD, Matthias Theobald, MD Prof., Hansjoerg Schild, MD Prof., Markus Radsak, MD

Blood (2014) 124 (21): 2495.

https://doi.org/10.1182/blood.V124.21.2495.2495

Published: 2014

Journal Articles

Targeting B-cell anergy in chronic lymphocytic leukemia

Benedetta Apollonio, Cristina Scielzo, Maria Teresa Sabrina Bertilaccio, Elisa ten Hacken, Lydia Scarfò, Pamela Ranghetti, Freda Stevenson, Graham Packham, Paolo Ghia, Marta Muzio, Federico Caligaris-Cappio

Blood (2013) 121 (19): 3879–3888.

https://doi.org/10.1182/blood-2012-12-474718

Published: 2013

Includes: Supplemental data

Journal Articles

Macrophage Wnt-Calcineurin-Flt1 signaling regulates mouse wound angiogenesis and repair

James A. Stefater, III, Sujata Rao, Katie Bezold, Alfred C. Aplin, Roberto F. Nicosia, Jeffrey W. Pollard, Napoleone Ferrara, Richard A. Lang

Blood (2013) 121 (13): 2574–2578.

https://doi.org/10.1182/blood-2012-06-434621

Published: 2013

Includes: Supplemental data

Journal Articles

Targeting B Cell Anergy in Chronic Lymphocytic Leukemia

Benedetta Apollonio, Cristina Scielzo, Maria Teresa Sabrina Bertilaccio, Elisa ten Hacken, Lydia Scarfò, Paolo Ghia, Marta Muzio, Federico Caligaris-Cappio, MD

Blood (2012) 120 (21): 3863.

https://doi.org/10.1182/blood.V120.21.3863.3863

Published: 2012

Journal Articles

Involvement of NFAT Signaling in Function and Anti-Tumor Reactivity of NK Cells

Julia S Wild, Benjamin J Schmiedel, PhD, Melanie Märklin, Lothar Kanz, MD, Martin R Müller, MD, PhD, Helmut R Salih, MD

Blood (2012) 120 (21): 1887.

https://doi.org/10.1182/blood.V120.21.1887.1887

Published: 2012

NARROW

Role of Vav1 Genomic Alterations in T-Cell Differentiation and Transformation in Peripheral T-Cell Lymphoma

The Histone Demethylase KDM4A Is Required to Sustain H3K9me3/H3K27me3 Epigenetic States and Oncogenesis in MLL-AF9 Acute Myeloid Leukemia

Mechanism of Synergistic Effects on T Cell Activation By Avadomide (CC-122) and Nivolumab

Single-Cell RNA-Seq Reveals AML Cellular Hierarchies Relevant to Clinical Outcomes and Immunity

Dissecting the Roles of p38β and p38γ in Cutaneous T Cell Lymphoma

Autonomous Ca 2+ Oscillations Reflect Oncogenic BCR-Signaling in Multiple B-Cell Malignancies and Are Essential for Survival and Proliferation

Rare Germline Variant in NFATC4 Associated with Familial Chronic Lymphocytic Leukemia

Ca 2+ Oscillations and NFATC1 -Activation Enable Oncogenic Signaling in Pre-B Cell Transformation and Leukemogenesis

Treg in GVHD Prophylaxis: Unique Transcription Factor Regulation of Foxp3 Expression in Itreg Derived from Human Umbilical Cord Blood (UCB) Vs Adult (AB) Naive CD4 T Cells

Nuclear NFATc1 Causes Development of Fms-like Receptor Tyrosine Kinase 3 Receptor (FLT3) Internal Tandem Duplication Mutation-Positive (FLT3-ITD) Acute Myeloid Leukemia (AML) and Mediates Drug Resistance

Averted NFATc1 Sumoylation in Alloreactive T Cells Ameliorates Acute GvHD

The Impact of NFAT Inhibition on Neutrophil Effector Functions in Patients after Allogeneic Hematopoietic Stem Cell Transplantation and on Neutrophil Antifungal Defense and Myelopoiesis in Cyclosporin Α Treated and NFATc1 LysM Mice

Involvement of NFAT Transcription Factors in NK Cell Reactivity

MSMD Patients with IFN-g-STAT1 Signaling Defect Present Enhanced Osteoclastogenesis and Bone Resorption

The Impact of NFAT Inhibition on Neutrophil Antifungal Defense and Myelopoiesis in Cyclosporine A Treated and NFATc1 LysM Mice

A Role for NFAT in Innate Immunity: Neutrophil Effector Functions in Patients after Allogeneic Hematopoietic Stem Cell Transplantation Under Cyclosporine Α Treatment

Targeting B-cell anergy in chronic lymphocytic leukemia

Macrophage Wnt-Calcineurin-Flt1 signaling regulates mouse wound angiogenesis and repair

Targeting B Cell Anergy in Chronic Lymphocytic Leukemia

Involvement of NFAT Signaling in Function and Anti-Tumor Reactivity of NK Cells

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American Society of Hematology

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American Society of Hematology

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