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Journal Articles

Increase of Mitochondrial Activity Contributes to the Bortezomib-Relapsed in Multiple Myeloma, a Novel Therapeutic Opportunity

Alejandra Ortiz-Ruiz, BSc, Yanira Ruiz-Heredia, Mehmet Samur, PhD, Pedro Aguilar-Garrido, Maria Luz Morales, Antonio Valeri, PhD, Almudena Garcia-Ortiz, PhD, Santiago Barrio, PhD, Carmen Bárcena, Rosa Maria Garcia-Martin, Vanesa Garrido, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD, María Teresa Cedena, Joaquin Martinez-Lopez, MD PhD, Maria Linares, PhD, Miguel Gallardo, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4408.
https://doi.org/10.1182/blood-2019-123950
Published: 2019
Journal Articles

AML Cells Have Altered Mitochondrial Biogenesis and Low Spare Reserve Capacity in Their Respiratory Chain That Renders Them Susceptible to Oxidative Metabolic Stress.

Shrivani Sriskanthadevan, PhD, Timothy E Chung, Marko Skrtic, PhD, Bozhena Jhas, BSc, Rose Hurren, BSc, Marcela Gronda, MSc, Xiao Ming Wang, Yulia Jitkova, PhD, Mahadeo A. Sukhai, PhD, Feng-Hsu Lin, PhD, Neil Maclean, BSc, Rob C. Laister, PhD, Peter Mullen, PhD, Stephanie Xie, Linda Penn, PhD, Ian M. Rogers, PhD, John E. Dick, PhD $, Mark D. Minden, MD, PhD, Aaron D Schimmer, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2581.
https://doi.org/10.1182/blood.V120.21.2581.2581
Published: 2012
Journal Articles

Inhibition of Mitochondrial Translation As a Therapeutic Strategy for Acute Myeloid Leukemia (AML)

Marko Skrtic, BSc, Shrivani Sriskanthadevan, PhD, Bozhena Livak, BSc, Marinella Gebbia, PhD, Xiaoming Wang, Zezhou Wang, PhD, Rose Hurren, BSc, Yulia Jitkova, PhD, Marcela Gronda, MSc, Neil Maclean, BSc, Courteney Lai, BSc, Yanina Eberhard, BSc, PhD, Justyna Bartoszko, BSc, Paul A. Spagnuolo, PhD, Angela Rutledge, PhD, Alessandro Datti, PhD, Troy Ketela, Jason Moffat, Brian H Robinson, PhD, Jessie M Cameron, PhD, Jeff L. Wrana, PhD, Connie J. Eaves, PhD, Mark D. Minden, MD, PhD, Jean C.Y. Wang, MD, PhD, John E. Dick, PhD, R. Keith Humphries, MD, PhD, Corey Nislow, PhD, Guri Giaever, PhD, Aaron D Schimmer, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 233.
https://doi.org/10.1182/blood.V118.21.233.233
Published: 2011
Journal Articles

AML Cells Have Increased Mitochondrial Mass but Less Reserve in Their Respiratory Chain Complexes Leading to Heightened Sensitivity to Inhibition of Mitochondrial Protein Translation,

Shrivani Sriskanthadevan, PhD, Skrtic Marko, BSc, Bozhena Livak, BSc, Yulia Jitkova, PhD, Rose Hurren, BSc, Marcela Gronda, MSc, Rob Laister, PhD, Peter Mullen, PhD, Linda Penn, PhD, Mark D. Minden, MD, PhD, Aaron D Schimmer, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 3585.
https://doi.org/10.1182/blood.V118.21.3585.3585
Published: 2011