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Journal Articles

Anti-inflammatory activity of CD44 antibodies in murine immune thrombocytopenia is mediated by Fcγ receptor inhibition

Peter A. A. Norris, Gurleen Kaur, Ramsha Khan, Guangheng Zhu, Heyu Ni, Alan H. Lazarus

Blood (2021) 137 (15): 2114–2124.

https://doi.org/10.1182/blood.2020009497

Published: 2021

Includes: Supplemental data

Journal Articles

Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP

Ramsha Khan, Melissa Menard, Chao-Ching Jen, Xi Chen, Peter A. A. Norris, Alan H. Lazarus

Blood (2020) 135 (26): 2420–2424.

https://doi.org/10.1182/blood.2019003646

Published: 2020

Includes: Supplemental data

Journal Articles

Hemolysis in the Spleen Drives Erythrocyte Turnover

Thomas Klei, Robin Van Bruggen, PhD, Jill Dalimot, Martijn Veldthuis, Erik Mul, Timo Rademakers, Mark Hoogenboezem, Sietse Quirijn Nagelkerke, Wilfred Van Ijcken, Soren K. Moestrup, MD PhD, Floris van Alphen, Sander Meijer, PhD, Taco Kuijpers, Rob van Zwieten, Pia Svendsen

Blood (2019) 134 (Supplement_1): 946.

https://doi.org/10.1182/blood-2019-124342

Published: 2019

Journal Articles

Syk Plays an Essential Role in Phagosome-Lysosome Fusion By Facilitating Actin-Remodeling in Complement-Mediated Phagocytosis

Yumi Tohyama, PhD, Hiroyuki Tabata, PhD, Kaoru Tohyama, MD PhD

Blood (2019) 134 (Supplement_1): 2315.

https://doi.org/10.1182/blood-2019-125061

Published: 2019

Journal Articles

Glia Maturation Factor-γ Regulates Autophagy in Murine Macrophages

Wulin Aerbajinai, MD PhD, Jianqiong Zhu, MD, Chutima Kumkhaek, PhD, Kyung Chin, Griffin Rodgers, MD

Blood (2019) 134 (Supplement_1): 2318.

https://doi.org/10.1182/blood-2019-130318

Published: 2019

Journal Articles

Anti-CD20 Therapy Reliance on Antibody-Dependent Cellular Phagocytosis Affects Combination Drug Choice

Charles C. Chu, PhD, Jonathan J. Pinney, MS, Karl R. VanDerMeid, BS, Raquel Izumi, PhD, Veerendra Munugalavadla, PhD, Paul M. Barr, MD, Michael Rusty Elliott, PhD, Clive S Zent, MD

Blood (2019) 134 (Supplement_1): 682.

https://doi.org/10.1182/blood-2019-124901

Published: 2019

Journal Articles

Functionally Distinct Subsets of Monocytes in Mouse and Human Blood

Catherine S Rhee, PhD, Elizabeth W Scadden, Chea L Phillip, Bum-Kyu Lee, PhD, Meeta Mistry, Friedrich F Hoyer, MD, Hiroki Kato, MD PhD, Giovanna Mantica, Jonghwan Kim, PhD, Matthias Nahrendorf, PhD, Michael K Mansour, MD PhD, David B Sykes, MD PhD, David T. Scadden, MD

Blood (2019) 134 (Supplement_1): 438.

https://doi.org/10.1182/blood-2019-124054

Published: 2019

Journal Articles

Functional Characterization of Gamma Delta T Cells and Allogeneic Activated NK Cells As Effector Cells for Tafasitamab (MOR208)

Jung Hyun Her, Dominik Pretscher, Sungyoo Cho, Yu-Kyeong Hwang, Timm Hoeres, Rainer Boxhammer, Stefan Steidl, Maria Patra, Juergen Schanzer, Jan Endell

Blood (2019) 134 (Supplement_1): 3801.

https://doi.org/10.1182/blood-2019-128511

Published: 2019

Journal Articles

Mechanistic Characterization of Tafasitamab-Mediated Antibody-Dependent Cellular Phagocytosis Alone or in Combination with Lenalidomide

Dimitrios Mougiakakos, MD, Simon Voelkl, PhD, Christian Bach, Andrej Stoll, Katrin Bitterer, Fabian Beier, MD, Jan Endell, Rainer Boxhammer, Jörg Thomas Bittenbring, MD, Andreas Mackensen, MD, Heiko Bruns, PhD

Blood (2019) 134 (Supplement_1): 4064.

https://doi.org/10.1182/blood-2019-124886

Published: 2019

Journal Articles

Increase Expression of the Genes PADI4, MPO and ELANE in the Chronic Phase of DVT Patients

Isabella Macedo Toni, MSc, Kiara Zapponi, Bidossessi Wilfried Hounkpe, Beatriz Moraes Martinelli, BSc, Silmara Aparecida De Lima Montalvão, PhD, Erich V De Paula, MD PhD, Joyce Maria Annichino- Bizzacchi, MD PhD

Blood (2019) 134 (Supplement_1): 4921.

https://doi.org/10.1182/blood-2019-131916

Published: 2019

Journal Articles

Human neutrophils express low levels of FcγRIIIA, which plays a role in PMN activation

Josée Golay, Rut Valgardsdottir, Gerta Musaraj, Damiano Giupponi, Orietta Spinelli, Martino Introna

Blood (2019) 133 (13): 1395–1405.

https://doi.org/10.1182/blood-2018-07-864538

Published: 2019

Includes: Supplemental data

Journal Articles

Alteration of CD47 Expression in Human and Murine Tumor Models Changes M1/M2 Phagocytosis Effect in Vitro and In Vivo

Huajun Yang, Zhongliang Li, Beibei Tang, Zegen Wang, Phillip Wang, Henry Li, PhD, Mohamad A. Cherry, MDMS, Frank Xing

Blood (2018) 132 (Supplement 1): 2395.

https://doi.org/10.1182/blood-2018-99-120268

Published: 2018

Journal Articles

Targeted Inhibition of CD47-Sirp Alpha Requires Fc-Fc Gamma Receptor Interactions to Maximize Phagocytosis in T-Cell Lymphomas

Salvia Jain, MD, Alexandria Van Scoyk, Elizabeth A Morgan, MD, Andrew Matthews, MD, Kristen E. Stevenson, MS, Gail Newton, PhD, Anu K Autio, PhD, Marisa O. Peluso, MS, Rachel W O'Connor, BS, Alison M. Paterson, PhD, Pamela M. Holland, PhD, Francis W Luscinskas, PhD, David M Weinstock, MD

Blood (2018) 132 (Supplement 1): 339.

https://doi.org/10.1182/blood-2018-99-112986

Published: 2018

Journal Articles

Targeting CD47 and TNFAIP8 By Mir-155 Overcomes Drug Resistance and Inhibits Tumor Growth through Induction of Phagocytosis and Apoptosis in Multiple Myeloma

Nasrin Rastgoo, PhD, Jahangir Abdi, PhD, Maryam Pourabdollah, MD, Hong Chang, MD

Blood (2018) 132 (Supplement 1): 1923.

https://doi.org/10.1182/blood-2018-99-113057

Published: 2018

Journal Articles

Interleukin 4 Induces Macrophage-Mediated Phagocytosis of Leukemia Cells

Pablo Peña-Martínez, Mia Eriksson, PhD, Ramprasad Ramakrishnan, Marion Chapellier, PhD, Carl Högberg, PhD, Caroline Jansson, David Gisselsson Nord, MD PhD, Marcus Järås, PhD

Blood (2018) 132 (Supplement 1): 2730.

https://doi.org/10.1182/blood-2018-99-110606

Published: 2018

Journal Articles

Hemoglobin S Induces Exposure of Red Blood Cell Membrane Skeleton Microdomains Bearing Mannose That Stimulate Phagocytosis By Macrophages: A Molecular Basis for Hemolysis in Sickle Cell Disease but Protection Against Plasmodium Falciparum malaria

Blood (2018) 132 (Supplement 1): 3642.

https://doi.org/10.1182/blood-2018-99-117290

Published: 2018

Journal Articles

Fcγ Receptors I and III on Splenic Macrophages Mediate GPIIb/IIIa Autoantibody-Dependent Phagocytosis of Platelets in Human Immune Thrombocytopenia

Peter A. A. Norris, BSc, George B. Segel, MD, Ulrich J Sachs, MD PhD, Behnaz Bayat, PhD, Gestur Vidarsson, PhD, Rick Kapur, MDPhDMSc, Christine M. Cserti-Gazdewich, BSc, MD FRCPC, Jeannie Callum, MD, Yulia Lin, MD FRCPC, Richard Burack, MD PhD, John W Semple, PhD, Alan H Lazarus, PhD

Blood (2018) 132 (Supplement 1): 129.

https://doi.org/10.1182/blood-2018-99-117650

Published: 2018

Journal Articles

CD16A-Specific Tetravalent Bispecific Immune Cell Engagers Potently Induce Antibody-Dependent Cellular Phagocytosis (ADCP) on Macrophages

Susanne Wingert, PhD, Uwe Reusch, PhD, Armin Beez, Jens Pahl, PhD, Adelheid Cerwenka, PhD, Joachim Koch, PhD, Martin Treder, PhD

Blood (2018) 132 (Supplement 1): 1111.

https://doi.org/10.1182/blood-2018-99-118427

Published: 2018

Journal Articles

Tislelizumab (BGB-A317) for Relapsed/Refractory Classical Hodgkin Lymphoma: Preliminary Efficacy and Safety Results from a Phase 2 Study

Yuqin Song, MD PhD, Quanli Gao, MD, Huilai Zhang, PhD, Lei Fan, MD PhD, Jianfeng Zhou, PhD, Dehui Zou, MD, Wei Li, MD, Haiyan Yang, PhD, Ting Liu, MD, Quanshun Wang, MD PhD, Fangfang Lv, MD, Yu Yang, MD, Haiyi Guo, MD, Liudi Yang, MD, Rebecca Elstrom, MD, Jane Huang, MD, William Novotny, MD, Vivian Wei, PhD, Jun Zhu, MD PhD

Blood (2018) 132 (Supplement 1): 682.

https://doi.org/10.1182/blood-2018-99-117848

Published: 2018

Journal Articles

Ibrutinib blocks Btk-dependent NF-ĸB and NFAT responses in human macrophages during Aspergillus fumigatus phagocytosis

Amelia Bercusson, Thomas Colley, Anand Shah, Adilia Warris, Darius Armstrong-James

Blood (2018) 132 (18): 1985–1988.

https://doi.org/10.1182/blood-2017-12-823393

Published: 2018

Includes: Supplemental data

NARROW

Anti-inflammatory activity of CD44 antibodies in murine immune thrombocytopenia is mediated by Fcγ receptor inhibition

Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP

Hemolysis in the Spleen Drives Erythrocyte Turnover

Syk Plays an Essential Role in Phagosome-Lysosome Fusion By Facilitating Actin-Remodeling in Complement-Mediated Phagocytosis

Glia Maturation Factor-γ Regulates Autophagy in Murine Macrophages

Anti-CD20 Therapy Reliance on Antibody-Dependent Cellular Phagocytosis Affects Combination Drug Choice

Functionally Distinct Subsets of Monocytes in Mouse and Human Blood

Functional Characterization of Gamma Delta T Cells and Allogeneic Activated NK Cells As Effector Cells for Tafasitamab (MOR208)

Mechanistic Characterization of Tafasitamab-Mediated Antibody-Dependent Cellular Phagocytosis Alone or in Combination with Lenalidomide

Increase Expression of the Genes PADI4, MPO and ELANE in the Chronic Phase of DVT Patients

Human neutrophils express low levels of FcγRIIIA, which plays a role in PMN activation

Alteration of CD47 Expression in Human and Murine Tumor Models Changes M1/M2 Phagocytosis Effect in Vitro and In Vivo

Targeted Inhibition of CD47-Sirp Alpha Requires Fc-Fc Gamma Receptor Interactions to Maximize Phagocytosis in T-Cell Lymphomas

Targeting CD47 and TNFAIP8 By Mir-155 Overcomes Drug Resistance and Inhibits Tumor Growth through Induction of Phagocytosis and Apoptosis in Multiple Myeloma

Interleukin 4 Induces Macrophage-Mediated Phagocytosis of Leukemia Cells

Hemoglobin S Induces Exposure of Red Blood Cell Membrane Skeleton Microdomains Bearing Mannose That Stimulate Phagocytosis By Macrophages: A Molecular Basis for Hemolysis in Sickle Cell Disease but Protection Against Plasmodium Falciparum malaria

Fcγ Receptors I and III on Splenic Macrophages Mediate GPIIb/IIIa Autoantibody-Dependent Phagocytosis of Platelets in Human Immune Thrombocytopenia

CD16A-Specific Tetravalent Bispecific Immune Cell Engagers Potently Induce Antibody-Dependent Cellular Phagocytosis (ADCP) on Macrophages

Tislelizumab (BGB-A317) for Relapsed/Refractory Classical Hodgkin Lymphoma: Preliminary Efficacy and Safety Results from a Phase 2 Study

Ibrutinib blocks Btk-dependent NF-ĸB and NFAT responses in human macrophages during Aspergillus fumigatus phagocytosis

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American Society of Hematology

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American Society of Hematology

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