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Journal Articles

The Protein Kinase C Inhibitor MS-553 for the Treatment of Chronic Lymphocytic Leukemia

Elizabeth M. Muhowski, Amy M. Lehman, M.A.S, Sean D. Reiff, PhD, Janani Ravikrishnan, Rose Mantel, Shrilekha Misra, Michael Niesman, PhD, Kai Zhang, MD, James S. Blachly, MD, Deepa Sampath, PhD, John C. Byrd, MD, Jennifer Woyach, MD

Blood (2019) 134 (Supplement_1): 2077.

https://doi.org/10.1182/blood-2019-128871

Published: 2019

Journal Articles

MRTFA Augments Megakaryocyte Maturation By Enhancing the SRF Regulatory Axis

Nur-Taz Rahman, BS, MPhil, Vincent P Schulz, PhD, Lin Wang, MS, Patrick G. Gallagher, MD, Oleg Denisenko, PhD, Francesco Gualdrini, PhD, Esnault Cyril, PhD, Diane S. Krause, MD PhD

Blood (2018) 132 (Supplement 1): 640.

https://doi.org/10.1182/blood-2018-99-118954

Published: 2018

Journal Articles

Specific Gtpase Dynamin Isoforms Regulate Megakaryocyte Membrane Remodeling and The Formation Of Multivesicular Bodies and Microparticles

Yolande Chen, MD, Arinola Awomolo, MD, Jorie Aardema, BS, Michael Hession, Francisco Javier Gonzalez, MD, Hilary Christensen, Walter H. Kahr, MD, PhD, Seth J. Corey, MD, MPH

Blood (2013) 122 (21): 3529.

https://doi.org/10.1182/blood.V122.21.3529.3529

Published: 2013

Journal Articles

Targeting The T Cell Component Of The Tumour Microenvironment In Chronic Lymphocytic Leukaemia; A Potential Therapeutic Strategy

Kirsty M Cuthill, MBBS, MRCP, FRCPath, Andrea Gail Sherman Buggins, Ph.D., Pj Chana, Stephen Devereux, FRCP, FRCPath, PhD

Blood (2013) 122 (21): 4147.

https://doi.org/10.1182/blood.V122.21.4147.4147

Published: 2013

Journal Articles

Sirolimus Plus MEC Chemotherapy Has Significant Activity in High Risk AML Patients Especially Those Who Exhibit in Vivo Inhibition of the mTOR Pathway

Blood (2012) 120 (21): 143.

https://doi.org/10.1182/blood.V120.21.143.143

Published: 2012

Journal Articles

Single-Cell Pharmacodynamic Monitoring of Ribosomal Protein S6 Phosphorylation During AC220 Therapy Demonstrates in Vivo FLT3 Inhibition in Circulating Leukemic Blasts and Accurately Detects the Development of AC220 Resistance.

Alexander E Perl, MD, Grace R Jeschke, Catherine C Smith, MD, James K. Mangan, MD, PhD, Selina M. Luger, MD, Martin Carroll, MD

Blood (2012) 120 (21): 2453.

https://doi.org/10.1182/blood.V120.21.2453.2453

Published: 2012

Journal Articles

Lipopolysaccharide(LPS)-Induction of the HTLV-1 LTR in Monocytes

Junichi Tsukada, Takehiro Higashi, Atsushi Iwashige, Takefumi Katsuragi, Naho Nomura, Takahiro Yamaguchi, Tsukasa Nakanishi, Noriaki Kitamura, Ai Kawahara, Yasuhiro Yoshida, Hiroaki Morimoto

Blood (2011) 118 (21): 2167.

https://doi.org/10.1182/blood.V118.21.2167.2167

Published: 2011

Journal Articles

Single-Cell Pharmacodynamic Monitoring of S6 Ribosomal Protein in AML Blasts During Trials Combining Sirolimus and Intensive Chemotherapy: Target Inhibition Enhances Response

Margaret Kasner, MD, Selina M. Luger, MD, Grace R Jeschke, Rosemarie Mick, MS, Martin Carroll, MD, Alexander E Perl, MD

Blood (2011) 118 (21): 230.

https://doi.org/10.1182/blood.V118.21.230.230

Published: 2011

Journal Articles

CIP4-Dependent Defects in Platelet Biogenesis Involve Changes in Membrane Rigidity Independently of WASP

Yolande Chen, MD, Jorie Aardema, BS, Sayali Kale, Arinola Awomolo, BS, Zak Whichard, Ted Strom, MD, PhD, David Rawlings, MD, Seth J. Corey, MD

Blood (2011) 118 (21): 705.

https://doi.org/10.1182/blood.V118.21.705.705

Published: 2011

Journal Articles

Phospho-Specific Flow Cytometry of Fixed Whole Blood Demonstrates In Vivo FLT3 Inhibition in Circulating Leukemic Blasts During AC220 Therapy and Accurately Detects the Development of Therapeutic Resistance,

Alexander E Perl, MD, Grace R Jeschke, Catherine C. Smith, MD, James K. Mangan, MD, PhD, Selina M. Luger, MD, Martin Carroll, MD

Blood (2011) 118 (21): 3502.

https://doi.org/10.1182/blood.V118.21.3502.3502

Published: 2011

Journal Articles

Identification of a Region within the Cytoplasmic Domain of Sema4D That Binds Calmodulin and Regulates Shedding of the Sema4D Exodomain in Platelets,

Peipei Mou, BS, Zhao Zeng, BS, Lijie Ren, MS, Qiang Li, BS, Kenneth M Wannemacher, PhD, Xi Mo, PhD, Lawrence F. Brass, MD, PhD, Li Zhu, MD, PhD

Blood (2011) 118 (21): 3249.

https://doi.org/10.1182/blood.V118.21.3249.3249

Published: 2011

Journal Articles

Phospho-Specific Flow Cytometry of Fixed Whole Blood During AML Clinical Trials to Monitor In Vivo FLT3 Inhibition in Leukemic Blasts,

Alexander E Perl, MD, Grace R Jeschke, Takashi Sato, Shiro Akinaga, Niranjan S. Rao, PhD, Maria R. Baer, MD, Mark J. Levis, MD, PhD, Martin Carroll, MD

Blood (2011) 118 (21): 3508.

https://doi.org/10.1182/blood.V118.21.3508.3508

Published: 2011

Journal Articles

Maitake Mushroom Extract in Myelodysplastic Syndrome (MDS): A Phase II Study

Kathleen M. Wesa, MD, Virginia M. Klimek, M.D., Susanna Cunningham-Rundles, PhD, Allison Hirsch, Emily K. Dolezal, Gria N Jacobs, Marci I Coleton, MA, Stephen D. Nimer, MD, Barrie R. Cassileth, PhD

Blood (2011) 118 (21): 5043.

https://doi.org/10.1182/blood.V118.21.5043.5043

Published: 2011

Journal Articles

C/EBP and AP-1 Proteins Form Leucine Zipper Heterodimers and Reduce C/EBP Homodimer Formation During Monopoiesis.

SunHwa Hong, Ph.D., Alan D. Friedman, M.D.

Blood (2010) 116 (21): 2606.

https://doi.org/10.1182/blood.V116.21.2606.2606

Published: 2010

Journal Articles

A Molecular Mechanism of Tumor Mediated Suppression of Dendritic Cell Differentiation

Matthew R Farren, Louise Carlson, Haley Spangler, Kelvin P Lee, MD

Blood (2010) 116 (21): 1735.

https://doi.org/10.1182/blood.V116.21.1735.1735

Published: 2010

Journal Articles

Tyrosine Phosphorylation of Runx1 In Megakaryocytes by Src Family Kinases

Hui Huang, Zachary Waldon, Gordon Chan, Helen Zhu, Hanno Steen, Gen-Sheng Feng, Benjamin Neel, Alan Cantor

Blood (2010) 116 (21): 742.

https://doi.org/10.1182/blood.V116.21.742.742

Published: 2010

Journal Articles

A Comparative Analysis of Immune Reconstitution Following Reduced Intensity Conditioning with CAMPATH-1H and Total Lymphoid Irradiation/Anti-Thymocyte Globulin Prior to Allogeneic Stem Cell Transplantation.

Brett Glotzbecker, MD, Heidi Mills, BA, Jacalyn Rosenblatt, MD, Zekui Wu, MD, Kerry Wellenstein, Baldev Vasir, PhD, Robin Joyce, MD, James D. Levine, MD, Dimitrios Tzachanis, MD, PhD, Jeffrey Zwicker, M.D., Vassiliki A Boussiotis, MD, PhD, Mary Ann Stevenson, MD, Thomas Spitzer, MD, Carol Delaney, Jessica Bonhoff, BA, Nancy Giallombardo, NP, Katharine Conway, NP, David F. McDermott, MD, David Avigan, MD

Blood (2009) 114 (22): 1148.

https://doi.org/10.1182/blood.V114.22.1148.1148

Published: 2009

Journal Articles

Calpain Regulates ADAM17-Mediated Platelet Glycoprotein Ibalpha Ectodomain Shedding.

Rong Yan, Zhicheng Wang, Weilin Zhang, Suping Li, Changgeng Ruan, MD, PhD, Kesheng Dai

Blood (2009) 114 (22): 2996.

https://doi.org/10.1182/blood.V114.22.2996.2996

Published: 2009

Journal Articles

A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity

Juan D. Matute, Andres A. Arias, Nicola A. M. Wright, Iwona Wrobel, Christopher C. M. Waterhouse, Xing Jun Li, Christophe C. Marchal, Natalie D. Stull, David B. Lewis, MacGregor Steele, James D. Kellner, Weiming Yu, Samy O. Meroueh, William M. Nauseef, Mary C. Dinauer

Blood (2009) 114 (15): 3309–3315.

https://doi.org/10.1182/blood-2009-07-231498

Published: 2009

Includes: Supplemental data

Journal Articles

Phorbol ester–induced PKCϵ down-modulation sensitizes AML cells to TRAIL-induced apoptosis and cell differentiation

Giuliana Gobbi, Prisco Mirandola, Cecilia Carubbi, Cristina Micheloni, Chiara Malinverno, Paolo Lunghi, Antonio Bonati, Marco Vitale

Blood (2009) 113 (13): 3080–3087.

https://doi.org/10.1182/blood-2008-03-143784

Published: 2009

Includes: Supplemental data

NARROW

The Protein Kinase C Inhibitor MS-553 for the Treatment of Chronic Lymphocytic Leukemia

MRTFA Augments Megakaryocyte Maturation By Enhancing the SRF Regulatory Axis

Specific Gtpase Dynamin Isoforms Regulate Megakaryocyte Membrane Remodeling and The Formation Of Multivesicular Bodies and Microparticles

Targeting The T Cell Component Of The Tumour Microenvironment In Chronic Lymphocytic Leukaemia; A Potential Therapeutic Strategy

Sirolimus Plus MEC Chemotherapy Has Significant Activity in High Risk AML Patients Especially Those Who Exhibit in Vivo Inhibition of the mTOR Pathway

Single-Cell Pharmacodynamic Monitoring of Ribosomal Protein S6 Phosphorylation During AC220 Therapy Demonstrates in Vivo FLT3 Inhibition in Circulating Leukemic Blasts and Accurately Detects the Development of AC220 Resistance.

Lipopolysaccharide(LPS)-Induction of the HTLV-1 LTR in Monocytes

Single-Cell Pharmacodynamic Monitoring of S6 Ribosomal Protein in AML Blasts During Trials Combining Sirolimus and Intensive Chemotherapy: Target Inhibition Enhances Response

CIP4-Dependent Defects in Platelet Biogenesis Involve Changes in Membrane Rigidity Independently of WASP

Phospho-Specific Flow Cytometry of Fixed Whole Blood Demonstrates In Vivo FLT3 Inhibition in Circulating Leukemic Blasts During AC220 Therapy and Accurately Detects the Development of Therapeutic Resistance,

Identification of a Region within the Cytoplasmic Domain of Sema4D That Binds Calmodulin and Regulates Shedding of the Sema4D Exodomain in Platelets,

Phospho-Specific Flow Cytometry of Fixed Whole Blood During AML Clinical Trials to Monitor In Vivo FLT3 Inhibition in Leukemic Blasts,

Maitake Mushroom Extract in Myelodysplastic Syndrome (MDS): A Phase II Study

C/EBP and AP-1 Proteins Form Leucine Zipper Heterodimers and Reduce C/EBP Homodimer Formation During Monopoiesis.

A Molecular Mechanism of Tumor Mediated Suppression of Dendritic Cell Differentiation

Tyrosine Phosphorylation of Runx1 In Megakaryocytes by Src Family Kinases

A Comparative Analysis of Immune Reconstitution Following Reduced Intensity Conditioning with CAMPATH-1H and Total Lymphoid Irradiation/Anti-Thymocyte Globulin Prior to Allogeneic Stem Cell Transplantation.

Calpain Regulates ADAM17-Mediated Platelet Glycoprotein Ibalpha Ectodomain Shedding.

A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity

Phorbol ester–induced PKCϵ down-modulation sensitizes AML cells to TRAIL-induced apoptosis and cell differentiation

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American Society of Hematology

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American Society of Hematology

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