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Journal Articles

iPLA2β Contributes to Activation of Human and Mouse Platelets Via ITAM Receptors Fcγ RIIA and GPVI

Shaji Abraham, PhD, Pravin Patel, BA, Ulhas P. Naik, PhD, Steven Edward McKenzie, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2339.
https://doi.org/10.1182/blood-2019-128426
Published: 2019
Journal Articles

Hyperphosphatemia Contributes to Inflammation and Iron Dysregulation in Models of Normal and Impaired Renal Function

Brian Czaya, BS, MSc, Beatrice Richter, PhD, Christopher Yanucil, Bsc, Isaac Campos, Bsc, Kylie Heitman, Bsc, Christian Faul, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2238.
https://doi.org/10.1182/blood-2019-122144
Published: 2019
Journal Articles

Characteristics of Serum Lipidome in Patients with POEMS Syndrome

Hao Zhao, MD, Xue-min Gao, Xinxin Cao, MD, Lu Zhang, MD, Dao-Bin Zhou, Jian Li, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3082.
https://doi.org/10.1182/blood-2019-122239
Published: 2019
Journal Articles

Combination of Gatekeeper Mutations and Cysteine 481 Replacement Causes Super Resistance to the Irreversible BTK Inhibitors Ibrutinib, Acalabrutinib and Zanubrutinib

Hernando Yesid Estupiñan Velasquez, Yuye Shi, MD PhD, Dara K. Mohammad, PhD, Qing Wang, Mauno Vihinen, PhD, Rula Zain, PhD, Anna Berglöf, PhD VMD, Edvard CI Smith, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5759.
https://doi.org/10.1182/blood-2019-123398
Published: 2019
Journal Articles

Prevalence of BTK and PLCG2 mutations in a real-life CLL cohort still on ibrutinib after 3 years: a FILO group study

Brief Report
Anne Quinquenel, Luc-Matthieu Fornecker, Rémi Letestu, Loïc Ysebaert, Carole Fleury, Grégory Lazarian, Marie-Sarah Dilhuydy, Delphine Nollet, Romain Guieze, Pierre Feugier, Damien Roos-Weil, Lise Willems, Anne-Sophie Michallet, Alain Delmer, Katia Hormigos, Vincent Levy, Florence Cymbalista, Fanny Baran-Marszak
Journal: Blood
Blood (2019) 134 (7): 641–644.
https://doi.org/10.1182/blood.2019000854
Published: 2019
Includes: Supplemental data
Journal Articles

Genomic Analysis of Ibrutinib Resistance in Waldenstrom Macroglobulinemia

Cristina Jimenez, PhD, Gloria G Chan, MS, Lian Xu, MS, Nickolas Tsakmaklis, Jiaji G Chen, Maria Demos, Amanda Kofides, Maria Luisa Guerrera, MD, Xia Liu, MD, Manit Munshi, MS, Joshua Gustine, MPH, Guang Yang, PhD, Jorge J. Castillo, MD, Steven P Treon, MD PhD FRCP, Zachary R Hunter, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1372.
https://doi.org/10.1182/blood-2018-99-118819
Published: 2018
Journal Articles

SNP-Array Genome Wide Association Study Meta-Analysis Identifies Innate Immune Susceptibility Loci Associated with Non-Del(5q) Myelodysplastic Syndromes Predisposition

Kathy L McGraw, PhD, Chia-Ho Cheng, PhD, Y. Ann Chen, PhD, Hsin-An Hou, MD PhD, Guilio Genovese, PhD, Thomas Cluzeau, MD PhD, Andrea Pellagatti, PhD, Bartlomiej Przychodzen, Mar Mallo, PhD, Arenillas Leonor, MD PhD, Azim M. Mohamedali, PhD, Lionel Ades, MD PhD, David A Sallman, MD, Eric Padron, MD, Lubomir Sokol, MD PhD, Chimene Moreilhon, Sophie Raynaud, MD PhD, Bjorn Nilsson, PhD, Hwei-Fang Tien, MD, PhD, Jacqueline Boultwood, PhD, Benjamin L. Ebert, MDPhD, Francesc Sole, PhD, Pierre Fenaux, MD PhD, Ghulam Mufti, Jaroslaw P. Maciejewski, Peter Kanetsky, PhD, Alan F. List, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 107.
https://doi.org/10.1182/blood-2018-99-118747
Published: 2018
Journal Articles

Spatial Convergent Clonal Evolution Leading to Ibrutinib Resistance and Disease Progression in Chronic Lymphocytic Leukemia

Richárd Kiss, Donát Alpár, PhD, Ambrus Gángó, MD, Noémi Nagy, Dora Aczel, Andras Matolcsy, MD PhD, Judit Csomor, Zoltán Mátrai, MD PhD, Csaba Bödör, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5539.
https://doi.org/10.1182/blood-2018-99-115937
Published: 2018
Journal Articles

GPVI signaling is compromised in newly formed platelets after acute thrombocytopenia in mice

Brief Report
Shuchi Gupta, Deya Cherpokova, Markus Spindler, Martina Morowski, Markus Bender, Bernhard Nieswandt
Journal: Blood
Blood (2018) 131 (10): 1106–1110.
https://doi.org/10.1182/blood-2017-08-800136
Published: 2018
Includes: Supplemental data
Journal Articles

Differential Use of the Signaling Molecules BTK and PLC-γ in Mast Cells Stimulated Via the Receptors FcεRI and KIT

Anne Simonowski, MD, Carolin Zorn, PhD, Michael Huber, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2270.
https://doi.org/10.1182/blood.V130.Suppl_1.2270.2270
Published: 2017
Journal Articles

Systemic Biomarkers Show Elevated Oxidative Stress and Chronic Inflammation in Two Disorders of Neurodegeneration with Brain Iron Accumulation (NBIA)

Michael Minkley, BSc, Nancy Sweeters, PNP, Shiva Kasravi, BS, Jennifer Ferguson, BS MS, Annie Higa, BS, Angela Jackson, BSc MSc, Derek Smith, BS MS, Christoph Borchers, PhD, Raad Nashmi, PhD, Patrick Macleod, MD, Lynne D. Neumayr, MD, Elliott Vichinsky, MD, Patrick B Walter, MSc, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 943.
https://doi.org/10.1182/blood.V130.Suppl_1.943.943
Published: 2017
Journal Articles

Phospholipase Cgamma Pathway-Dependent mTOR Signaling Controls IL-7-Mediated Early B Cell Development

Mei Yu, PhD, Chen Yuhong, PhD, Hu Zeng, PhD, Yongwei Zheng, PhD, Guoping Fu, PhD, Wen Zhu, Ulrich Broeckel, MD, Praful Aggarwal, Amy Turner, Geoffrey A.M. Neale, PhD, Nan Zhu, PhD, Hongbo Chi, PhD, Renren Wen, PhD, Demin Wang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 620.
https://doi.org/10.1182/blood.V130.Suppl_1.620.620
Published: 2017
Journal Articles

Protein Kinase C-Dependent Von Willebrand Factor Secretion Is a Dual-Phased Process That Originates from 2 Distinct Intracellular Compartments

Laura Knipe, Nicola Hellen, PhD, Ianina Conte, PhD, Marjon Mourik, PhD, Aina Masgrau-Fortuny, PhD, Bijal Patel, PhD, Sayibrinthan Vickneswaran, Matthew Hannah, PhD, Tom Carter, PhD, Ruben Bierings, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1020.
https://doi.org/10.1182/blood.V130.Suppl_1.1020.1020
Published: 2017
Journal Articles

Cytoplasmic Phospholipase A2 Is Essential in GPVI Signaling Initiated Procoagulant Platelet Formation

Andaleb Kholmukhamedov, MD, Janecke Rae, Shawn M. Jobe, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1068.
https://doi.org/10.1182/blood.V130.Suppl_1.1068.1068
Published: 2017
Journal Articles

Ups and downs of the ADP phosphoproteome

Zoltan Nagy, Yotis A. Senis
Journal: Blood
Blood (2017) 129 (2): 135–136.
https://doi.org/10.1182/blood-2016-11-751917
Published: 2017
Journal Articles

Novel Evidence That Hematopoietic-Specific PLC-β2 Is Required for Normal Homing and Engraftment of Hematopoietic Stem Cells

Mateusz Adamiak, MS, Ahmed Abdelbaset Ismail, PhD, Ahmed Abdel-Latif, MD PhD, Janina Ratajczak, MD PhD, Magdalena Kucia, PhD, Mariusz Z Ratajczak, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3342.
https://doi.org/10.1182/blood.V128.22.3342.3342
Published: 2016
Journal Articles

Impaired GPVI Mediated Platelet Functional Responses and Signaling in CD45 Knockout Mice

Vaishali Inamdar, John Kostyak, PhD, Rachit Badolia, PhD, Carol Dangelmaier, Soochong Kim, PhD, Bhanukanth Manne, Satya P. Kunapuli, PhD
Journal: Blood
Blood (2016) 128 (22): 1355.
https://doi.org/10.1182/blood.V128.22.1355.1355
Published: 2016
Journal Articles

Novel Evidence That a Lipolytic Enzyme - Hematopoietic-Specific Phospholipase C Beta 2 - Promotes Mobilization of Hematopoietic Stem Cells By Decreasing Their Lipid Raft-Mediated Bone Marrow Retention and Increasing the Pro-Mobilizing Effects of Granulocytes

Mateusz Adamiak, MS, Agata Poniewierska-Baran, PhD, Gabriela Schneider, PhD, Ahmed Abdelbaset-Ismail, PhD, Malwina Suszynska, PhD, Ahmed Abdel-Latif, MD PhD, Magdalena Kucia, PhD, Janina Ratajczak, MD PhD, Mariusz Z Ratajczak, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1896.
https://doi.org/10.1182/blood.V126.23.1896.1896
Published: 2015
Journal Articles

Elucidation of Mild Bleeding Disorders Reported Under Ibrutinib (Imbruvica(R)) Therapy: Implications for Optimal Clinical Management

Loic Ysebaert, Marie Levade, PhD, Garcia Cedric, Anne-Sophie Michallet, MD PhD, Constantine Tam, MD, Sie Pierre, MDPhD, Bernard Payrastre
Journal: Blood
Blood (2014) 124 (21): 3296.
https://doi.org/10.1182/blood.V124.21.3296.3296
Published: 2014
Journal Articles

AVL-292, a Bruton's Tyrosine Kinase Inhibitor Impacts Bone Resorption by Abrogating Osteoclast Sealing Zone Formation in Multiple Myeloma

Homare Eda, Loredana Santo, Diana Cirstea, Andrew J. Yee, Anuj Mahindra, Tyler Scullen, Neeharika Nemani, Yuko Mishima, Erica Evans, Juswinder Singh, Wes Westlin, Noopur Raje
Journal: Blood
Blood (2012) 120 (21): 1822.
https://doi.org/10.1182/blood.V120.21.1822.1822
Published: 2012