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Journal Articles

Efficacy of Methoxsalen Sterile Solution in Conjunction with the Therakos ® Cellex ® Photopheresis System in Pediatric Patients with Steroid-Refractory Acute GvHD: Interim Analysis

Carrie Kitko, MD, Stefania Gaspari, MD, Henri Boodée

Blood (2019) 134 (Supplement_1): 4524.

https://doi.org/10.1182/blood-2019-124061

Published: 2019

Journal Articles

Blockade of Yes-Associated Protein As a Novel Therapeutic Approach in Diffuse Large B-Cell Lymphoma

Xiangxiang Zhou, MD, Juan Yang, MM, Ya Zhang, MD, Ying Li, MD, Xiaosheng Fang, MD, Na Chen, MD, Xin Wang, MD PhD

Blood (2019) 134 (Supplement_1): 808.

https://doi.org/10.1182/blood-2019-129695

Published: 2019

Journal Articles

Vitamin K5 Is an Efficient Photosensitizer for Ultraviolet a Light Inactivation of Bacteria

Fei Xu, Ying Li, Justen Jones, Jaroslav Vostal

Blood (2017) 130 (Supplement 1): 3744.

https://doi.org/10.1182/blood.V130.Suppl_1.3744.3744

Published: 2017

Journal Articles

Targeting T Cell Bioenergetics By Modulating P-Glycoprotein Selectively Depletes Alloreactive T Cells to Prevent Graft-Versus-Host Disease While Maintaining Antitumor Immunity

Zachariah McIver, DO, PhD, Rebecca Blevins, BS, Benjamin Coe, BS, Jason Grayson, PhD

Blood (2017) 130 (Supplement 1): 4456.

https://doi.org/10.1182/blood.V130.Suppl_1.4456.4456

Published: 2017

Journal Articles

P-Glycoprotein Modulation Facilitates the Selective Inhibition of Oxidative Phosphorylation in Alloreactive T Cells to Prevent Graft-Versus-Host Disease after Hematopoietic Stem Cell Transplant

Zachariah A. McIver, DO, James P Phipps, MS, Jason M Grayson, PhD, Jacqueline E Hill, Gregory A Schamerhorn, PhD, Tymish Y Ohulchanskyy, PhD, Michelle K Linder, Kellie S Davies, Roy S Weiner, MD, Michael R Detty, PhD

Blood (2015) 126 (23): 1879.

https://doi.org/10.1182/blood.V126.23.1879.1879

Published: 2015

Journal Articles

A Photosensitizer Verteporfin Has Light-Independent Anti-Leukemic Activity for Ph-Positive Acute Lymphoblastic Leukemia and Synergistically Works with Dasatinib in Vivo

Takanobu Morishita, MD, Fumihiko Hayakawa, MD PhD, Keiki Sugimoto, PhD, Daiki Hirano, MD, Yuki Kojima, MD, Naoto Imoto, MD, Yuichiro Inagaki, MD, Tomoki Naoe, MDPhD, Hitoshi Kiyoi, MD PhD

Blood (2015) 126 (23): 1331.

https://doi.org/10.1182/blood.V126.23.1331.1331

Published: 2015

Journal Articles

Description of New More Effective Photochemotherapeutic Compounds for Improving Effectiveness of Extracorporeal Photopheresis

David Garcia-Bernal, PhD, Miguel Blanquer Blanquer, MD PhD, Maria del Carmen Algueró, PhD, Jose Antonio del Rio, PhD, Enrique Correal, PhD, Rosa Yañez, MD, María Luisa Lamana, MD, Jose María Moraleda, MD

Blood (2014) 124 (21): 4124.

https://doi.org/10.1182/blood.V124.21.4124.4124

Published: 2014

Journal Articles

Vitamin K3 Is a Potential Ultraviolet Photosensitizer for Pathogen Reduction of Human Platelets and Plasma

Fei Xu, PhD, Jaroslav Vostal, MD, PhD

Blood (2012) 120 (21): 3434.

https://doi.org/10.1182/blood.V120.21.3434.3434

Published: 2012

Journal Articles

Nanoparticles – a Novel Approach to Chronic Lymphocytic Leukemia Treatment?

Ida Franiak-Pietryga, PhD, Ewelina Ziolkowska, MSc, Barbara Ziemba, PhD, Dietmar Appelhans, PhD, Brigitte Voit, Prof., Joanna Gora-Tybor, Prof., Tadeusz Robak, Prof., Barbara Klajnert, Prof., Maria Bryszewska, Prof.

Blood (2012) 120 (21): 4601.

https://doi.org/10.1182/blood.V120.21.4601.4601

Published: 2012

Journal Articles

Selective Depletion of T Cell Alloresponses Using a Photodepletion Strategy Preferentially Targets CD4+ T Cells.

Zachariah A. McIver, DO, Andrew Grim, BS, Nicolas Naguib, BS, Hahn Khuu, Minoo Battiwalla, MD, MS, David Stroncek, MD, A. John Barrett, MD

Blood (2010) 116 (21): 1467.

https://doi.org/10.1182/blood.V116.21.1467.1467

Published: 2010

Journal Articles

Photodynamic Therapy (PDT)-Mediated Inhibition of the Transcription Factor Yin Yang 1 (YY1) That Regulates Resistance In Lymphoma

Valentina Rapozzi, Ph.D, Sara Huerta-Yepez, PhD, Abhijeet Joshi, Mario I. Vega, PhD, Stavroula Baritaki, PhD, Luigi E. Xodo, Ph.D, Benjamin Bonavida, PhD

Blood (2010) 116 (21): 5113.

https://doi.org/10.1182/blood.V116.21.5113.5113

Published: 2010

Journal Articles

Selectively T Cell Depleted Allografts From HLA-Matched Sibling Donors Followed by Low-Dose Post Transplant Immunosuppression to Limit Disease Relapse In Patients with Hematological Malignancies

Zachariah A. McIver, DO, Stephan Mielke, MD, Aarthi Shenoy, MD, Vicki Fellows, David Stroncek, MD, Susan Leitman, MD, Richard Childs, MD, Minoo Battiwalla, MD, MS, Eleftheria K. Koklanaris, BS, Janice Haggerty, RN, Bipin N. Savani, MD, Katy Rezvani, A. John Barrett, MD

Blood (2010) 116 (21): 4705.

https://doi.org/10.1182/blood.V116.21.4705.4705

Published: 2010

Journal Articles

Allografts Selectively Photodepleted of GvHD Causing T Cells and Followed by Low-Level Immunosuppression: A Novel Method to Improve Disease Control After HLA-Matched Sibling Transplantations.

Stephan Mielke, MD, Aarthi Shenoy, MD, Katayoun Rezvani, MD, PhD, Agnes S. M. Yong, MD, PhD, Zachariah A. McIver, DO, Vicki S. Fellowes, Bipin N. Savani, MD, Roger Kurlander, MD, Hanh Khuu, MD, Carol Boss, A.John Barrett, MD, FRCP

Blood (2009) 114 (22): 515.

https://doi.org/10.1182/blood.V114.22.515.515

Published: 2009

Journal Articles

Haploidentical Stem Cell Transplantation: High Doses of Alloreactive-T Cell Depleted Donor Lymphocytes Administered Post-Transplant Decrease Infections and Improve Survival without Causing Severe Gvhd.

Denis-Claude Roy, MD, Silvy Lachance, MD, Thomas Kiss, MD, Sandra Cohen, MD, Lambert Busque, MD, Douglas Fish, MD, Guy Sauvageau, MD, PhD, Maarten Egeler, MD, Jean Roy, MD

Blood (2009) 114 (22): 512.

https://doi.org/10.1182/blood.V114.22.512.512

Published: 2009

Journal Articles

Adoptive Immunotherapy after Haploidentical Stem Cell Transplantation with T Cells Allodepleted by Photodynamic Purging

Katia Perruccio, MD, PhD, Fabiana Topini, MSc, Antonella Tosti, Tech, Alessandra Carotti, MD, Teresa Aloisi, MD, Franco Aversa, MD, Massimo F Martelli, MD, Andrea Velardi, MD

Blood (2008) 112 (11): 1157.

https://doi.org/10.1182/blood.V112.11.1157.1157

Published: 2008

Journal Articles

Selective Allodepletion by TH9402-Mediated Photosensitization Results in Early Full Donor T Cell Reconstitution in the Absence of High-Grade, Acute GvHD and Is Associated with Favorable Outcome after HLA Matched Sibling SCT for Hematologic Malignancies

Stephan Mielke, MD, Aarthi Shenoy, MD, Vicki S. Fellowes, Katayoun Rezvani, MD, PhD, Bipin N. Savani, MD, Laura Musse, Laura Wisch, Roger Kurlander, MD, Hanh Khuu, MD, Carol Boss, A. John Barrett, MD, FRCP

Blood (2008) 112 (11): 1168.

https://doi.org/10.1182/blood.V112.11.1168.1168

Published: 2008

Journal Articles

Assessment of Durability of Response in Patients with Skin Graft Versus Host Disease beyond Six Months Treatment with Extracorporeal Photopheresis: Reduction of Steroid Resistance and Evaluation of Long-Term Therapy on Survival.

Youssef Sorour, Peter C Taylor

Blood (2008) 112 (11): 2217.

https://doi.org/10.1182/blood.V112.11.2217.2217

Published: 2008

Journal Articles

A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique

Stephan Mielke, Raquel Nunes, Katayoun Rezvani, Vicki S. Fellowes, Annie Venne, Scott R. Solomon, Yong Fan, Emma Gostick, David A. Price, Christian Scotto, Elizabeth J. Read, A. John Barrett

Blood (2008) 111 (8): 4392–4402.

https://doi.org/10.1182/blood-2007-08-104471

Published: 2008

Includes: Supplemental data

Journal Articles

Successful Translation of a GMP-Based, Clinical Scale Selective Allodepletion Approach for Matched Donor-Recipient Pairs from Bench-to-Bedside.

Stephan Mielke, MD, Raquel Nunes, MD, Katayoun Rezvani, MD, PhD, Vicki S. Fellowes, Annie Venne, Scott R. Solomon, MD, Yong Fan, MD, Christian Scotto, PhD, Elizabeth J. Read, MD, A. John Barrett, MD

Blood (2007) 110 (11): 3279.

https://doi.org/10.1182/blood.V110.11.3279.3279

Published: 2007

Journal Articles

Anti-Chronic Graft Versus Host Disease Activity Though a Regulatory T Cell Dependent Mechanism after Photodynamic Therapy.

Jean-Philippe Bastien, Gorazd Krosl, Pascale Dube, Cynthia Therien, Christian Scotto, Denis-Claude Roy

Blood (2007) 110 (11): 3280.

https://doi.org/10.1182/blood.V110.11.3280.3280

Published: 2007

NARROW

Efficacy of Methoxsalen Sterile Solution in Conjunction with the Therakos ® Cellex ® Photopheresis System in Pediatric Patients with Steroid-Refractory Acute GvHD: Interim Analysis

Blockade of Yes-Associated Protein As a Novel Therapeutic Approach in Diffuse Large B-Cell Lymphoma

Vitamin K5 Is an Efficient Photosensitizer for Ultraviolet a Light Inactivation of Bacteria

Targeting T Cell Bioenergetics By Modulating P-Glycoprotein Selectively Depletes Alloreactive T Cells to Prevent Graft-Versus-Host Disease While Maintaining Antitumor Immunity

P-Glycoprotein Modulation Facilitates the Selective Inhibition of Oxidative Phosphorylation in Alloreactive T Cells to Prevent Graft-Versus-Host Disease after Hematopoietic Stem Cell Transplant

A Photosensitizer Verteporfin Has Light-Independent Anti-Leukemic Activity for Ph-Positive Acute Lymphoblastic Leukemia and Synergistically Works with Dasatinib in Vivo

Description of New More Effective Photochemotherapeutic Compounds for Improving Effectiveness of Extracorporeal Photopheresis

Vitamin K3 Is a Potential Ultraviolet Photosensitizer for Pathogen Reduction of Human Platelets and Plasma

Nanoparticles – a Novel Approach to Chronic Lymphocytic Leukemia Treatment?

Selective Depletion of T Cell Alloresponses Using a Photodepletion Strategy Preferentially Targets CD4+ T Cells.

Photodynamic Therapy (PDT)-Mediated Inhibition of the Transcription Factor Yin Yang 1 (YY1) That Regulates Resistance In Lymphoma

Selectively T Cell Depleted Allografts From HLA-Matched Sibling Donors Followed by Low-Dose Post Transplant Immunosuppression to Limit Disease Relapse In Patients with Hematological Malignancies

Allografts Selectively Photodepleted of GvHD Causing T Cells and Followed by Low-Level Immunosuppression: A Novel Method to Improve Disease Control After HLA-Matched Sibling Transplantations.

Haploidentical Stem Cell Transplantation: High Doses of Alloreactive-T Cell Depleted Donor Lymphocytes Administered Post-Transplant Decrease Infections and Improve Survival without Causing Severe Gvhd.

Adoptive Immunotherapy after Haploidentical Stem Cell Transplantation with T Cells Allodepleted by Photodynamic Purging

Selective Allodepletion by TH9402-Mediated Photosensitization Results in Early Full Donor T Cell Reconstitution in the Absence of High-Grade, Acute GvHD and Is Associated with Favorable Outcome after HLA Matched Sibling SCT for Hematologic Malignancies

Assessment of Durability of Response in Patients with Skin Graft Versus Host Disease beyond Six Months Treatment with Extracorporeal Photopheresis: Reduction of Steroid Resistance and Evaluation of Long-Term Therapy on Survival.

A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique

Successful Translation of a GMP-Based, Clinical Scale Selective Allodepletion Approach for Matched Donor-Recipient Pairs from Bench-to-Bedside.

Anti-Chronic Graft Versus Host Disease Activity Though a Regulatory T Cell Dependent Mechanism after Photodynamic Therapy.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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