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Journal Articles

A Genome-Wide CRISPR/Cas9 Knockout Screen Identifies BEND3 As a Determinant of Sensitivity to UBA1 Inhibition in Acute Myeloid Leukemia

Samir H Barghout, BSPharm, MSc, Neil MacLean, G. Wei Xu, Geethu Thomas, PhDMSc,BSc, Zachary Blatman, Rose Hurren, BSc, Aaron D Schimmer, MD PhD

Blood (2018) 132 (Supplement 1): 1350.

https://doi.org/10.1182/blood-2018-99-110406

Published: 2018

Journal Articles

Role of p38γ - NFATc4 - IL17A Pathway As a Potential Therapeutic Target in Cutaneous T Cell Lymphoma

Xu Hannah Zhang, PhD, Vu N. Ngo, PhD, Natalie Sandoval, MSc, Qi Cui, Yanhong Shi, PhD, Jasmine M. Zain, MD, Christiane Querfeld, MD PhD, Chao Guo, Xiwei Wu, PhD, Steven T. Rosen, MD

Blood (2016) 128 (22): 2725.

https://doi.org/10.1182/blood.V128.22.2725.2725

Published: 2016

Journal Articles

Targeting Deubiquitylating Enzyme USP1 in Multiple Myeloma

Deepika Sharma Das, PhD, Yan Song, PhD, Arghya Ray, PhD, Paul Richardson, MD, Dharminder Chauhan, PhD, Kenneth C Anderson, MD

Blood (2015) 126 (23): 1813.

https://doi.org/10.1182/blood.V126.23.1813.1813

Published: 2015

Journal Articles

Characterization Of Full-Length, Recombinant Amsh, USP9x, and USP1: Clinically-Relevant Deubiquitinases Involved In Hematological Malignancies

Nate Russell, Trevor Taylor, Kalindi Parmar, PhD, Alan D. D'Andrea, MD, Bradley B Brasher, Ph.D., Francesco D Melandri

Blood (2013) 122 (21): 4224.

https://doi.org/10.1182/blood.V122.21.4224.4224

Published: 2013

Journal Articles

Characterization Of In Vitro Hdm2 E3 Ubiquitin Ligase-Mediated p53 Ubiquitination

Bradley B Brasher, Ph.D., Eduardo Guillen, Ph.D., Ivan Tomasic, Carsten Schwerdtfeger, Ph.D., Francesco D Melandri

Blood (2013) 122 (21): 4903.

https://doi.org/10.1182/blood.V122.21.4903.4903

Published: 2013

Journal Articles

Molecular Defects In BRCC3 Complex, a Novel Pathogenic Pathway In MDS

Blood (2013) 122 (21): 264.

https://doi.org/10.1182/blood.V122.21.264.264

Published: 2013

Journal Articles

Deregulation of TLR2-JMJD3 Innate Immunity Signaling, Including a Rare TLR2 SNP As a Potential Somatic Mutation, in Myelodysplastic Syndromes (MDS)

Yue Wei, PhD, Rui Chen, Sophie Dimicoli, MD, PhD, Carlos E. Bueso-Ramos, MD, PhD, Donna S. Neuberg, ScD, Sherry A. Pierce, RN, BS, Hui Yang, MD, PhD., Yu Jia, Hong Zheng, Zhihong Fang, Martin Nguyen, Michael Fernandez, Sa A. Wang, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2012) 120 (21): 1700.

https://doi.org/10.1182/blood.V120.21.1700.1700

Published: 2012

Journal Articles

Degradation of TRAF6 by Bortezomib-Induced Autophagy Contributes to Cell Death in Acute Myeloid Leukemia and Myelodysplastic Syndrome

Jing Fang, MD/PhD, Lyndsey Bolanos, BSc, Garrett Rhyasen, BSc, Carmen Rigolino, BSc, Agostino Cortelezzi, MD, Esther Natalie Oliva, MD, Mariella Cuzzola, MD, Daniel T Starczynowski, PhD

Blood (2011) 118 (21): 2452.

https://doi.org/10.1182/blood.V118.21.2452.2452

Published: 2011

Journal Articles

New mechanism of X-linked anhidrotic ectodermal dysplasia with immunodeficiency: impairment of ubiquitin binding despite normal folding of NEMO protein

Marjorie Hubeau, Flora Ngadjeua, Anne Puel, Laura Israel, Jacqueline Feinberg, Maya Chrabieh, Kiran Belani, Christine Bodemer, Isabelle Fabre, Alessandro Plebani, Stéphanie Boisson-Dupuis, Capucine Picard, Alain Fischer, Alain Israel, Laurent Abel, Michel Veron, Jean-Laurent Casanova, Fabrice Agou, Jacinta Bustamante

Blood (2011) 118 (4): 926–935.

https://doi.org/10.1182/blood-2010-10-315234

Published: 2011

Includes: Supplemental data

Journal Articles

Improved Outcome with Total Therapy 3 (TT3) In Comparison with Total Therapy 2 (TT2) Can Be Traced to GEP70-Defined High-Risk Disease with Trisomy of 1q21 and Modest but Not Marked Hyper-Activation of the Proteasome Gene PSMD4

John Shaughnessy, Jr., PhD, Pingping Qu, Erming Tian, Bijay Nair, MD, MPH, Sarah Waheed, MD, Yazan Alsayed, MD, Frits van Rhee, MD, PhD, John Crowley, PhD, Bart Barlogie, MD, PhD

Blood (2010) 116 (21): 303.

https://doi.org/10.1182/blood.V116.21.303.303

Published: 2010

Journal Articles

Xanthohumol: A New Potential Proteasome Inhibitor That Activates the Pro-Apoptotic Arm of the Unfolded Protein Response in B-CLL Cells.

Sofie Lust, Barbara VanHoecke, PhD, Mireille Van Gele, PhD, Jerina Boelens, MD, Jan Philippé, MD PhD, Petra Vincken, Marc Bracke, MD PhD, Martine Poelman, MD, Fritz Offner, MDPhD

Blood (2007) 110 (11): 4694.

https://doi.org/10.1182/blood.V110.11.4694.4694

Published: 2007

Journal Articles

E3 Ubiquitin Ligase Rnf41 (FLRF/Nrdp1) Regulates Steady-State Cytokine Receptor Levels in Multipotent Hematopoietic Progenitors.

Xin Jing, MD, PhD, Luis Dabul, B.Sc., Laila O. Mnayer, Ph.D, Roland Jurecic, Ph.D.

Blood (2004) 104 (11): 461.

https://doi.org/10.1182/blood.V104.11.461.461

Published: 2004

Journal Articles

NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma

Laurence Catley, Ellen Weisberg, Yu-Tzu Tai, Peter Atadja, Stacy Remiszewski, Teru Hideshima, Nicholas Mitsiades, Reshma Shringarpure, Richard LeBlanc, Dharminder Chauhan, Nikhil C. Munshi, Robert Schlossman, Paul Richardson, James Griffin, Kenneth C. Anderson

Blood (2003) 102 (7): 2615–2622.

https://doi.org/10.1182/blood-2003-01-0233

Published: 2003

NARROW

A Genome-Wide CRISPR/Cas9 Knockout Screen Identifies BEND3 As a Determinant of Sensitivity to UBA1 Inhibition in Acute Myeloid Leukemia

Role of p38γ - NFATc4 - IL17A Pathway As a Potential Therapeutic Target in Cutaneous T Cell Lymphoma

Targeting Deubiquitylating Enzyme USP1 in Multiple Myeloma

Characterization Of Full-Length, Recombinant Amsh, USP9x, and USP1: Clinically-Relevant Deubiquitinases Involved In Hematological Malignancies

Characterization Of In Vitro Hdm2 E3 Ubiquitin Ligase-Mediated p53 Ubiquitination

Molecular Defects In BRCC3 Complex, a Novel Pathogenic Pathway In MDS

Deregulation of TLR2-JMJD3 Innate Immunity Signaling, Including a Rare TLR2 SNP As a Potential Somatic Mutation, in Myelodysplastic Syndromes (MDS)

Degradation of TRAF6 by Bortezomib-Induced Autophagy Contributes to Cell Death in Acute Myeloid Leukemia and Myelodysplastic Syndrome

New mechanism of X-linked anhidrotic ectodermal dysplasia with immunodeficiency: impairment of ubiquitin binding despite normal folding of NEMO protein

Improved Outcome with Total Therapy 3 (TT3) In Comparison with Total Therapy 2 (TT2) Can Be Traced to GEP70-Defined High-Risk Disease with Trisomy of 1q21 and Modest but Not Marked Hyper-Activation of the Proteasome Gene PSMD4

Xanthohumol: A New Potential Proteasome Inhibitor That Activates the Pro-Apoptotic Arm of the Unfolded Protein Response in B-CLL Cells.

E3 Ubiquitin Ligase Rnf41 (FLRF/Nrdp1) Regulates Steady-State Cytokine Receptor Levels in Multipotent Hematopoietic Progenitors.

NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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