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Journal Articles

Epigenetic Activation of the pH Regulator MCT4 in Acute Myeloid Leukemia Exploits a Fundamental Metabolic Process of Enhancing Cell Growth through Proton Shifting

Cheuk-Him Man, David T. Scadden, MD, Francois Mercier, MD FRCPC, Nian Liu, Wentao Dong, Gregory Stephanopoulos, PhD, Li Jiang, PhD, Yookyung Jung, PhD, Charles Lin, PhD, Anskar Y.-H. Leung, MD PhD

Blood (2019) 134 (Supplement_1): 3765.

https://doi.org/10.1182/blood-2019-123604

Published: 2019

Journal Articles

The Frequency of Calr and MPL Gene Mutations in Jak2 V617F - Positive Chronic Myeloproliferative Neoplasms in Russia

Tatiana V Makarik, PhD, Adhamjon O Abdullaev, MD PhD, Sergei M. Kulikov, PhD, Elena E Nikulina, Svetlana A Treglazova, Irina N Subortseva, MD, Alla M. Kovrigina, MD PhD, Anait L. Melikyan, MD PhD, Andrey B Sudarikov, PhD DSc, Valery G. Savchenko, MD PhD academician

Blood (2019) 134 (Supplement_1): 5400.

https://doi.org/10.1182/blood-2019-124767

Published: 2019

Journal Articles

Dimethyl Oxalyl Glycine a Prolyl Hydroxylase Inhibitor Decreases Early Gastrointestinal Gvhd Via Two Independent Pathways of Apoptosis after Allogeneic Hematopoietic Cell Transplantation

Reena Kumari, PhD, Senthilnathan Palaniyandi, PhD, Ethan Strattan, BS, Sabarinath Venniyil Radhakrishnan, MBBS, MD, Gerhard Carl Hildebrandt, MD

Blood (2018) 132 (Supplement 1): 3317.

https://doi.org/10.1182/blood-2018-99-116245

Published: 2018

Journal Articles

The Use of Imatinib with Chemotherapy and Allogeneic Hematopoietic Stem Cell Transplantation Improves Survival of Philadelphia Positive Acute Lymphoblastic Leukemia in Adults

Josefina Perez-Nuñez, MD, Antonio Jimenez-Velasco, MD, Katy Hurst, MD, Manuel Barrios-Garcia, MD PhD, MJ Moreno, MD, Ana Isabel Heiniger Mazo, MD

Blood (2014) 124 (21): 3653.

https://doi.org/10.1182/blood.V124.21.3653.3653

Published: 2014

Journal Articles

Inhibition of NHE1 Induced Apoptosis in Cytarabine Resistant Leukemia Cell Lines and Primary Leukemia Cells from AML Patients, Which Showed Increased Intracellular pH and NHE1 Activity

Shin Young Hyun, Young Kyung Kim, Ji Eun Jang, MD, Yundeok Kim, MD, Yu Ri Kim, MD PhD, June-Won Cheong, MD,PhD, Kwang Yong Shim, Yoo Hong Min, MD,PhD

Blood (2014) 124 (21): 3614.

https://doi.org/10.1182/blood.V124.21.3614.3614

Published: 2014

Journal Articles

Palmitic Acid, As Verified Using Lipid Profiling By Secondary Ion Mass Spectrometry, Demonstrates Anti-Tumor Activity Against Multiple Myeloma

Yasuyuki Nagata, MD, Itsuko Ishizaki, Michihiko Waki, Yoshimi Ide, MD PhD, Md Amir Hossen, Kazunori Ohnishi, MD PhD, Mitsutoshi Setou, MD PhD

Blood (2014) 124 (21): 5683.

https://doi.org/10.1182/blood.V124.21.5683.5683

Published: 2014

Journal Articles

Novel Therapeutic Strategy Targeting NHE1 and Its Upstream Activators in Acute Myeloid Leukemia

Cheuk-Him Man, PhD, Chae-Yin Cher, Stephen S.Y. Lam, Eric S.K. Ho, Nelson K.L. Ng, Anskar Y.H. Leung, MD

Blood (2014) 124 (21): 913.

https://doi.org/10.1182/blood.V124.21.913.913

Published: 2014

Journal Articles

Carfilzomib PLUS Melphalan and Prednisone (CMP) Is A Promising Combination Therapy For The Treatment Of Elderly Patients With NEWLY Diagnosed Multiple Myeloma: Results Of A PHASE I/II Trial In 68 CASES

Philippe Moreau, MD, Brigitte Kolb, MD, Cyrille Hulin, MD, Denis Caillot, MD, Lotfi Benboubker, MD, Mourad Tiab, MD, Cyrille Touzeau, Xavier Leleu, MD, PhD, Murielle Roussel, MD, Carine Chaleteix, MD, Michel Attal, MD, Thierry Facon, MD

Blood (2013) 122 (21): 1933.

https://doi.org/10.1182/blood.V122.21.1933.1933

Published: 2013

Journal Articles

The Prolyl Hydroxylase Inhibitor Dimethyl Oxalyl Glycine Decreases the Severity of Acute Lung Injury After Allogeneic Hematopoietic Cell Transplantation.

Sabarinath Venniyil Radhakrishnan, MD, Senthilnathan Palaniyandi, PhD, Fridrik Karlsson, PhD, Elisabeth Huber, MD, Gerhard Hildebrandt, MD

Blood (2012) 120 (21): 3006.

https://doi.org/10.1182/blood.V120.21.3006.3006

Published: 2012

Journal Articles

Pharmacologic Doses of Amiloride Preferentially Induce Apoptosis and Growth Inhibition of Flt3-ITD Mutation Positive Acute Myeloid Leukemia Cell Lines

Yuliya Linhares, M.D., Jade Dardine, M.D., Siavash Kurdistani, M.D.

Blood (2011) 118 (21): 5004.

https://doi.org/10.1182/blood.V118.21.5004.5004

Published: 2011

Journal Articles

The Prognosis of Children Acute Lymphoblastic Leukemia (ALL) with Minimal Residual Disease (MRD) ≥10-2 After Induction (TP1) Depends on the Prephase Response and on the Level of the MRD After Consolidation (TP2): Results of the 58951EORTC Trial

Yves Bertrand, Stefan Suciu, Nathalie Grardel, Marleen Bakkus, PhD, Francoise Mazingue, MD, Karima Yacouben, Anne Uyttebroeck, Patrick Lutz, Dominique Plantaz, Sandrine Girard, Nicole Dastugue, Yves Benoit, MD, Hélène Cavé

Blood (2011) 118 (21): 2571.

https://doi.org/10.1182/blood.V118.21.2571.2571

Published: 2011

Journal Articles

Intensification of Chemotherapeutic Regimens and Hematopoietic Stem Cell Transplantation Are Responsible for Improved Overall Survival in Adult Acute Lymphoblastic Leukemia in a Single Center Over the Last Forty Years

Estrella Carrillo, MD, Nancy Rodriguez, Juan Francisco Dominguez, Jose Gonzalez, MD, Jose Francisco Falantes, MD, Isabel Montero, MD, M. Luz Martino, MD, Francisco Márquez-Malaver, Ricardo Parody, MD, Estefania Garcia-Guerrero, Jose Antonio Perez-Simón, Sr., MD, PhD, Ildefonso Espigado, MD, PhD

Blood (2011) 118 (21): 4227.

https://doi.org/10.1182/blood.V118.21.4227.4227

Published: 2011

Journal Articles

Stress Erythropoiesis: HIF-1 Alpha Synergizes with Glucocorticoids to Induce BFU-E Progenitor Self-Renewal

Johan Flygare, MD, PhD, Violeta Rayon Estrada, Chanseok Shin, PhD, Sumeet Gupta, Harvey Lodish

Blood (2010) 116 (21): 814.

https://doi.org/10.1182/blood.V116.21.814.814

Published: 2010

Journal Articles

The Utility of Bone Marrow Examinations for the Diagnosis of Immune Thrombocytopenia.

Vishwanath Kishan Mahabir, MD, Cathy Ross, MD, Snezana Popovic, MD, Jacqueline Bourgeois, MD, Grace Wang, James N. George, MD, Wendy Lim, MD, MSc, John G. Kelton, MD, FRCPC, Donald M. Arnold, MD

Blood (2010) 116 (21): 3691.

https://doi.org/10.1182/blood.V116.21.3691.3691

Published: 2010

Journal Articles

A Mechanism Based Pharmacokinetic/Pharmacodynamic Model of the Effect of a Prolyl Hydroxylase Inhibitor on Erythropoietic Response In Mice

Indrajeet Singh, Wojciech Krzyzanski, Pratap Singh

Blood (2010) 116 (21): 4769.

https://doi.org/10.1182/blood.V116.21.4769.4769

Published: 2010

Journal Articles

Association Study of Ploidy Category with Mitotic Disruption In Multiple Myeloma

Elena Dementyeva, MD, Fedor Kryukov, MD, Sabina Sevcikova, PhD, Pavel Nemec, Smetana Jan, Henrieta Greslikova, Romana Zaoralova, Ivana Buresova, Miroslav Penka, MD, PhD, Petr Kuglik, PhD, Roman Hajek, MD, PhD

Blood (2010) 116 (21): 2952.

https://doi.org/10.1182/blood.V116.21.2952.2952

Published: 2010

Journal Articles

Adjudicating Bleeding Outcomes in a Large Thromboprophylaxis Trial in Critical Illness.

Donald M. Arnold, MDCM, MSc, Christian Rabbat, MD, Francois Lauzier, MD, Nicole Zytaruk, Diane Heels-Ansdell, Deborah Cook, MD, MSc

Blood (2009) 114 (22): 2471.

https://doi.org/10.1182/blood.V114.22.2471.2471

Published: 2009

Journal Articles

Elevated Circulating Platelet-Derived Microparticles in Ph1 Negative Chronic Myeloproliferative Disorders.

Véronique Tintillier-Colin, Nathalie Cambier, MD, Emmanuelle Bourgeois-Petit, MD, Christian Rose, MD, Gérard Forzy, MD, Jean-Loup Demory, MD, Agnès Charpentier, MD

Blood (2009) 114 (22): 1906.

https://doi.org/10.1182/blood.V114.22.1906.1906

Published: 2009

Journal Articles

A Multifaceted Strategy to Reduce Inappropriate Use of Fresh Frozen Plasma Transfusions in the Intensive Care Unit.

Donald M. Arnold, MDCM, MSc, Heather Whittingham, MD, Francois Lauzier, France Clarke, Ellen McDonald, Andrea Tkaczyk, Angela Greiter, Lily Waugh, Mark A. Crowther, MD, Deborah Cook

Blood (2009) 114 (22): 1412.

https://doi.org/10.1182/blood.V114.22.1412.1412

Published: 2009

Journal Articles

Adherence to Imatinib Mesylate Treatment: Two Years Follow up

Carlos A. Doti, M.D., German R Stemmelin, M.D., Elena Beatriz Moiraghi, MD, María Gabriela Flores, MD, Juan Garcia, MD, Hector Murro, MD, Eduardo O Bullorsky

Blood (2008) 112 (11): 4267.

https://doi.org/10.1182/blood.V112.11.4267.4267

Published: 2008

NARROW

Epigenetic Activation of the pH Regulator MCT4 in Acute Myeloid Leukemia Exploits a Fundamental Metabolic Process of Enhancing Cell Growth through Proton Shifting

The Frequency of Calr and MPL Gene Mutations in Jak2 V617F - Positive Chronic Myeloproliferative Neoplasms in Russia

Dimethyl Oxalyl Glycine a Prolyl Hydroxylase Inhibitor Decreases Early Gastrointestinal Gvhd Via Two Independent Pathways of Apoptosis after Allogeneic Hematopoietic Cell Transplantation

The Use of Imatinib with Chemotherapy and Allogeneic Hematopoietic Stem Cell Transplantation Improves Survival of Philadelphia Positive Acute Lymphoblastic Leukemia in Adults

Inhibition of NHE1 Induced Apoptosis in Cytarabine Resistant Leukemia Cell Lines and Primary Leukemia Cells from AML Patients, Which Showed Increased Intracellular pH and NHE1 Activity

Palmitic Acid, As Verified Using Lipid Profiling By Secondary Ion Mass Spectrometry, Demonstrates Anti-Tumor Activity Against Multiple Myeloma

Novel Therapeutic Strategy Targeting NHE1 and Its Upstream Activators in Acute Myeloid Leukemia

Carfilzomib PLUS Melphalan and Prednisone (CMP) Is A Promising Combination Therapy For The Treatment Of Elderly Patients With NEWLY Diagnosed Multiple Myeloma: Results Of A PHASE I/II Trial In 68 CASES

The Prolyl Hydroxylase Inhibitor Dimethyl Oxalyl Glycine Decreases the Severity of Acute Lung Injury After Allogeneic Hematopoietic Cell Transplantation.

Pharmacologic Doses of Amiloride Preferentially Induce Apoptosis and Growth Inhibition of Flt3-ITD Mutation Positive Acute Myeloid Leukemia Cell Lines

The Prognosis of Children Acute Lymphoblastic Leukemia (ALL) with Minimal Residual Disease (MRD) ≥10-2 After Induction (TP1) Depends on the Prephase Response and on the Level of the MRD After Consolidation (TP2): Results of the 58951EORTC Trial

Intensification of Chemotherapeutic Regimens and Hematopoietic Stem Cell Transplantation Are Responsible for Improved Overall Survival in Adult Acute Lymphoblastic Leukemia in a Single Center Over the Last Forty Years

Stress Erythropoiesis: HIF-1 Alpha Synergizes with Glucocorticoids to Induce BFU-E Progenitor Self-Renewal

The Utility of Bone Marrow Examinations for the Diagnosis of Immune Thrombocytopenia.

A Mechanism Based Pharmacokinetic/Pharmacodynamic Model of the Effect of a Prolyl Hydroxylase Inhibitor on Erythropoietic Response In Mice

Association Study of Ploidy Category with Mitotic Disruption In Multiple Myeloma

Adjudicating Bleeding Outcomes in a Large Thromboprophylaxis Trial in Critical Illness.

Elevated Circulating Platelet-Derived Microparticles in Ph1 Negative Chronic Myeloproliferative Disorders.

A Multifaceted Strategy to Reduce Inappropriate Use of Fresh Frozen Plasma Transfusions in the Intensive Care Unit.

Adherence to Imatinib Mesylate Treatment: Two Years Follow up

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American Society of Hematology

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American Society of Hematology

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