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Journal Articles

Microenvironmental Signatures Reveal Biological Subtypes of Diffuse Large B-Cell Lymphoma (DLBCL) Distinct from Tumor Cell Molecular Profiling

Leandro Cerchietti, MD, Giorgio Inghirami, MD, Nikita Kotlov, PhD, Viktor Svekolkin, PhD, Alexander Bagaev, PhD, Felix Frenkel, PhD, Maria Victoria Revuelta, PhD, Jude M Phillip, PhD, Maria Teresa Cacciapuoti, MS, Sarah C. Rutherford, MD, Peter Martin, FRCPC, MD MS, John P. Leonard, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 656.
https://doi.org/10.1182/blood-2019-128889
Published: 2019
Journal Articles

A Novel Targeted Approach to Achieve Immune System Reset: CD45-Targeted Antibody Drug Conjugates Enable Autologous HSCT, Ameliorate Disease in Autoimmune Models, Potently Kill Human Immune Cells from Normal Donors and MS Patients, and Achieve Immune Depletion in Non-Human Primates (NHP)

Geoff O Gillard, Jennifer L Proctor, BS, Melissa L. Brooks, BS, Tahirih L Lamothe, BS, Sharon L. Hyzy, MS, Oliver Mikse, Sean McDonough, Rahul Palchaudhuri, PhD, Anjali Bhat, MS, Ganapathy N. Sarma, PhD, Prashant Bhattarai, Pranoti Sawant, MS, Bradley R Pearse, PhD, Charlotte F. Mcdonough, PhD, Anthony E. Boitano, PhD, Michael P. Cooke, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3208.
https://doi.org/10.1182/blood-2019-130752
Published: 2019
Journal Articles

Versican Proteolytic Fragments (Matrikines) Regulate the Intratumoral Dendritic Cell Milieu In Vivo: Implications for in Situ Tumor Vaccination

Athanasios Papadas, MD, Evan Flietner, BS, Zachary Morrow, BS, Joshua Wiesner, Alexander Cicala, Adam Pagenkopf, BS, Chelsea L. Hope, PhD, Adhithi Rajagopalan, BS, Zhi Wen, PhD, Philip Emmerich, Dustin Deming, Shigeki Miyamoto, PhD, Peiman Hematti, MD, Natalie Scott Callander, MD, Alexander Rakhmilevich, Mario Otto, MD PhD, Christian M. Capitini, MD, Jing Zhang, PhD, Fotis Asimakopoulos, PhDMBBChir,
Journal: Blood
Blood (2019) 134 (Supplement_1): 1210.
https://doi.org/10.1182/blood-2019-131582
Published: 2019
Journal Articles

Syndecan-1 Is Critical in ARF6-Dependent Macropinocytosis Driven By KRAS Mutation in the Pathophysiology of Multiple Myeloma

Tengteng Yu, MD PhD, Liang Lin, PhD, Kenneth Wen, Lijie Xing, MD, Jiye Liu, PhD, Shih-Feng Cho, MD PhD, Phillip Hsieh, Ola Rizq, MD PhD, Yuyin Li, PhD, Liang Yu, Xiang Wu, Eugenio Morelli, MD, Yan Xu, MD, Gang An, MD, Nikhil C. Munshi, MD, Lugui Qiu, MD PhD, Kenneth C. Anderson, MD, Yu-Tzu Tai, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4371.
https://doi.org/10.1182/blood-2019-127454
Published: 2019
Journal Articles

Preliminary Phase 1 Data on the Safety and Efficacy of a Novel PET Radiotracer, 124 I-p5+14, for Imaging Systemic Amyloidosis

Jonathan S. Wall, PhD, Alan Stuckey, Emily B. Martin, PhD, Tina Richey, MS, Angela Williams, MS, Daniel Craig Wooliver, Sallie Macy, James S. Foster, MS, Bryan Whittle, Robin Geldrich, Mark Powell, Yitong Fu, MD, Dustin Powell, MD, Dustin Osborne, PhD, R. Eric Heidel, PhD, Barbara Marine, Myrwood Besozzi, MD, Radhakrishnan Ramchandren, MD, Ronald H. Lands, MD, Stephen J. Kennel, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3034.
https://doi.org/10.1182/blood-2019-128850
Published: 2019
Journal Articles

Versican (VCAN) Proteolysis Predicts Survival in Multiple Myeloma (MM) after High Dose Therapy and Autologous Hematopoietic Cell Transplantation (HDT/AHCT)

Binod Dhakal, MBBS, Muhammad Umair Mushtaq, MD, Ashley Cunningham, MD, Athanasios Papadas, MD, Adam Pagenkopf, BS, Joshua Wiesner, Catherine Leith, MBBChir, Peiman Hematti, MD, Parameswaran Hari, MBBS, MD, Natalie Scott Callander, MD, Fotis Asimakopoulos, PhDMBBChir,
Journal: Blood
Blood (2019) 134 (Supplement_1): 3088.
https://doi.org/10.1182/blood-2019-127565
Published: 2019
Journal Articles

Genomic Landscape of Sex Disparities in Multiple Myeloma

Susan Bal, MDMBBS, Kwangmin Choi, PhD, Omer Jamy, MD, Saulius K. Girnius, MD, Heather J Landau, MD, Luciano J. Costa, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3067.
https://doi.org/10.1182/blood-2019-127429
Published: 2019
Journal Articles

Hemostatic Activation and Glycocalyx Shedding during Pregnancy

Maria Cristina Bravo, PhD, Ira Bernstein, MD, Carole McBride, PhD, Elizabeth McGee, MD, Kelley C. McLean, MD, Thomas Orfeo, PhD, Kathleen E. Brummel-Ziedins, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3794.
https://doi.org/10.1182/blood-2018-99-119304
Published: 2018
Journal Articles

Tissue Factor Pathway Inhibitor Enhances Transendothelial Migration of Chronic Lymphocytic Leukemia Cells through Binding to Glypican-3

Xueyan Cui, MD PhD, Geir Erland Tjønnfjord, MD DMsc, Sandip Kanse, PhD, Nina Iversen, PhD, Anders EA Dahm, MD PhD, Christiane Filion Myklebust, Ling Sun, MD PhD, Zhong Xing Jiang, MD PhD, Mitchell Ho, PhD, Per Morten Sandset
Journal: Blood
Blood (2018) 132 (Supplement 1): 2452.
https://doi.org/10.1182/blood-2018-99-111241
Published: 2018
Journal Articles

Identification of Syndecan-1 As a Key Dependency of Myeloid Leukemia Growth and Dissemination

Kyle Spinler, BS, DPhil, Tannishtha Reya, PhD, Jeevisha Bajaj, PhD, Takahiro Ito, Bryan Zimdahl, PhD, Armin Ahmadi, BS, Claire Koechlein, Nikki Lytle, Hyog Young Kwon, PhD, Ferdous Anower-E-Khuda, PhD, Marcie Kritzik, Jan Karlseder, Pyong Woo Park, PhD, Jeffrey Esko, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3003.
https://doi.org/10.1182/blood-2018-99-115199
Published: 2018
Journal Articles

Osteoblastic Cell-Derived Extracellular Vesicles Transfer Small RNAs That Alter the Physiology of Hematopoietic Cells In Vivo

Youmna Kfoury, PhD, Anthony Anselmo, PhD, Jefferson Seidl, BA, Ani Papazian, BS, Francois Mercier, MD FRCPC, David B Sykes, MD PhD, Nicolas Severe, PhD, Borja Saez, PhD, Ruslan I Sadreyev, PhD, David T. Scadden, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 93.
https://doi.org/10.1182/blood.V130.Suppl_1.93.93
Published: 2017
Journal Articles

Versican (VCAN) Proteolysis Predicts T-Cell Infiltration in Myeloma Bone Marrow Post- Autologous Stem Cell Transplant (ASCT)

Adam Pagenkopf, Binod Dhakal, MBBS, Chelsea L. Hope, PhD, Athanasios Papadas, MD, Michael G Johnson, PhD, Bradley Nagel, Elena Kurudza, Samik Partha, Bianca Ruffolo, Catherine Leith, MBBChir, Shigeki Miyamoto, PhD, Peiman Hematti, MD, Parameswaran Hari, MD MRCP, MS, Natalie Scott Callander, MD, Fotios Asimakopoulos, PhDMBBChir,
Journal: Blood
Blood (2017) 130 (Supplement 1): 1756.
https://doi.org/10.1182/blood.V130.Suppl_1.1756.1756
Published: 2017
Journal Articles

GWAS Meta-Analysis of Glomerular Filtration Rate in Three Cohorts of Sickle Cell Disease Patients and In Vivo Functional Analysis Reveals Potential Nephropathy Candidate Genes

Blair R. Anderson, BS, Melanie E. Garrett, MS, Karen L. Soldano, BS, Eugene P. Orringer, MD, James R. Eckman, MD, Ludmila Francescatto, PhD, Erica E. Davis, PhD, Mark T. Gladwin, MD, Victor R. Gordeuk, MD, Marilyn J. Telen, MD, Allison E. Ashley-Koch, PhD
Journal: Blood
Blood (2016) 128 (22): 269.
https://doi.org/10.1182/blood.V128.22.269.269
Published: 2016
Journal Articles

Platelet Factor 4 Induces Leukocyte Responses through Integrin Mac-1 (CD11b/CD18)

Nataly P. Podolnikova, PhD, Valentin P. Yakubenko, PhD, Tatiana P. Ugarova, PhD
Journal: Blood
Blood (2016) 128 (22): 2529.
https://doi.org/10.1182/blood.V128.22.2529.2529
Published: 2016
Journal Articles

EPCR Guides Hematopoietic Stem Cells Homing to the Bone Marrow Independently of Niche Clearance

Shiri Gur-Cohen, PhD, Francesca Avemaria, PhD, Orit Kollet, PhD, Seymen Avci, MSc, Tomer Itkin, PhD, Saravana K. Ramasamy, PhD, Anjali P. Kusumbe, PhD, Karin Golan, PhD, Eman Khatib-Massalha, Msc, Anju Kumari, PhD, Mayela M. Carolina, PhD, Wei-Ling Lin, PhD, Qing-Cissy Yu, PhD, Hua-Lin Wu, PhD, Yi Arial Zeng, PhD, Ralf H. Adams, PhD, Conway M. Edward, PhD, Elizabeth J. Shpall, MD, Ayelet Erez, PhD, Irit Sagi, PhD, Charles T. Esmon, PhD, Wolfram Ruf, MD, Tsvee Lapidot, PhD
Journal: Blood
Blood (2016) 128 (22): 4538.
https://doi.org/10.1182/blood.V128.22.4538.4538
Published: 2016
Journal Articles

Versican vs versikine: tolerance vs attack

Michael Schmitt
Journal: Blood
Blood (2016) 128 (5): 612–613.
https://doi.org/10.1182/blood-2016-06-721092
Published: 2016
Journal Articles

Immunoregulatory roles of versican proteolysis in the myeloma microenvironment

Brief Report
Chelsea Hope, Simon Foulcer, Justin Jagodinsky, Sarah X. Chen, Jeffrey L. Jensen, Sanjay Patel, Catherine Leith, Ioanna Maroulakou, Natalie Callander, Shigeki Miyamoto, Peiman Hematti, Suneel S. Apte, Fotis Asimakopoulos
Journal: Blood
Blood (2016) 128 (5): 680–685.
https://doi.org/10.1182/blood-2016-03-705780
Published: 2016
Includes: Supplemental data
Journal Articles

Biomarkers of Hemostatic Dysregulation, Inflammation, and Infection in Patients Diagnosed with Sepsis Associated Coagulopathy

Amanda Walborn, Daniel Kahn, Debra Hoppensteadt, PhD, Jawed Fareed, PhD
Journal: Blood
Blood (2015) 126 (23): 2281.
https://doi.org/10.1182/blood.V126.23.2281.2281
Published: 2015
Journal Articles

Roneparstat (SST0001), an Innovative Heparanase (HPSE) Inhibitor for Multiple Myeloma (MM) Therapy: First in Man Study

Monica Galli, MD, Hila Magen, MD, Hermann Einsele, Manik Chatterjee, MD, Mariella Grasso, MD, Giorgina Specchia, Paola Barbieri, MD, David Paoletti, MS, Silvia Pace, MS, Ralph D Sanderson, PhD, Alessandro Rambaldi, MD, Arnon Nagler, MD MSc
Journal: Blood
Blood (2015) 126 (23): 3246.
https://doi.org/10.1182/blood.V126.23.3246.3246
Published: 2015
Journal Articles

IL-1β, in contrast to TNFα, is pivotal in blood-induced cartilage damage and is a potential target for therapy

Lize F. D. van Vulpen, Roger E. G. Schutgens, Katja Coeleveld, Els C. Alsema, Goris Roosendaal, Simon C. Mastbergen, Floris P. J. G. Lafeber
Journal: Blood
Blood (2015) 126 (19): 2239–2246.
https://doi.org/10.1182/blood-2015-03-635524
Published: 2015