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Journal Articles

HTLV-1 Dysregulates IL-6 and IL-10-JAK/STAT Signaling and Induces Leukemia/Lymphoma of Mature CD4+ T Cells with Regulatory T-Cell-like Signatures

Yusuke Higuchi, MD, Jun-ichirou Yasunaga, MD PhD, Yu Mitagami, PhD, Koichi Ohshima, MD PhD, Masao Matsuoka, MD PhD

Blood (2019) 134 (Supplement_1): 1516.

https://doi.org/10.1182/blood-2019-125546

Published: 2019

Journal Articles

The Presence and Possible Role of Virus-Host Chimeric Transcripts in Adult T-Cell Leukemia-Lymphoma

Hiroo Katsuya, MD, Paola Miyazato, PhD, Saiful Islam, Benjy Jek Yang Tan, MD, Yuki Inada, Misaki Matsuo, Takaharu Ueno, Masahito Tokunaga, MD PhD, Hiroyuki Hata, MD PhD, Makoto Yamagishi, PhD, Jun-Ichi Fujisawa, Toshiki Watanabe, MD, PhD, Kaoru Uchimaru, MD, PhD, Atae Utsunomiya, MD, Shinya Kimura, MD PhD, Yorifumi Satou, MD PhD

Blood (2019) 134 (Supplement_1): 2779.

https://doi.org/10.1182/blood-2019-124361

Published: 2019

Journal Articles

Dynamic Changes of Chromatin Structure and Transcriptome By Transient Expression of HTLV-1 Tax in ATL Cells

Daisuke Kurita, MD PhD, Jun-ichirou Yasunaga, MD PhD, Azusa Tanaka, PhD, Mahgoub Mohamed, MD PhD, Masao Matsuoka, MD PhD

Blood (2018) 132 (Supplement 1): 4094.

https://doi.org/10.1182/blood-2018-99-111125

Published: 2018

Journal Articles

Genetic Evidence for Involvement of Human Endogenous Retrovirus Herv-Fc1 in the Pathogenesis of MPNs

Vibe Skov, PhD, Katrine LM Schmidt, Kasper Mønsted Pedersen, MD, Bettina Hansen, Tobias Wirenfeldt Klausen, M.S., Torben A Kruse, Mads Thomassen, PhD, Lasse Kjær, PhD, Christina Ellervik, Associate Professor, MD PhD, Morten Holmstrøm, MD, Bjørn Nexø, Hans Carl Hasselbalch, Professor, dr.MD, Magdalena J Laska

Blood (2018) 132 (Supplement 1): 5488.

https://doi.org/10.1182/blood-2018-99-118080

Published: 2018

Journal Articles

The In Vivo infected Clones Have Mixed Immunophenotype and Malignant Transformation Is Characterized By Dominant Growth of CD4+CCR4+CD26-CD7- Cells in Human T Lymphotropic Virus Type 1 Infection

Huseini Hatimbhai Kagdi, MD PhD MBBS, FRCPath, MRCP, Graham Phillip Taylor, MB ChB, DSc, FRCP, FHEA

Blood (2018) 132 (Supplement 1): 2844.

https://doi.org/10.1182/blood-2018-99-111440

Published: 2018

Journal Articles

Histone Deacetylase Inhibitors Abolish HBZ Protein Expression and Induce Cell Death in HTLV-1 Related Adult T-Cell Leukemia-Lymphoma

Ngoc L Toomey, BS, Juan Carlos Ramos, MD BS

Blood (2017) 130 (Supplement 1): 4012.

https://doi.org/10.1182/blood.V130.Suppl_1.4012.4012

Published: 2017

Journal Articles

Clonal Tracking of the Source of Red Cell and Platelet Production in Rhesus Macaques

Xing Fan, MD, Chuanfeng Wu, MD, Diego Espinoza, Stephanie Sellers, Aylin Bonifacino, MS, Robert E Donahue, VMD, Luca Schifanella, Genoveffa Franchini, Cynthia E Dunbar, MD

Blood (2017) 130 (Supplement 1): 932.

https://doi.org/10.1182/blood.V130.Suppl_1.932.932

Published: 2017

Journal Articles

Highly Sensitive Viral RNA-Seq Is a Powerful Tool to Analyze the Viral Transcripts in HTLV-1-Infected Individuals

Yuki Inada, Hiroo Katsuya, MD, Paola Miyazato, PhD, Benjy Jek Yang Tan, MD, Saori Iwase, Misaki Kakoki, Misaki Matsuo, Saiful Islam, Masahito Tokunaga, MD, Hiroyuki Hata, MDPhD, Yoshihisa Yamano, MD, Atae Utsunomiya, MD, Yorifumi Satou, MD PhD

Blood (2017) 130 (Supplement 1): 2484.

https://doi.org/10.1182/blood.V130.Suppl_1.2484.2484

Published: 2017

Journal Articles

A Descriptive Study of Viral RNA Sequences Identified from Single-Cell Analysis of Acute Myeloid Leukemia

Sharah Mae Capinpin, Chunkiat Lee, Ming Xuan Lin, Gabriel Yan, Dr, Kenneth Ban, Dr, Tin Wee Tan, Prof, Roger Foo, Assoc Prof, Wee Joo Chng, MB ChB, MRCP, PhD, Benedict Yan, Dr

Blood (2017) 130 (Supplement 1): 5091.

https://doi.org/10.1182/blood.V130.Suppl_1.5091.5091

Published: 2017

Journal Articles

Dual-Method Clone Tracking in Nonhuman Primates Confirms Long-Term Hematopoietic Reconstitution Initiated By Early Engrafting Clones

Jennifer E Adair, PhD, Zachary K. Norgaard, MSc, Kevin G Haworth, PhD, Lauren E Schefter, BA, Kenric Tam, MD, Matthew Porteus, MD PhD, Hans-Peter Kiem, MD FACP

Blood (2016) 128 (22): 1475.

https://doi.org/10.1182/blood.V128.22.1475.1475

Published: 2016

Journal Articles

Monitoring of Adult T-Cell Leukemia-Lymphoma Cells in Patients Receiving Mogamulizumab, a Humanized Anti-CCR4 Monoclonal Antibody, Using T-Cell Receptor Repertoire Analysis

Masato Saito, Takashi Ishida, MD PhD, Itaru Urakawa, PhD, Toshihiko Ishii, Asahi Ito, MD PhD, Ayako Masaki, MD PhD, Susumu Suzuki, PhD, Shigeru Kusumoto, MD PhD, Hirokazu Komatsu, MD PhD, Hiroshi Inagaki, MD PhD, Takeshi Takahashi, PhD, Ryuzo Ueda, MD PhD, Shinsuke Iida, MD PhD

Blood (2016) 128 (22): 1744.

https://doi.org/10.1182/blood.V128.22.1744.1744

Published: 2016

Journal Articles

Hematopoietic Stem Cell Infected with HTLV-1 Functions As a Viral Reservoir In Vivo

Jun-ichirou Yasunaga, MDPhD, Rie Furuta, Michi Miura, Kenji Sugata, Akatsuki Saito, Akari Hirofumi, Takaharu Ueno, Norihiro Takenouchi, Jun-ichi Fujisawa, Masakazu Shimizu, Fumihiko Matsuda, MD PhD, Anat Melamed, Charles R. M. Bangham, Masao Matsuoka, MD PhD

Blood (2016) 128 (22): 1343.

https://doi.org/10.1182/blood.V128.22.1343.1343

Published: 2016

Journal Articles

Comprehensive Integration Site Analysis of Human Immunodeficiency Virus during In Vivo Infections Reveals Genomic Regions of Enrichment and Clonal Expansion

Kevin G Haworth, PhD, Lauren E Schefter, BA, Zachary K. Norgaard, MSc, Jennifer E Adair, PhD, Hans-Peter Kiem, MD PhD

Blood (2016) 128 (22): 2518.

https://doi.org/10.1182/blood.V128.22.2518.2518

Published: 2016

Journal Articles

Intensive Chemotherapy with DA-Edoch Followed By Allogeneic Hematopoietic Stem Cell Transplantation Improved the Outcome in HTLV-1 Associated Adult T Cell Leukemia (ATL)

Jianda Hu, MD PhD, Ting Yang, Prof.,MD,PhD, Zhengjun Wu, MD, Jinghua Ren, MD, Xiaoyun Zheng, MD, Tingbo Liu, Prof.,MD,PhD, Zhizhe Chen, Prof., MD,PhD

Blood (2016) 128 (22): 5840.

https://doi.org/10.1182/blood.V128.22.5840.5840

Published: 2016

Journal Articles

New Molecular Surrogate Assay for Genotoxicity Assessment of Gene Therapy Vectors (SAGA)

Adrian Schwarzer, MD PhD, Steven R Talbot, PhD, Oliver Dittrich-Breiholz, PhD, Adrian J Thrasher, MD PhD, Bobby Gaspar, MD, Ute Modlich, Christopher Baum, MD, Axel Schambach, MD PhD, Michael Rothe, PhD

Blood (2016) 128 (22): 4710.

https://doi.org/10.1182/blood.V128.22.4710.4710

Published: 2016

Journal Articles

The Sea Urchin sns5 Chromatin Insulator Improves the Likelihood of Lentiviral Vectors in Erythroid Milieu By Organizing an Independent Chromatin Domain at the Integration Site

Elena Baiamonte, Rosalia Di Stefano, Melania Lo Iacono, Barbara Spina, Angela Vitrano, Rosario Di Maggio, Massimiliano Sacco, Giovanni Spinelli, Aurelio Maggio, Santina Acuto, Vincenzo Cavalieri

Blood (2015) 126 (23): 4414.

https://doi.org/10.1182/blood.V126.23.4414.4414

Published: 2015

Journal Articles

Activity of PIM Kinases in Chronic Lymphocytic Leukemia Modulates Tumor Cell Survival and Stromal Interactions through a Pleiotropic Mechanism Involving Modulation of CXCR4 - mTOR Pathway

Blood (2015) 126 (23): 1549.

https://doi.org/10.1182/blood.V126.23.1549.1549

Published: 2015

Journal Articles

The Combination of Belinostat with Zidovudine for Treatment of HTLV-I Related Adult T-Cell Leukemia-Lymphoma

Ngoc Toomey, Juan Carlos Ramos, MD

Blood (2015) 126 (23): 1562.

https://doi.org/10.1182/blood.V126.23.1562.1562

Published: 2015

Journal Articles

Next-Generation Sequencing Reveal Proviral Genome and Transcriptome in Adult T-Cell Leukemia/Lymphoma

Blood (2015) 126 (23): 3882.

https://doi.org/10.1182/blood.V126.23.3882.3882

Published: 2015

Journal Articles

Cytotoxic T-Lymphocyte Analysis of Aggressive Types of Adult T-Cell Leukemia/Lymphoma Patients with Complete Remission after Intensive Combination Chemotherapy

Tatsuro Jo, MD PhD, Kensuke Horio, MD, Kazuto Shigematsu, MD PhD

Blood (2014) 124 (21): 1648.

https://doi.org/10.1182/blood.V124.21.1648.1648

Published: 2014

NARROW

HTLV-1 Dysregulates IL-6 and IL-10-JAK/STAT Signaling and Induces Leukemia/Lymphoma of Mature CD4+ T Cells with Regulatory T-Cell-like Signatures

The Presence and Possible Role of Virus-Host Chimeric Transcripts in Adult T-Cell Leukemia-Lymphoma

Dynamic Changes of Chromatin Structure and Transcriptome By Transient Expression of HTLV-1 Tax in ATL Cells

Genetic Evidence for Involvement of Human Endogenous Retrovirus Herv-Fc1 in the Pathogenesis of MPNs

The In Vivo infected Clones Have Mixed Immunophenotype and Malignant Transformation Is Characterized By Dominant Growth of CD4+CCR4+CD26-CD7- Cells in Human T Lymphotropic Virus Type 1 Infection

Histone Deacetylase Inhibitors Abolish HBZ Protein Expression and Induce Cell Death in HTLV-1 Related Adult T-Cell Leukemia-Lymphoma

Clonal Tracking of the Source of Red Cell and Platelet Production in Rhesus Macaques

Highly Sensitive Viral RNA-Seq Is a Powerful Tool to Analyze the Viral Transcripts in HTLV-1-Infected Individuals

A Descriptive Study of Viral RNA Sequences Identified from Single-Cell Analysis of Acute Myeloid Leukemia

Dual-Method Clone Tracking in Nonhuman Primates Confirms Long-Term Hematopoietic Reconstitution Initiated By Early Engrafting Clones

Monitoring of Adult T-Cell Leukemia-Lymphoma Cells in Patients Receiving Mogamulizumab, a Humanized Anti-CCR4 Monoclonal Antibody, Using T-Cell Receptor Repertoire Analysis

Hematopoietic Stem Cell Infected with HTLV-1 Functions As a Viral Reservoir In Vivo

Comprehensive Integration Site Analysis of Human Immunodeficiency Virus during In Vivo Infections Reveals Genomic Regions of Enrichment and Clonal Expansion

Intensive Chemotherapy with DA-Edoch Followed By Allogeneic Hematopoietic Stem Cell Transplantation Improved the Outcome in HTLV-1 Associated Adult T Cell Leukemia (ATL)

New Molecular Surrogate Assay for Genotoxicity Assessment of Gene Therapy Vectors (SAGA)

The Sea Urchin sns5 Chromatin Insulator Improves the Likelihood of Lentiviral Vectors in Erythroid Milieu By Organizing an Independent Chromatin Domain at the Integration Site

Activity of PIM Kinases in Chronic Lymphocytic Leukemia Modulates Tumor Cell Survival and Stromal Interactions through a Pleiotropic Mechanism Involving Modulation of CXCR4 - mTOR Pathway

The Combination of Belinostat with Zidovudine for Treatment of HTLV-I Related Adult T-Cell Leukemia-Lymphoma

Next-Generation Sequencing Reveal Proviral Genome and Transcriptome in Adult T-Cell Leukemia/Lymphoma

Cytotoxic T-Lymphocyte Analysis of Aggressive Types of Adult T-Cell Leukemia/Lymphoma Patients with Complete Remission after Intensive Combination Chemotherapy

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American Society of Hematology

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ASH Publications

American Society of Hematology

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