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Journal Articles

HTLV-1 persistence and the oncogenesis of adult T-cell leukemia/lymphoma

Charles R. M. Bangham

Blood (2023) 141 (19): 2299–2306.

https://doi.org/10.1182/blood.2022019332

Published: 2023

Journal Articles

Adult T-cell leukemia: genomic analysis

Charles R. M. Bangham

Blood (2022) 139 (7): 953–954.

https://doi.org/10.1182/blood.2021014450

Published: 2022

Journal Articles

Evolution of retrovirus-infected premalignant T-cell clones prior to adult T-cell leukemia/lymphoma diagnosis

Aileen G. Rowan, Richard Dillon, Aviva Witkover, Anat Melamed, Maria-Antonietta Demontis, Nicolas A. Gillet, Liew Jun Mun, Charles R. M. Bangham, Lucy B. Cook, Paul A. Fields, Graham P. Taylor

Blood (2020) 135 (23): 2023–2032.

https://doi.org/10.1182/blood.2019002665

Published: 2020

Includes: Supplemental data

Journal Articles

Hematopoietic Stem Cell Infected with HTLV-1 Functions As a Viral Reservoir In Vivo

Jun-ichirou Yasunaga, MDPhD, Rie Furuta, Michi Miura, Kenji Sugata, Akatsuki Saito, Akari Hirofumi, Takaharu Ueno, Norihiro Takenouchi, Jun-ichi Fujisawa, Masakazu Shimizu, Fumihiko Matsuda, MD PhD, Anat Melamed, Charles R. M. Bangham, Masao Matsuoka, MD PhD

Blood (2016) 128 (22): 1343.

https://doi.org/10.1182/blood.V128.22.1343.1343

Published: 2016

Journal Articles

HTLV-1 Proviral Load after Two Months' Treatment with Anti-CCR4 Monoclonal Antibody Mogamulizumab Predicts a Molecular Response to Disease and Durable Clinical Remission in Leukaemic Subtypes of Adult T-Cell Leukaemia/Lymphoma

Lucy B Cook, MB BS, PhD, Aileen G Rowan, PhD, Maria Antonietta Demontis, PhD, Sasha Marks, MB BS, PhD, Charles R. M. Bangham, Paul Fields, MD PhD, Graham P. Taylor, MD DSc

Blood (2016) 128 (22): 5356.

https://doi.org/10.1182/blood.V128.22.5356.5356

Published: 2016

Journal Articles

Whole Exome Sequencing of Flow Purified Tumour Cells Reveals Recurrently Mutated Genes and Pathways in Adult T-Cell Lymphoma/Leukaemia (ATLL)

Richard Dillon, MA, MRCP, FRCPath, Lucy Cook, Alka Saxena, Rosamond Nuamah, Ghazala Mirza, Amie Jaye, Michael Simpson, Sean Whittaker, Charles R. M. Bangham, Graham P. Taylor, Paul Fields, MDPhD

Blood (2015) 126 (23): 1469.

https://doi.org/10.1182/blood.V126.23.1469.1469

Published: 2015

Journal Articles

The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma

Lucy B. Cook, Anat Melamed, Heather Niederer, Mikel Valganon, Daniel Laydon, Letizia Foroni, Graham P. Taylor, Masao Matsuoka, Charles R. M. Bangham

Blood (2014) 123 (25): 3925–3931.

https://doi.org/10.1182/blood-2014-02-553602

Published: 2014

Includes: Supplemental data

Journal Articles

HTLV-1–infected T cells contain a single integrated provirus in natural infection

Lucy B. Cook, Aileen G. Rowan, Anat Melamed, Graham P. Taylor, Charles R. M. Bangham

Blood (2012) 120 (17): 3488–3490.

https://doi.org/10.1182/blood-2012-07-445593

Published: 2012

Journal Articles

Human T cells expressing affinity-matured TCR display accelerated responses but fail to recognize low density of MHC-peptide antigen

Sharyn Thomas, Shao-An Xue, Charles R. M. Bangham, Bent K. Jakobsen, Emma C. Morris, Hans J. Stauss

Blood (2011) 118 (2): 319–329.

https://doi.org/10.1182/blood-2010-12-326736

Published: 2011

Journal Articles

Kinetics and intracellular compartmentalization of HTLV-1 gene expression: nuclear retention of HBZ mRNAs

Francesca Rende, Ilaria Cavallari, Alberto Corradin, Micol Silic-Benussi, Frederic Toulza, Gianna M. Toffolo, Yuetsu Tanaka, Steven Jacobson, Graham P. Taylor, Donna M. D'Agostino, Charles R. M. Bangham, Vincenzo Ciminale

Blood (2011) 117 (18): 4855–4859.

https://doi.org/10.1182/blood-2010-11-316463

Published: 2011

Includes: Supplemental data

Journal Articles

The host genomic environment of the provirus determines the abundance of HTLV-1–infected T-cell clones

Nicolas A. Gillet, Nirav Malani, Anat Melamed, Niall Gormley, Richard Carter, David Bentley, Charles Berry, Frederic D. Bushman, Graham P. Taylor, Charles R. M. Bangham

Blood (2011) 117 (11): 3113–3122.

https://doi.org/10.1182/blood-2010-10-312926

Published: 2011

Includes: Supplemental data

Journal Articles

Highly active antiretroviral treatment against STLV-1 infection combining reverse transcriptase and HDAC inhibitors

Philippe V. Afonso, Mourad Mekaouche, Franck Mortreux, Frédéric Toulza, Antoine Moriceau, Eric Wattel, Antoine Gessain, Charles R. M. Bangham, Guy Dubreuil, Yves Plumelle, Olivier Hermine, Jérome Estaquier, Renaud Mahieux

Blood (2010) 116 (19): 3802–3808.

https://doi.org/10.1182/blood-2010-02-270751

Published: 2010

Includes: Supplemental data

Journal Articles

HTLV-1–Tax and ICAM-1 act on T-cell signal pathways to polarize the microtubule-organizing center at the virological synapse

Mohamed Nejmeddine, Veera S. Negi, Sohini Mukherjee, Yuetsu Tanaka, Kim Orth, Graham P. Taylor, Charles R. M. Bangham

Blood (2009) 114 (5): 1016–1025.

https://doi.org/10.1182/blood-2008-03-136770

Published: 2009

Includes: Supplemental data

Journal Articles

HTLV-1 infection: role of CTL efficiency

Charles R. M. Bangham

Blood (2008) 112 (6): 2176–2177.

https://doi.org/10.1182/blood-2008-06-163071

Published: 2008

Journal Articles

High frequency of CD4 + FoxP3 + cells in HTLV-1 infection: inverse correlation with HTLV-1–specific CTL response

Frederic Toulza, Adrian Heaps, Yuetsu Tanaka, Graham P. Taylor, Charles R. M. Bangham

Blood (2008) 111 (10): 5047–5053.

https://doi.org/10.1182/blood-2007-10-118539

Published: 2008

Includes: Supplemental data

Journal Articles

Strong induction of 4-1BB, a growth and survival promoting costimulatory receptor, in HTLV-1–infected cultured and patients' T cells by the viral Tax oncoprotein

Klemens Pichler, Tarek Kattan, Juliane Gentzsch, Andrea K. Kress, Graham P. Taylor, Charles R. M. Bangham, Ralph Grassmann

Blood (2008) 111 (9): 4741–4751.

https://doi.org/10.1182/blood-2007-10-115220

Published: 2008

Includes: Supplemental data

Journal Articles

Activation of interleukin-13 expression in T cells from HTLV-1-infected individuals and in chronically infected cell lines

Hye-Kyung Chung, Howard A. Young, Peter K. C. Goon, Gisela Heidecker, Gerald L. Princler, Osamu Shimozato, Graham P. Taylor, Charles R. M. Bangham, David Derse

Blood (2003) 102 (12): 4130–4136.

https://doi.org/10.1182/blood-2003-04-1043

Published: 2003

Journal Articles

Low frequency of CD94/NKG2A + T lymphocytes in patients with HTLV-1–associated myelopathy/tropical spastic paraparesis, but not in asymptomatic carriers

Mineki Saito, Veronique M. Braud, Peter Goon, Emmanuel Hanon, Graham P. Taylor, Akiko Saito, Nobutaka Eiraku, Yuetsu Tanaka, Koichiro Usuku, Jonathan N. Weber, Mitsuhiro Osame, Charles R. M. Bangham

Blood (2003) 102 (2): 577–584.

https://doi.org/10.1182/blood-2002-09-2855

Published: 2003

Journal Articles

High frequencies of Th1-type CD4 + T cells specific to HTLV-1 Env and Tax proteins in patients with HTLV-1–associated myelopathy/tropical spastic paraparesis

Peter K. C. Goon, Emmanuel Hanon, Tadahiko Igakura, Yuetsu Tanaka, Jonathan N. Weber, Graham P. Taylor, Charles R. M. Bangham

Blood (2002) 99 (9): 3335–3341.

https://doi.org/10.1182/blood.V99.9.3335

Published: 2002

Journal Articles

High production of interferon γ but not interleukin-2 by human T-lymphotropic virus type I–infected peripheral blood mononuclear cells

Emmanuel Hanon, Peter Goon, Graham P. Taylor, Hitoshi Hasegawa, Yuetsu Tanaka, Jonathan N. Weber, Charles R. M. Bangham

Blood (2001) 98 (3): 721–726.

https://doi.org/10.1182/blood.V98.3.721

Published: 2001

NARROW

HTLV-1 persistence and the oncogenesis of adult T-cell leukemia/lymphoma

Adult T-cell leukemia: genomic analysis

Evolution of retrovirus-infected premalignant T-cell clones prior to adult T-cell leukemia/lymphoma diagnosis

Hematopoietic Stem Cell Infected with HTLV-1 Functions As a Viral Reservoir In Vivo

HTLV-1 Proviral Load after Two Months' Treatment with Anti-CCR4 Monoclonal Antibody Mogamulizumab Predicts a Molecular Response to Disease and Durable Clinical Remission in Leukaemic Subtypes of Adult T-Cell Leukaemia/Lymphoma

Whole Exome Sequencing of Flow Purified Tumour Cells Reveals Recurrently Mutated Genes and Pathways in Adult T-Cell Lymphoma/Leukaemia (ATLL)

The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma

HTLV-1–infected T cells contain a single integrated provirus in natural infection

Human T cells expressing affinity-matured TCR display accelerated responses but fail to recognize low density of MHC-peptide antigen

Kinetics and intracellular compartmentalization of HTLV-1 gene expression: nuclear retention of HBZ mRNAs

The host genomic environment of the provirus determines the abundance of HTLV-1–infected T-cell clones

Highly active antiretroviral treatment against STLV-1 infection combining reverse transcriptase and HDAC inhibitors

HTLV-1–Tax and ICAM-1 act on T-cell signal pathways to polarize the microtubule-organizing center at the virological synapse

HTLV-1 infection: role of CTL efficiency

High frequency of CD4 + FoxP3 + cells in HTLV-1 infection: inverse correlation with HTLV-1–specific CTL response

Strong induction of 4-1BB, a growth and survival promoting costimulatory receptor, in HTLV-1–infected cultured and patients' T cells by the viral Tax oncoprotein

Activation of interleukin-13 expression in T cells from HTLV-1-infected individuals and in chronically infected cell lines

Low frequency of CD94/NKG2A + T lymphocytes in patients with HTLV-1–associated myelopathy/tropical spastic paraparesis, but not in asymptomatic carriers

High frequencies of Th1-type CD4 + T cells specific to HTLV-1 Env and Tax proteins in patients with HTLV-1–associated myelopathy/tropical spastic paraparesis

High production of interferon γ but not interleukin-2 by human T-lymphotropic virus type I–infected peripheral blood mononuclear cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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