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Howard A. Young
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Journal Articles

Perforin Is Dispensable for Anti-CD19 CAR-T Cell Cytotoxicity but Contributes to CAR-T Cell Contraction and Regulates Host Inflammatory Response

Kazusa Ishii, MDMPH, Christopher Daniel Chien, PhD, Rebecca Erwin-Cohen, PhD, Howard A Young, PhD, Terry J. Fry, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1918.
https://doi.org/10.1182/blood.V130.Suppl_1.1918.1918
Published: 2017
Journal Articles

IFN-γ causes aplastic anemia by altering hematopoietic stem/progenitor cell composition and disrupting lineage differentiation

Fan-ching Lin, Megan Karwan, Bahara Saleh, Deborah L. Hodge, Tim Chan, Kimberly C. Boelte, Jonathan R. Keller, Howard A. Young
Journal: Blood
Blood (2014) 124 (25): 3699–3708.
https://doi.org/10.1182/blood-2014-01-549527
Published: 2014
Includes: Supplemental data
Journal Articles

A novel role for IL-22R1 as a driver of inflammation

Ram Savan, Adelle P. McFarland, Della A. Reynolds, Lionel Feigenbaum, Karthika Ramakrishnan, Megan Karwan, Hidekazu Shirota, Dennis M. Klinman, Kieron Dunleavy, Stefania Pittaluga, Stephen K. Anderson, Raymond P. Donnelly, Wyndham H. Wilson, Howard A. Young
Journal: Blood
Blood (2011) 117 (2): 575–584.
https://doi.org/10.1182/blood-2010-05-285908
Published: 2011
Includes: Supplemental data
Journal Articles

Regulation of ITAM-positive receptors: role of IL-12 and IL-18

John R. Ortaldo, Robin Winkler-Pickett, Jon Wigginton, Meagan Horner, Earl W. Bere, Anna T. Mason, Narayan Bhat, James Cherry, Michael Sanford, Deborah L. Hodge, Howard A. Young
Journal: Blood
Blood (2006) 107 (4): 1468–1475.
https://doi.org/10.1182/blood-2005-04-1579
Published: 2006
Includes: Supplemental data
Journal Articles

Peroxisome proliferator-activated receptor-γ and its ligands attenuate biologic functions of human natural killer cells

Xia Zhang, Maria Cecilia Rodriguez-Galán, Jeff J. Subleski, John R. Ortaldo, Deborah L. Hodge, Ji-Ming Wang, Osamu Shimozato, Della A. Reynolds, Howard A. Young
Journal: Blood
Blood (2004) 104 (10): 3276–3284.
https://doi.org/10.1182/blood-2004-02-0664
Published: 2004
Journal Articles

Activation of interleukin-13 expression in T cells from HTLV-1-infected individuals and in chronically infected cell lines

Hye-Kyung Chung, Howard A. Young, Peter K. C. Goon, Gisela Heidecker, Gerald L. Princler, Osamu Shimozato, Graham P. Taylor, Charles R. M. Bangham, David Derse
Journal: Blood
Blood (2003) 102 (12): 4130–4136.
https://doi.org/10.1182/blood-2003-04-1043
Published: 2003
Journal Articles

Angiogenic effects of prostaglandin E 2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells

Rosalba Salcedo, Xia Zhang, Howard A. Young, Nelson Michael, Ken Wasserman, Wei-Hong Ma, Manuela Martins-Green, William J. Murphy, Joost J. Oppenheim
Journal: Blood
Blood (2003) 102 (6): 1966–1977.
https://doi.org/10.1182/blood-2002-11-3400
Published: 2003
Journal Articles

IL-4 synergistically enhances both IL-2– and IL-12–induced IFN-γ expression in murine NK cells

Jay H. Bream, Rafael E. Curiel, Cheng-Rong Yu, Charles E. Egwuagu, Michael J. Grusby, Thomas M. Aune, Howard A. Young
Journal: Blood
Blood (2003) 102 (1): 207–214.
https://doi.org/10.1182/blood-2002-08-2602
Published: 2003
Journal Articles

Interleukin 18 (IL-18) in synergy with IL-2 induces lethal lung injury in mice: a potential role for cytokines, chemokines, and natural killer cells in the pathogenesis of interstitial pneumonia

Masaki Okamoto, Seiya Kato, Kotaro Oizumi, Masaharu Kinoshita, Yoshimasa Inoue, Katsuaki Hoshino, Shizuo Akira, Andrew N. J. Mckenzie, Howard A. Young, Tomoaki Hoshino
Journal: Blood
Blood (2002) 99 (4): 1289–1298.
https://doi.org/10.1182/blood.V99.4.1289
Published: 2002
Journal Articles

Adenovirus type 5 vectors induce dendritic cell differentiation in human CD14 + monocytes cultured under serum-free conditions

Lyudmila A. Lyakh, Gary K. Koski, Howard A. Young, Sally E. Spence, Peter A. Cohen, Nancy R. Rice
Journal: Blood
Blood (2002) 99 (2): 600–608.
https://doi.org/10.1182/blood.V99.2.600
Published: 2002
Journal Articles

Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression

Rosalba Salcedo, Maria Lourdes Ponce, Howard A. Young, Ken Wasserman, Jerrold M. Ward, Hynda K. Kleinman, Joost J. Oppenheim, William J. Murphy
Journal: Blood
Blood (2000) 96 (1): 34–40.
https://doi.org/10.1182/blood.V96.1.34
Published: 2000
Journal Articles

Bone Marrow and Thymus Expression of Interferon-γ Results in Severe B-Cell Lineage Reduction, T-Cell Lineage Alterations, and Hematopoietic Progenitor Deficiencies

Howard A. Young, Dennis M. Klinman, Della A. Reynolds, Krzysztof J. Grzegorzewski, Aisuke Nii, Jerrold M. Ward, Robin T. Winkler-Pickett, John R. Ortaldo, James J. Kenny, Kristin L. Komschlies
Journal: Blood
Blood (1997) 89 (2): 583–595.
https://doi.org/10.1182/blood.V89.2.583
Published: 1997