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Journal Articles

Thrombin Generation Impairments in Platelet Function Disorders

Justin Brunet, BSc, Subia Tasneem, PhD, Georges E. Rivard, MD FRCPC, Catherine P.M. Hayward, MD

Blood (2018) 132 (Supplement 1): 1150.

https://doi.org/10.1182/blood-2018-99-110247

Published: 2018

Journal Articles

Bleeding Risks Associated with Confirmed Platelet Dense Granule Deficiency and/or Impaired Aggregation Responses

Janaki Iyer, PhD, Matthew Badin, Lucas Graf, Georges E. Rivard, MD, A. D. Paterson, Guillaume Pare, Catherine P.M. Hayward, MD PhD

Blood (2016) 128 (22): 3728.

https://doi.org/10.1182/blood.V128.22.3728.3728

Published: 2016

Journal Articles

Identification of Qualitative Platelet Disorders in Adolescent Women with Heavy Menstrual Bleeding

Kristina M. Haley, DO, Susan Lattimore, RN, Cara McDavitt, Ayesha Khader, Colin Boehnlein, Sandra Baker-Groberg, PhD, Anh Ngo, Owen J.T. McCarty, PhD, Michael Recht, MD PhD

Blood (2016) 128 (22): 4922.

https://doi.org/10.1182/blood.V128.22.4922.4922

Published: 2016

Journal Articles

Quebec Platelet Disorder Is Associated With Greater Than Expected Increases In Urokinase Plasminogen Activator In Granulocytes and Monocytes

Jessica Blavignac, PhD(c), H.BSc., Subia Tasneem, PhD, Andrew D Paterson, MD, John S Waye, Ph.D, Bhupinder Bharaj, PhD, Georges E Rivard, MD, Catherine P. M. Hayward, MD, PhD

Blood (2013) 122 (21): 3573.

https://doi.org/10.1182/blood.V122.21.3573.3573

Published: 2013

Journal Articles

Dysregulation of C10orf55 Expression in Megakaryocytic Cell Lineage From Quebec Platelet Disorder Individuals

Natalia Bunimov, PhD, Jessica Blavignac, BSc, Subia Tasneem, PhD, John S Waye, PhD, Andrew D Paterson, MD, Georges E Rivard, MD, Catherine PM Hayward, MD, PhD

Blood (2011) 118 (21): 2274.

https://doi.org/10.1182/blood.V118.21.2274.2274

Published: 2011

Journal Articles

Persons with Quebec platelet disorder have a tandem duplication of PLAU , the urokinase plasminogen activator gene

Andrew D. Paterson, Johanna M. Rommens, Bhupinder Bharaj, Jessica Blavignac, Isidro Wong, Maria Diamandis, John S. Waye, Georges E. Rivard, Catherine P. M. Hayward

Blood (2010) 115 (6): 1264–1266.

https://doi.org/10.1182/blood-2009-07-233965

Published: 2010

Includes: Supplemental data

Journal Articles

Increased expression of urokinase plasminogen activator in Quebec platelet disorder is linked to megakaryocyte differentiation

D. Kika Veljkovic, Georges E. Rivard, Maria Diamandis, Jessica Blavignac, Elisabeth M. Cramer-Bordé, Catherine P. M. Hayward

Blood (2009) 113 (7): 1535–1542.

https://doi.org/10.1182/blood-2008-08-172338

Published: 2009

Journal Articles

Quebec platelet disorder is linked to the urokinase plasminogen activator gene ( PLAU ) and increases expression of the linked allele in megakaryocytes

Maria Diamandis, Andrew D. Paterson, Johanna M. Rommens, D. Kika Veljkovic, Jessica Blavignac, Dennis E. Bulman, John S. Waye, Francine Derome, Georges E. Rivard, Catherine P. M. Hayward

Blood (2009) 113 (7): 1543–1546.

https://doi.org/10.1182/blood-2008-08-175216

Published: 2009

Includes: Supplemental data

Journal Articles

Quebec Platelet Disorder Is Caused by a Cis-Acting Mutation near the Plasminogen Activator Gene (PLAU) That Increases PLAU Transcription by Megakaryocytes.

Maria Diamandis, Andrew D Paterson, PhD, Johanna M Rommens, PhD, D. Kika Veljkovic, MD, Jessica Blavignac, John S Waye, PhD, Francine Derome, Georges E. Rivard, MD, Catherine PM Hayward, MD, PhD

Blood (2008) 112 (11): 3394.

https://doi.org/10.1182/blood.V112.11.3394.3394

Published: 2008

Journal Articles

Proteomics in the Study of Qualitative Platelet Defects: Validation of the Approach in the Gray Platelet Syndrome and Quebec Platelet Disorder.

Raj S. Kasthuri, MBBS, Lorraine B. Anderson, PhD, LeeAnn Higgins, PhD, Jorge Di Paola, MD, Georges E. Rivard, MD, FRCP(C), Catherine P.M. Hayward, MD, PhD, FRCP(C), Nigel S. Key, MB, FRCP

Blood (2007) 110 (11): 3900.

https://doi.org/10.1182/blood.V110.11.3900.3900

Published: 2007

Journal Articles

Urokinase-Type Plasminogen Activator Production by Cultured Megakaryocytes and Blood Outgrowth Endothelial Cells in the Quebec Platelet Disorder.

D. Kika Veljkovic, Ping Wang, Maria Diamandis, Georges E. Rivard, Catherine P.M. Hayward

Blood (2006) 108 (11): 1008.

https://doi.org/10.1182/blood.V108.11.1008.1008

Published: 2006

Journal Articles

Insights into Disturbed Hemostasis in the Quebec Platelet Disorder Using Thromboelastography, Blood Clots Formed at Low Shear, and Perfusion Studies of Fibrinolysis.

Maria Diamandis, Hon., BSc, Frederic Adam, PhD, Georges E. Rivard, MD, Walter H.A. Kahr, MD, PhD, Catherine P.M. Hayward, MD, PhD

Blood (2005) 106 (11): 2135.

https://doi.org/10.1182/blood.V106.11.2135.2135

Published: 2005

Journal Articles

Bleeding risks associated with inheritance of the Quebec platelet disorder

Heather McKay, Francine Derome, M. Anwar Haq, Susan Whittaker, Emmy Arnold, Frédéric Adam, Nancy M. Heddle, Georges E. Rivard, Catherine P. M. Hayward

Blood (2004) 104 (1): 159–165.

https://doi.org/10.1182/blood-2003-11-4077

Published: 2004

Journal Articles

Platelets from patients with the Quebec platelet disorder contain and secrete abnormal amounts of urokinase-type plasminogen activator

Walter H. A. Kahr, Shilun Zheng, Prameet M. Sheth, Menaka Pai, Alison Cowie, Madeleine Bouchard, Thomas J. Podor, Georges E. Rivard, Catherine P. M. Hayward

Blood (2001) 98 (2): 257–265.

https://doi.org/10.1182/blood.V98.2.257

Published: 2001

Journal Articles

Studies of a Second Family With the Quebec Platelet Disorder: Evidence That the Degradation of the α-Granule Membrane and Its Soluble Contents Are Not Secondary to a Defect in Targeting Proteins to α-Granules

Catherine P.M. Hayward, Elisabeth M. Cramer, William H. Kane, Shilun Zheng, Madeleine Bouchard, Jean-Marc Massé, Georges E. Rivard

Blood (1997) 89 (4): 1243–1253.

https://doi.org/10.1182/blood.V89.4.1243

Published: 1997

NARROW

Thrombin Generation Impairments in Platelet Function Disorders

Bleeding Risks Associated with Confirmed Platelet Dense Granule Deficiency and/or Impaired Aggregation Responses

Identification of Qualitative Platelet Disorders in Adolescent Women with Heavy Menstrual Bleeding

Quebec Platelet Disorder Is Associated With Greater Than Expected Increases In Urokinase Plasminogen Activator In Granulocytes and Monocytes

Dysregulation of C10orf55 Expression in Megakaryocytic Cell Lineage From Quebec Platelet Disorder Individuals

Persons with Quebec platelet disorder have a tandem duplication of PLAU , the urokinase plasminogen activator gene

Increased expression of urokinase plasminogen activator in Quebec platelet disorder is linked to megakaryocyte differentiation

Quebec platelet disorder is linked to the urokinase plasminogen activator gene ( PLAU ) and increases expression of the linked allele in megakaryocytes

Quebec Platelet Disorder Is Caused by a Cis-Acting Mutation near the Plasminogen Activator Gene (PLAU) That Increases PLAU Transcription by Megakaryocytes.

Proteomics in the Study of Qualitative Platelet Defects: Validation of the Approach in the Gray Platelet Syndrome and Quebec Platelet Disorder.

Urokinase-Type Plasminogen Activator Production by Cultured Megakaryocytes and Blood Outgrowth Endothelial Cells in the Quebec Platelet Disorder.

Insights into Disturbed Hemostasis in the Quebec Platelet Disorder Using Thromboelastography, Blood Clots Formed at Low Shear, and Perfusion Studies of Fibrinolysis.

Bleeding risks associated with inheritance of the Quebec platelet disorder

Platelets from patients with the Quebec platelet disorder contain and secrete abnormal amounts of urokinase-type plasminogen activator

Studies of a Second Family With the Quebec Platelet Disorder: Evidence That the Degradation of the α-Granule Membrane and Its Soluble Contents Are Not Secondary to a Defect in Targeting Proteins to α-Granules

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American Society of Hematology

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American Society of Hematology

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