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Nancy M. Heddle
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Journal Articles

ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia

Jason H. Karnes, Jerome Rollin, Jason B. Giles, Kiana L. Martinez, Heidi E. Steiner, Christian M. Shaffer, Yukihide Momozawa, Chihiro Inai, Andrei Bombin, Mingjian Shi, Jonathan D. Mosley, Ian Stanaway, Kathleen Selleng, Thomas Thiele, Taisei Mushiroda, Claire Pouplard, Nancy M. Heddle, Michiaki Kubo, Elizabeth J. Phillips, Theodore E. Warkentin, Yves Gruel, Andreas Greinacher, Dan M. Roden
Journal: Blood
Blood (2022) 140 (3): 274–284.
https://doi.org/10.1182/blood.2021014240
Published: 2022
Includes: Supplemental data
Journal Articles

Hemostatic efficacy of pathogen-inactivated vs untreated platelets: a randomized controlled trial

Clinical Trials & Observations
Pieter F. van der Meer, Paula F. Ypma, Nan van Geloven, Joost A. van Hilten, Rinie J. van Wordragen-Vlaswinkel, Okke Eissen, Jaap J. Zwaginga, Michael Trus, Erik A. M. Beckers, Peter te Boekhorst, Alan Tinmouth, Yulia Lin, Cyrus Hsia, David Lee, Philip J. Norris, Raymond P. Goodrich, Anneke Brand, Tor Hervig, Nancy M. Heddle, Johanna G. van der Bom, Jean-Louis H. Kerkhoffs
Journal: Blood
Blood (2018) 132 (2): 223–231.
https://doi.org/10.1182/blood-2018-02-831289
Published: 2018
Includes: Supplemental data
Journal Articles

The Effect of Platelet Transfusion on Death in the Intensive Care Unit

Donald M. Arnold, MD, Shuoyan Ning, MD, Rebecca Barty, MLT, CTRC, Yang Liu, MMath, Richard Cook, M. Math, PhD, Bram Rochberg, MD MSc, Alfonso Iorio, MD PhD, Andrew W. Shih, MD BSc, Nancy M Heddle, MSc
Journal: Blood
Blood (2016) 128 (22): 3850.
https://doi.org/10.1182/blood.V128.22.3850.3850
Published: 2016
Journal Articles

Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis

Clinical Trials & Observations
Paul E. Alexander, Rebecca Barty, Yutong Fei, Per Olav Vandvik, Menaka Pai, Reed A. C. Siemieniuk, Nancy M. Heddle, Neil Blumberg, Shelley L. McLeod, Jianping Liu, John W. Eikelboom, Gordon H. Guyatt
Journal: Blood
Blood (2016) 127 (4): 400–410.
https://doi.org/10.1182/blood-2015-09-670950
Published: 2016
Journal Articles

Non-Specific Hemostatic Agents (PCC, aPCC, rVIIa) for Reversal of Direct Oral Anticoagulant Effect in Patients with Major Bleeding Complications: A Retrospective Review

Deborah M. Siegal, MD MSc, Ron Movilla, Reda Siddiqui, Rebecca Barty, MLT, CTRC, Mark A. Crowther, MD MSc, FRCPC, Nancy M Heddle, MSc
Journal: Blood
Blood (2015) 126 (23): 1137.
https://doi.org/10.1182/blood.V126.23.1137.1137
Published: 2015
Journal Articles

Assessing Disease Stability of Patients with Myelodysplastic Syndrome for an Age of Blood Randomized Controlled Trial: A Chart Review

Naushin S. Sholapur, BHSc, MSc (C), Christopher M Hillis, MD FRCPC, Mark A. Crowther, MD MSc, FRCPC, Brian Leber, MD, Faiza Khokhar, BHSc, MD, Richard Cook, M. Math, PhD, Ronald Barr, MD, Nancy M. Heddle, MSc, FCSMLS(D)
Journal: Blood
Blood (2015) 126 (23): 5252.
https://doi.org/10.1182/blood.V126.23.5252.5252
Published: 2015
Journal Articles

A Qualitative Research Study to Understand Post-Transfusion Well-Being in Patients with Myelodysplastic Syndromes

Naushin S. Sholapur, BHSc, MSc (C), Shannon Lane, Christopher M Hillis, MD FRCPC, Mark A. Crowther, MD MSc, FRCPC, Brian Leber, MD, Richard Cook, M. Math, PhD, Ronald Barr, MD, Nancy M. Heddle, MSc, FCSMLS(D)
Journal: Blood
Blood (2015) 126 (23): 4446.
https://doi.org/10.1182/blood.V126.23.4446.4446
Published: 2015
Journal Articles

Management of Osteonecrosis By Adult and Pediatric Sickle Cell Providers

Dalal Hamza Mulla-Ali, BCh, BAO, LRCPSI, FRCPC, Kevin H.M. Kuo, MD MSc, FRCPC, Amanda M. Brandow, DO, MS, Nancy M. Heddle, MSc, FCSMLS(D), George A. Tomlinson, PhD, Aisha Bruce, MD BA, FRCPC
Journal: Blood
Blood (2015) 126 (23): 4465.
https://doi.org/10.1182/blood.V126.23.4465.4465
Published: 2015
Journal Articles

Red Cell Antigen Genotyping Compared to Standard Serological Phenotyping in Sickle Cell Disease Patients in Canada: Potential for Reducing Alloimmunization

Khalid S Al-Habsi, MD FRCPath, Andrew W. Shih, MD BSc, Rebecca Barty, MLT, CTRC, Grace Wang, Allahna Elahie, MLT, Mona Azzam, MD, Reda Siddiqui, Michael Parvizian, Nancy M Heddle, MSc, Uma H. Athale, MD, M.Sc., Mindy Rona Goldman, MD FRCP(C), Madeleine M Verhovsek, BSc, MD FRCPC
Journal: Blood
Blood (2015) 126 (23): 3404.
https://doi.org/10.1182/blood.V126.23.3404.3404
Published: 2015
Journal Articles

Combination of 4Ts score and PF4/H-PaGIA for diagnosis and management of heparin-induced thrombocytopenia: prospective cohort study

Clinical Trials & Observations
Lori-Ann Linkins, Shannon M. Bates, Agnes Y. Y. Lee, Nancy M. Heddle, Grace Wang, Theodore E. Warkentin
Journal: Blood
Blood (2015) 126 (5): 597–603.
https://doi.org/10.1182/blood-2014-12-618165
Published: 2015
Journal Articles

Platelet transfusions for critically ill patients with thrombocytopenia

CME
Lani Lieberman, Rachel S. Bercovitz, Naushin S. Sholapur, Nancy M. Heddle, Simon J. Stanworth, Donald M. Arnold
Journal: Blood
Blood (2014) 123 (8): 1146–1151.
https://doi.org/10.1182/blood-2013-02-435693
Published: 2014
Includes: Supplemental data
Journal Articles

The effect of rituximab on vaccine responses in patients with immune thrombocytopenia

Ishac Nazi, John G. Kelton, Mark Larché, Denis P. Snider, Nancy M. Heddle, Mark A. Crowther, Richard J. Cook, Alan T. Tinmouth, Joy Mangel, Donald M. Arnold
Journal: Blood
Blood (2013) 122 (11): 1946–1953.
https://doi.org/10.1182/blood-2013-04-494096
Published: 2013
Journal Articles

A pilot randomized trial of adjuvant rituximab or placebo for nonsplenectomized patients with immune thrombocytopenia

Clinical Trials & Observations
Donald M. Arnold, Nancy M. Heddle, Julie Carruthers, Deborah J. Cook, Mark A. Crowther, Ralph M. Meyer, Yang Liu, Richard J. Cook, Anne McLeod, Janet A. MacEachern, Joy Mangel, David Anderson, Linda Vickars, Alan Tinmouth, Andre C. Schuh, John G. Kelton
Journal: Blood
Blood (2012) 119 (6): 1356–1362.
https://doi.org/10.1182/blood-2011-08-374777
Published: 2012
Journal Articles

Combination immunosuppressant therapy for patients with chronic refractory immune thrombocytopenic purpura

Clinical Trials & Observations
Donald M. Arnold, Ishac Nazi, Aurelio Santos, Howard Chan, Nancy M. Heddle, Theodore E. Warkentin, John G. Kelton
Journal: Blood
Blood (2010) 115 (1): 29–31.
https://doi.org/10.1182/blood-2009-06-222448
Published: 2010
Journal Articles

Diagnostic Utility of Platelet Secretion Testing by ATP Release Assays: Results From a Prospective Study of Individuals Referred for Bleeding Disorder Assessments.

Menaka Pai, MD, FRCP(C), Grace Wang, MSc, Karen A Moffat, ART, FCSMLS(D), Jodi Seecharan, MLA, Yang Liu, MSc, Kathryn E Webert, MD, FRCP(C), Nancy M Heddle, MSc, FCSMLS(D), Catherine PM Hayward, MD, PhD, FRCP(C)
Journal: Blood
Blood (2009) 114 (22): 1314.
https://doi.org/10.1182/blood.V114.22.1314.1314
Published: 2009
Journal Articles

A randomized controlled trial comparing standard- and low-dose strategies for transfusion of platelets (SToP) to patients with thrombocytopenia

Nancy M. Heddle, Richard J. Cook, Alan Tinmouth, C. Tom Kouroukis, Tor Hervig, Ellen Klapper, Joseph M. Brandwein, Zbigniew M. Szczepiorkowski, James P. AuBuchon, Rebecca L. Barty, Ker-Ai Lee, for the SToP Study investigators of the BEST Collaborative
Journal: Blood
Blood (2009) 113 (7): 1564–1573.
https://doi.org/10.1182/blood-2008-09-178236
Published: 2009
Journal Articles

A Revisit of the Criteria To Define Remission in Patients with Idiopathic Thrombocytopenia Undergoing Splenectomy.

Howard H. Chan, FRCP(C), Rebecca Barty, MLT. CTRC, Richard J. Cook, PhD, John G. Kelton, FRCP(C), Nancy M. Heddle, FCSMLS(D)
Journal: Blood
Blood (2005) 106 (11): 3020.
https://doi.org/10.1182/blood.V106.11.3020.3020
Published: 2005
Journal Articles

A Multicenter, Randomized, Controlled Clinical Pilot Trial of the Feasibility of an Intensive RBC Transfusion Policy for Patients with Acute Leukemia Treated with Induction Chemotherapy or Stem Cell Transplant.

Kathryn E. Webert, MD, Richard J. Cook, PhD, Morris A. Blajchman, MD, Stephen Couban, MD, David M. Sutton, MD, Jeffrey H. Lipton, MD, Julie Carruthers, Joseph Brandwein, MD, Nancy M. Heddle, MSc, FCMLS(D)
Journal: Blood
Blood (2005) 106 (11): 4183.
https://doi.org/10.1182/blood.V106.11.4183.4183
Published: 2005
Journal Articles

Pitfalls in Interpreting Platelet Function Tests in Thrombocytopenic Patients Referred by a Hematologist for Diagnostic Testing: Results from a Single Center Prospective Study.

Heather M. McKay, Jodi L. Seecharan, Karen A. Moffat, Nancy M. Heddle, MSc, Catherine P.M. Hayward, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 3982.
https://doi.org/10.1182/blood.V106.11.3982.3982
Published: 2005
Journal Articles

The Use of Aprotinin to Reduce Transfusion Requirements in Children Undergoing Cardiac Surgery: A Meta-Analysis.

Donald M. Arnold, MD, FRCPC, Dean A. Fergusson, MHA, PhD, Anthony K. Chan, MBBS, FRCPC, Richard J. Cook, PhD, Graeme A. Fraser, MD, BSc, FRCPC, Wendy Lim, MD, FRCPS, Nancy M. Heddle, MSc, FCMLS(D), Morris A. Blajchman, MD, FRCPC, Deborah J. Cook, MD, MSc, FRCPC
Journal: Blood
Blood (2004) 104 (11): 2718.
https://doi.org/10.1182/blood.V104.11.2718.2718
Published: 2004