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Thomas Thiele
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Journal Articles

Anti-PF4 immunothrombosis without proximate heparin or adenovirus vector vaccine exposure

Clinical Trials & Observations
Linda Schönborn, Olga Esteban, Jan Wesche, Paulina Dobosz, Marta Broto, Sara Rovira Puig, Jessica Fuhrmann, Raquel Torres, Josep Serra, Roser Llevadot, Marta Palicio, Jing Jing Wang, Tom Paul Gordon, Edelgard Lindhoff-Last, Till Hoffmann, Lorenzo Alberio, Florian Langer, Christian Boehme, Eugenia Biguzzi, Leonie Grosse, Matthias Endres, Thomas Liman, Thomas Thiele, Theodore E. Warkentin, Andreas Greinacher
Journal: Blood
Blood (2023) 142 (26): 2305–2314.
https://doi.org/10.1182/blood.2023022136
Published: 2023
Includes: Supplemental data
Journal Articles

Thrombocytopenia and splenic platelet-directed immune responses after IV ChAdOx1 nCov-19 administration

Leo Nicolai, Alexander Leunig, Kami Pekayvaz, Max Esefeld, Afra Anjum, Justina Rath, Eva Riedlinger, Vincent Ehreiser, Magdalena Mader, Luke Eivers, Marie-Louise Hoffknecht, Zhe Zhang, Daniela Kugelmann, Dario Rossaro, Raphael Escaig, Rainer Kaiser, Vivien Polewka, Anna Titova, Tobias Petzold, Karsten Spiekermann, Matteo Iannacone, Thomas Thiele, Andreas Greinacher, Konstantin Stark, Steffen Massberg
Journal: Blood
Blood (2022) 140 (5): 478–490.
https://doi.org/10.1182/blood.2021014712
Published: 2022
Includes: Multimedia, Supplemental data
Journal Articles

ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia

Jason H. Karnes, Jerome Rollin, Jason B. Giles, Kiana L. Martinez, Heidi E. Steiner, Christian M. Shaffer, Yukihide Momozawa, Chihiro Inai, Andrei Bombin, Mingjian Shi, Jonathan D. Mosley, Ian Stanaway, Kathleen Selleng, Thomas Thiele, Taisei Mushiroda, Claire Pouplard, Nancy M. Heddle, Michiaki Kubo, Elizabeth J. Phillips, Theodore E. Warkentin, Yves Gruel, Andreas Greinacher, Dan M. Roden
Journal: Blood
Blood (2022) 140 (3): 274–284.
https://doi.org/10.1182/blood.2021014240
Published: 2022
Includes: Supplemental data
Journal Articles

Most anti-PF4 antibodies in vaccine-induced immune thrombotic thrombocytopenia are transient

Clinical Trials & Observations Brief Report
Linda Schönborn, Thomas Thiele, Lars Kaderali, Albrecht Günther, Till Hoffmann, Sabrina Edigna Seck, Kathleen Selleng, Andreas Greinacher
Journal: Blood
Blood (2022) 139 (12): 1903–1907.
https://doi.org/10.1182/blood.2021014214
Published: 2022
Includes: Supplemental data
Journal Articles

Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia

Andreas Greinacher, Kathleen Selleng, Raghavendra Palankar, Jan Wesche, Stefan Handtke, Martina Wolff, Konstanze Aurich, Michael Lalk, Karen Methling, Uwe Völker, Christian Hentschker, Stephan Michalik, Leif Steil, Alexander Reder, Linda Schönborn, Martin Beer, Kati Franzke, Andreas Büttner, Boris Fehse, Evi X. Stavrou, Chandini Rangaswamy, Reiner K. Mailer, Hanna Englert, Maike Frye, Thomas Thiele, Stefan Kochanek, Lea Krutzke, Florian Siegerist, Nicole Endlich, Theodore E. Warkentin, Thomas Renné
Journal: Blood
Blood (2021) 138 (22): 2256–2268.
https://doi.org/10.1182/blood.2021013231
Published: 2021
Includes: Supplemental data
Journal Articles

The Deglycosylated Form of 1E12, a Monoclonal Anti-PF4 IgG, Strongly Inhibits Antibody-Triggered Cellular Activation in Vaccine-Induced Thrombotic Thrombocytopenia, and Is a Potential New Treatment for Vιττ

Caroline Vayne, Raghavendra Palankar, Sandra Billy, Stefan Handtke, Thomas Thiele, Claire Pouplard, Andreas Greinacher, Yves Gruel, Jérôme Rollin
Journal: Blood
Blood (2021) 138 (Supplement 1): 582.
https://doi.org/10.1182/blood-2021-147922
Published: 2021
Journal Articles

Anti–platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein

Andreas Greinacher, Kathleen Selleng, Julia Mayerle, Raghavendra Palankar, Jan Wesche, Sven Reiche, Andrea Aebischer, Theodore E. Warkentin, Maximilian Muenchhoff, Johannes C. Hellmuth, Oliver T. Keppler, Daniel Duerschmied, Achim Lother, Siegbert Rieg, Meinrad Paul Gawaz, Karin Anne Lydia Mueller, Christian S. Scheer, Matthias Napp, Klaus Hahnenkamp, Guglielmo Lucchese, Antje Vogelgesang, Agnes Flöel, Piero Lovreglio, Angela Stufano, Rolf Marschalek, Thomas Thiele, for the Immune-Response in COVID-19 Vaccination Study Group
Journal: Blood
Blood (2021) 138 (14): 1269–1277.
https://doi.org/10.1182/blood.2021012938
Published: 2021
Includes: Supplemental data
Journal Articles

Frequency of positive anti-PF4/polyanion antibody tests after COVID-19 vaccination with ChAdOx1 nCoV-19 and BNT162b2

Clinical Trials & Observations Brief Report
Thomas Thiele, Lena Ulm, Silva Holtfreter, Linda Schönborn, Sven Olaf Kuhn, Christian Scheer, Theodore E. Warkentin, Barbara M. Bröker, Karsten Becker, Konstanze Aurich, Kathleen Selleng, Nils-Olaf Hübner, Andreas Greinacher
Journal: Blood
Blood (2021) 138 (4): 299–303.
https://doi.org/10.1182/blood.2021012217
Published: 2021
Journal Articles

A flow cytometric assay to detect platelet-activating antibodies in VITT after ChAdOx1 nCov-19 vaccination

Stefan Handtke, Martina Wolff, Carlo Zaninetti, Jan Wesche, Linda Schönborn, Konstanze Aurich, Lena Ulm, Nils-Olaf Hübner, Karsten Becker, Thomas Thiele, Andreas Greinacher
Journal: Blood
Blood (2021) 137 (26): 3656–3659.
https://doi.org/10.1182/blood.2021012064
Published: 2021
Includes: Supplemental data