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Journal Articles

Diamond-Blackfan anemia

Lydie Da Costa, Thierry Leblanc, Narla Mohandas

Blood (2020) 136 (11): 1262–1273.

https://doi.org/10.1182/blood.2019000947

Published: 2020

Journal Articles

Stat3 Is Activated By ROS to Uniquely Regulate Primitive Erythropoiesis

Zachary C. Murphy, PhD, Kathleen E. McGrath, PhD, James Palis, MD

Blood (2019) 134 (Supplement_1): 2216.

https://doi.org/10.1182/blood-2019-127229

Published: 2019

Journal Articles

Protein Cysteine Sulfenylation By CD36-Dependent Reactive Oxygen Species Signaling Promotes Platelet Activation

Moua Yang, PhD, Calvin Harberg, Wenjing Chen, Sarah L. Wynia-Smith, PhD, Kate S. Carroll, PhD, Jacek Zielonka, PhD, Roy L. Silverstein, MD, Brian C. Smith, PhD

Blood (2019) 134 (Supplement_1): 2338.

https://doi.org/10.1182/blood-2019-122465

Published: 2019

Journal Articles

Phenotypic Corrections of Ex Vivo Erythrocytes Derived from Chronic Hemolytic Anemia Patients Due to Krϋppel-like Factor 1 ( KLF-1 ) Mutations By AG-348: A Novel Synthetic Pyruvate Kinase Activator

Thidarat Suksangpleng, PhD, Kalaya Tachavanich, M.Sc., Suchada Riolueang, MSc, Supachai Ekwattanakit, PhDMD, Vip Viprakasit, MD DPhil

Blood (2019) 134 (Supplement_1): 2220.

https://doi.org/10.1182/blood-2019-131720

Published: 2019

Journal Articles

Elucidating the Role of IL6 in Stress Erythropoiesis and in the Development of Anemia Under Inflammatory Conditions

Sayantani Sinha, PhD, Ritama Gupta, PhD, Jianbing Zhang, PhD, Amaliris Guerra, PhD, Ping La, Sara Gardenghi, PhD, Stefano Rivella, PhD

Blood (2019) 134 (Supplement_1): 940.

https://doi.org/10.1182/blood-2019-128826

Published: 2019

Journal Articles

Relationship of Host Genetic Factors with Severe Malaria in Nigerian Children

Olukemi Amodu, PhD, Binal N. Shah, Subulade Ademola, PhD, Bamidele Tayo, PhD, Victor R Gordeuk, MD

Blood (2019) 134 (Supplement_1): 942.

https://doi.org/10.1182/blood-2019-132190

Published: 2019

Journal Articles

Genetically Engineered Hematopoietic Progenitors Derived from Human Induced Pluripotent Stem Cells Achieve the Feeder-Free and Robust Production of Neutrophils with the Functional Capacity In Vivo

Masashi Miyauchi, Yusuke ITO, MD, Fumio Nakahara, MD PhD, Fumi Nakamura, MD PhD, Yuki Iwasaki, Taiki Kawagoshi, Yuki Kagoya, MD PhD, Shunya Arai, MD PhD, Mineo Kurokawa, MD PhD

Blood (2019) 134 (Supplement_1): 720.

https://doi.org/10.1182/blood-2019-126348

Published: 2019

Journal Articles

Intravenous Iron Promotes Low-Grade Inflammation in Anemic Patients By Triggering Macrophage Activation

Francesca Vinchi, PhD, Annalisa Castagna, B.S., PhD, Milene Costa da Silva, Fabiana Busti, MD PhD, Giacomo Marchi, MD, Richard Sparla, Martina U. Muckenthaler, PhD, Domenico Girelli, MD, PhD

Blood (2019) 134 (Supplement_1): 957.

https://doi.org/10.1182/blood-2019-132235

Published: 2019

Journal Articles

Glutaminase Inhibition Overcomes Acquired Resistance to Mitochondrial Complex I in NOTCH1-Driven T-Cell Acute Lymphoblastic Leukemias (T-ALL) Via Block of Glutamine Driven Reductive Metabolism

Blood (2019) 134 (Supplement_1): 806.

https://doi.org/10.1182/blood-2019-128930

Published: 2019

Journal Articles

Complete Remission after the First Cycle of Induction Chemotherapy Determines the Clinical Efficacy of Relapse-Preventive Immunotherapy in Acute Myeloid Leukemia

Malin S Nilsson, MSc, Alexander Hallner, PhD, Mats Brune, MD PhD, Staffan Nilsson, PhD, Fredrik B Thorén, PhD, Anna Martner, PhD, Kristoffer Hellstrand, MD PhD

Blood (2019) 134 (Supplement_1): 1318.

https://doi.org/10.1182/blood-2019-130345

Published: 2019

Journal Articles

Ibrutinib in Combination with Venetoclax Decreases Mitochondrial Bioenergetics through the Impaired BTK, AKT and AMPK/SIRT/PGC-1α Signaling Pathway in CLL

Subir Roy Chowdhury, MD PhD, Amandeep Singh, MSc, Edwin Nguyen, Aaron Marshall, PhD, James B. Johnston, MD, Spencer Bruce Gibson, PhD, Versha Banerji, MD

Blood (2019) 134 (Supplement_1): 1282.

https://doi.org/10.1182/blood-2019-127562

Published: 2019

Journal Articles

Targeting DNA Damage and Repair in Acute Myeloid Leukemia Carrying Internal Tandem Duplication of Fms-like Tyrosine Kinase 3 (FLT3-ITD) - a Mechanistic Study

Ka Lam Nelson Ng, PhD, Claire Lynn, Thomas Wing Yan Leung, Eric Chi Wai So, PhD, Anskar Yu Hung Leung, MD PhD

Blood (2019) 134 (Supplement_1): 1261.

https://doi.org/10.1182/blood-2019-129472

Published: 2019

Journal Articles

Lineage Tracing in Chronic Lymphocytic Leukemia Reveals Clones with Stable Gene Expression States That Differentially Respond to Therapy

Catherine Gutierrez, Aziz Al'Khafaji, B.S., Eric Brenner, B.S., Russell Durrett, B.S., M.S., Kaitlyn Johnson, B.S., M.S., Wandi Zhang, MD, Shuqiang Li, PhD, Kenneth J. Livak, PhD, Donna S Neuberg, ScD, Amy Brock, PhD, Catherine J. Wu, MD

Blood (2019) 134 (Supplement_1): 1229.

https://doi.org/10.1182/blood-2019-129303

Published: 2019

Journal Articles

Eltrombopag Improves Erythroid Differentiation in a Human iPSC Model of Diamond Blackfan Anemia

Husam Qanash, MSc, Kaari Linask, Jeanette Beers, Keyvan Keyvanfar, Sara Young-Baird, Waleed Hakami, Richard H. Smith, Jizhong Zou, Andre Larochelle, MD PhD

Blood (2019) 134 (Supplement_1): 1214.

https://doi.org/10.1182/blood-2019-121822

Published: 2019

Journal Articles

Mutant ASXL1 Disrupts Paraspeckle Formation through Aberrant Interaction with Nono in Hematopoietic Cells

Yamamoto Keita, MD, Susumu Goyama, MD PhD, Shuhei Asada, MD PhD, Takeshi Fujino, MD, Tomofusa Fukuyama, MD PhD, Yosuke Tanaka, MD, Ayana Kon, MD PhD, Yasuhito Nannya, MD PhD, Seishi Ogawa, MD PhD, Reina Onoguchi, PhD, Nobuyoshi Akimitsu, PhD, Toshio Kitamura, MD PhD

Blood (2019) 134 (Supplement_1): 2514.

https://doi.org/10.1182/blood-2019-125472

Published: 2019

Journal Articles

PKC-Epsilon Overexpression Is Associated with Poor Outcomes in AML and Promotes Chemoresistance and Hematopoietic Stem Cell Quiescence

Rachael Louise Nicholson, BSc, Steven Knapper, DM, Alex Tonks, PhD, Richard L Darley, PhD

Blood (2019) 134 (Supplement_1): 2704.

https://doi.org/10.1182/blood-2019-128184

Published: 2019

Journal Articles

The Influence of the Age of the Bone Marrow Microenvironment on Leukaemia Progression

Costanza Zanetti, MSc, Joscha Ender, Mark Hartmann, Joschka Hey, MSc, BSc, Parimala Sonika Godavarthy, MSc, Eva Weissenberger, Rahul Kumar, PhD, Markus Metzler, MD PhD, Zhaohui Gu, PhD, Kathryn G. Roberts, PhD, Natalie Filmann, Clara D. Bloomfield, MD, Wendy Stock, MD, Charles G. Mullighan, MBBS, MD, Daniel B. Lipka, Daniela S. Krause, MD

Blood (2019) 134 (Supplement_1): 2748.

https://doi.org/10.1182/blood-2019-122797

Published: 2019

Journal Articles

Proteomic Analysis Identifies Mechanism(s) of Overcoming Bortezomib-Resistance Via Targeting Ubiquitin Receptor Rpn13

Ting Du, PhD, Yan Song, PhD, Arghya Ray, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD

Blood (2019) 134 (Supplement_1): 3074.

https://doi.org/10.1182/blood-2019-130236

Published: 2019

Journal Articles

Efficacy of OR21, a Novel Oral Demethylating Agent in Chronic Myeloid Leukemia

Kazuharu Kamachi, MD, Hiroshi Ureshino, MD, Nao Yoshida, MD, Yuki Kurahashi, Tatsuro Watanabe, PhD, Seiji Okada, MD PhD, Shinya Kimura, MD PhD

Blood (2019) 134 (Supplement_1): 5365.

https://doi.org/10.1182/blood-2019-125460

Published: 2019

Journal Articles

Arsenic Trioxide Upregulates Cereblon mRNA Expression and Potentiates Sensitivity of SKM-1 and MDS-L Cells to Lenalidomide

Radka Bokorová, Ota Fuchs, PhD, Denisa Myslivcova, PhD, Jaroslav Cermak

Blood (2019) 134 (Supplement_1): 5397.

https://doi.org/10.1182/blood-2019-126443

Published: 2019

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Diamond-Blackfan anemia

Stat3 Is Activated By ROS to Uniquely Regulate Primitive Erythropoiesis

Protein Cysteine Sulfenylation By CD36-Dependent Reactive Oxygen Species Signaling Promotes Platelet Activation

Phenotypic Corrections of Ex Vivo Erythrocytes Derived from Chronic Hemolytic Anemia Patients Due to Krϋppel-like Factor 1 ( KLF-1 ) Mutations By AG-348: A Novel Synthetic Pyruvate Kinase Activator

Elucidating the Role of IL6 in Stress Erythropoiesis and in the Development of Anemia Under Inflammatory Conditions

Relationship of Host Genetic Factors with Severe Malaria in Nigerian Children

Genetically Engineered Hematopoietic Progenitors Derived from Human Induced Pluripotent Stem Cells Achieve the Feeder-Free and Robust Production of Neutrophils with the Functional Capacity In Vivo

Intravenous Iron Promotes Low-Grade Inflammation in Anemic Patients By Triggering Macrophage Activation

Glutaminase Inhibition Overcomes Acquired Resistance to Mitochondrial Complex I in NOTCH1-Driven T-Cell Acute Lymphoblastic Leukemias (T-ALL) Via Block of Glutamine Driven Reductive Metabolism

Complete Remission after the First Cycle of Induction Chemotherapy Determines the Clinical Efficacy of Relapse-Preventive Immunotherapy in Acute Myeloid Leukemia

Ibrutinib in Combination with Venetoclax Decreases Mitochondrial Bioenergetics through the Impaired BTK, AKT and AMPK/SIRT/PGC-1α Signaling Pathway in CLL

Targeting DNA Damage and Repair in Acute Myeloid Leukemia Carrying Internal Tandem Duplication of Fms-like Tyrosine Kinase 3 (FLT3-ITD) - a Mechanistic Study

Lineage Tracing in Chronic Lymphocytic Leukemia Reveals Clones with Stable Gene Expression States That Differentially Respond to Therapy

Eltrombopag Improves Erythroid Differentiation in a Human iPSC Model of Diamond Blackfan Anemia

Mutant ASXL1 Disrupts Paraspeckle Formation through Aberrant Interaction with Nono in Hematopoietic Cells

PKC-Epsilon Overexpression Is Associated with Poor Outcomes in AML and Promotes Chemoresistance and Hematopoietic Stem Cell Quiescence

The Influence of the Age of the Bone Marrow Microenvironment on Leukaemia Progression

Proteomic Analysis Identifies Mechanism(s) of Overcoming Bortezomib-Resistance Via Targeting Ubiquitin Receptor Rpn13

Efficacy of OR21, a Novel Oral Demethylating Agent in Chronic Myeloid Leukemia

Arsenic Trioxide Upregulates Cereblon mRNA Expression and Potentiates Sensitivity of SKM-1 and MDS-L Cells to Lenalidomide

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