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Journal Articles

Homeostatic Regulation of Apoptosis Governs Thymus Regeneration

Sinéad Kinsella, MSc,PhD, Kirsten Cooper, Lorenzo Iovino, MD, Paul DeRoos, Reema Jain, PhD, Jarrod A Dudakov, PhD

Blood (2019) 134 (Supplement_1): 587.

https://doi.org/10.1182/blood-2019-131513

Published: 2019

Journal Articles

ATRA Could Correct the Defective S1P-Mediated Cytoskeletal Reorganization in Proplatelet Formation of ITP

Qiu-Sha Huang, Jing Xue, Chen-Cong Wang, Ya-Zhen Qin, Lan-Ping Xu, Kaiyan Liu, Xiao-Jun Huang, MD, Xiao-Hui Zhang

Blood (2019) 134 (Supplement_1): 218.

https://doi.org/10.1182/blood-2019-126384

Published: 2019

Journal Articles

RAC1 Inhibitor EHT1864 and Venetoclax Overcome Midostaurin Resistance in Acute Myeloid Leukemia

Blood (2019) 134 (Supplement_1): 1277.

https://doi.org/10.1182/blood-2019-129762

Published: 2019

Journal Articles

NOD2 Acts As a Master Regulator of Endogenous Thymic Regeneration

Sinéad Kinsella, MSc,PhD, Kirsten Cooper, Paul DeRoos, Reema Jain, PhD, Lorenzo Iovino, MD, Jarrod A Dudakov, PhD

Blood (2018) 132 (Supplement 1): 478.

https://doi.org/10.1182/blood-2018-99-115386

Published: 2018

Journal Articles

Wnt5a Induces Interleukin-6 Via a ROR1-Dependent Pathway in Chronic Lymphocytic Leukemia, Leading to Leukemia-Cell Activation of STAT3

Yun Chen, PhD, Liguang Chen, PhD, Jian Yu, PhD, Ling Zhang, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD

Blood (2017) 130 (Supplement 1): 4282.

https://doi.org/10.1182/blood.V130.Suppl_1.4282.4282

Published: 2017

Journal Articles

Durable and Specific Inhibition of ROR1 Signaling Associates with Prolonged Progression Free Survival in Patients with Chronic Lymphocytic Leukemia Treated with Cirmtuzumab

Michael Choi, MD, George F. Widhopf II, PhD, Jian Yu, PhD, Liguang Chen, PhD, Md. Kamrul Hasan, PhD, Laura Z. Rassenti, PhD, Emily Pittman, PhD, Karen Messer, PhD, Charlene Gutierrez, BS, Reilly Lilianna Kidwell, BSc, Charles E. Prussak, PharmD, PhD, Januario E Castro, MD, Catriona Jamieson, MD PhD, Thomas J. Kipps, MD

Blood (2017) 130 (Supplement 1): 829.

https://doi.org/10.1182/blood.V130.Suppl_1.829.829

Published: 2017

Journal Articles

Nurse-like Cells Express High-Levels of Wnt5a, Which Induces ROR1-Dependent Signaling That Promotes Migration and Survival of Neoplastic Cells in Chronic Lymphocytic Leukemia

Yun Chen, PhD, Liguang Chen, PhD, Jian Yu, PhD, Ling Zhang, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD

Blood (2017) 130 (Supplement 1): 3007.

https://doi.org/10.1182/blood.V130.Suppl_1.3007.3007

Published: 2017

Journal Articles

Diaphanous-Related Formin Protein mDia2 Regulates Hematopoietic Stem and Progenitor Cell Functions through Srf-Integrins Pathway

Yang Mei, PhD, Baobing Zhao, PhD, Jingxin Zhang, PhD, Xu Han, PhD, Jing Yang, Peng Ji, MDPhD

Blood (2017) 130 (Supplement 1): 2421.

https://doi.org/10.1182/blood.V130.Suppl_1.2421.2421

Published: 2017

Journal Articles

Immunotherapeutic Targeting of ROR1-Dependent, Non-Canonical Wnt5a-Signaling By Cirmtuzumab: A First-in-Human Phase I Trial for Patients with Intractable Chronic Lymphocytic Leukemia

Michael Y. Choi, MD, George F. Widhopf, II, PhD, Jian Yu, PhD, Reilly L Kidwell, BS, BA, CCRC, Laura Z. Rassenti, PhD, Charlene Gutierrez, Susette Gorak, Tiffany Juarez, PhD, Emily Pittman, PhD, Hongying Li, PhD, Karen Messer, PhD, Charles Prussak, PhD, Januario E. Castro, MD, Catriona Jamieson, MD PhD, Thomas J. Kipps, MD, PhD

Blood (2016) 128 (22): 3224.

https://doi.org/10.1182/blood.V128.22.3224.3224

Published: 2016

Journal Articles

Wnt5a Induces Association of ROR1 with 14-3-3ζ to Enhance Chemotaxis and Proliferation in Chronic Lymphocytic Leukemia

Jian Yu, PhD, Liguang Chen, PhD, Yun Chen, PhD, Ling Zhang, Laura Z. Rassenti, PhD, George F. Widhopf, II, PhD, Zhouxin Shen, PhD, Steven P. Briggs, PhD, Thomas J. Kipps, MD, PhD

Blood (2016) 128 (22): 349.

https://doi.org/10.1182/blood.V128.22.349.349

Published: 2016

Journal Articles

Identification of Phenotypic Modulation of Angiotensin-(1-7) in Thrombin-Stimulated Human Aortic Endothelial Cells from iTRAQ Quantitative Proteomics

Ching-Tien Peng, MD MPH, Kang-Hsi Wu, MD

Blood (2016) 128 (22): 4999.

https://doi.org/10.1182/blood.V128.22.4999.4999

Published: 2016

Journal Articles

Comprehensive Analysis of the Structural, Biochemical and Signaling Differences of the p210 and p185 Isoforms of Bcr-Abl in CML and B-ALL

Oliver Hantschel, PhD, Sina Reckel, Hamelin Romain, Florence Armand, Delphine Harduin, Shohei Koide, Volker Dötsch, Marc Moniatte

Blood (2016) 128 (22): 4238.

https://doi.org/10.1182/blood.V128.22.4238.4238

Published: 2016

Journal Articles

B Cells of the Proliferative Fraction of CLL Clones Exhibit Activated B-Cell and Myeloid-Cell Signatures Suggesting Enhanced Antigen-Presentation, Integrin Responsiveness, and IL-4 Receptiveness: Additional Targets for CLL Therapy

Xiao-Jie Yan, MD PhD, Florencia Palacios, PhD, Wentian Li, PhD, Sophia Yancopoulos, PhD, Carlo Calissano, MD, Jacqueline C. Barrientos, MD, Steven L. Allen, MD, Jonathan E. Kolitz, MD, Kanti Rai, MD, Nicholas Chiorazzi, MD

Blood (2016) 128 (22): 302.

https://doi.org/10.1182/blood.V128.22.302.302

Published: 2016

Journal Articles

Towards a Targeted Therapy:Phosphoproteomics Reveals Signaling Pathways That Are Normalized in AML Cells Following Treatment with Anti-CD44 Antibodies

Heba M. Jalal El-Din, Jasmeen S. Merzaban, PhD

Blood (2015) 126 (23): 1402.

https://doi.org/10.1182/blood.V126.23.1402.1402

Published: 2015

Journal Articles

ARHGAP21 Is Upregulated and Triggers the Modulation of Rho Gtpase Signaling Pathways during Megakaryocytic Differentiation

Vanessa Aline Bernusso, Mariana Lazarini, PhD, João Agostinho Machado-Neto, PhD, Karin Spat Albino Barcellos, PhD, Sara Teresinha Olalla Saad, PhD MD

Blood (2015) 126 (23): 4760.

https://doi.org/10.1182/blood.V126.23.4760.4760

Published: 2015

Journal Articles

Histone Deacetylase 6 (HDAC6) Regulates Gene Transcription and Enucleation during Erythroid Differentiation

Xuehui Li, PhD, Yurong Yang, PhD, Jianrong Lu, PhD, Timothy McKinsey, PhD, Peng Ji, MD PhD, Yi Qiu, PhD

Blood (2014) 124 (21): 447.

https://doi.org/10.1182/blood.V124.21.447.447

Published: 2014

Journal Articles

Rac1 Gtpase Promotes Hematopoietic Stem Cell Migration, Self-Renewal and Participates in Leukemia Initiation and Maintenance

Shuying Chen, MD, Qing Rao, MS, Haiyan Xing, MS, Jing Yu, MD, Huan Li, Min Wang, Jianxiang Wang, MD

Blood (2014) 124 (21): 2923.

https://doi.org/10.1182/blood.V124.21.2923.2923

Published: 2014

Journal Articles

Investigation of T Cell Subsets and Germinal Center Reaction in a B Cell Malignancy Model of Mice Deficient in the Lymphoma Hyermutable Gene Rhoh

Anja Troeger, MD, Jenna Wood, David A. Williams, MD

Blood (2014) 124 (21): 3294.

https://doi.org/10.1182/blood.V124.21.3294.3294

Published: 2014

Journal Articles

Kinase Activity Of Pak2, An Effector Of Rac/CDC42 and Its Interaction With β-PIX Is Required For Murine Hematopoietic Stem Cell Shape, F-Actin Formation, Directional Migration In Vitro and For HSPC Homing To Bone Marrow In Vivo

Pavankumar N.G. Reddy, PhD, Jenna Wood, Chad E Harris, Ke Xu, Meaghan McGuinness, Maria Radu, MD PhD, Rachelle Kosoff, Jonathan Chernoff, MD, PhD, David A. Williams, MD

Blood (2013) 122 (21): 2419.

https://doi.org/10.1182/blood.V122.21.2419.2419

Published: 2013

Journal Articles

Trisomy 12 CLL Cells Have High Surface Expression Of Integrins Involved In Lymphocyte Trafficking But This Does Not Translate Into Improved LFA-1-Mediated Motility

Conor J. O'Donovan, Alan G. Ramsay, PhD, Fabienne McClanahan, MD, Laura Rassenti, PhD, Thomas J. Kipps, MD, PhD, John Gribben, MD, DSc, John C. Riches, MD

Blood (2013) 122 (21): 4159.

https://doi.org/10.1182/blood.V122.21.4159.4159

Published: 2013

NARROW

Homeostatic Regulation of Apoptosis Governs Thymus Regeneration

ATRA Could Correct the Defective S1P-Mediated Cytoskeletal Reorganization in Proplatelet Formation of ITP

RAC1 Inhibitor EHT1864 and Venetoclax Overcome Midostaurin Resistance in Acute Myeloid Leukemia

NOD2 Acts As a Master Regulator of Endogenous Thymic Regeneration

Wnt5a Induces Interleukin-6 Via a ROR1-Dependent Pathway in Chronic Lymphocytic Leukemia, Leading to Leukemia-Cell Activation of STAT3

Durable and Specific Inhibition of ROR1 Signaling Associates with Prolonged Progression Free Survival in Patients with Chronic Lymphocytic Leukemia Treated with Cirmtuzumab

Nurse-like Cells Express High-Levels of Wnt5a, Which Induces ROR1-Dependent Signaling That Promotes Migration and Survival of Neoplastic Cells in Chronic Lymphocytic Leukemia

Diaphanous-Related Formin Protein mDia2 Regulates Hematopoietic Stem and Progenitor Cell Functions through Srf-Integrins Pathway

Immunotherapeutic Targeting of ROR1-Dependent, Non-Canonical Wnt5a-Signaling By Cirmtuzumab: A First-in-Human Phase I Trial for Patients with Intractable Chronic Lymphocytic Leukemia

Wnt5a Induces Association of ROR1 with 14-3-3ζ to Enhance Chemotaxis and Proliferation in Chronic Lymphocytic Leukemia

Identification of Phenotypic Modulation of Angiotensin-(1-7) in Thrombin-Stimulated Human Aortic Endothelial Cells from iTRAQ Quantitative Proteomics

Comprehensive Analysis of the Structural, Biochemical and Signaling Differences of the p210 and p185 Isoforms of Bcr-Abl in CML and B-ALL

B Cells of the Proliferative Fraction of CLL Clones Exhibit Activated B-Cell and Myeloid-Cell Signatures Suggesting Enhanced Antigen-Presentation, Integrin Responsiveness, and IL-4 Receptiveness: Additional Targets for CLL Therapy

Towards a Targeted Therapy:Phosphoproteomics Reveals Signaling Pathways That Are Normalized in AML Cells Following Treatment with Anti-CD44 Antibodies

ARHGAP21 Is Upregulated and Triggers the Modulation of Rho Gtpase Signaling Pathways during Megakaryocytic Differentiation

Histone Deacetylase 6 (HDAC6) Regulates Gene Transcription and Enucleation during Erythroid Differentiation

Rac1 Gtpase Promotes Hematopoietic Stem Cell Migration, Self-Renewal and Participates in Leukemia Initiation and Maintenance

Investigation of T Cell Subsets and Germinal Center Reaction in a B Cell Malignancy Model of Mice Deficient in the Lymphoma Hyermutable Gene Rhoh

Kinase Activity Of Pak2, An Effector Of Rac/CDC42 and Its Interaction With β-PIX Is Required For Murine Hematopoietic Stem Cell Shape, F-Actin Formation, Directional Migration In Vitro and For HSPC Homing To Bone Marrow In Vivo

Trisomy 12 CLL Cells Have High Surface Expression Of Integrins Involved In Lymphocyte Trafficking But This Does Not Translate Into Improved LFA-1-Mediated Motility

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American Society of Hematology

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ASH Publications

American Society of Hematology

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