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Journal Articles

Critical role of tripartite fusion and LBD truncation in certain RARA - and all RARG -related atypical APL

Xiaosu Zhou, Xue Chen, Jiaqi Chen, Lijun Wen, Zhanglin Zhang, Ya-Zhen Qin, Panxiang Cao, Haizhou Xing, Yingchang Mi, Wei Wang, Guangsen Zhang, Ji Li, Huanling Wu, Zhifen Zhang, Jian Zhang, Zhan Su, Fang Wang, Yang Zhang, Xiaoli Ma, Jiancheng Fang, Ping Wu, Tong Wang, Gaowei Fan, Yang Zhao, David Jin, Xian Zhang, Xiujuan Ma, Qisheng Wu, Zhihua Zhang, Linya Wang, Futian Ma, Xia Xiao, Chengye Wu, Kai Sun, Ruijie Tang, Yun Zhang, Sanyun Wu, Ran Gao, Leping Zhang, Huyong Zheng, Yanli Zhao, Hong-Hu Zhu, Daopei Lu, Peihua Lu, Suning Chen, Hongxing Liu
Journal: Blood
Blood (2024) 144 (14): 1471–1485.
https://doi.org/10.1182/blood.2024023883
Published: 2024
Includes: Supplemental data
Journal Articles

A Completely Oral Regimen Including Oral Etoposide As Cytoreductive Chemotherapy Combined with All Trans Retinoic Acid and Oral Arsenic for Induction Therapy in Patients with High-Risk APL：Comparable to Intravenous Cytoreductive Therapy

Feifei Tang, Wen-Bing Duan, Xiao-Hong Liu, Sheng-Ye Lu, Xiao-Su Zhao, Ya-Zhen Qin, Jin-Song Jia, Jing Wang, Li-Zhong Gong, Qian Jiang, Zhao Ting, Hong-Xia Shi, Ying-Jun Chang, Xiao-Jun Huang, Hao Jiang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4288.
https://doi.org/10.1182/blood-2023-188657
Published: 2023
Journal Articles

Comparison of Safety and Efficacy between Venetoclax Combined with CAG (cytarabine, aclarubicin, G-CSF) Regimen and CAG Regimen Alone in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Wen-Jing Yu, Ying Wu, Qi Chen, Xiaolu Zhu, Xu-Ying Pei, Jin-Song Jia, Jing Wang, Xiao-Su Zhao, Ying-Jun Chang, Yue-Yun Lai, Hong-Xia Shi, Guo-Rui Ruan, Ya-Zhen Qin, Xiao-Hong Liu, Xiao Jun Huang, Hao Jiang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1525.
https://doi.org/10.1182/blood-2023-184665
Published: 2023
Journal Articles

Trinary Fusion with Ligand Binding Domain Castration Is Crucial in Rarg -Driven APL and Render Unresponsive to ATRA Via Allosteric Disability Mechanism

Xiaosu Zhou, Xue Chen, Ya-Zhen Qin, Zhanglin Zhang, Jiaqi Chen, Lijun Wen, Panxiang Cao, Yingchang Mi, Wei Wang, Huanling Wu, Guangsen Zhang, Ji Li, Zhifen Zhang, Jian Zhang, Zhan Su, Fang Wang, Yang Zhang, Xiaoli Ma, Jiancheng Fang, Ping Wu, Tong Wang, Ruijie Tang, Wanting He, Yang Zhao, Ran Gao, Honghu Zhu, Siyuan Liu, David Jin, Xian Zhang, Leping Zhang, Peihua Lu, Suning Chen, Hongxing Liu
Journal: Blood
Blood (2023) 142 (Supplement 1): 2949.
https://doi.org/10.1182/blood-2023-185483
Published: 2023
Journal Articles

Outcome and Molecular Measurable Residual Disease Monitoring in Adult B-Cell Acute Lymphoblastic Leukemia Patients with MEF2D Fusions

Kai Sun, Wen-Min Chen, Xu Wang, Xiao-Su Zhao, Ling-Di Li, Yue Hao, Jun Wang, Nan Xu, Hao Jiang, Lan-Ping Xu, Yu Wang, Xiao-Hui Zhang, Qian Jiang, Xiao Jun Huang, Ya-Zhen Qin
Journal: Blood
Blood (2022) 140 (Supplement 1): 11864–11865.
https://doi.org/10.1182/blood-2022-159866
Published: 2022
Journal Articles

A Five-Year Follow-up on Safety and Efficacy of Olverembatinib (HQP1351), a Novel Third-Generation BCR-ABL Tyrosine Kinase Inhibitor (TKI), in Patients with TKI-Resistant Chronic Myeloid Leukemia (CML) in China

Qian Jiang, Zongru Li, Ya-Zhen Qin, Ting Zhao, Bingcheng Liu, Zi Chen, Qian Niu, Lichuang Men, Hengbang Wang, Dajun Yang, Yifan Zhai, Xiao-Jun Huang
Journal: Blood
Blood (2022) 140 (Supplement 1): 198–199.
https://doi.org/10.1182/blood-2022-170868
Published: 2022
Journal Articles

Cancer-Related Gene Mutations Drive Resistance to the Third-Generation Tyrosine Kinase Inhibitor Therapy in Chronic Myeloid Leukaemia

Xiaoshuai Zhang, Zongru Li, Ya-Zhen Qin, Robert Peter Gale, Yueyun Lai, Hongxia Shi, Xiao Jun Huang, Qian Jiang
Journal: Blood
Blood (2022) 140 (Supplement 1): 9611–9613.
https://doi.org/10.1182/blood-2022-169397
Published: 2022
Journal Articles

ATRA Could Correct the Defective S1P-Mediated Cytoskeletal Reorganization in Proplatelet Formation of ITP

Qiu-Sha Huang, Jing Xue, Chen-Cong Wang, Ya-Zhen Qin, Lan-Ping Xu, Kaiyan Liu, Xiao-Jun Huang, MD, Xiao-Hui Zhang
Journal: Blood
Blood (2019) 134 (Supplement_1): 218.
https://doi.org/10.1182/blood-2019-126384
Published: 2019
Journal Articles

Osteoclast Stimulatory Transmembrane Protein ( OCSTAMP ) mRNA Levels and Clinical Variables in Persons with Plasma Cell Myeloma

Ya-Lan Zhou, MD, Jin Lu, Robert Peter Gale, Shen-Miao Yang, Li-Xin Wu, Jin-Lan Li, Ya-Zhen Qin, Yan-Rong Liu, Hao Jiang, Qian Jiang, MD, Xiaohui Zhang, MD, Lan-Ping Xu, Kai-Yan Liu, Xiao-Jun Huang, Guorui Ruan
Journal: Blood
Blood (2018) 132 (Supplement 1): 5264.
https://doi.org/10.1182/blood-2018-99-116883
Published: 2018
Journal Articles

Interferon May Help Control the Recurrence of Chronic Myeloid Leukemia after Discontinuation of Tyrosine Kinase Inhibitor

Jun Kong, MD, Xiao-Hong Liu, Ya-Zhen Qin, Hong-Xia Shi, Yue-Yun Lai, Xiao-Jun Huang, Hao Jiang
Journal: Blood
Blood (2018) 132 (Supplement 1): 4270.
https://doi.org/10.1182/blood-2018-99-119063
Published: 2018
Journal Articles

Oral arsenic and all- trans retinoic acid for high-risk acute promyelocytic leukemia

Clinical Trials & Observations
Hong-Hu Zhu, Yan-Rong Liu, Jin-Song Jia, Ya-Zhen Qin, Xiao-Su Zhao, Yue-Yun Lai
Journal: Blood
Blood (2018) 131 (26): 2987–2989.
https://doi.org/10.1182/blood-2018-02-834051
Published: 2018
Includes: Supplemental data
Journal Articles

Assessment of Standardization and International Scale (IS) Alignment Efforts of BCR-ABL1 Testing By the Chinese CML Alliance in an International External Quality Assessment Program

Ya-Zhen Qin, Stuart Scott, Dao-Xin Ma, Jian-Nong Cen, Cong Han, Min Xiao, MD PhD, Jordan Clark, Peng Zhao, Biao Yin, Annie Tapley, Debbie Travis, Liam Whitby, David Barnett, Xiao-Jun Huang, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2890.
https://doi.org/10.1182/blood.V130.Suppl_1.2890.2890
Published: 2017
Journal Articles

Comparison of the Outcome between Newly Diagnosed Patients in the Accelerated Phase and Chronic Phase with Chronic Myeloid Leukemia Treated with Frontline Tyrosine Kinase Inhibitors

Qian Jiang, MD, Lu Yu, MD, Ya-Zhen Qin, Yue-Yun Lai, Xiao-Jun Huang, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2876.
https://doi.org/10.1182/blood.V130.Suppl_1.2876.2876
Published: 2017
Journal Articles

Clinical Features and Early Effect in EVI1 Positive Acute Myeloid Lleukemia

Wenbing Duan, Lizhong Gong, Jinsong Jia, Honghu Zhu, MD, Xiaosu Zhao, Qian Jiang, PhD, Ting Zhao, Ya-Zhen Qin, Xiaojun Huang, MD, Hao Jiang, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5026.
https://doi.org/10.1182/blood.V130.Suppl_1.5026.5026
Published: 2017
Journal Articles

Mutation Topology of Adult B-Cell Acute Lymphoblastic Leukaemia

Li-Xin Wu, Run-Qing Lu, Kai-Yan Liu, Robert Peter Gale, MD ScD, PhD, Qi Zheng, Jiao Zhou, Jin-Lan Li, Shu-Juan Wang, Hao Jiang, MD, Qian Jiang, MD, Bin Jiang, Xiao-Hui Zhang, MD, Lan-Ping Xu, Yue Wang, Cheng-Li Song, Ya-Zhen Qin, Yan-Rong Liu, Xiao-Jun Huang, MD, Guo-Rui Ruan
Journal: Blood
Blood (2017) 130 (Supplement 1): 3986.
https://doi.org/10.1182/blood.V130.Suppl_1.3986.3986
Published: 2017
Journal Articles

C-KIT- Mutated t(8;21)AML Patients with >3log Reduction of MRD Conferred a Very High Relapse and Need HSCT to Improve Outcome

Hong-Hu Zhu, Ya-Zhen Qin, Lan-Ping Xu, Qian Jiang, MD, Xiao-Hui Zhang, Hao Jiang, MD, Xiao-Jun Huang
Journal: Blood
Blood (2016) 128 (22): 1620.
https://doi.org/10.1182/blood.V128.22.1620.1620
Published: 2016
Journal Articles

Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: To Allogeneic Stem Cell Transplantation or Not? a Single Center Experience

xiao-Jun Huang, MD, Jing Wang, MD, Qian Jiang, MD, Huan Chen, Lanping Xu, Xiao-Hui Zhang, Ya-Zhen Qin, Hao Jiang, MD, Jin Lu, Kai-Yan Liu, Bin Jiang
Journal: Blood
Blood (2016) 128 (22): 2308.
https://doi.org/10.1182/blood.V128.22.2308.2308
Published: 2016
Journal Articles

Overexpression of Cysteine and Glycine-Rich Protein 2 in Bone Marrow As a Novel Biomarker in Adult B-Cell Acute Lymphoblastic Leukemia

Shu-Juan Wang, Wei-Min Wang, Wen-Yi Lu, Ya-Zhen Qin, Yue-Yun Lai, Yan-Rong Liu, Xiao-Jun Huang, Kai-Yan Liu, Guo-Rui Ruan
Journal: Blood
Blood (2016) 128 (22): 5271.
https://doi.org/10.1182/blood.V128.22.5271.5271
Published: 2016
Journal Articles

Janus Kinase Inhibition By Ruxolitinib Combined with Nilotinib Has Superior Anti-Leukemia Propagating Cells Effect in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Yuan Kong, MD PhD, Yi-Lin Wu, Yang Song, Min-Min Shi, Ya-Zhen Qin, Yue-Yun Lai, Hao Jiang, MD, Qian Jiang, Xiao-Jun Huang
Journal: Blood
Blood (2016) 128 (22): 4023.
https://doi.org/10.1182/blood.V128.22.4023.4023
Published: 2016
Journal Articles

Prevalence and Prognostic Significance of c-KIT Mutations in Core Binding Factor Acute Myeloid Leukemia: A Comprehensive Large-Scale Study from a Single Chinese Center

Ya-Zhen Qin, Honghu Zhu, Qian Jiang, Hao Jiang, Le-Ping Zhang, Jin-Lan Li, Ling-Di Li, Yan-Rong Liu, Yue-Yun Lai, Hong-Xia Shi, Bin Jiang, MD, Xiao-Jun Huang, MDPhD
Journal: Blood
Blood (2014) 124 (21): 1000.
https://doi.org/10.1182/blood.V124.21.1000.1000
Published: 2014