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Journal Articles

Therapeutic Doses of Recombinant FVIIa in Hemophilia Generates Thrombin in Platelet-Dependent and -Independent Manner

Shiva Keshava Gaddam Bala Krishna, PhD, Usha Pendurthi, PhD, L. Vijaya Mohan Rao, PhD

Blood (2019) 134 (Supplement_1): 1136.

https://doi.org/10.1182/blood-2019-128474

Published: 2019

Journal Articles

A Lipid Peroxidation Product, 4-Hydroxy-2-Nonenal, Triggers Intravascular Coagulation and Inflammation through Generation of Tissue Factor-Positive Microvesicles

Shabbir Ansari, PhD, Shiva Keshava Gaddam Bala Krishna, PhD, Usha R. Pendurthi, PhD, L. Vijaya Mohan Rao, PhD

Blood (2019) 134 (Supplement_1): 2383.

https://doi.org/10.1182/blood-2019-124498

Published: 2019

Journal Articles

Role of Protease Exosites for In Vivo Hemostatic Activity and Clearance of FIX

Pamela Westmark, PhD, John Sheehan, MD

Blood (2018) 132 (Supplement 1): 1166.

https://doi.org/10.1182/blood-2018-99-120212

Published: 2018

Journal Articles

Preclinical Evaluation of an Engineered AAV Capsid in Non-Human Primates for the Treatment of Haemophilia B

Allison Dane, PhD, Jenny McIntosh, Doyoung Lee, PhD, Rose Sheridan, Mark Maginn, Romuald Corbau, PhD, Andrew M. Davidoff, MD, Amit C Nathwani, MD PhD

Blood (2018) 132 (Supplement 1): 2197.

https://doi.org/10.1182/blood-2018-99-117969

Published: 2018

Journal Articles

Interfering with Protein Z Dependent Inhibition of Factor Xa Improves Coagulation in Hemophilia

George J. Broze, Jr., MD, Thomas James Girard, Nina M Lasky

Blood (2017) 130 (Supplement 1): 1057.

https://doi.org/10.1182/blood.V130.Suppl_1.1057.1057

Published: 2017

Journal Articles

Genetic Fusion to Factor XIII B-Subunit Improves the Pharmacokinetic Properties of Factor IX

Sandra Le Quellec, MD, Nathalie Enjolras, PhD, Jean-Claude Bordet, Vladmir Jacqueline, Claude Negrier, MD, Yesim Dargaud, MD PhD

Blood (2017) 130 (Supplement 1): 2339.

https://doi.org/10.1182/blood.V130.Suppl_1.2339.2339

Published: 2017

Journal Articles

Murine Studies to Test the Efficacy of Platelet Transfusions in the Management of Platelet Function Disorders

Raymond Piatt, BS, Robert Hugh Lee, PhD, David Paul, PhD, Wolfgang Bergmeier, PhD

Blood (2017) 130 (Supplement 1): 1123.

https://doi.org/10.1182/blood.V130.Suppl_1.1123.1123

Published: 2017

Journal Articles

Factor VIIa Interaction with Endothelial Cell Protein C Receptor: Its Role in Hemostatic Effect of rFVIIa in Treating Hemophilia

Shiva Keshava, PhD, Jagan Sundaram, PhD, Anuradha Rajulapati, M.S., Charles T. Esmon, PhD, Usha R. Pendurthi, PhD, L. Vijaya Mohan Rao, PhD

Blood (2016) 128 (22): 562.

https://doi.org/10.1182/blood.V128.22.562.562

Published: 2016

Journal Articles

Bleeding in Factor XI Deficient Mice

Cihan Ay, MD, Yohei Hisada, PhD, Brian C. Cooley, PhD, Nigel Mackman, PhD

Blood (2016) 128 (22): 3766.

https://doi.org/10.1182/blood.V128.22.3766.3766

Published: 2016

Journal Articles

Novel Class of Direct Thrombin Inhibitors Prevent Thrombosis By Inhibiting Fibrinogen Cleavage While Preserving Platelet Function

Mohan Sivaraja, PhD, Sivan Sizikov, PhD, Nichole Sandoval, Kenneth Lin, PhD, Lev Igoudin, Subhadra Dash, MSc, Chengpei Xu, MD PhD, Daniel Clemens, PhD, Angels Estiarte, PhD, Timothy Shiau, PhD, Kevin Short, PhD, David Williams, PhD, Anirban Datta, PhD, David Kita, PhD

Blood (2016) 128 (22): 3834.

https://doi.org/10.1182/blood.V128.22.3834.3834

Published: 2016

Journal Articles

Hemophilia a Clots Generated with Recombinant Factor VIIa Differed in Structure and Composition from Those Formed with Factor VIII

Lilley Leong, Irina N. Chernysh, Yifan Xu, Cornell Mallari, Billy Wong, Derek Sim, Adam Cuker, MD MS, Joseph Marturano, Thomas Lowery, Katalin Kauser, John W. Weisel

Blood (2016) 128 (22): 3798.

https://doi.org/10.1182/blood.V128.22.3798.3798

Published: 2016

Journal Articles

Prophylactic efficacy of BeneFIX vs Alprolix in hemophilia B mice

Brian Cooley, William Funkhouser, Dougald Monroe, Ashley Ezzell, David M. Mann, Feng-Chang Lin, Paul E. Monahan, Darrel W. Stafford

Blood (2016) 128 (2): 286–292.

https://doi.org/10.1182/blood-2016-01-696104

Published: 2016

Journal Articles

Role of Red Cells in Thrombosis and Hemostasis

John W. Weisel, PhD

Blood (2015) 126 (23): SCI-39.

https://doi.org/10.1182/blood.V126.23.SCI-39.SCI-39

Published: 2015

Journal Articles

Novel Gene Therapy Strategy for Hemophilia a By Hydrodynamic Gene Delivery Combined with Non-Viral Piggybac Transposon Vector in Canine Model

Masashi Noda, DVM, Hideto Matsui, MD PhD, Yasunori Matsunari, MD, Sunao Ochi, DVM, Midori Shima, MD PhD, Yasushi Fukuoka, Takeshi Sato, MD, Hiroshi Anai, MD PhD, Kimihiko Kichikawa, MD PhD, Masanari Nakayama, DVM, PhD, Akitsu Hotta, PhD, Mitsuhiko Sugimoto, MD PhD

Blood (2015) 126 (23): 4419.

https://doi.org/10.1182/blood.V126.23.4419.4419

Published: 2015

Journal Articles

At Equal Doses FIXFc (Alprolix) Is Not Significanly Better in a Saphenous Vein Bleeding Model Than Recombinant FIX (BeneFix) Seven Days Post-Infusion

Brian Cooley, PhD, David M Mann, PhD, Dougald Monroe, PhD, Feng-Chang Lin, Paul E. Monahan, MD, Darrel W. Stafford, PhD

Blood (2015) 126 (23): 3490.

https://doi.org/10.1182/blood.V126.23.3490.3490

Published: 2015

Journal Articles

Pharmacological Concentrations of Recombinant Factor VIIa Restores Hemostasis in Acquired Hemophilia Primarily Independent of Tissue Factor

Shiva Keshava, PhD, Jagan Sundaram, PhD, Anuradha Rajulapati, M.S., Usha R Pendurthi, PhD, L. Vijaya Mohan Rao, PhD

Blood (2015) 126 (23): 293.

https://doi.org/10.1182/blood.V126.23.293.293

Published: 2015

Journal Articles

Novel Mouse Hemostasis Model for Real-Time Determination of Bleeding Time and Hemostatic Plug Composition

Wolfgang Bergmeier, PhD, Raymond Piatt, Brian G. Petrich, PhD, Dougald Monroe, PhD, Nigel Mackman, PhD, Todd M Getz, PhD

Blood (2014) 124 (21): 4177.

https://doi.org/10.1182/blood.V124.21.4177.4177

Published: 2014

Journal Articles

A Subcutaneously Administered RNAi Therapeutic (ALN-AT3) Targeting Antithrombin for Treatment of Hemophilia: Interim Phase 1 Study Results in Healthy Volunteers and Patients with Hemophilia a or B

Benny Sorensen, MD PhD, Tim Mant, MD, Akin Akinc, PhD, Amy Simon, MD, Lauren Melton, Christian Lynam, Andrew Strahs, PhD, Alfica Sehgal, PhD, Renta Hutabarat, PhD, Prasoon Chaturvedi, PhD, Scott Barros, PhD, Akshay Vaishnaw, MD PhD, Aln-AT Investigators

Blood (2014) 124 (21): 693.

https://doi.org/10.1182/blood.V124.21.693.693

Published: 2014

Journal Articles

An Antibody Targeted To The Anionic Region Of Human Protease Activated Receptor 4 Inhibits Thrombosis Without Influencing Bleeding

Michele M. Mumaw, Maria de la Fuente, Amal Arachiche, PhD, Daniel N. Nobel, Marvin T. Nieman, PhD

Blood (2013) 122 (21): 2376.

https://doi.org/10.1182/blood.V122.21.2376.2376

Published: 2013

Journal Articles

Reversal Of Dabigatran Anticoagulation By a 4-Factor Prothrombin Complex Concentrate: Correlation Between Effects On Parameters Of Thrombin Generation and Hemostatic Effect In Vivo

Maureane Hoffman, MD, PhD, Zoya Volovyk, PhD, Dougald Monroe, PhD

Blood (2013) 122 (21): 3643.

https://doi.org/10.1182/blood.V122.21.3643.3643

Published: 2013

NARROW

Therapeutic Doses of Recombinant FVIIa in Hemophilia Generates Thrombin in Platelet-Dependent and -Independent Manner

A Lipid Peroxidation Product, 4-Hydroxy-2-Nonenal, Triggers Intravascular Coagulation and Inflammation through Generation of Tissue Factor-Positive Microvesicles

Role of Protease Exosites for In Vivo Hemostatic Activity and Clearance of FIX

Preclinical Evaluation of an Engineered AAV Capsid in Non-Human Primates for the Treatment of Haemophilia B

Interfering with Protein Z Dependent Inhibition of Factor Xa Improves Coagulation in Hemophilia

Genetic Fusion to Factor XIII B-Subunit Improves the Pharmacokinetic Properties of Factor IX

Murine Studies to Test the Efficacy of Platelet Transfusions in the Management of Platelet Function Disorders

Factor VIIa Interaction with Endothelial Cell Protein C Receptor: Its Role in Hemostatic Effect of rFVIIa in Treating Hemophilia

Bleeding in Factor XI Deficient Mice

Novel Class of Direct Thrombin Inhibitors Prevent Thrombosis By Inhibiting Fibrinogen Cleavage While Preserving Platelet Function

Hemophilia a Clots Generated with Recombinant Factor VIIa Differed in Structure and Composition from Those Formed with Factor VIII

Prophylactic efficacy of BeneFIX vs Alprolix in hemophilia B mice

Role of Red Cells in Thrombosis and Hemostasis

Novel Gene Therapy Strategy for Hemophilia a By Hydrodynamic Gene Delivery Combined with Non-Viral Piggybac Transposon Vector in Canine Model

At Equal Doses FIXFc (Alprolix) Is Not Significanly Better in a Saphenous Vein Bleeding Model Than Recombinant FIX (BeneFix) Seven Days Post-Infusion

Pharmacological Concentrations of Recombinant Factor VIIa Restores Hemostasis in Acquired Hemophilia Primarily Independent of Tissue Factor

Novel Mouse Hemostasis Model for Real-Time Determination of Bleeding Time and Hemostatic Plug Composition

A Subcutaneously Administered RNAi Therapeutic (ALN-AT3) Targeting Antithrombin for Treatment of Hemophilia: Interim Phase 1 Study Results in Healthy Volunteers and Patients with Hemophilia a or B

An Antibody Targeted To The Anionic Region Of Human Protease Activated Receptor 4 Inhibits Thrombosis Without Influencing Bleeding

Reversal Of Dabigatran Anticoagulation By a 4-Factor Prothrombin Complex Concentrate: Correlation Between Effects On Parameters Of Thrombin Generation and Hemostatic Effect In Vivo

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American Society of Hematology

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ASH Publications

American Society of Hematology

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