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Journal Articles

CD45-ADC Plus Janus Kinase (JAK) Inhibitors As Conditioning for MHC-Mismatched Murine Hematopoietic Stem Cell Transplantation Is Associated with Minimal Toxicity and Graft Versus Host Disease

Stephen P. Persaud, MD PhD, Matthew L. Cooper, PhD, Julie K. Ritchey, Michael P. Rettig, PhD, John F. DiPersio, MD PhD

Blood (2019) 134 (Supplement_1): 3200.

https://doi.org/10.1182/blood-2019-123519

Published: 2019

Journal Articles

Antibody Drug Conjugates Targeted to CD45 or CD117 Enable Allogeneic Hematopoietic Stem Cell Transplantation in Animal Models

Rahul Palchaudhuri, PhD, Sharon L. Hyzy, MS, Jennifer L Proctor, BS, Hillary L Adams, MS, Bradley R Pearse, PhD, Ganapathy Sarma, PhD, Sharon Aslanian, MS, Geoff Gillard, PhD, Tahirih L Lamothe, Olga Burenkova, BS, Melissa L. Brooks, BS, Andrew D Gabros, Charlotte F McDonagh, PhD, Anthony E. Boitano, PhD, Michael P. Cooke, PhD

Blood (2018) 132 (Supplement 1): 3324.

https://doi.org/10.1182/blood-2018-99-119432

Published: 2018

Journal Articles

Non-Genotoxic Conditioning Efficiently Depletes Host Hematopoietic Stem Cells and Facilitates Robust Multi-Lineage Engraftment in a Mouse Model of Fanconi Anemia

Meera Srikanthan, MD, Kevin G. Haworth, PhD, Christina M. Ironside, BS, Jerry Chen, Adam J. Hartigan, PhD, Rahul Palchaudhuri, PhD, Anthony E. Boitano, PhD, Michael P. Cooke, PhD, Hans-Peter Kiem, MD PhD

Blood (2018) 132 (Supplement 1): 2041.

https://doi.org/10.1182/blood-2018-99-116851

Published: 2018

Journal Articles

Conditioning for Hematopoietic Stem Cell Transplantation Using Antibody-Drug Conjugate Targeting CD45 Permits Engraftment across Immunologic Barriers

Steve P. Persaud, MD PhD, Matthew L. Cooper, PhD, Michael P. Rettig, PhD, John F. DiPersio, MD PhD

Blood (2018) 132 (Supplement 1): 2035.

https://doi.org/10.1182/blood-2018-99-116894

Published: 2018

Journal Articles

Non-Genotoxic Conditioning for Hematopoietic Stem Cell Transplant Using a Human Antibody Drug Conjugate Targeting C-KIT

Adam J. Hartigan, PhD, Bradley R. Pearse, PhD, Sean M. McDonough, Jennifer L. Proctor, BS, Hillary L. Adams, MS, Molly A. McShea, Megan D. Hoban, Rajiv Panwar, PhD, Sharon L. Hyzy, MS, Kevin A. Goncalves, PhD, Rahul Palchaudhuri, PhD BA, Anthony E. Boitano, PhD, Michael P. Cooke, PhD

Blood (2017) 130 (Supplement 1): 1894.

https://doi.org/10.1182/blood.V130.Suppl_1.1894.1894

Published: 2017

Journal Articles

Novel IL-2Ralpha (CD25)-Binding RNA Aptamer to Target T Regulatory Cells

Suresh Veeramani, DVM, PhD, Sue E Blackwell, MS, William H Thiel, PhD, Paloma H Giangrande, PhD, George J Weiner, MD

Blood (2016) 128 (22): 3697.

https://doi.org/10.1182/blood.V128.22.3697.3697

Published: 2016

Journal Articles

Enhanced Allogeneic Engraftment Achieved Via Prenatal Tolerance Induction and Postnatal Anti-CD45 Immunotoxin Conditioned Hematopoietic Cell Transplantation

Patrick E. McGovern, MD, Agnieszka Czechowicz, MD PhD, Ali Mejaddam, MD, John D. Stratigis, MD, Haiying Li, John Urwin, Lauren E. McClain, MD, Philip W. Zoltick, MD, Alan W. Flake, MD, William H. Peranteau, MD

Blood (2016) 128 (22): 2153.

https://doi.org/10.1182/blood.V128.22.2153.2153

Published: 2016

Journal Articles

Completely Non-Myeloablative/Non-Lymphoablative Conditioning for BMT/HSCT Using Anti-Ckit Immunotoxins

Agnieszka Czechowicz, MD PhD, Rahul Palchaudhuri, PhD, Amelia Scheck, BS, Jonathan Hoggatt, PhD, Borja Saez, PhD, David T. Scadden, MD, Derrick J. Rossi, PhD

Blood (2016) 128 (22): 493.

https://doi.org/10.1182/blood.V128.22.493.493

Published: 2016

Journal Articles

Immunotoxin Enables Non-Genotoxic Conditioning for Hematopoietic Stem Cell Transplantation

Rahul Palchaudhuri, PhD, Borja Saez, PhD, Jonathan Hoggatt, PhD, Amir Schajnovitz, David B. Sykes, MD PhD, Michael K Mansour, MD PhD, David T. Scadden, MD

Blood (2015) 126 (23): 32.

https://doi.org/10.1182/blood.V126.23.32.32

Published: 2015

Journal Articles

Benzene Induces Hematotoxicity Via Acetyltransferase p300 Inhibition-Mediated Autophagy

Shanhu Qian, Shenghui Zhang, Yifen Shi, Jiaqi Li, Junqing Wu, Gang Hu, Lan Sun, Yixiang Han, Kang Yu, MD

Blood (2015) 126 (23): 4759.

https://doi.org/10.1182/blood.V126.23.4759.4759

Published: 2015

Journal Articles

Decreasing the Humoral Response to Factor VIII By Targeted Deletion of Factor VIII - Specific B Cells

Rebecca C. Markovitz, John F. Healey, W. Hunter Baldwin, Ernest T. Parker, Shannon L. Meeks, Pete Lollar

Blood (2014) 124 (21): 238.

https://doi.org/10.1182/blood.V124.21.238.238

Published: 2014

Journal Articles

The HB22.7 Anti-CD22 Monoclonal Antibody Is an Effective Platform for CD22-Targeted Antibody Drug Conjugates for Treatment of Lymphoma and Acute Lymphoblastic Leukemia

Soames F. Boyle, MD, Jason Kato, PhD, Robert O'Donnell, MD, PhD, Joseph Tuscano, MD

Blood (2012) 120 (21): 1653.

https://doi.org/10.1182/blood.V120.21.1653.1653

Published: 2012

Journal Articles

Selective deletion of antigen-specific CD8 + T cells by MHC class I tetramers coupled to the type I ribosome-inactivating protein saporin

Paul R. Hess, Carie Barnes, Matthew D. Woolard, Michael D. L. Johnson, John M. Cullen, Edward J. Collins, Jeffrey A. Frelinger

Blood (2006) 109 (8): 3300–3307.

https://doi.org/10.1182/blood-2006-06-028001

Published: 2006

Journal Articles

Antibody Dependent Cellular Cytotoxicity (ADCC) Augmentation of Immunotoxin Activity in SCID-HSB-2 Mice Is Adoptively Transferable to NOD/SCID-HSB-2 Mice.

David J. Flavell, PhD, FRCPath, Sopsamorn U. Flavell, PhD

Blood (2006) 108 (11): 1837.

https://doi.org/10.1182/blood.V108.11.1837.1837

Published: 2006

Journal Articles

Effective Induction of Apoptosis by Mistletoe Plant Extracts in an Acute Lymphoblastic Leukemia Model.

Georg Seifert, MD, Patrick Jesse, MD, Aram Prokop, PhD, Tobias Reindl, MD, Stephan Lobitz, MD, Alfred Laengler, MD, Holger N. Lode, PhD, Guenter Henze, PhD

Blood (2006) 108 (11): 1880.

https://doi.org/10.1182/blood.V108.11.1880.1880

Published: 2006

Journal Articles

Co-Operativity between Antibody-Dependent Cellular Cytotoxicity (ADCC) and Immunotoxin-Mediated Killing of Human T-ALL Cells in a SCID Mouse Model: Simultaneous Delivery of Saporin Via CD7 and ADCC Via CD38 Is No Better Than the Simultaneous Delivery of Each Against Only CD7.

David J. Flavell, PhD, FRCPath, Sopsamorn U. Flavell, PhD

Blood (2006) 108 (11): 4517.

https://doi.org/10.1182/blood.V108.11.4517.4517

Published: 2006

NARROW

CD45-ADC Plus Janus Kinase (JAK) Inhibitors As Conditioning for MHC-Mismatched Murine Hematopoietic Stem Cell Transplantation Is Associated with Minimal Toxicity and Graft Versus Host Disease

Antibody Drug Conjugates Targeted to CD45 or CD117 Enable Allogeneic Hematopoietic Stem Cell Transplantation in Animal Models

Non-Genotoxic Conditioning Efficiently Depletes Host Hematopoietic Stem Cells and Facilitates Robust Multi-Lineage Engraftment in a Mouse Model of Fanconi Anemia

Conditioning for Hematopoietic Stem Cell Transplantation Using Antibody-Drug Conjugate Targeting CD45 Permits Engraftment across Immunologic Barriers

Non-Genotoxic Conditioning for Hematopoietic Stem Cell Transplant Using a Human Antibody Drug Conjugate Targeting C-KIT

Novel IL-2Ralpha (CD25)-Binding RNA Aptamer to Target T Regulatory Cells

Enhanced Allogeneic Engraftment Achieved Via Prenatal Tolerance Induction and Postnatal Anti-CD45 Immunotoxin Conditioned Hematopoietic Cell Transplantation

Completely Non-Myeloablative/Non-Lymphoablative Conditioning for BMT/HSCT Using Anti-Ckit Immunotoxins

Immunotoxin Enables Non-Genotoxic Conditioning for Hematopoietic Stem Cell Transplantation

Benzene Induces Hematotoxicity Via Acetyltransferase p300 Inhibition-Mediated Autophagy

Decreasing the Humoral Response to Factor VIII By Targeted Deletion of Factor VIII - Specific B Cells

The HB22.7 Anti-CD22 Monoclonal Antibody Is an Effective Platform for CD22-Targeted Antibody Drug Conjugates for Treatment of Lymphoma and Acute Lymphoblastic Leukemia

Selective deletion of antigen-specific CD8 + T cells by MHC class I tetramers coupled to the type I ribosome-inactivating protein saporin

Antibody Dependent Cellular Cytotoxicity (ADCC) Augmentation of Immunotoxin Activity in SCID-HSB-2 Mice Is Adoptively Transferable to NOD/SCID-HSB-2 Mice.

Effective Induction of Apoptosis by Mistletoe Plant Extracts in an Acute Lymphoblastic Leukemia Model.

Co-Operativity between Antibody-Dependent Cellular Cytotoxicity (ADCC) and Immunotoxin-Mediated Killing of Human T-ALL Cells in a SCID Mouse Model: Simultaneous Delivery of Saporin Via CD7 and ADCC Via CD38 Is No Better Than the Simultaneous Delivery of Each Against Only CD7.

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American Society of Hematology

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American Society of Hematology

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