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Journal Articles

Conformational activation and inhibition of von Willebrand factor by targeting its autoinhibitory module

Nicholas A. Arce, Zoe Markham-Lee, Qian Liang, Shabir Najmudin, Emily R. Legan, Gabrielle Dean, Ally J. Su, Moriah S. Wilson, Robert F. Sidonio, Pete Lollar, Jonas Emsley, Renhao Li

Blood (2024) 143 (19): 1992–2004.

https://doi.org/10.1182/blood.2023022038

Published: 2024

Includes: Supplemental data

Journal Articles

Structure of coagulation factor VIII bound to a patient-derived anti–C1 domain antibody inhibitor

Kenneth C. Childers, Nathan G. Avery, Kevin A. Estrada Alamo, Omar Davulcu, Rose Marie Haynes, Pete Lollar, Christopher B. Doering, Carmen H. Coxon, P. Clint Spiegel, Jr.

Blood (2023) 142 (2): 197–201.

https://doi.org/10.1182/blood.2023020181

Published: 2023

Includes: Supplemental data

Journal Articles

Type 2B von Willebrand disease mutations differentially perturb autoinhibition of the A1 domain

Emily R. Legan, Yi Liu, Nicholas A. Arce, Ernest T. Parker, Pete Lollar, X. Frank Zhang, Renhao Li

Blood (2023) 141 (10): 1221–1232.

https://doi.org/10.1182/blood.2022017239

Published: 2023

Includes: Supplemental data

Journal Articles

Nonhuman glycans can regulate anti–factor VIII antibody formation in mice

Connie M. Arthur, Patricia E. Zerra, Sooncheon Shin, Jianmei Wang, Xeuzheng Song, Christopher B. Doering, Pete Lollar, Shannon Meeks, Sean R. Stowell

Blood (2022) 139 (9): 1312–1317.

https://doi.org/10.1182/blood.2020009210

Published: 2022

Includes: Supplemental data

Journal Articles

Structure of blood coagulation factor VIII in complex with an anti–C1 domain pathogenic antibody inhibitor

Joseph S. Gish, Lexi Jarvis, Kenneth C. Childers, Shaun C. Peters, Connor S. Garrels, Ian W. Smith, H. Trent Spencer, Christopher B. Doering, Pete Lollar, P. Clint Spiegel, Jr

Blood (2021) 137 (21): 2981–2986.

https://doi.org/10.1182/blood.2020008940

Published: 2021

Includes: Supplemental data

Journal Articles

Marginal zone B cells are critical to factor VIII inhibitor formation in mice with hemophilia A

Patricia E. Zerra, Courtney Cox, W. Hunter Baldwin, Seema R. Patel, Connie M. Arthur, Pete Lollar, Shannon L. Meeks, Sean R. Stowell

Blood (2017) 130 (23): 2559–2568.

https://doi.org/10.1182/blood-2017-05-782912

Published: 2017

Includes: Supplemental data

Journal Articles

Frequency and epitope specificity of anti–factor VIII C1 domain antibodies in acquired and congenital hemophilia A

Joerg Kahle, Aleksander Orlowski, Diana Stichel, John F. Healey, Ernest T. Parker, Marc Jacquemin, Manuela Krause, Andreas Tiede, Dirk Schwabe, Pete Lollar, Christoph Königs

Blood (2017) 130 (6): 808–816.

https://doi.org/10.1182/blood-2016-11-751347

Published: 2017

Includes: Supplemental data

Journal Articles

Platelet Membranes and Activation Pathway Determine Inhibitory Activity of Anti-Factor VIII C2 Domain Antibodies

Madhumouli Chatterjee, PhD, Shannon L. Meeks, MD, Valerie Anne Novakovic, MS, Pete Lollar, MD, Gary E. Gilbert, MD

Blood (2016) 128 (22): 2567.

https://doi.org/10.1182/blood.V128.22.2567.2567

Published: 2016

Journal Articles

A Short N-Terminal Fragment in Front of the A1 Domain of Von Willebrand Factor Prevents the A1 from Binding the Platelet By Masking a Region Clustered By Type 2B VWD Mutations

Wei Deng, PhD, Yingchun Wang, PhD, Pete Lollar, MD, Renhao Li, PhD

Blood (2016) 128 (22): 553.

https://doi.org/10.1182/blood.V128.22.553.553

Published: 2016

Journal Articles

Characterization of Factor VIII Immune Complexes By Analytical Ultracentrifugation

Pete Lollar, MD, Ernest T. Parker, John F. Healey, Christopher B. Doering, PhD

Blood (2016) 128 (22): 3787.

https://doi.org/10.1182/blood.V128.22.3787.3787

Published: 2016

Journal Articles

Factor VIII C2 Domain Epitopes Recognized By Classical and Non-Classical Anti-C2 Domain Monoclonal Antibodies Help Mediate FVIII Uptake By Dendritic Cells

Glaivy Batsuli, MD, Wallace Hunter Baldwin, BS, John F Healey, BS, Ernest T Parker, BS, Courtney Cox, MSc, Pete Lollar, MD, Shannon L. Meeks, MD

Blood (2016) 128 (22): 3762.

https://doi.org/10.1182/blood.V128.22.3762.3762

Published: 2016

Journal Articles

High-affinity, noninhibitory pathogenic C1 domain antibodies are present in patients with hemophilia A and inhibitors

Glaivy Batsuli, Wei Deng, John F. Healey, Ernest T. Parker, W. Hunter Baldwin, Courtney Cox, Brenda Nguyen, Joerg Kahle, Christoph Königs, Renhao Li, Pete Lollar, Shannon L. Meeks

Blood (2016) 128 (16): 2055–2067.

https://doi.org/10.1182/blood-2016-02-701805

Published: 2016

Includes: Supplemental data

Journal Articles

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Pete Lollar

Blood (2016) 128 (2): 156–157.

https://doi.org/10.1182/blood-2016-05-713040

Published: 2016

Journal Articles

Anti-C1 Domain Antibodies Are Pathogenic in a Murine Tail Snip Model Despite Low Inhibitor Titers

Glaivy Batsuli, MD, John Healey, BS, Ernest Parker, BS, Wallace Hunter Baldwin, BS, Courtney Cox, MSc, Brenda Nguyen, BS, Pete Lollar, MD, Shannon L. Meeks, MD

Blood (2015) 126 (23): 1066.

https://doi.org/10.1182/blood.V126.23.1066.1066

Published: 2015

Journal Articles

Decreasing the Humoral Response to Factor VIII By Targeted Deletion of Factor VIII - Specific B Cells

Rebecca C. Markovitz, John F. Healey, W. Hunter Baldwin, Ernest T. Parker, Shannon L. Meeks, Pete Lollar

Blood (2014) 124 (21): 238.

https://doi.org/10.1182/blood.V124.21.238.238

Published: 2014

Journal Articles

Anti-Factor VIII C1 Domain Antibodies Are Present in the Plasmas of Patients with Hemophilia and Inhibitors

Glaivy Batsuli, MD, Courtney Cox, M.S., John F. Healey, B.S., Pete Lollar, MD, Shannon L Meeks, MD

Blood (2014) 124 (21): 1482.

https://doi.org/10.1182/blood.V124.21.1482.1482

Published: 2014

Journal Articles

High-resolution mapping of epitopes on the C2 domain of factor VIII by analysis of point mutants using surface plasmon resonance

Phuong-Cac T. Nguyen, Kenneth B. Lewis, Ruth A. Ettinger, Jason T. Schuman, Jasper C. Lin, John F. Healey, Shannon L. Meeks, Pete Lollar, Kathleen P. Pratt

Blood (2014) 123 (17): 2732–2739.

https://doi.org/10.1182/blood-2013-09-527275

Published: 2014

Includes: Supplemental data

Journal Articles

Structure of the factor VIII C2 domain in a ternary complex with 2 inhibitor antibodies reveals classical and nonclassical epitopes

Justin D. Walter, Rachel A. Werther, Caileen M. Brison, Rebecca K. Cragerud, John F. Healey, Shannon L. Meeks, Pete Lollar, P. Clint Spiegel, Jr

Blood (2013) 122 (26): 4270–4278.

https://doi.org/10.1182/blood-2013-08-519124

Published: 2013

Includes: Supplemental data

Journal Articles

Anti-FVIII Autoantibodies Share Similar Characteristics In Acquired Hemophilia A Patients With and Without An Associated Disease

Joerg Kahle, PhD, Christoph Königs, MD, PhD, Anja Naumann, Thomas Klingebiel, MD, John F Healey, Ernest T Parker, B.A., Pete Lollar, MD, Dirk Schwabe, MD, Manuela Krause, MD

Blood (2013) 122 (21): 1110.

https://doi.org/10.1182/blood.V122.21.1110.1110

Published: 2013

Journal Articles

The diversity of the immune response to the A2 domain of human factor VIII

Rebecca C. Markovitz, John F. Healey, Ernest T. Parker, Shannon L. Meeks, Pete Lollar

Blood (2013) 121 (14): 2785–2795.

https://doi.org/10.1182/blood-2012-09-456582

Published: 2013

Includes: Supplemental data

NARROW

Conformational activation and inhibition of von Willebrand factor by targeting its autoinhibitory module

Structure of coagulation factor VIII bound to a patient-derived anti–C1 domain antibody inhibitor

Type 2B von Willebrand disease mutations differentially perturb autoinhibition of the A1 domain

Nonhuman glycans can regulate anti–factor VIII antibody formation in mice

Structure of blood coagulation factor VIII in complex with an anti–C1 domain pathogenic antibody inhibitor

Marginal zone B cells are critical to factor VIII inhibitor formation in mice with hemophilia A

Frequency and epitope specificity of anti–factor VIII C1 domain antibodies in acquired and congenital hemophilia A

Platelet Membranes and Activation Pathway Determine Inhibitory Activity of Anti-Factor VIII C2 Domain Antibodies

A Short N-Terminal Fragment in Front of the A1 Domain of Von Willebrand Factor Prevents the A1 from Binding the Platelet By Masking a Region Clustered By Type 2B VWD Mutations

Characterization of Factor VIII Immune Complexes By Analytical Ultracentrifugation

Factor VIII C2 Domain Epitopes Recognized By Classical and Non-Classical Anti-C2 Domain Monoclonal Antibodies Help Mediate FVIII Uptake By Dendritic Cells

High-affinity, noninhibitory pathogenic C1 domain antibodies are present in patients with hemophilia A and inhibitors

Fill 'er up? Fill what up?

Anti-C1 Domain Antibodies Are Pathogenic in a Murine Tail Snip Model Despite Low Inhibitor Titers

Decreasing the Humoral Response to Factor VIII By Targeted Deletion of Factor VIII - Specific B Cells

Anti-Factor VIII C1 Domain Antibodies Are Present in the Plasmas of Patients with Hemophilia and Inhibitors

High-resolution mapping of epitopes on the C2 domain of factor VIII by analysis of point mutants using surface plasmon resonance

Structure of the factor VIII C2 domain in a ternary complex with 2 inhibitor antibodies reveals classical and nonclassical epitopes

Anti-FVIII Autoantibodies Share Similar Characteristics In Acquired Hemophilia A Patients With and Without An Associated Disease

The diversity of the immune response to the A2 domain of human factor VIII

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American Society of Hematology

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American Society of Hematology

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