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Journal Articles

TGF-β Signaling in Fetal Mesenchymal Progenitor Cells Plays an Essential Role in the Emergence of Bone Marrow Hematopoietic Niches

Grazia Abou Ezzi, PhD, Teerawit Supakorndej, BS, Jingzhu Zhang, BS, Joseph R. Krambs, BS, Hamza Celik, PhD, Daniel C. Link, MD

Blood (2018) 132 (Supplement 1): 3847.

https://doi.org/10.1182/blood-2018-99-117396

Published: 2018

Journal Articles

DLX1 Affects Cell Cycle and Proliferation of Myeloid Leukemia Cells In Vitro and In Vivo

Katerina Rejlova, Miroslava Kardosova, Martina Slamova, Marketa Zaliova, Meritxell Alberich-Jorda, Jan Trka, MD PhD, Julia Starkova

Blood (2016) 128 (22): 1666.

https://doi.org/10.1182/blood.V128.22.1666.1666

Published: 2016

Journal Articles

An Inhibitor of TGF-β Promotes Proliferation of Normal but Not MPN Hematopoietic Cells and Is a Candidate Therapeutic Agent for the Treatment of MPN Patients Carrying JAK2 V617F or Calr pQ365fs Mutations

Anna Rita Migliaccio, PhD, Camelia Iancu-Rubin, PhD, Rona Singer Weinberg, PhD, Ronald Hoffman, MD, Amylou Constance Dueck, PhD, John O. Mascarenhas, MD MS

Blood (2015) 126 (23): 4089.

https://doi.org/10.1182/blood.V126.23.4089.4089

Published: 2015

Journal Articles

Dysregulation of the TGF β Pathway in Induced Pluripotent Stem Cells (iPSCs) Generated from Patients with Diamond Blackfan Anemia (DBA)

Jingping Ge, Marisa Apicella, Jason A. Mills, Loic Garcon, Deborah L. French, PhD, Mitchell J. Weiss, MD PhD, Monica Bessler, MDPhD, Philip J Mason, PhD

Blood (2014) 124 (21): 254.

https://doi.org/10.1182/blood.V124.21.254.254

Published: 2014

Journal Articles

Endothelial Smad4 restrains the transition to hematopoietic progenitors via suppression of ERK activation

Yu Lan, Wenyan He, Zhuan Li, Yu Wang, Jun Wang, Jiao Gao, Weili Wang, Tao Cheng, Bing Liu, Xiao Yang

Blood (2014) 123 (14): 2161–2171.

https://doi.org/10.1182/blood-2013-09-526053

Published: 2014

Includes: Supplemental data

Journal Articles

Epigenetic Dysregulation Of ZNF423 Impedes B-Cell Differentiation and Is Linked To Adverse Outcome Of Childhood B-Precursor ALL

Ann-Christin Puller, MSc, Lena Harder, PhD, Martin Zimmermann, PhD, Carol Stocking, PhD, Martin A. Horstmann, MD

Blood (2013) 122 (21): 3745.

https://doi.org/10.1182/blood.V122.21.3745.3745

Published: 2013

Journal Articles

Human hematopoietic stem/progenitor cells overexpressing Smad4 exhibit impaired reconstitution potential in vivo

Emma Rörby, Matilda Nifelt Hägerström, Ulrika Blank, Göran Karlsson, Stefan Karlsson

Blood (2012) 120 (22): 4343–4351.

https://doi.org/10.1182/blood-2012-02-408658

Published: 2012

Includes: Supplemental data

Journal Articles

MiR-146a Expression Level As a Molecular Marker in Acute Promyleocytic Leukemia

Hua Zhong, Chun Wang, Chen Fangyuan, Lan Xu, Jihua Zhong, HU Jiong

Blood (2012) 120 (21): 4821.

https://doi.org/10.1182/blood.V120.21.4821.4821

Published: 2012

Journal Articles

the miR-99∼125 P olycistrons Promote Leukemogenesis in a Cell-Context Dependent Manner by Shifting the Balance Between TGFβ- and Wnt-Signaling

Stephan Emmrich, Mareike Rasche, Jennifer Schöning, Zhe Li, PhD, Axel Schambach, MD PhD, Dirk Reinhardt, MD, Jan-Henning Klusmann, MD

Blood (2012) 120 (21): 109.

https://doi.org/10.1182/blood.V120.21.109.109

Published: 2012

Journal Articles

Proteomic Profiling of AML Bone Marrow-Derived Mesenchymal Stem Cells (MSC) Reveals Marked Differences From Normal MSC.

Rui-yu Wang, MD, PhD, Yi Hua Qiu, MD, Suk Young Yoo, PhD, Teresa McQueen, BS, Ye Chen, PhD, Zhihong Zeng, MD, Kevin R. Coombes, PhD, Wendy D. Schober, MLT (ASCP), Marina Konopleva, MD, PhD, Steven M. Kornblau, MD, PhD, Michael Andreeff, MD, PhD

Blood (2012) 120 (21): 2355.

https://doi.org/10.1182/blood.V120.21.2355.2355

Published: 2012

Journal Articles

Development and function of murine RORγt + iNKT cells are under TGF-β signaling control

Colin Havenar-Daughton, Shamin Li, Kamel Benlagha, Julien C. Marie

Blood (2012) 119 (15): 3486–3494.

https://doi.org/10.1182/blood-2012-01-401604

Published: 2012

Includes: Supplemental data

Journal Articles

MicroRNA-130a–mediated down-regulation of Smad4 contributes to reduced sensitivity to TGF-β1 stimulation in granulocytic precursors

Mattias Häger, Corinna Cavan Pedersen, Maria Torp Larsen, Mette Klarskov Andersen, Christoffer Hother, Kirsten Grønbæk, Hanne Jarmer, Niels Borregaard, Jack Bernard Cowland

Blood (2011) 118 (25): 6649–6659.

https://doi.org/10.1182/blood-2011-03-339978

Published: 2011

Includes: Supplemental data

Journal Articles

Impaired Reconstitution Potential of TGFβ-Hypersensitive Human Hematopoietic Stem Cells

Emma Rörby, Matilda Nifelt Hägerström, Ulrika Blank, Göran Karlsson, Ph.D., Stefan Karlsson, M.D., Ph.D., Prof.

Blood (2011) 118 (21): 394.

https://doi.org/10.1182/blood.V118.21.394.394

Published: 2011

Journal Articles

Mir-130a-Mediated Downregulation of SMAD4 Contributes to Reduced Sensitivity to TGFβ Stimulation in Promyelocytic Cells,

Mattias Hager, Corinna Cavan Pedersen, Maria Torp Larsen, Mette Klarskov Andersen, MD, Christoffer Hother, MD, Kirsten Grønbæk, MD, DMSc, Hanne Jarmer, Niels Borregaard, Jack B Cowland

Blood (2011) 118 (21): 3383.

https://doi.org/10.1182/blood.V118.21.3383.3383

Published: 2011

Journal Articles

Gata2 Is a Direct Target for Smad-Mediated TGFβ Signaling in Hematopoietic Stem/Progenitor Cells

Matilda Nifelt Hägerström, Emma Rörby, Gillian May, Ph.D., Alex Tipping, Ph.D., John Brown, Ph.D., Göran Karlsson, Ph.D., Tariq Enver, Ph.D., Stefan Karlsson, M.D., Ph.D.

Blood (2011) 118 (21): 1311.

https://doi.org/10.1182/blood.V118.21.1311.1311

Published: 2011

Journal Articles

Smad4 binds Hoxa9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by Hoxa9 and leukemia transformation

Ronan Quéré, Göran Karlsson, Falk Hertwig, Marianne Rissler, Beata Lindqvist, Thoas Fioretos, Peter Vandenberghe, Marilyn L. Slovak, Jörg Cammenga, Stefan Karlsson

Blood (2011) 117 (22): 5918–5930.

https://doi.org/10.1182/blood-2010-08-301879

Published: 2011

Includes: Supplemental data

Journal Articles

SMAD4 Sequestrates HOXA9 to Protect Hematopoietic Stem Cells Against Leukemia Transformation

Ronan Quere, PhD, Göran Karlsson, PhD, Falk Hertwig, Marianne Rissler, Beata Lindqvist, Thoas Fioretos, MD, PhD, Peter Vandenberghe, MD, PhD, Marilyn L. Slovak, PhD, Kristian Reckzeh, Jörg Cammenga, MD, PhD, Stefan Karlsson, MD, PhD

Blood (2010) 116 (21): 3153.

https://doi.org/10.1182/blood.V116.21.3153.3153

Published: 2010

Journal Articles

Studies on the Role of TGF-β1/TGF-βR1/Smad4 In the Occurance and Development of Myelocytic Leukemia and Breast Cancer

Liu Xiaoli, MD, Liping Xia, Jinfang Zhang, Qingfeng Du, Rong Li, Na Xu, Bintao Huang

Blood (2010) 116 (21): 4714.

https://doi.org/10.1182/blood.V116.21.4714.4714

Published: 2010

Journal Articles

SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression

Katarzyna Mleczko-Sanecka, Guillem Casanovas, Anan Ragab, Katja Breitkopf, Alexandra Müller, Michael Boutros, Steven Dooley, Matthias W. Hentze, Martina U. Muckenthaler

Blood (2010) 115 (13): 2657–2665.

https://doi.org/10.1182/blood-2009-09-238105

Published: 2010

Includes: Supplemental data

Journal Articles

Smif (Smad4 Interacting Factor) Is a Negative Regulator of T Cell Activation and Autoimmunity In Vivo.

Wibke Leibig, Sebastian Kuhn, Thomas Patzelt, Claudia Mugler, Bai Ren-Yuan, Leticia Quintanilla-Fend, Irmgard Förster, Christian Peschel, Jürgen Ruland, Justus Duyster

Blood (2009) 114 (22): 712.

https://doi.org/10.1182/blood.V114.22.712.712

Published: 2009

NARROW

TGF-β Signaling in Fetal Mesenchymal Progenitor Cells Plays an Essential Role in the Emergence of Bone Marrow Hematopoietic Niches

DLX1 Affects Cell Cycle and Proliferation of Myeloid Leukemia Cells In Vitro and In Vivo

An Inhibitor of TGF-β Promotes Proliferation of Normal but Not MPN Hematopoietic Cells and Is a Candidate Therapeutic Agent for the Treatment of MPN Patients Carrying JAK2 V617F or Calr pQ365fs Mutations

Dysregulation of the TGF β Pathway in Induced Pluripotent Stem Cells (iPSCs) Generated from Patients with Diamond Blackfan Anemia (DBA)

Endothelial Smad4 restrains the transition to hematopoietic progenitors via suppression of ERK activation

Epigenetic Dysregulation Of ZNF423 Impedes B-Cell Differentiation and Is Linked To Adverse Outcome Of Childhood B-Precursor ALL

Human hematopoietic stem/progenitor cells overexpressing Smad4 exhibit impaired reconstitution potential in vivo

MiR-146a Expression Level As a Molecular Marker in Acute Promyleocytic Leukemia

the miR-99∼125 P olycistrons Promote Leukemogenesis in a Cell-Context Dependent Manner by Shifting the Balance Between TGFβ- and Wnt-Signaling

Proteomic Profiling of AML Bone Marrow-Derived Mesenchymal Stem Cells (MSC) Reveals Marked Differences From Normal MSC.

Development and function of murine RORγt + iNKT cells are under TGF-β signaling control

MicroRNA-130a–mediated down-regulation of Smad4 contributes to reduced sensitivity to TGF-β1 stimulation in granulocytic precursors

Impaired Reconstitution Potential of TGFβ-Hypersensitive Human Hematopoietic Stem Cells

Mir-130a-Mediated Downregulation of SMAD4 Contributes to Reduced Sensitivity to TGFβ Stimulation in Promyelocytic Cells,

Gata2 Is a Direct Target for Smad-Mediated TGFβ Signaling in Hematopoietic Stem/Progenitor Cells

Smad4 binds Hoxa9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by Hoxa9 and leukemia transformation

SMAD4 Sequestrates HOXA9 to Protect Hematopoietic Stem Cells Against Leukemia Transformation

Studies on the Role of TGF-β1/TGF-βR1/Smad4 In the Occurance and Development of Myelocytic Leukemia and Breast Cancer

SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression

Smif (Smad4 Interacting Factor) Is a Negative Regulator of T Cell Activation and Autoimmunity In Vivo.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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