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Journal Articles

Suicide Gene Therapy with a CD33 Targeted AAV6 Vector Expressing an Inducible Caspase-9 Suicide Gene Is Therapeutic in a Xenotransplantation Model of Acute Myeloid Leukemia

Nusrat Khan, MSc, Sridhar Bammidi, Jayandharan Giridhara Rao, PhD

Blood (2019) 134 (Supplement_1): 3351.

https://doi.org/10.1182/blood-2019-125222

Published: 2019

Journal Articles

Tracking Genetically Engineered Lymphocytes Long-Term Reveals the Dynamics of T-Cell Immunological Memory

Blood (2015) 126 (23): 263.

https://doi.org/10.1182/blood.V126.23.263.263

Published: 2015

Journal Articles

Long-Term Immunological Profile of Patients Treated with Haploidentical HSCT and TK-Cells to Study the Requirements of Memory T Cell Persistence

Giacomo Oliveira, MSc, Maria Teresa Lupo Stanghellini, MD, Eliana Ruggiero, PhD, Nicoletta Cieri, MD PhD, Mattia D'Agostino, MD, Raffaella Greco, MD, Sara Mastaglio, MD, Maddalena Noviello, PhD, Luca Vago, MD PhD, Luca Biasco, PhD, Attilio Bondanza, MD PhD, Alessandro Aiuti, MD, Antonio Lambiase, MD, Manfred Schmidt, PhD, Catia Traversari, PhD, Christof von Kalle, MD, Fabio Ciceri, MD, Claudio Bordignon, MD, Chiara Bonini, MD

Blood (2014) 124 (21): 4793.

https://doi.org/10.1182/blood.V124.21.4793.4793

Published: 2014

Journal Articles

Spliceosome Mediated RNA Trans -Splicing for Targeting Kappa + B-Cell Neoplasms

Lukas Weiss, MD PhD, Christina Gruber, PhD, Ulrich Koller, PhD, Josefina Piñón-Hofbauer, PhD, Stefan Hainzl, PhD, Clemens Hufnagl, MSC, Thomas Melchardt, MD, Gabriele Brachtl, PhD, Richard Greil, MD, Johann Bauer, MD, Alexander Egle, MD

Blood (2014) 124 (21): 3633.

https://doi.org/10.1182/blood.V124.21.3633.3633

Published: 2014

Journal Articles

Long-Term Immunological Profile and T Cell Dynamics In Patients Treated With Allogeneic Transplantation and TK-Cells For Hematological Malignancies

Giacomo Oliveira, MSc, Maria Teresa Lupo Stanghellini, MD, Nicoletta Cieri, MD, Raffaella Greco, MD, Maddalena Noviello, PhD, Veronica Valtolina, BSc, Luca Vago, MD, PhD, Catia Traversari, MD, Eliana Ruggiero, PhD, Anna Paruzynski, PhD, Manfred Schmidt, PhD, Christof von Kalle, MD, PhD, Fabio Ciceri, MD, Claudio Bordignon, MD, Chiara Bonini, MD

Blood (2013) 122 (21): 165.

https://doi.org/10.1182/blood.V122.21.165.165

Published: 2013

Journal Articles

Development of gene therapy for blood disorders: an update

Arthur W. Nienhuis

Blood (2013) 122 (9): 1556–1564.

https://doi.org/10.1182/blood-2013-04-453209

Published: 2013

Journal Articles

TK-Cells Safety and Efficacy in Allogeneic Hematopoietic Stem Cell Transplantation: Long-Term Clinical and Molecular Assessment in 128 Treated Patients.

Maria Teresa Lupo-Stanghellini, MD, Giacomo Oliveira, MSc, Raffaella Greco, MD, Luca Vago, MD PhD, Attilio Bondanza, MD, PhD, Fabio Ciceri, MD, Claudio Bordignon, MD, Chiara Bonini, MD

Blood (2012) 120 (21): 3061.

https://doi.org/10.1182/blood.V120.21.3061.3061

Published: 2012

Journal Articles

Co-Expression of a Suicide Gene in CAR-Redirected T Cells Enables the Safe Targeting of CD44v6 for Leukemia and Myeloma Eradication

Monica Casucci, PhD, Benedetta Nicolis di Robilant, MSc, Laura Falcone, MSc, Barbara Camisa, BSc, Pietro Genovese, PhD, Bernhard Gentner, MD $, Luigi Naldini, MD, PhD, Barbara Savoldo, MD, PhD, Fabio Ciceri, MD, Claudio Bordignon, MD, Gianpietro Dotti, MD, Chiara Bonini, MD, Attilio Bondanza, MD, PhD

Blood (2012) 120 (21): 949.

https://doi.org/10.1182/blood.V120.21.949.949

Published: 2012

Journal Articles

T-cell suicide gene therapy prompts thymic renewal in adults after hematopoietic stem cell transplantation

Luca Vago, Giacomo Oliveira, Attilio Bondanza, Maddalena Noviello, Corrado Soldati, Domenico Ghio, Immacolata Brigida, Raffaella Greco, Maria Teresa Lupo Stanghellini, Jacopo Peccatori, Sergio Fracchia, Matteo Del Fiacco, Catia Traversari, Alessandro Aiuti, Alessandro Del Maschio, Claudio Bordignon, Fabio Ciceri, Chiara Bonini

Blood (2012) 120 (9): 1820–1830.

https://doi.org/10.1182/blood-2012-01-405670

Published: 2012

Includes: Supplemental data

Journal Articles

T Cell Suicide Gene Therapy Prompts Thymic Renewal in Adults After Haploidentical Hematopoietic Stem Cell Transplantation in the Absence of Post-Transplant Immunesuppression

Luca Vago, MD, PhD, Giacomo Oliveira, MSc, Attilio Bondanza, MD, PhD, Maddalena Noviello, MSc, Corrado Soldati, MD, Domenico Ghio, MD, Immacolata Brigida, PhD, Raffaella Greco, MD, Maria Teresa Lupo Stanghellini, MD, Jacopo Peccatori, MD, Sergio Fracchia, BSc, Matteo Del Fiacco, BSc, Catia Traversari, PhD, Alessandro Aiuti, MD, Antonio Lambiase, MD, Alessandro Del Maschio, MD, Claudio Bordignon, MD, Fabio Ciceri, MD, Chiara Bonini, MD

Blood (2011) 118 (21): 1968.

https://doi.org/10.1182/blood.V118.21.1968.1968

Published: 2011

Journal Articles

Thymic Renewal and Anti-Leukemic Effect In Adults After Haploidentical Transplantation and Donor T Cell Suicide Gene Therapy

Luca Vago, MD, PhD, Giacomo Oliveira, BSc, Maddalena Noviello, MSc, Corrado Soldati, MD, Domenico Ghio, MD, Roberto Nicoletti, MD, Immacolata Brigida, MSc, Alessandro Aiuti, MD, Maria Teresa Lupo Stanghellini, MD, Sara Mastaglio, MD, Raffaella Greco, MD, Antonio Lambiase, MD, Jacopo Peccatori, MD, Attilio Bondanza, MD, PhD, Katharina Fleischhauer, MD, Claudio Bordignon, MD, Fabio Ciceri, MD, Chiara Bonini, MD

Blood (2010) 116 (21): 833.

https://doi.org/10.1182/blood.V116.21.833.833

Published: 2010

Journal Articles

Allogeneic Suicide Gene-Modified T Cells (aSGMTC) Are Highly Cytotoxic to Non-Hematopoietic Tumor Cell Lines: Rationale for the Production of a Bank of aSGMTC for the Treatment of Solid Tumors.

Laurent Mailly, Celine Leboeuf, Christophe Ferrand, Pierre Tiberghien, Gaetan Bour, Marc Aprahamian, Michel Doffoel, Philippe Wolf, Thomas Baumert, Eric Robinet

Blood (2009) 114 (22): 2459.

https://doi.org/10.1182/blood.V114.22.2459.2459

Published: 2009

Journal Articles

Mesenchymal Stem Cells as Suicide Gene Therapy Vehicles for Organ-Confined and Metastatic Prostate Cancer (PCa).

Rosetta Martiniello-Wilks, BSc (Hons), PhD, Stephen R. Larsen, MBBS(Hons), Stephane Flamant, BSc (Hons), PhD, Jessamy C. Tiffen, BSc (Hons), Charles G. Bailey, BSc (Hons), PhD, John E.J. Rasko, BSc(Med), MBBS, PhD

Blood (2007) 110 (11): 5148.

https://doi.org/10.1182/blood.V110.11.5148.5148

Published: 2007

Journal Articles

Development of Improved Lentiviral ‘Suicide’ Gene Therapy for the Management of GvHD and GvL/GvT Responses in Allogeneic BMT.

Anton Neschadim, MSc, Takeya Sato, PhD, Daniel H. Fowler, MD, Arnon Lavie, PhD, Jeffrey A. Medin, PhD

Blood (2006) 108 (11): 3256.

https://doi.org/10.1182/blood.V108.11.3256.3256

Published: 2006

Journal Articles

Improved Suicide Gene Therapy: Lentiviral Gene Transfer of Equine Herpes Virus Type 4 Thymidine Kinase into Target Cells.

Takeya Sato, PhD, Anton Neschadim, Vanessa I. Rasaiah, Manfred Konrad, PhD, Daniel H. Fowler, MD, Arnon Lavie, PhD, Jeffrey A. Medin, PhD

Blood (2005) 106 (11): 5251.

https://doi.org/10.1182/blood.V106.11.5251.5251

Published: 2005

Journal Articles

A Novel Suicide Gene Therapy Approach for Reduction of GvHD Using Lentiviral Delivery of a Modified Human Thymidylate Monophosphate Kinase.

Takeya Sato, PhD, Anton Neschadim, Vanessa I. Rasaiah, Manfred Konrad, PhD, Daniel H. Fowler, MD, Arnon Lavie, PhD, Jeffrey A. Medin, PhD

Blood (2005) 106 (11): 5252.

https://doi.org/10.1182/blood.V106.11.5252.5252

Published: 2005

Journal Articles

Suicide Gene Therapy of Graft-Versus-Host Disease Induced by Central Memory Human T Lymphocytes.

Attilio Bondanza, MD, Veronica Valtolina, BSc, Zulma Magnani, BSc, Shin Kaneko, MD, PhD, Maurilio Ponzoni, MD, Francesca Sanvito, MD, Mark Bonyhadi, PhD, Catia Traversari, PhD, Salvatore Toma, PhD, Marina Radrizzani, BSc, Simona La Seta-Catamancio, BSc, Katharina Fleischhauer, MD, Fabio Ciceri, MD, Claudio Bordignon, MD, Chiara Bonini, MD

Blood (2005) 106 (11): 3096.

https://doi.org/10.1182/blood.V106.11.3096.3096

Published: 2005

Journal Articles

Tumor cells escape suicide gene therapy by genetic and epigenetic instability

Oliver Frank, Cornelia Rudolph, Christoph Heberlein, Nils von Neuhoff, Evelin Schröck, Axel Schambach, Brigitte Schlegelberger, Boris Fehse, Wolfram Ostertag, Carol Stocking, Christopher Baum

Blood (2004) 104 (12): 3543–3549.

https://doi.org/10.1182/blood-2004-03-0852

Published: 2004

Journal Articles

Lentiviral Delivery of Suicide Gene and Selection Molecules to Non-Dividng T Cells.

Waseem Qasim, Ilenia Chatziandreou, Adrian Thrasher, Hubert Gaspar

Blood (2004) 104 (11): 5274.

https://doi.org/10.1182/blood.V104.11.5274.5274

Published: 2004

Journal Articles

Survivin-Driven Therapy for Leukemia.

Hugo Caldas, PhD, Rachel A. Altura, MD

Blood (2004) 104 (11): 2749.

https://doi.org/10.1182/blood.V104.11.2749.2749

Published: 2004

NARROW

Suicide Gene Therapy with a CD33 Targeted AAV6 Vector Expressing an Inducible Caspase-9 Suicide Gene Is Therapeutic in a Xenotransplantation Model of Acute Myeloid Leukemia

Tracking Genetically Engineered Lymphocytes Long-Term Reveals the Dynamics of T-Cell Immunological Memory

Long-Term Immunological Profile of Patients Treated with Haploidentical HSCT and TK-Cells to Study the Requirements of Memory T Cell Persistence

Spliceosome Mediated RNA Trans -Splicing for Targeting Kappa + B-Cell Neoplasms

Long-Term Immunological Profile and T Cell Dynamics In Patients Treated With Allogeneic Transplantation and TK-Cells For Hematological Malignancies

Development of gene therapy for blood disorders: an update

TK-Cells Safety and Efficacy in Allogeneic Hematopoietic Stem Cell Transplantation: Long-Term Clinical and Molecular Assessment in 128 Treated Patients.

Co-Expression of a Suicide Gene in CAR-Redirected T Cells Enables the Safe Targeting of CD44v6 for Leukemia and Myeloma Eradication

T-cell suicide gene therapy prompts thymic renewal in adults after hematopoietic stem cell transplantation

T Cell Suicide Gene Therapy Prompts Thymic Renewal in Adults After Haploidentical Hematopoietic Stem Cell Transplantation in the Absence of Post-Transplant Immunesuppression

Thymic Renewal and Anti-Leukemic Effect In Adults After Haploidentical Transplantation and Donor T Cell Suicide Gene Therapy

Allogeneic Suicide Gene-Modified T Cells (aSGMTC) Are Highly Cytotoxic to Non-Hematopoietic Tumor Cell Lines: Rationale for the Production of a Bank of aSGMTC for the Treatment of Solid Tumors.

Mesenchymal Stem Cells as Suicide Gene Therapy Vehicles for Organ-Confined and Metastatic Prostate Cancer (PCa).

Development of Improved Lentiviral ‘Suicide’ Gene Therapy for the Management of GvHD and GvL/GvT Responses in Allogeneic BMT.

Improved Suicide Gene Therapy: Lentiviral Gene Transfer of Equine Herpes Virus Type 4 Thymidine Kinase into Target Cells.

A Novel Suicide Gene Therapy Approach for Reduction of GvHD Using Lentiviral Delivery of a Modified Human Thymidylate Monophosphate Kinase.

Suicide Gene Therapy of Graft-Versus-Host Disease Induced by Central Memory Human T Lymphocytes.

Tumor cells escape suicide gene therapy by genetic and epigenetic instability

Lentiviral Delivery of Suicide Gene and Selection Molecules to Non-Dividng T Cells.

Survivin-Driven Therapy for Leukemia.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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