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Journal Articles

Low-Dose Tamoxifen (LDTam) As a Breast Cancer (BC) Risk-Reduction Strategy in Lymphoma Survivors Exposed to Chest Radiation Therapy (RT) during Adolescence/Young Adulthood - a Randomized, Placebo-Controlled Double Blinded Phase IIb Trial

Free
Smita Bhatia, MDMPH, Melanie Palomares, MD, Lindsey Hageman, MPH, Yanjun Chen, MS, Wendy Landier, PhD CRNP, Kandice Smith, RN, Heidi Umphrey, MD, Caroline A. Reich, MD PhD, Kathryn W. Zamora, MD MPH, Saro H. Armenian, DO, MPH, Therese Bartholomew Bevers, MD, Anne Blaes, MD, Tara O. Henderson, MD MPH, David C. Hodgson, MD MPH, FRCPC, Melissa M. Hudson, MD, Larissa Korde, MD, Susan A. Melin, MD, Sofia Merajver, MD PhD, Linda Overholser, MD, Sandhya Pruthi, MD, Lennie Wong, PhD, Judy Garber, MD MPH
Journal: Blood
Blood (2019) 134 (Supplement_1): 2843.
https://doi.org/10.1182/blood-2019-126661
Published: 2019
Journal Articles

Functional Complementation between β-Catenin and Hoxa9 Sustains HSC Self-Renewal in a Prmt1-Dependent Manner

Free
Jennifer Lynch, PhD, Clemence Virely, PhD, Priscilla Lau, PhD, Huacheng Luo, PhD, Suming Huang, PhD, Eric Chi Wai So, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 449.
https://doi.org/10.1182/blood-2019-131052
Published: 2019
Journal Articles

SLC20A1 at the Interface between Macrophages and Red Blood Cells

Free
Federica Quattrone, MSc, Riem Gawish, PhD, Rui Martins, PhD, Anna-Dorothea Gorki, PhD, Martin Watzenboeck, MD, Anastasiya Hladik, Karin Lakovits, Manuele Rebsamen, PhD, Enrico Girardi, PhD, Giulio Superti-Furga, PhD, Sylvia Knapp, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 428.
https://doi.org/10.1182/blood-2019-123758
Published: 2019
Journal Articles

Autonomous Ca 2+ Oscillations Reflect Oncogenic Signaling in B-ALL Cells

Free
Kohei Kume, PhD, Liting Chen, PhD, Jaewoong Lee, PhD, Markus Müschen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1253.
https://doi.org/10.1182/blood-2019-130708
Published: 2019
Journal Articles

KLF4 Controls Leukemic Stem Cell Self-Renewal in MLL-AF9-Induced Acute Myeloid Leukemia

Free
Andrew Lewis, BS, Chun Shik Park, PhD, Monica Puppi, H. Daniel Lacorazza, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1231.
https://doi.org/10.1182/blood-2019-129164
Published: 2019
Journal Articles

Hematopoietic Hierarchy Under Steady-State and Stress Conditions

Free
Yu-Jung Tseng, BS,MS, Richard Chapple, PhD, Tianyuan Hu, PhD, Kimal Rajapakshe, Kevin Hoegenauer, BS, Cristian Coarfa, PhD, Daisuke Nakada, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1181.
https://doi.org/10.1182/blood-2019-125110
Published: 2019
Journal Articles

Smooth Muscle Cytochrome b5 Reductase 3 Deficiency Accelerates Pulmonary Hypertension Development in Sickle Cell Mice

Free
Katherine Wood, PhD BA, Brittany Durgin, PhD, Heidi M Schmidt, BSE, Scott Hahn, Jeffrey Baust, Tim Bachman, Dario A. Vitturi, PhD, Samit Ghosh, Solomon Fiifi Ofori-Acquah, Ana Mora, MD, Mark T Gladwin, MD, Adam Straub, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3619.
https://doi.org/10.1182/blood-2019-124159
Published: 2019
Journal Articles

YAP and TAZ in Fibroblastic Reticular Cells Support Hematopoiesis and Retention of Lymphocytes in Lymph Nodes

Free
Hyunsoo Cho, MD PhD, Yu Ri Kim, MD, Jieun Jang, MD, Haerim Chung, MD, Soo-Jeong Kim, Sung Yong Choi, Bae Hosung, Ralf Adams, Burkhard Ludewig, PhD, Jin Seok Kim, MD PhD, June-Won Cheong, MD PhD, Yoo Hong Min, MD PhD, Gou Young Koh
Journal: Blood
Blood (2019) 134 (Supplement_1): 3595.
https://doi.org/10.1182/blood-2019-124625
Published: 2019
Journal Articles

The Inherited MDS Gene DDX41 Is Required for Ribosome Biogenesis and Cell Viability

Free
Timothy M Chlon, PhD, Emily Stepanchick, Kwangmin Choi, PhD, Yi Zheng, PhD, Kathleen Hueneman, Ashley Davis, Daniel T. Starczynowski, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 773.
https://doi.org/10.1182/blood-2019-127471
Published: 2019
Journal Articles

Glutaminase Inhibition Overcomes Acquired Resistance to Mitochondrial Complex I in NOTCH1-Driven T-Cell Acute Lymphoblastic Leukemias (T-ALL) Via Block of Glutamine Driven Reductive Metabolism

Free
Natalia Baran, PhDMD, Alessia Lodi, PhD, Shannon Renee Sweeney, PhD, Vinitha Mary Kuruvilla, MSc, Antonio Cavazos, Daniel Herranz, PharmD, Anna Skwarska, PhD, Marc Warmoes, PhD, Eric Davis, MD, Karine Harutyunyan, PhD, Ningping Feng, PhD, Jason P Gay, MS, Marcin Kaminski, PhD, Sergej Konoplev, Elias Jabbour, MD, Adolfo A. Ferrando, MD PhD, Maria E Di Francesco, PhD, Philip Lorenzi, Joseph R Marszalek, PhD, Stefano Tiziani, PhD, Marina Y Konopleva, MD PhD, Pandey Renu, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 806.
https://doi.org/10.1182/blood-2019-128930
Published: 2019
Journal Articles

Disease Phenotype and Clonal Amplification in Calreticulin del52 and ins5 Knock-in Mice Are Dependent on the Type of Mutations and Gene Dosage

Free
Camélia Benlabiod, Maira da Costa Cacemiro, PhD, Thomas Balligand, MD, Barbara Panneau-Schmaltz, PhD, Delphine Muller, Laure Touchard, Patrick Gonin, DVM, Jean-Luc Villeval, PhD, Stefan N Constantinescu, MD PhD, Hana Raslova, PhD, William Vainchenker, MD PhD, Isabelle Plo, Caroline Marty, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 311.
https://doi.org/10.1182/blood-2019-127918
Published: 2019
Journal Articles

IL-1β Secreted from Mutant Cells Carrying JAK2- V617Ffavors Early Clonal Expansion and Promotes MPN Disease Initiation and Progression

Free
Shivam Rai, Nils Hansen, Hui Hao-Shen, Stefan Dirnhofer, Nageswara Rao Tata, Radek C. Skoda
Journal: Blood
Blood (2019) 134 (Supplement_1): 307.
https://doi.org/10.1182/blood-2019-129800
Published: 2019
Journal Articles

The VLA-4 Integrin Is Constitutively Activated in a Fraction of CD49d-Expressing Chronic Lymphocytic Leukemia Via Autonomous BCR-Mediated Signaling

Free
Erika Tissino, PhD, Tamara Bittolo, PhD, Dania Benedetti, PhD, Riccardo Bomben, PhD, Andrea Härzschel, Palash Maity, Gabriela Forestieri, Antonella Nicolò, M.Sc; B.Sc., Moumita Datta, Enrico Santinelli, MD, Francesca Maria Rossi, PhD, Alexandre Chigaev, Larry A. Sklar, Francesco Zaja, MD, Gabriele Pozzato, MD, Pietro Bulian, MD, Giovanni Francesco D'Arena, MD, Annalisa Chiarenza, MD PhD, Francesco Di Raimondo, MD, Hassan Jumaa, PhD, Davide Rossi, MD PhD, Giovanni Del Poeta, MD, Tanja Nicole Hartmann, Antonella Zucchetto, Valter Gattei, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 849.
https://doi.org/10.1182/blood-2019-124313
Published: 2019
Journal Articles

TGF-β Signaling Contributes to Myelofibrosis and Clonal Dominance of Myeloproliferative Neoplasms

Free
Juo-Chin Yao, Grazia Abou Ezzi, PhD, Joseph R. Krambs, BS, Salil Uttarwar, Eric J. Duncavage, MD, Daniel C. Link, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 470.
https://doi.org/10.1182/blood-2019-128943
Published: 2019
Journal Articles

Role of Vav1 Genomic Alterations in T-Cell Differentiation and Transformation in Peripheral T-Cell Lymphoma

Free
Jose Rodriguez Cortes, PhD, Anisha R. Cooke, Aidan Quinn, Ioan Filip, PhD, Juan Angel Patino, PhD, Raul Rabadan, PhD, Adolfo A. Ferrando, MD PhD, Teresa Palomero, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1482.
https://doi.org/10.1182/blood-2019-129438
Published: 2019
Journal Articles

Downstream Pathway of AML1-ETO Targeted ARHGEF12 Might be Targetable for Rock Inhibitor to Improve Therapy Outcome

Free
Yangyang Xie, Ruichi Wu, Xiaoxiao Chen, Xiao-Jian Sun, PhD, Shuhong Shen, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3914.
https://doi.org/10.1182/blood-2018-99-117845
Published: 2018
Journal Articles

IKZF2 Drives Self-Renewal and Blocks Myeloid Differentiation Programs in Myeloid Leukemic Stem Cells

Free
Sun-Mi Park, PhD, Hyunwoo Cho, PhD, Angela Thornton, PhD, Trevor Stephen Barlowe, BA, Timothy Chou, BS, Sagar Chhangawala, PhD, Lauren Fairchild, PhD, Arthur Chow, BA, James Taggart, BA, Alexander Schurer, BA, Antoine Gruet, Matthew Witkin, Jun Hyun Kim, Ethan Shevach, Andrei Krivstov, Scott A. Armstrong, MD PhD, Christina Leslie, PhD, Michael G. Kharas, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3881.
https://doi.org/10.1182/blood-2018-99-115034
Published: 2018
Journal Articles

Mitochondrial Complex I Inhibitor Iacs-010759 Reverses the NOTCH1-Driven Metabolic Reprogramming in T-ALL Via Blockade of Oxidative Phosphorylation: Synergy with Chemotherapy and Glutaminase Inhibition

Free
Natalia Baran, PhDMD, Alessia Lodi, PhD, Shannon Renee Sweeney, MS, Pandey Renu, PhD, Vinitha Mary Kuruvilla, Antonio Cavazos, MSc, Daniel Herranz, PharmD, Anna Skwarska, PhD, Marc Warmoes, PhD, R. Eric Davis, MD, Karine Harutyunyan, PhD, Ningping Feng, PhD, Jason P Gay, MS, Sergej Naumovich Konoplev, MD PhD, Marcin Kaminski, PhD, Jeffrey J Kovacs, PhD, Di Du, PhD, Elias J. Jabbour, MD, Adolfo A. Ferrando, MD PhD, Maria E Di Francesco, PhD, Philip L Lorenzi, PhD, Joseph R Marszalek, PhD, Stefano Tiziani, PhD, Marina Y. Konopleva, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4020.
https://doi.org/10.1182/blood-2018-99-117310
Published: 2018
Journal Articles

ESAM on the Cells of Endothelial Lineage Plays an Important Role in the Development of Definitive Hematopoiesis

Free
Tomoaki Ueda, Takafumi Yokota, MD PhD, Yoshihiro Uno, Tomoji Mashimo, Takao Sudo, Tomohiko Ishibashi, Yukiko Doi, Yasuhiro Shingai, MD, Akira Tanimura, Michiko Ichii, MD PhD, Sachiko Ezoe, MD PhD, Hirohiko Shibayama, MD PhD, Kenji Oritani, MD PhD, Yuzuru Kanakura, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3848.
https://doi.org/10.1182/blood-2018-99-111491
Published: 2018
Journal Articles

Aging of the Vascular Niche Enhances Leukemia-Initiating Cell Metabolic Switch

Free
Elisa Lazzari, PhD, Pradeep Ramalingam, MD, Michael G. Poulos, PhD, Jason M. Butler, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 871.
https://doi.org/10.1182/blood-2018-99-115019
Published: 2018