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Journal Articles

In Vitro Effects of the Novel Platelet αIIbβ3 Receptor Antagonist RUC-4 on the Verifynow Assays: Potential for Point-of-Care Monitoring of RUC-4 Therapy

Ohad S. Bentur, MD, Barry S. Coller, MD

Blood (2019) 134 (Supplement_1): 166.

https://doi.org/10.1182/blood-2019-124548

Published: 2019

Journal Articles

Acquired Platelet GPVI Dysfunction As Possible Predictor for Early Sepsis Diagnosis and Poor Outcome

Lukas J Weiss, Georgi Manukjan, PhD, Nils Nagler, Markus Kredel, MD, Thien-Tri Lam, MD, Bernhard Nieswandt, PhD, Dirk Weismann, MD, Harald Schulze, PhD

Blood (2019) 134 (Supplement_1): 3609.

https://doi.org/10.1182/blood-2019-131088

Published: 2019

Journal Articles

Dominant Role of αIIbβ3 in Platelet Interactions with Polymerizing Cross-Linked Fibrin

Claudia Lorena Buitrago, PhD, Barry S. Coller, MD, Hina Zafar

Blood (2019) 134 (Supplement_1): 1061.

https://doi.org/10.1182/blood-2019-122753

Published: 2019

Journal Articles

The Interaction of Cross-Linked Fibrin Fragment D-Dimer with αIIbβ3 Requires Receptor Activation, Occurs at Sites Other Than the γ-404-411 Sequence, and Contributes to Clot Retraction

Hina Zafar, MS, Jihong Li, MD, Claudia Buitrago, PhD, Dragana Nesic, PhD, Barry S. Coller, MD

Blood (2018) 132 (Supplement 1): 870.

https://doi.org/10.1182/blood-2018-99-116871

Published: 2018

Journal Articles

Investigating Potential Mechanism(s) By Which ASO-Based Drugs Cause Thrombocytopenia

Martina H. Lundberg Slingsby, PhD, Genevieve Couldwell, Prakrith Vijey, Brooke E Terkovich, Leila Noetzli, PhD, Ross Okazaki, Jonathan N. Thon, PhD, Scott P. Henry, PhD, Padmakumar Narayanan, DVM, PhD, Joseph E. Italiano, Jr., PhD

Blood (2018) 132 (Supplement 1): 3747.

https://doi.org/10.1182/blood-2018-99-116590

Published: 2018

Journal Articles

Thrombin-Mediated Activation of PAR-1 Contributes to Microvascular Stasis in Mouse Models of Sickle Cell Disease Via Increased Endothelial Expression of P-Selectin and VWF

Erica Sparkenbaugh, PhD BS, Chunsheng Chen, MD, Julia Nguyen, BS, Shaobin Wang, PhD, Gregory M. Vercellotti, MD, John D Belcher, PhD, Rafal Pawlinski, PhD

Blood (2018) 132 (Supplement 1): 266.

https://doi.org/10.1182/blood-2018-99-116238

Published: 2018

Journal Articles

Comparing a New Bovine Source Heparin to the Clinically Used Porcine Heparin for Platelet Function Effects and Heparin-Induced Thrombocytopenia Potential

Michelle Sung, BS, Jeanine Walenga, PhD, Walter Jeske, PhD, Omer Iqbal, MD, Mamdouh Bakhos, MD

Blood (2018) 132 (Supplement 1): 2540.

https://doi.org/10.1182/blood-2018-99-118781

Published: 2018

Journal Articles

Multiple Myeloma Treatment Is Associated with Enhanced Platelet Reactivity

Jonathan Gibbins, BSc, PhD, Rekha Rana, Dalia Khan, Susie Shapiro, MD, Henri Grech, Karthik Ramasamy, MD PhD

Blood (2018) 132 (Supplement 1): 3300.

https://doi.org/10.1182/blood-2018-99-116006

Published: 2018

Journal Articles

Pharmacokinetic (PK) and Pharmacodynamic (PD) Studies of RUC-4 Succinate, a Novel αIIbβ3 Pure Antagonist for First Point of Contact Treatment of ST Segment Elevated Myocardial Infarction (STEMI)

Spandana Vootukuri, MS, Jihong Li, MD, Mark Nedelman, MS, MBA, Mariana Babayeva, MD, PhD, Barry S. Coller, MD

Blood (2018) 132 (Supplement 1): 1243.

https://doi.org/10.1182/blood-2018-99-112233

Published: 2018

Journal Articles

The Role of Thrombin Deficiency on Skeletal Health

Hillary J Taylor, BS, Galen Goldscheitter, BS, BA, Jason A Taylor, MD PhD

Blood (2018) 132 (Supplement 1): 5012.

https://doi.org/10.1182/blood-2018-99-118989

Published: 2018

Journal Articles

Synergistic Platelet Inhibitory Effects of Riociguat and Nitric Oxide Are Decreased By Protein Binding

Yifeng WU, MD, Alan D Michelson, MD, Andrew L Frelinger, III, PhD

Blood (2018) 132 (Supplement 1): 4971.

https://doi.org/10.1182/blood-2018-99-117070

Published: 2018

Journal Articles

Platelet Integrin αIIbβ3 Activation Kinetics in Inherited Platelet Functional Disorders ∼ the Role of ADP Receptor P2Y12, Caldag-GEFI and Kindlin-3 αIIbβ3 Activation By inside-out Signaling

Hisashi Kato, MDPhD, Nobuko Nishiura, Keigo Akuta, Hirokazu Kashiwagi, Koichi Kokame, Toshiyuki Miyata, Yuzuru Kanakura, MD PhD, Yoshiaki Tomiyama, MD

Blood (2018) 132 (Supplement 1): 1136.

https://doi.org/10.1182/blood-2018-99-112852

Published: 2018

Journal Articles

Multi-Phase Ex Vivo Generation of Platelet-like Particles from CD34 + Cord Blood Cell-Derived Megakaryocytes

Jia J. Wu, BS, Darryl A. Abbott, BS, Meryem K. Terzioglu, MD, Rajeev Ranjan, PhD, Dolores Mahmud, PhD, Hasan Issa, MBBch, Neda Bagheri, PhD, Nadim Mahmud, MBBS, PhD, William M. Miller, PhD

Blood (2017) 130 (Supplement 1): 3196.

https://doi.org/10.1182/blood.V130.Suppl_1.3196.3196

Published: 2017

Journal Articles

Platelet Activation and Shear- dependent Changes in Filamin a Conformation Downstream of Ligand Binding to αIIbβ3, GPIb and α2β1 Are Reversible in Time, but Those Downstream of Fibrin Binding to αIIbβ3 Are Not

Barry S. Coller, MD, Claudia Buitrago, PhD

Blood (2017) 130 (Supplement 1): 1028.

https://doi.org/10.1182/blood.V130.Suppl_1.1028.1028

Published: 2017

Journal Articles

The Role of Platelets in the Induction of Alloimmunization after Platelet Transfusion

Anno Saris, MSc, Pieter F. Van Der Meer, PhD, Sander Meijer, PhD, Ivan Peyron, Marieke van Ham, PhD, Anja ten Brinke, PhD, Jaap Jan Zwaginga, MD PhD

Blood (2017) 130 (Supplement 1): 3726.

https://doi.org/10.1182/blood.V130.Suppl_1.3726.3726

Published: 2017

Journal Articles

Brain-Derived Neurotrophic Factor Induces Platelet Aggregation

Rahma Boulahya, PhD, Audrey Béliveau, BSc, Asmaa Harim, Fabio Luiz Bandeira Ferreira, BPharm, MSc, Jean-François Tanguay, MD, Yahye Merhi, PhD, Marie Lordkipanidzé, BPharm, PhD

Blood (2017) 130 (Supplement 1): 3612.

https://doi.org/10.1182/blood.V130.Suppl_1.3612.3612

Published: 2017

Journal Articles

Mitochondrial Fission Protein Drp1 Regulates Megakaryocyte and Platelet Mitochondrial Morphology, Platelet Numbers, and Platelet Function

Emilia A Tugolukova, Robert A. Campbell, PhD, Kelly B Hoerger, Hansjorg Schwertz, MD, Andrew S. Weyrich, PhD, Jesse W Rowley, PhD

Blood (2017) 130 (Supplement 1): 455.

https://doi.org/10.1182/blood.V130.Suppl_1.455.455

Published: 2017

Journal Articles

Mass Cytometry of Platelets: Simultaneous Functional and Phenotypic Analysis of Multiple Surface Markers in Healthy Subjects and Patients with Inherited Platelet Disorders Reveals Novel Platelet Sub-Populations

Thomas A. Blair, PhD, Alan D Michelson, MD, Andrew L Frelinger, III, PhD

Blood (2017) 130 (Supplement 1): 2311.

https://doi.org/10.1182/blood.V130.Suppl_1.2311.2311

Published: 2017

Journal Articles

Platelet Function in Thrombocytopenic Patients with Chronic Liver Disease

Elena Smolensky Koganov, PhD, Sabrina L Carmichael, BS, Emma E Forde, BS, Andrew L Frelinger, III, PhD, Alan D Michelson, MD

Blood (2017) 130 (Supplement 1): 2314.

https://doi.org/10.1182/blood.V130.Suppl_1.2314.2314

Published: 2017

Journal Articles

A Portable System for Processing Donated Whole Blood into High Quality Components without Centrifugation

Sean C. Gifford, PhD, Briony C. Strachan, PhD, Hui Xia, PhD, Eszter Vörös, PhD, Kian Torabian, BS, Taylor A. Tomasino, BS, Gary D. Griffin, MS, Benjamin Lichtiger, MD PhD, Fleur M. Aung, MD, Sergey S. Shevkoplyas, PhD

Blood (2017) 130 (Supplement 1): 2401.

https://doi.org/10.1182/blood.V130.Suppl_1.2401.2401

Published: 2017

NARROW

In Vitro Effects of the Novel Platelet αIIbβ3 Receptor Antagonist RUC-4 on the Verifynow Assays: Potential for Point-of-Care Monitoring of RUC-4 Therapy

Acquired Platelet GPVI Dysfunction As Possible Predictor for Early Sepsis Diagnosis and Poor Outcome

Dominant Role of αIIbβ3 in Platelet Interactions with Polymerizing Cross-Linked Fibrin

The Interaction of Cross-Linked Fibrin Fragment D-Dimer with αIIbβ3 Requires Receptor Activation, Occurs at Sites Other Than the γ-404-411 Sequence, and Contributes to Clot Retraction

Investigating Potential Mechanism(s) By Which ASO-Based Drugs Cause Thrombocytopenia

Thrombin-Mediated Activation of PAR-1 Contributes to Microvascular Stasis in Mouse Models of Sickle Cell Disease Via Increased Endothelial Expression of P-Selectin and VWF

Comparing a New Bovine Source Heparin to the Clinically Used Porcine Heparin for Platelet Function Effects and Heparin-Induced Thrombocytopenia Potential

Multiple Myeloma Treatment Is Associated with Enhanced Platelet Reactivity

Pharmacokinetic (PK) and Pharmacodynamic (PD) Studies of RUC-4 Succinate, a Novel αIIbβ3 Pure Antagonist for First Point of Contact Treatment of ST Segment Elevated Myocardial Infarction (STEMI)

The Role of Thrombin Deficiency on Skeletal Health

Synergistic Platelet Inhibitory Effects of Riociguat and Nitric Oxide Are Decreased By Protein Binding

Platelet Integrin αIIbβ3 Activation Kinetics in Inherited Platelet Functional Disorders ∼ the Role of ADP Receptor P2Y12, Caldag-GEFI and Kindlin-3 αIIbβ3 Activation By inside-out Signaling

Multi-Phase Ex Vivo Generation of Platelet-like Particles from CD34 + Cord Blood Cell-Derived Megakaryocytes

Platelet Activation and Shear- dependent Changes in Filamin a Conformation Downstream of Ligand Binding to αIIbβ3, GPIb and α2β1 Are Reversible in Time, but Those Downstream of Fibrin Binding to αIIbβ3 Are Not

The Role of Platelets in the Induction of Alloimmunization after Platelet Transfusion

Brain-Derived Neurotrophic Factor Induces Platelet Aggregation

Mitochondrial Fission Protein Drp1 Regulates Megakaryocyte and Platelet Mitochondrial Morphology, Platelet Numbers, and Platelet Function

Mass Cytometry of Platelets: Simultaneous Functional and Phenotypic Analysis of Multiple Surface Markers in Healthy Subjects and Patients with Inherited Platelet Disorders Reveals Novel Platelet Sub-Populations

Platelet Function in Thrombocytopenic Patients with Chronic Liver Disease

A Portable System for Processing Donated Whole Blood into High Quality Components without Centrifugation

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American Society of Hematology

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ASH Publications

American Society of Hematology

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