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Journal Articles

The Critical Role of Kindlin-3 in Intiation of Physiological Thrombus Formation ~ Analysis of Kindlin-3 Deficient Patient

Hisashi Kato, MD PhD, Shigenori Honda, MD, Hirokazu Kashiwagi, Nobuko Nishiura, Keigo Akuta, Koichi Kokame, Toshiyuki Miyata, Yoshiaki Tomiyama, MD

Blood (2019) 134 (Supplement_1): 1062.

https://doi.org/10.1182/blood-2019-129668

Published: 2019

Journal Articles

αIIb(R990W), a Gain-of Function Mutation of αIIbβ3, Knock-in Mice Show Moderately Impaired Thrombopoiesis

Keigo Akuta, Kazunobu Kiyomizu, MD, Hirokazu Kashiwagi, Shinji Kunishima, PhD, Fumiaki Banno, Koichi Kokame, Nobuko Nishiura, Hisashi Kato, MD PhD, Shigenori Honda, MD, Yuzuru Kanakura, MD PhD, Toshiyuki Miyata, Yoshiaki Tomiyama, MD

Blood (2018) 132 (Supplement 1): 3743.

https://doi.org/10.1182/blood-2018-99-115953

Published: 2018

Journal Articles

Platelet Integrin αIIbβ3 Activation Kinetics in Inherited Platelet Functional Disorders ∼ the Role of ADP Receptor P2Y12, Caldag-GEFI and Kindlin-3 αIIbβ3 Activation By inside-out Signaling

Hisashi Kato, MDPhD, Nobuko Nishiura, Keigo Akuta, Hirokazu Kashiwagi, Koichi Kokame, Toshiyuki Miyata, Yuzuru Kanakura, MD PhD, Yoshiaki Tomiyama, MD

Blood (2018) 132 (Supplement 1): 1136.

https://doi.org/10.1182/blood-2018-99-112852

Published: 2018

Journal Articles

Exacerbated venous thromboembolism in mice carrying a protein S K196E mutation

Fumiaki Banno, Toshiyuki Kita, José A. Fernández, Hiroji Yanamoto, Yuko Tashima, Koichi Kokame, John H. Griffin, Toshiyuki Miyata

Blood (2015) 126 (19): 2247–2253.

https://doi.org/10.1182/blood-2015-06-653162

Published: 2015

Includes: Supplemental data

Journal Articles

αIIb(R990W), a Constitutive Activating Mutation of Integrin αIIbβ3, Knock-in Mice Show Macrothrombocytopenia with Impairment of Platelet Function

Kazunobu Kiyomizu, Hirokazu Kashiwagi, Shinji Kunishima, PhD, Fumiaki Banno, PhD, Hisashi Kato, Youichiro Morikawa, Seiji Tadokoro, Koichi Kokame, PhD, Shigenori Honda, MD PhD, Toshiyuki Miyata, PhD, Yuzuru Kanakura, Yoshiaki Tomiyama

Blood (2014) 124 (21): 4182.

https://doi.org/10.1182/blood.V124.21.4182.4182

Published: 2014

Journal Articles

A Long-Term Phenotype Analysis Of 51 Patients With Upshaw–Schulman Syndrome In Japan, With Special References To Pregnancy and Renal Failure That Requires Hemodialysis

Yoshihiro Fujimura, MD, PhD, Yumi Yoshii, MD, Masanori Matsumoto, MD, PhD, Ayami Isonishi, BS, Masaki Hayakawa, MD, Yoko Yoshida, MS, Hideo Yagi, MD, PhD, Koichi Kokame, PhD, Toshiyuki Miyata, PhD

Blood (2013) 122 (21): 3545.

https://doi.org/10.1182/blood.V122.21.3545.3545

Published: 2013

Journal Articles

ADAMTS13 Improving the Cell Engraftment Efficacy in Mouse Model of Bone Marrow Transplantation

Hideto Matsui, MD, Masaaki Doi, MD, Yasunori Matsunari, MD, Maiko Takeda, MD, Kenji Nishio, MD, Midori Shima, MD, Kenji Soejima, PhD, Fumiaki Banno, PhD, Masashi Akiyama, PhD, Koichi Kokame, PhD, Toshiyuki Miyata, PhD, Mitsuhiko Sugimoto, MD

Blood (2012) 120 (21): 1077.

https://doi.org/10.1182/blood.V120.21.1077.1077

Published: 2012

Journal Articles

Protective Role of ADAMTS13 for Myocardium in Mouse Model of Experimental Myocardial Infarction.

Masaaki Doi, MD, Hideto Matsui, MD, Yukiji Takeda, MD, Yoshihiko Saito, MD, Maiko Takeda, MD, Yasunori Matsunari, MD, Kenji Nishio, MD, Midori Shima, MD, Fumiaki Banno, PhD, Masashi Akiyama, PhD, Koichi Kokame, PhD, Toshiyuki Miyata, PhD, Mitsuhiko Sugimoto, MD

Blood (2012) 120 (21): 2175.

https://doi.org/10.1182/blood.V120.21.2175.2175

Published: 2012

Journal Articles

Satb1 Determines Hematopoietic Stem Cell Differentiation Toward the Lymphoid Lineages

Yusuke Satoh, MD, PhD, Takafumi Yokota, MD, PhD, Motonari Kondo, MD, PhD, Paul W. Kincade, PhD, Taku Kouro, PhD, Ryuji Iida, PhD, Koichi Kokame, PhD, Toshiyuki Miyata, PhD, Takao Sudo, MD, Hirokazu Tanaka, MD, PhD, Itaru Matsumura, MD, PhD, Kenji Oritani, MD, PhD, Terumi Kohwi-Shigematsu, PhD, Yuzuru Kanakura, MD, PhD

Blood (2011) 118 (21): 388.

https://doi.org/10.1182/blood.V118.21.388.388

Published: 2011

Journal Articles

A Chromatin Modifier SATB1 Promotes Lymphocyte Production From Primitive Hematopoietic Stem/Progenitor Cells

Yusuke Satoh, MD, PhD, Takafumi Yokota, MD, PhD, Hirokazu Tanaka, MD, PhD, Koichi Kokame, PhD, Toshiyuki Miyata, PhD, Itaru Matsumura, MD, PhD, Kenji Oritani, MD, PhD, Yuzuru Kanakura, MD, PhD

Blood (2010) 116 (21): 836.

https://doi.org/10.1182/blood.V116.21.836.836

Published: 2010

Journal Articles

ADAMTS13 gene deletion aggravates ischemic brain damage: a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion

Masayuki Fujioka, Kazuhide Hayakawa, Kenichi Mishima, Ai Kunizawa, Keiichi Irie, Sei Higuchi, Takafumi Nakano, Carl Muroi, Hidetada Fukushima, Mitsuhiko Sugimoto, Fumiaki Banno, Koichi Kokame, Toshiyuki Miyata, Michihiro Fujiwara, Kazuo Okuchi, Kenji Nishio

Blood (2010) 115 (8): 1650–1653.

https://doi.org/10.1182/blood-2009-06-230110

Published: 2010

Journal Articles

The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation

Fumiaki Banno, Anil K. Chauhan, Koichi Kokame, Jin Yang, Shigeki Miyata, Denisa D. Wagner, Toshiyuki Miyata

Blood (2009) 113 (21): 5323–5329.

https://doi.org/10.1182/blood-2008-07-169359

Published: 2009

Journal Articles

The endothelial antigen ESAM marks primitive hematopoietic progenitors throughout life in mice

Takafumi Yokota, Kenji Oritani, Stefan Butz, Koichi Kokame, Paul W. Kincade, Toshiyuki Miyata, Dietmar Vestweber, Yuzuru Kanakura

Blood (2009) 113 (13): 2914–2923.

https://doi.org/10.1182/blood-2008-07-167106

Published: 2009

Includes: Supplemental data

Journal Articles

ADAMTS13 Gene Deletion Aggravates Ischemic Brain Damage

Kenji Nishio, Masayuki Fujioka, Kazuhide Hayakawa, Kenichi Mishima, Michihiro Fujiwara, Fumiaki Banno, Koichi Kokame, Toshiyuki Miyata, Yasuaki Shida, Mitsuhiko Sugimoto, Hidetada Fukushima, Kazuo Okuchi

Blood (2008) 112 (11): 260.

https://doi.org/10.1182/blood.V112.11.260.260

Published: 2008

Journal Articles

The Endothelial Antigen ESAM Marks Hematopoietic Stem Cells throughout Life

Takafumi Yokota, Kenji Oritani, Stefan Butz, Koichi Kokame, Paul W Kincade, Toshiyuki Miyata, Dietmar Vestweber, Yuzuru Kanakura

Blood (2008) 112 (11): 727.

https://doi.org/10.1182/blood.V112.11.727.727

Published: 2008

Journal Articles

Natural History of 33 Patients with Upshaw-Schulman Syndrome Has Revealed That All the Gravida Develop Thrombocytopenia, Often Followed by Thrombotic Microangiopathy with Stillbirth.

Blood (2007) 110 (11): 3211.

https://doi.org/10.1182/blood.V110.11.3211.3211

Published: 2007

Journal Articles

Upshaw-Schulman Syndrome Revealed by Pregnancy.

Masako Seike, MD, Teruhiko Kozuka, MD, Koichi Kokame, MD, Toshiyuki Miyata, MD, Tomomi Matsuyama, MD, Masanori Matsumoto, MD, Yoshihiro Fujimura, MD, Masamichi Hara, MD

Blood (2006) 108 (11): 3951.

https://doi.org/10.1182/blood.V108.11.3951.3951

Published: 2006

Journal Articles

Complete deficiency in ADAMTS13 is prothrombotic, but it alone is not sufficient to cause thrombotic thrombocytopenic purpura

Fumiaki Banno, Koichi Kokame, Tomohiko Okuda, Shigenori Honda, Shigeki Miyata, Hisashi Kato, Yoshiaki Tomiyama, Toshiyuki Miyata

Blood (2006) 107 (8): 3161–3166.

https://doi.org/10.1182/blood-2005-07-2765

Published: 2006

Journal Articles

Upshaw-Schulman Syndrome: A Masqueraded Thrombocytopenia during Pregnancy.

Tomomi Matsuyama, Masanori Matsumoto, Seiji Kato, Nobu Akiyama, Junji Tomiyama, Kazuhiko Natori, Yasunobu Kuraishi, Yutaka Imamura, Nobumasa Inoue, Koichi Kokame, Toshiyuki Miyata, Yoshihiro Fujimura

Blood (2005) 106 (11): 2644.

https://doi.org/10.1182/blood.V106.11.2644.2644

Published: 2005

Journal Articles

Molecular characterization of ADAMTS13 gene mutations in Japanese patients with Upshaw-Schulman syndrome

Masanori Matsumoto, Koichi Kokame, Kenji Soejima, Masayoshi Miura, Syuhei Hayashi, Yasuhiko Fujii, Asayuki Iwai, Etsuro Ito, Yoichiro Tsuji, Mayuko Takeda-Shitaka, Mitsuo Iwadate, Hideaki Umeyama, Hideo Yagi, Hiromichi Ishizashi, Fumiaki Banno, Tomohiro Nakagaki, Toshiyuki Miyata, Yoshihiro Fujimura

Blood (2004) 103 (4): 1305–1310.

https://doi.org/10.1182/blood-2003-06-1796

Published: 2004

NARROW

The Critical Role of Kindlin-3 in Intiation of Physiological Thrombus Formation ~ Analysis of Kindlin-3 Deficient Patient

αIIb(R990W), a Gain-of Function Mutation of αIIbβ3, Knock-in Mice Show Moderately Impaired Thrombopoiesis

Platelet Integrin αIIbβ3 Activation Kinetics in Inherited Platelet Functional Disorders ∼ the Role of ADP Receptor P2Y12, Caldag-GEFI and Kindlin-3 αIIbβ3 Activation By inside-out Signaling

Exacerbated venous thromboembolism in mice carrying a protein S K196E mutation

αIIb(R990W), a Constitutive Activating Mutation of Integrin αIIbβ3, Knock-in Mice Show Macrothrombocytopenia with Impairment of Platelet Function

A Long-Term Phenotype Analysis Of 51 Patients With Upshaw–Schulman Syndrome In Japan, With Special References To Pregnancy and Renal Failure That Requires Hemodialysis

ADAMTS13 Improving the Cell Engraftment Efficacy in Mouse Model of Bone Marrow Transplantation

Protective Role of ADAMTS13 for Myocardium in Mouse Model of Experimental Myocardial Infarction.

Satb1 Determines Hematopoietic Stem Cell Differentiation Toward the Lymphoid Lineages

A Chromatin Modifier SATB1 Promotes Lymphocyte Production From Primitive Hematopoietic Stem/Progenitor Cells

ADAMTS13 gene deletion aggravates ischemic brain damage: a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion

The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation

The endothelial antigen ESAM marks primitive hematopoietic progenitors throughout life in mice

ADAMTS13 Gene Deletion Aggravates Ischemic Brain Damage

The Endothelial Antigen ESAM Marks Hematopoietic Stem Cells throughout Life

Natural History of 33 Patients with Upshaw-Schulman Syndrome Has Revealed That All the Gravida Develop Thrombocytopenia, Often Followed by Thrombotic Microangiopathy with Stillbirth.

Upshaw-Schulman Syndrome Revealed by Pregnancy.

Complete deficiency in ADAMTS13 is prothrombotic, but it alone is not sufficient to cause thrombotic thrombocytopenic purpura

Upshaw-Schulman Syndrome: A Masqueraded Thrombocytopenia during Pregnancy.

Molecular characterization of ADAMTS13 gene mutations in Japanese patients with Upshaw-Schulman syndrome

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American Society of Hematology

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