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Journal Articles

Novel drivers and modifiers of MPL-dependent oncogenic transformation identified by deep mutational scanning

Brief Report
Jessica L. Bridgford, Su Min Lee, Christine M. M. Lee, Paola Guglielmelli, Elisa Rumi, Daniela Pietra, Stephen Wilcox, Yash Chhabra, Alan F. Rubin, Mario Cazzola, Alessandro M. Vannucchi, Andrew J. Brooks, Matthew E. Call, Melissa J. Call
Journal: Blood
Blood (2020) 135 (4): 287–292.
https://doi.org/10.1182/blood.2019002561
Published: 2020
Includes: Supplemental data
Journal Articles

Human PAR4 Is a More Potent Receptor for Activating Platelets Than Mouse PAR4

Stephanie Renna, Leonard C. Edelstein, PhD, Steven Edward McKenzie, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4883.
https://doi.org/10.1182/blood-2019-128250
Published: 2019
Journal Articles

MDSC Suppression of CAR T Cells Can be Reduced By Targeted Signaling Disruption

Estelle V Cervantes, Justin C. Boucher, PhD, Sae Bom Lee, Kristen Spitler, Kayla Reid, Marco L. Davila, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4438.
https://doi.org/10.1182/blood-2019-122752
Published: 2019
Journal Articles

Human Pluripotent Stem Cell-Derived Blood Cells for Therapies

Dan S Kaufman, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): SCI-14.
https://doi.org/10.1182/blood-2018-99-109424
Published: 2018
Journal Articles

Unique Transmembrane Domain Interactions Differentially Modulate Platelet αIIbβ3 and αvβ3 Function

Rustem I. Litvinov, MD PhD, Marco Mravic, B.S., M.S., Hua Zhu, BS, John W. Weisel, PhD, William F. DeGrado, PhD, Joel S. Bennett, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1019.
https://doi.org/10.1182/blood.V130.Suppl_1.1019.1019
Published: 2017
Journal Articles

Interaction of Both SH2 Domains of SHP-2 with a PD-1 Homodimer Is Required for PD-1-Mediated Inhibition of T Cell Responses

Nikolaos Patsoukis, PhD, Asia Council, Anders Berg, MD PhD, Kankana Bardhan, PhD, Jessica D Weaver, PhD, Kathleen M. Mahoney, MD PhD, Gordon J. Freeman, PhD, Vassiliki A. Boussiotis, MD PhD
Journal: Blood
Blood (2016) 128 (22): 859.
https://doi.org/10.1182/blood.V128.22.859.859
Published: 2016
Journal Articles

Development of Novel Non-Immunoglobulin Centyrin-Based Cars (CARTyrins) Targeting Human Bcma

Burton Earle Barnett, PhD, Xinxin Wang, PhD, David L. Hermanson, PhD, Yening Tan, B.S., Eric M. Osertag, MD PhD, Devon J. Shedlock, PhD
Journal: Blood
Blood (2016) 128 (22): 4557.
https://doi.org/10.1182/blood.V128.22.4557.4557
Published: 2016
Journal Articles

Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative

Katherine Tarlock, MD, M. Eva Hansen, Tiffany Hylkema, Rhonda Ries, MA, Jason E. Farrar, MD, Jaime Guidry Auvil, Daniela S. Gerhard, PhD, Malcolm A. Smith, MD PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, Leandro C. Hermida, Marco A Marra, PhD, Andrew J. Mungall, PhD, Karen Mungall, PhD, Yussanne Ma, Stuart Zong, William Long, PhD, Titus Boggon, PhD, Todd A. Alonzo, PhD, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 87.
https://doi.org/10.1182/blood.V126.23.87.87
Published: 2015
Journal Articles

Elongation of MPL Transmembrane Domain Is a Novel Activating-Mutation in Essential Thrombocythemia

Yukiya Yamamoto, MD PhD, Sachiko Iba, Akihiro Abe, MD PhD, Nobuhiko Emi, MDPhD
Journal: Blood
Blood (2015) 126 (23): 1628.
https://doi.org/10.1182/blood.V126.23.1628.1628
Published: 2015
Journal Articles

Silencing Mutations in NOTCH1 Activate Calcium Signaling in B Cells

Cassandra L Love, MS, Jane Healy, MD PhD, Adrienne Greenough, PhD, Sandeep S. Dave, MD, Guojie Li
Journal: Blood
Blood (2014) 124 (21): 1696.
https://doi.org/10.1182/blood.V124.21.1696.1696
Published: 2014
Journal Articles

Pre-Clinical Development Of a Novel Chimerical Antigen Receptor Targeting High-Risk Pediatric ALL Over-Expressing Tslpr

Haying Qin, Cho Monica, Waleed Haso, M.S., Ling Zhang, David M. Barrett, MD/PhD, Rimas J Orentas, PhD, Stephan A. Grupp, MD, PhD, Terry J Fry, MD
Journal: Blood
Blood (2013) 122 (21): 2665.
https://doi.org/10.1182/blood.V122.21.2665.2665
Published: 2013
Journal Articles

Combining Oncolytic Vaccinia Virotherapy with Adoptive T Cell Therapy,

Minhtran Charlotte Ngo, Jun Ando, MD, PhD, Ann M. Leen, PhD, Caroline Breitbach, PhD, Anne Moon, David Kirn, MD, John Bell, PhD, Cliona M. Rooney, PhD
Journal: Blood
Blood (2011) 118 (21): 4042.
https://doi.org/10.1182/blood.V118.21.4042.4042
Published: 2011
Journal Articles

Assessing the Biochemistry of Kindlin-3 In Human Platelets

Craig N. Streu, Ph.D., David Thomas Moore, B.S., M.S., Paul C. Billings, Ph.D., Patrik Nygren, Ph.D., Karen P. Fong, Ph.D., Douglas G. Metcalf, Ph.D., Yibing Wu, Ph.D., William F. DeGrado, Ph.D., Joel S. Bennett, MD
Journal: Blood
Blood (2010) 116 (21): 2011.
https://doi.org/10.1182/blood.V116.21.2011.2011
Published: 2010
Journal Articles

Significant functional heterogeneity among KIR2DL1 alleles and a pivotal role of arginine 245

Rafijul Bari, Teresa Bell, Wai-Hang Leung, Queenie P. Vong, Wing Keung Chan, Neha Das Gupta, Martha Holladay, Barbara Rooney, Wing Leung
Journal: Blood
Blood (2009) 114 (25): 5182–5190.
https://doi.org/10.1182/blood-2009-07-231977
Published: 2009
Includes: Supplemental data
Journal Articles

Identification of Stalk Mutations That Stabilize the High Affinity Conformation of αIIbβ3 by Negative Design.

Jason E. Donald, PhD, Hua Zhu, BS, William F. DeGrado, PhD, Joel S. Bennett, MD
Journal: Blood
Blood (2009) 114 (22): 4017.
https://doi.org/10.1182/blood.V114.22.4017.4017
Published: 2009
Journal Articles

Molecular Control of Mitochondrial Apoptosis by the BCL-2 Family.

Emily Cheng, MD, PhD
Journal: Blood
Blood (2009) 114 (22): SCI-13.
https://doi.org/10.1182/blood.V114.22.SCI-13.SCI-13
Published: 2009
Journal Articles

A Conserved Transmembrane Domain Interface Regulates Integrin Function

Bryan W Berger, Lisa M. Span, Daniel W Kulp, Paul C. Billings, William F. DeGrado, Joel S. Bennett, MD
Journal: Blood
Blood (2008) 112 (11): 2858.
https://doi.org/10.1182/blood.V112.11.2858.2858
Published: 2008
Journal Articles

Ectopic Expression of the Extracellular Domain of Mpl Is Sufficient to Induce a Hematopoietic Population Crisis

Daniel C. Wicke, Johann Meyer, Guntram Büsche, MD, Hans Kreipe, MD, Zhixiong Li, MD, Karl Welte, Matthias Ballmaier, Christopher Baum, Ute Modlich
Journal: Blood
Blood (2008) 112 (11): 2886.
https://doi.org/10.1182/blood.V112.11.2886.2886
Published: 2008
Journal Articles

The Transmembrane Domain of PDGFR-β Plays An Important Role in ETV6-PDGFR-β Activation

Federica Toffalini, MSc, Jean-Baptiste Demoulin, PhD
Journal: Blood
Blood (2008) 112 (11): 5320.
https://doi.org/10.1182/blood.V112.11.5320.5320
Published: 2008
Journal Articles

AKR-501 Activates the Thrombopoietin Receptor through Interaction with the Transmembrane Domain

Jie Zhang, Jesse Alt, Min Yang, Akhil Baranwal, MD, Thomas M. Luby
Journal: Blood
Blood (2008) 112 (11): 5391.
https://doi.org/10.1182/blood.V112.11.5391.5391
Published: 2008