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Journal Articles

Zebrafish Xenotransplantation and Focused Chemical Genomics: A Preclinical Therapeutic Model For T-Cell Acute Lymphoblastic Leukemia

Victoria L Bentley, BSc, Chansey J Veinotte, MSc, Dale Corkery, BSc., Marissa A Leblanc, PhD, Karen Bedard, PhD, Andrew P Weng, MD, PhD, Graham Dellaire, PhD., Jason N Berman, MD

Blood (2013) 122 (21): 2670.

https://doi.org/10.1182/blood.V122.21.2670.2670

Published: 2013

Journal Articles

IGFBP7 Gene Promoting Cell Proliferation in Acute Myeloid Leukemia Through Activation of AKT3 and CCND1

Shaoyan Hu, MD, PhD, Shui-yan Wu, MD, Jian-nong Cen, MD, Jian Pan, Ph.D., Xiaofei Qi, Ph.D., Zixing Chen, MD, Ph.D., Xing Feng, MD, Ph.D., Chien-Shing Chen, MD, PhD

Blood (2012) 120 (21): 1447.

https://doi.org/10.1182/blood.V120.21.1447.1447

Published: 2012

Journal Articles

Novel Recurrent Mutations in the Ras -Like GTP-Binding Gene Rit1 in Myeloid Malignancies

Inées Góomez-Seguíi, MD., Hideki Makishima, MD, PhD, Andres Jerez, MD, PhD, Kenichi Yoshida, MD, Bartlomiej P Przychodzen, Satoru Miyano, PhD, Yuichi Shiraishi, Holleh D Husseinzadeh, MD, Edward P Evans, Kathryn M Guinta, Naoko Hosono, MD., PhD., Michael A McDevitt, MD, PhD, Alison R. Moliterno, MD, Mikkael A. Sekeres, MD, MS, Seishi Ogawa, MD, PhD, Jaroslaw P. Maciejewski, MD, PhD

Blood (2012) 120 (21): 558.

https://doi.org/10.1182/blood.V120.21.558.558

Published: 2012

Journal Articles

Inhibition of AKT Signaling Potently Inhibits the Growth of JAK and MPL-Mutant Cells in the Myeloproliferative Neoplasms In Vitro and In Vivo,

Irum Khan, MBBS, Zan Huang, PhD, Qiang Jeremy Wen, MD, PhD, Priya Koppikar, Ross L Levine, MD, Ayalew Tefferi, MD, John Crispino, PhD

Blood (2011) 118 (21): 3862.

https://doi.org/10.1182/blood.V118.21.3862.3862

Published: 2011

Journal Articles

Effect of a Novel Nucleoside Analogue, Triciribine Phosphate (TCN-P) on Murine Acute Graft-Vrs-Host Disease (aGvHD)

Edward Dela Ziga, MD, MPH, Jaebok Choi, PhD., Mark Needles, Julie Ritchey, John F. DiPersio, MD, PhD

Blood (2011) 118 (21): 2977.

https://doi.org/10.1182/blood.V118.21.2977.2977

Published: 2011

Journal Articles

Inhibition of AKT Signaling Potently Inhibits Growth of MPL-Mutant Cells in the Myeloproliferative Neoplasms.

Zan Huang, PhD, Priya Koppikar, PhD, Thomas Mercher, Ph.D, Ross L. Levine, MD, John Crispino, PhD

Blood (2009) 114 (22): 1896.

https://doi.org/10.1182/blood.V114.22.1896.1896

Published: 2009

Journal Articles

The Role of the PI3K-AKT-mTOR Pathway in NK Cell Anti-Tumor Reactivity.

Matthias Krusch, MD, Julia Salih, Ingrid Kumbier, Carolin Fenner, Lothar Kanz, MD, Helmut R Salih, MD

Blood (2009) 114 (22): 3690.

https://doi.org/10.1182/blood.V114.22.3690.3690

Published: 2009

Journal Articles

Phase I Study of the Akt-Inhibitor Triciribine Phosphate Monohydrate in Patients with Advanced Hematologic Malignancy

Farhad Ravandi, MBBS, Deepa Sampath, PhD, William Plunkett, PhD, Betsy Williams, RN, Michelle Burton, RN, Srdan Verstovsek, Stefan Faderl, MD, Guillermo Garcia-Manero, MD, Vernon Alvarez, PhD, Michael D Becker, Alan F. List, MD, Said Sebti, PhD, Hagop M. Kantarjian, MD, Jeffrey Lancet, MD

Blood (2008) 112 (11): 2987.

https://doi.org/10.1182/blood.V112.11.2987.2987

Published: 2008

Journal Articles

Rho-a and Rac-1 GTPases Play Major and Differential Roles in SDF1α- Induced Cell Adhesion and Chemotaxis in Multiple Myeloma.

Abdel kareem Azab, Feda Azab, Costas M Pitsillides, Hai T. Ngo, Xiaoying Jia, Molly R. Melhem, Judith Runnels, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Nicholas Burwick, Charles P Lin, Kenneth C Anderson, MD, Irene M. Ghobrial

Blood (2008) 112 (11): 1666.

https://doi.org/10.1182/blood.V112.11.1666.1666

Published: 2008

Journal Articles

BCL2 Induces Suppressor of Cytokine Signaling-3 (SOCS3) Expression in Murine B Cells Via Pathways Involving an HSP70/90 Complex and Activation of p44/42 Map Kinase.

Aric Parnes, MD, Julie Kim, M.D., Ph.D., Sofya Rodov, K. Gary J. Vanasse, M.D.

Blood (2007) 110 (11): 2199.

https://doi.org/10.1182/blood.V110.11.2199.2199

Published: 2007

Journal Articles

Phase I Study of Triciribine Phosphate Monohydrate, a Specific Inhibitor of AKt Phosphorylation, in Adult Patients with Advanced Hematologic Malignancies.

Farhad Ravandi, MD, Jeffrey Lancet, MD, Francis Giles, MD, William Plunkett, PhD, Betsy Williams, RN, Michelle Burton, RN, Stefan Faderl, MD, Zeev Estrov, MD, Gautam Borthakur, MD, Lawrence Akinsanmi, MD, Hagop Kantarjian, MD

Blood (2007) 110 (11): 913.

https://doi.org/10.1182/blood.V110.11.913.913

Published: 2007

Journal Articles

Functional and Molecular Analysis of Oncogenic Pathways in Primary Myeloma Cells.

Angela Zöllinger, Thorsten Stühmer, Michael Sachs, Christian Keicher, Hermann Einsele, Ralf C. Bargou

Blood (2006) 108 (11): 5016.

https://doi.org/10.1182/blood.V108.11.5016.5016

Published: 2006

Journal Articles

Molecular Mechanisms Regulating Resistance to the Akt Inhibitor Perifosine in Waldenstrom’s Macroglobulinemia, the Role of the ERK and PKC Pathways.

Xavier Leleu, MD, Hai Ngo, Xiaoying Jia, Anne-Sophie Moreau, MD, Evdoxia Hatjiharisi, MD, Ruben Carrasco, MD, Garrett O’Sullivan, Judith Runnels, PhD, Yu-Tsu Tai, PhD, Steven Treon, MD, Teru Hideshima, MD, Kenneth Anderson, MD, Irene Ghobrial, MD

Blood (2006) 108 (11): 2416.

https://doi.org/10.1182/blood.V108.11.2416.2416

Published: 2006

Journal Articles

Bcl2 Associated Induction of the Suppressor of Cytokine Signaling-3 (SOCS3) Gene Involves Activation of the p44/42 MAPK Pathway.

Julie Kim, MD, PhD, Sofya Rodov, Jacqueline Barrientos, MD, Ravitharan Krishnadasan, MD, K. Gary J. Vanasse, MD

Blood (2005) 106 (11): 2286.

https://doi.org/10.1182/blood.V106.11.2286.2286

Published: 2005

NARROW

Zebrafish Xenotransplantation and Focused Chemical Genomics: A Preclinical Therapeutic Model For T-Cell Acute Lymphoblastic Leukemia

IGFBP7 Gene Promoting Cell Proliferation in Acute Myeloid Leukemia Through Activation of AKT3 and CCND1

Novel Recurrent Mutations in the Ras -Like GTP-Binding Gene Rit1 in Myeloid Malignancies

Inhibition of AKT Signaling Potently Inhibits the Growth of JAK and MPL-Mutant Cells in the Myeloproliferative Neoplasms In Vitro and In Vivo,

Effect of a Novel Nucleoside Analogue, Triciribine Phosphate (TCN-P) on Murine Acute Graft-Vrs-Host Disease (aGvHD)

Inhibition of AKT Signaling Potently Inhibits Growth of MPL-Mutant Cells in the Myeloproliferative Neoplasms.

The Role of the PI3K-AKT-mTOR Pathway in NK Cell Anti-Tumor Reactivity.

Phase I Study of the Akt-Inhibitor Triciribine Phosphate Monohydrate in Patients with Advanced Hematologic Malignancy

Rho-a and Rac-1 GTPases Play Major and Differential Roles in SDF1α- Induced Cell Adhesion and Chemotaxis in Multiple Myeloma.

BCL2 Induces Suppressor of Cytokine Signaling-3 (SOCS3) Expression in Murine B Cells Via Pathways Involving an HSP70/90 Complex and Activation of p44/42 Map Kinase.

Phase I Study of Triciribine Phosphate Monohydrate, a Specific Inhibitor of AKt Phosphorylation, in Adult Patients with Advanced Hematologic Malignancies.

Functional and Molecular Analysis of Oncogenic Pathways in Primary Myeloma Cells.

Molecular Mechanisms Regulating Resistance to the Akt Inhibitor Perifosine in Waldenstrom’s Macroglobulinemia, the Role of the ERK and PKC Pathways.

Bcl2 Associated Induction of the Suppressor of Cytokine Signaling-3 (SOCS3) Gene Involves Activation of the p44/42 MAPK Pathway.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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