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Journal Articles

A master erythroid regulator gets its own GPS

Lily Jun-shen Huang, James J. Bieker
Journal: Blood
Blood (2020) 135 (25): 2209–2210.
https://doi.org/10.1182/blood.2020005882
Published: 2020
Journal Articles

Acute Lymphoblastic Leukemia with Zinc-Finger Protein 384 (ZNF384)-Related Rearrangements: A Retrospective Analysis from the Ponte Di Legno Childhood ALL Working Group

Shinsuke Hirabayashi, Ellie Butler, Kentaro Ohki, MD PhD, Nobutaka Kiyokawa, MD PhD, Anke K. Bergmann, Judith M. Boer, PhD, Hélène Cavé, PharmD, PhD, Giovanni Cazzaniga, Allen Eng Juh Yeoh, Toshihiko Imamura, MD PhD, Hiroto Inaba, MD, Mignon L. Loh, MD, Ulrika Norén-Nyström, MD PhD, Agata Pastorczak, Lee-Yung Shih, MD, Marketa Zaliova, MD PhD, Oskar A Haas, Christine J. Harrison, PhD FRCPath, Anthony V. Moorman, Atsushi Manabe, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 652.
https://doi.org/10.1182/blood-2019-123236
Published: 2019
Journal Articles

Gfi1 Upregulates c-Myc Expression and Promotes c-Myc-Driven Cell Proliferation

Yangyang Zhang, MD, Fan Dong, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3769.
https://doi.org/10.1182/blood-2019-124833
Published: 2019
Journal Articles

Preliminary Results of a Phase 1/2 Clinical Study of Zinc Finger Nuclease-Mediated Editing of BCL11A in Autologous Hematopoietic Stem Cells for Transfusion-Dependent Beta Thalassemia

Angela R. Smith, MD MS, Gary J. Schiller, MD, Gregory M Vercellotti, MD, Janet L. Kwiatkowski, MD MSCE, Lakshmanan Krishnamurti, MD, Erica B. Esrick, MD, David A. Williams, MD, Weston P. Miller, MD, Adrian Woolfson, MD PhD, Mark C. Walters, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3544.
https://doi.org/10.1182/blood-2019-125743
Published: 2019
Journal Articles

GATA2 Zinc Finger Mutations Influence Erythroid Differentiation and Chemotherapy Response

Georg Leubolt, MSc, Enric Redondo Monte, MSc, BSc, Anja Wilding, MSc, Paul Kerbs, MSc, Monica Cusan, MD, Johannes Bagnoli, Wolfgang Enard, PhD, Wolfgang Hiddemann, MD PhD, Christian Wichmann, MD, Gunnar Schotta, PhD, Philipp A. Greif, MD PD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1459.
https://doi.org/10.1182/blood-2019-128218
Published: 2019
Journal Articles

Zinc Finger Nuclease-Mediated Disruption of the BCL11A Erythroid Enhancer Results in Enriched Biallelic Editing, Increased Fetal Hemoglobin, and Reduced Sickling in Erythroid Cells Derived from Sickle Cell Disease Patients

Samuel Lessard, PhD, Pauline Rimmele, PhD, Hui Ling, PhD, Kevin Moran, MSc, Benjamin Vieira, BS, Yi-Dong Lin, PhD, Vu Hong, PhD, Andreas Reik, PhD, Denny Dang, Naoya Uchida, MD, John F. Tisdale, MD, Pablo Rendo, MD, Ahmed Daak, PhD, Alexandra Hicks, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 974.
https://doi.org/10.1182/blood-2019-126048
Published: 2019
Journal Articles

Aberrant RNA Splicing Contributes to the Pathogenesis of EVI-Rearranged Myeloid Leukemias

Daichi Inoue, MD PhD, Stanley C Lee, PhD, Akihide Yoshimi, MD PhD, Justin Taylor, MD, Lillian E Bitner, BSc, Atsushi Tanaka, MD, Yasutaka Hayashi, MD PhD, Hana Cho, MSc, Chie Fukui, Ruth Saganty, Alexander V Penson, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 917.
https://doi.org/10.1182/blood-2019-124722
Published: 2019
Journal Articles

Exploiting the Zinc Finger Degrome Targeted By Lenalidomide to Engineer Reversible Off-Switch Degradable Chimeric Antigen Receptors

Max Jan, MD PhD, Ana Castano, MD, Amanda Walker, BA, Andrew A Guirguis, MD PhD, Jessica A Gasser, PhD, Amanda A Bouffard, Mikolaj Slabicki, PhD, Alexander Tepper, Daniel E Grinshpun, Taeyoon Kyung, PhD, Quinlan Sievers, MD PhD, Michael E Birnbaum, PhD, Marcela V Maus, MD PhD, Benjamin L. Ebert, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 866.
https://doi.org/10.1182/blood-2019-124210
Published: 2019
Journal Articles

Can Monosomy 7 be Targeted By Next Generation Cereblon-Modulating Agents?

Vera Adema, PhD, Cassandra M Kerr, MS, Wencke Walter, PhD, Stephan Hutter, PhD, Yasunobu Nagata, MD PhD, Hassan Awada, MD, Sunisa Kongkiatkamon, Christina A. Snider, BA, Milo Co, Rainey Magdalena, Arda Durmaz, Manja Meggendorfer, PhD, Aziz Nazha, MD, Jacob Scott, MD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Francesc Sole, PhD, Torsten Haferlach, MD, Valeria Visconte, PhD, Jaroslaw P. Maciejewski, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1270.
https://doi.org/10.1182/blood-2019-128967
Published: 2019
Journal Articles

The long and the short of it

David M. Bodine
Journal: Blood
Blood (2019) 134 (19): 1565–1566.
https://doi.org/10.1182/blood.2019002983
Published: 2019
Journal Articles

Zinc Finger Protein X-Linked Exhibits Pro-Leukemia Activity Via WNT3 in Chronic Myeloid Leukemia Stem/Progenitor Cells

Xiuyan Zhang, Yu Wang, Lun Xiao, Haixia Zhou, MD PhD, Li Zhu, MD PhD, Yun Zhao, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4247.
https://doi.org/10.1182/blood-2018-99-114663
Published: 2018
Journal Articles

KZF-L162R Mutation Affects Splenic Mature B Cell Development and Alters Expression of Aiolos Target Genes

Gregory Lazarian, Shanye Yin, PhD, Alba Font-tello, PhD, Elisa Ten Hacken, PhD, Tomasz Sevastianik, PhD, Daniel Tom, Fara Faye Regis, BS, Amy Gill, Mei Zheng, Katia Georgopoulos, PhD, Donna S Neuberg, ScD, Lili Wang, MDPhD, Ruben D. Carrasco, MD PhD, Catherine J. Wu, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 668.
https://doi.org/10.1182/blood-2018-99-115483
Published: 2018
Journal Articles

YY1 Controls Hematopoietic Stem Cell Quiescence By Repressing Cohesin Expression

Zhanping Lu, PhD, Anna L F. V. Assumpção, Aaron D Viny, MDMS, Ross L. Levine, MD, Xuan Pan, PhD DVM
Journal: Blood
Blood (2018) 132 (Supplement 1): 3831.
https://doi.org/10.1182/blood-2018-99-118679
Published: 2018
Journal Articles

GATA2 Zinc Finger Mutations Affect DNA-Binding and Promote Granulopoietic Differentiation

Georg Leubolt, MSc, Belay Tizazu, Sayantanee Dutta, PhD, Monica Cusan, MD, Theresa Sippenauer, Rouzanna Istvanffy, PhD, Robert A.J. Oostendorp, PhD, Wolfgang Hiddemann, Philipp A. Greif, MD PD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2779.
https://doi.org/10.1182/blood-2018-99-115976
Published: 2018
Journal Articles

The VWRPY Domain Is Essential for RUNX1 Function in Hematopoietic Progenitor Cell Maturation and Megakaryocyte Differentiation

Halah Alkadi, BSc, MSc, MT(ASCP), David McKellar, BS, Tao Zhen, PhD, Tatiana Karpova, PhD, Lisa J Garrett, MS, Yongxing Gao, MS, Anfal A Alsadhan, MS, Erika Mijin Kwon, PhD, James J Greene, PhD, David A Ball, PhD, Linzhao Cheng, PhD, April D Sorrell, MD, Paul P Liu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1319.
https://doi.org/10.1182/blood-2018-99-113400
Published: 2018
Journal Articles

Loss-of-function zinc finger mutation in the EGLN1 gene associated with erythrocytosis

Margje Sinnema, Daisheng Song, Wei Guan, Johanna W. H. Janssen, Richard van Wijk, Bradleigh E. Navalsky, Kai Peng, Albertine E. Donker, Alexander P. A. Stegmann, Frank S. Lee
Journal: Blood
Blood (2018) 132 (13): 1455–1458.
https://doi.org/10.1182/blood-2018-06-854711
Published: 2018
Journal Articles

Characterization of a HBB -Locus Fetal Chromatin Domain Region during Adult Erythropoiesis

Li Liu, PhD, Xingguo Zhu, PhD, Alexander Yu, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2223.
https://doi.org/10.1182/blood.V130.Suppl_1.2223.2223
Published: 2017
Journal Articles

Zebrafish gata2 Orthologs Are Necessary but Not Sufficient for Developmental Hematopoiesis

Oscar Pena, BS, MSc, Jasmine Rowell, BS, MS, Hanna Lemmik, BS, Chianna Umamahesan, BS, MSc, Catherine Hockings, MBBChir, MA, FRCPath, MRCP, Elspeth Payne, MDPhDFRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 3773.
https://doi.org/10.1182/blood.V130.Suppl_1.3773.3773
Published: 2017
Journal Articles

Early Growth Response (EGR)-1 Is a Key Regulator of Human Primary Bone Marrow Stroma Cells with a Dual Role in Proliferation and Hematopoietic Stroma Support Function

Hongzhe Li, PhD, Roshanak Ghazanfari, PhD, Hooi Ching Lim, PhD, Jenny Hansson, PhD, Dimitra Zacharaki, Stefan Scheding, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3777.
https://doi.org/10.1182/blood.V130.Suppl_1.3777.3777
Published: 2017
Journal Articles

Combined Analysis of Whole Exome Sequencing Data in Philadelphia-Negative Myeloproliferative (Ph-negative MPNs) and Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPNs) Reveals Novel Recurrently Mutated Genes

Fabio P S Santos, MD, Raquel MA Paiva, PhD, Renato D Puga, MSc, Giulliana AR Goncalves, MSc, Tarcila Santos Datoguia, MD, Welbert Oliveira, PhD, Bianca Lisboa, PhD, Ricardo Helman, MD PhD, Guilherme Perini, Nelson Hamerschlak, MD PhD, Paulo Vidal Campregher, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4224.
https://doi.org/10.1182/blood.V130.Suppl_1.4224.4224
Published: 2017