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Bruce R. Blazar
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Journal Articles

Autophagy prevents graft failure during murine graft-versus-host disease

Katie E. Lineburg, Lucie Leveque-El Mouttie, Christopher R. Hunter, Laetitia Le Texier, Crystal McGirr, Bianca Teal, Bruce R. Blazar, Steven W. Lane, Geoffrey R. Hill, Jean-Pierre Lévesque, Kelli P. A. MacDonald
Journal: Blood Advances
Blood Adv (2024) 8 (8): 2032–2043.
https://doi.org/10.1182/bloodadvances.2023010972
Published: 2024
Includes: Supplemental data
Journal Articles

Chronic GvHD NIH Consensus Project Biology Task Force: evolving path to personalized treatment of chronic GvHD

Nataliya P. Buxbaum, Gerard Socié, Geoffrey R. Hill, Kelli P. A. MacDonald, Victor Tkachev, Takanori Teshima, Stephanie J. Lee, Jerome Ritz, Stefanie Sarantopoulos, Leo Luznik, Defu Zeng, Sophie Paczesny, Paul J. Martin, Steven Z. Pavletic, Kirk R. Schultz, Bruce R. Blazar
Journal: Blood Advances
Blood Adv (2023) 7 (17): 4886–4902.
https://doi.org/10.1182/bloodadvances.2022007611
Published: 2023
Journal Articles

Clinical response to belumosudil in bronchiolitis obliterans syndrome: a combined analysis from 2 prospective trials

Clinical Trials & Observations
Zachariah DeFilipp, Haesook T. Kim, Zhongming Yang, John Noonan, Bruce R. Blazar, Stephanie J. Lee, Steven Z. Pavletic, Corey Cutler
Journal: Blood Advances
Blood Adv (2022) 6 (24): 6263–6270.
https://doi.org/10.1182/bloodadvances.2022008095
Published: 2022
Includes: Supplemental data
Journal Articles

Third-party type 2 innate lymphoid cells prevent and treat GI tract GvHD

Danny W. Bruce, Oleg Kolupaev, Sonia J. Laurie, Hemamalini Bommiasamy, Heather Stefanski, Bruce R. Blazar, James M. Coghill, Jonathan S. Serody
Journal: Blood Advances
Blood Adv (2021) 5 (22): 4578–4589.
https://doi.org/10.1182/bloodadvances.2020001514
Published: 2021
Includes: Supplemental data
Journal Articles

Activation status dictates the function of unlicensed natural killer cells in mice and humans

Ethan G. Aguilar, Cordelia Dunai, Sean J. Judge, Anthony E. Zamora, Lam T. Khuat, Logan V. Vick, Craig P. Collins, Kevin M. Stoffel, Maite Alvarez, Isabel Barao, Jeffrey S. Miller, Bruce R. Blazar, Patrice Chevallier, Christelle Retiere, Robert J. Canter, William J. Murphy
Journal: Blood Advances
Blood Adv (2021) 5 (20): 4219–4232.
https://doi.org/10.1182/bloodadvances.2021004589
Published: 2021
Includes: Supplemental data
Journal Articles

An irradiated marrow niche reveals a small noncollagenous protein mediator of homing, dermatopontin

Ashley C. Kramer, Yuliana Astuti, Alexis Elfstrum, Michael J. Lehrke, Jakub Tolar, Bruce R. Blazar, Amanda L. Blake, Mandy E. Taisto, Justin W. Furcich, Erin E. Nolan, Wilaiwan W. Durose, Beau R. Webber, Athena Geisness, David K. Wood, Troy C. Lund
Journal: Blood Advances
Blood Adv (2021) 5 (18): 3609–3622.
https://doi.org/10.1182/bloodadvances.2021004475
Published: 2021
Includes: Supplemental data
Journal Articles

First-in-human phase 1 trial of induced regulatory T cells for graft-versus-host disease prophylaxis in HLA-matched siblings

Clinical Trials & Observations
Margaret L. MacMillan, Keli L. Hippen, David H. McKenna, Diane Kadidlo, Darin Sumstad, Todd E. DeFor, Claudio G. Brunstein, Shernan G. Holtan, Jeffrey S. Miller, Erica D. Warlick, Daniel J. Weisdorf, John E. Wagner, Bruce R. Blazar
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1425–1436.
https://doi.org/10.1182/bloodadvances.2020003219
Published: 2021
Includes: Supplemental data
Journal Articles

Low-density PD-1 expression on resting human natural killer cells is functional and upregulated after transplantation

Zachary Davis, Martin Felices, Todd Lenvik, Sujan Badal, Joshua T. Walker, Peter Hinderlie, James L. Riley, Daniel A. Vallera, Bruce R. Blazar, Jeffrey S. Miller
Journal: Blood Advances
Blood Adv (2021) 5 (4): 1069–1080.
https://doi.org/10.1182/bloodadvances.2019001110
Published: 2021
Includes: Supplemental data
Journal Articles

Recipient-specific T-cell repertoire reconstitution in the gut following murine hematopoietic cell transplant

Pingping Zheng, John Tamaresis, Govindarajan Thangavelu, Liwen Xu, Xiaoqing You, Bruce R. Blazar, Robert S. Negrin, James L. Zehnder, Bettina P. Iliopoulou, Everett H. Meyer
Journal: Blood Advances
Blood Adv (2020) 4 (17): 4232–4243.
https://doi.org/10.1182/bloodadvances.2019000977
Published: 2020
Includes: Supplemental data
Journal Articles

Tissue mast cell counts may be associated with decreased severity of gastrointestinal acute GVHD and nonrelapse mortality

Clinical Trials & Observations
Celalettin Ustun, Todd E. DeFor, Fatma K. Karadag, Hyun Don Yun, Sunita Nathan, Claudio G. Brunstein, Bruce R. Blazar, Daniel J. Weisdorf, Shernan G. Holtan, Khalid Amin
Journal: Blood Advances
Blood Adv (2020) 4 (10): 2317–2324.
https://doi.org/10.1182/bloodadvances.2020001793
Published: 2020
Journal Articles

IL-2 enhances ex vivo–expanded regulatory T-cell persistence after adoptive transfer

Scott N. Furlan, Karnail Singh, Christina Lopez, Victor Tkachev, Daniel Joel Hunt, James Hibbard, Kayla M. Betz, Bruce R. Blazar, Cole Trapnell, Leslie S. Kean
Journal: Blood Advances
Blood Adv (2020) 4 (8): 1594–1605.
https://doi.org/10.1182/bloodadvances.2019001248
Published: 2020
Includes: Supplemental data
Journal Articles

Facilitating resolution of life-threatening acute GVHD with human chorionic gonadotropin and epidermal growth factor

Clinical Trials & Observations
Shernan G. Holtan, Andrea L. Hoeschen, Qing Cao, Mukta Arora, Veronika Bachanova, Claudio G. Brunstein, Jeffrey S. Miller, Armin Rashidi, Arne Slungaard, Celalettin Ustun, Gregory M. Vercellotti, Erica D. Warlick, Brian C. Betts, Najla El Jurdi, Fiona He, Chi Chen, Isha Gandhi, John E. Wagner, Bruce R. Blazar, Pamala Ann Jacobson, Ashraf Shabaneh, Jinhua Wang, Angela Panoskaltsis-Mortari, Margaret L. MacMillan, Daniel J. Weisdorf
Journal: Blood Advances
Blood Adv (2020) 4 (7): 1284–1295.
https://doi.org/10.1182/bloodadvances.2019001259
Published: 2020
Includes: Supplemental data
Journal Articles

Generation and function of progenitor T cells from StemRegenin-1–expanded CD34 + human hematopoietic progenitor cells

Jastaranpreet Singh, Edward L. Y. Chen, Yan Xing, Heather E. Stefanski, Bruce R. Blazar, Juan Carlos Zúñiga-Pflücker
Journal: Blood Advances
Blood Adv (2019) 3 (20): 2934–2948.
https://doi.org/10.1182/bloodadvances.2018026575
Published: 2019
Includes: Supplemental data
Journal Articles

Dose-escalated interleukin-2 therapy for refractory chronic graft-versus-host disease in adults and children

Clinical Trials & Observations
Jennifer S. Whangbo, Haesook T. Kim, Nikola Mirkovic, Lauren Leonard, Samuel Poryanda, Sophie Silverstein, Soomin Kim, Carol G. Reynolds, Sharmila C. Rai, Kelly Verrill, Michelle A. Lee, Steven Margossian, Christine Duncan, Leslie Lehmann, Jennifer Huang, Sarah Nikiforow, Edwin P. Alyea, III, Philippe Armand, Corey S. Cutler, Vincent T. Ho, Bruce R. Blazar, Joseph H. Antin, Robert J. Soiffer, Jerome Ritz, John Koreth
Journal: Blood Advances
Blood Adv (2019) 3 (17): 2550–2561.
https://doi.org/10.1182/bloodadvances.2019000631
Published: 2019
Includes: Supplemental data
Journal Articles

First-in-human trial of rhIL-15 and haploidentical natural killer cell therapy for advanced acute myeloid leukemia

Clinical Trials & Observations
Sarah Cooley, Fiona He, Veronika Bachanova, Gregory M. Vercellotti, Todd E. DeFor, Julie M. Curtsinger, Paul Robertson, Bartosz Grzywacz, Kevin C. Conlon, Thomas A. Waldmann, David H. McKenna, Bruce R. Blazar, Daniel J. Weisdorf, Jeffrey S. Miller
Journal: Blood Advances
Blood Adv (2019) 3 (13): 1970–1980.
https://doi.org/10.1182/bloodadvances.2018028332
Published: 2019
Includes: Supplemental data
Journal Articles

Efficacy and immunologic effects of extracorporeal photopheresis plus interleukin-2 in chronic graft-versus-host disease

Clinical Trials & Observations
Roger Belizaire, Haesook T. Kim, Samuel J. Poryanda, Nikola V. Mirkovic, Evelyn Hipolito, William J. Savage, Carol G. Reynolds, Marie J. Fields, Jennifer Whangbo, Tomohiro Kubo, Sarah Nikiforow, Edwin P. Alyea, Philippe Armand, Corey S. Cutler, Vincent T. Ho, Bruce R. Blazar, Joseph H. Antin, Jerome Ritz, Robert J. Soiffer, John Koreth
Journal: Blood Advances
Blood Adv (2019) 3 (7): 969–979.
https://doi.org/10.1182/bloodadvances.2018029124
Published: 2019
Includes: Supplemental data
Journal Articles

Impaired bone marrow B-cell development in mice with a bronchiolitis obliterans model of cGVHD

Oleg V. Kolupaev, Trisha A. Dant, Hemamalini Bommiasamy, Danny W. Bruce, Kenneth A. Fowler, Stephen L. Tilley, Karen P. McKinnon, Stefanie Sarantopoulos, Bruce R. Blazar, James M. Coghill, Jonathan S. Serody
Journal: Blood Advances
Blood Adv (2018) 2 (18): 2307–2319.
https://doi.org/10.1182/bloodadvances.2017014977
Published: 2018
Includes: Supplemental data
Journal Articles

How ibrutinib, a B-cell malignancy drug, became an FDA-approved second-line therapy for steroid-resistant chronic GVHD

Clinical Trials & Observations
Samantha M. Jaglowski, Bruce R. Blazar
Journal: Blood Advances
Blood Adv (2018) 2 (15): 2012–2019.
https://doi.org/10.1182/bloodadvances.2018013060
Published: 2018
Journal Articles

Amphiregulin modifies the Minnesota Acute Graft-versus-Host Disease Risk Score: results from BMT CTN 0302/0802

Clinical Trials & Observations
Shernan G. Holtan, Todd E. DeFor, Angela Panoskaltsis-Mortari, Nandita Khera, John E. Levine, Mary E. D. Flowers, Stephanie J. Lee, Yoshihiro Inamoto, George L. Chen, Sebastian Mayer, Mukta Arora, Jeanne Palmer, Corey S. Cutler, Sally Arai, Aleksandr Lazaryan, Laura F. Newell, Madan H. Jagasia, Iskra Pusic, William A. Wood, Anne S. Renteria, Gregory Yanik, William J. Hogan, Elizabeth Hexner, Francis Ayuk, Ernst Holler, Udomsak Bunworasate, Yvonne A. Efebera, James L. M. Ferrara, Joseph Pidala, Alan Howard, Juan Wu, Javier Bolaños-Meade, Vincent Ho, Amin Alousi, Bruce R. Blazar, Daniel J. Weisdorf, Margaret L. MacMillan
Journal: Blood Advances
Blood Adv (2018) 2 (15): 1882–1888.
https://doi.org/10.1182/bloodadvances.2018017343
Published: 2018
Includes: Supplemental data
Journal Articles

161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS

Dhifaf Sarhan, Ludwig Brandt, Martin Felices, Karolin Guldevall, Todd Lenvik, Peter Hinderlie, Julie Curtsinger, Erica Warlick, Stephen R. Spellman, Bruce R. Blazar, Daniel J. Weisdorf, Sarah Cooley, Daniel A. Vallera, Björn Önfelt, Jeffrey S. Miller
Journal: Blood Advances
Blood Adv (2018) 2 (12): 1459–1469.
https://doi.org/10.1182/bloodadvances.2017012369
Published: 2018
Includes: Multimedia, Supplemental data