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Torsten Haferlach
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Journal Articles

Characterization of cases with the rare cytogenetic abnormality i(7)(p10) reveals an association with IDH2-mutated AML

Anna Stengel, Katharina Hörst, Constanze Kühn, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach
Journal: Blood Advances
Blood Adv (2024) 8 (15): 4125–4128.
https://doi.org/10.1182/bloodadvances.2024013225
Published: 2024
Includes: Supplemental data
Journal Articles

The E592K variant of SF3B1 creates unique RNA missplicing and associates with high-risk MDS without ring sideroblasts

In Young Choi, Jonathan P. Ling, Jian Zhang, Eric Helmenstine, Wencke Walter, Panagiotis Tsakiroglou, Riley E. Bergman, Céline Philippe, James L. Manley, Kevin Rouault-Pierre, Bing Li, Daniel H. Wiseman, Kiran Batta, Madhu Ouseph, Elsa Bernard, Benjamin Dubner, Xiao Li, Torsten Haferlach, Anna Koget, Salman Fazal, Tania Jain, Christopher D. Gocke, Amy E. DeZern, William Brian Dalton
Journal: Blood Advances
Blood Adv (2024) 8 (15): 3961–3971.
https://doi.org/10.1182/bloodadvances.2023011260
Published: 2024
Includes: Supplemental data
Journal Articles

Collaborative effect of Csnk1a1 haploinsufficiency and mutant p53 in Myc induction can promote leukemic transformation

Stijn N. R. Fuchs, Ursula S. A. Stalmann, Inge A. M. Snoeren, Eric Bindels, Stephani Schmitz, Bella Banjanin, Remco M. Hoogenboezem, Stanley van Herk, Mohamed Saad, Wencke Walter, Torsten Haferlach, Lancelot Seillier, Julio Saez-Rodriguez, Aurélien J. F. Dugourd, Kjong-Van Lehmann, Yinon Ben-Neriah, Hélène F. E. Gleitz, Rebekka K. Schneider
Journal: Blood Advances
Blood Adv (2024) 8 (3): 766–779.
https://doi.org/10.1182/bloodadvances.2022008926
Published: 2024
Includes: Supplemental data
Journal Articles

The clinical and genomic landscape of patients with DDX41 variants identified during diagnostic sequencing

Anna Maierhofer, Nikita Mehta, Ryan A. Chisholm, Stephan Hutter, Constance Baer, Niroshan Nadarajah, Christian Pohlkamp, Ella R. Thompson, Paul A. James, Wolfgang Kern, Claudia Haferlach, Manja Meggendorfer, Torsten Haferlach, Piers Blombery
Journal: Blood Advances
Blood Adv (2023) 7 (23): 7346–7357.
https://doi.org/10.1182/bloodadvances.2023011389
Published: 2023
Includes: Supplemental data
Journal Articles

Interplay of TP53 allelic state, blast count, and complex karyotype on survival of patients with AML and MDS

Anna Stengel, Manja Meggendorfer, Wencke Walter, Constance Baer, Niroshan Nadarajah, Stephan Hutter, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach
Journal: Blood Advances
Blood Adv (2023) 7 (18): 5540–5548.
https://doi.org/10.1182/bloodadvances.2023010312
Published: 2023
Journal Articles

How I read an article that uses machine learning methods

Aziz Nazha, Olivier Elemento, Shannon McWeeney, Moses Miles, Torsten Haferlach
Journal: Blood Advances
Blood Adv (2023) 7 (16): 4550–4554.
https://doi.org/10.1182/bloodadvances.2023010140
Published: 2023
Journal Articles

Specific subtype distribution with impact on prognosis of TP53 single-hit and double-hit events in AML and MDS

Anna Stengel, Torsten Haferlach, Constance Baer, Stephan Hutter, Manja Meggendorfer, Wolfgang Kern, Claudia Haferlach
Journal: Blood Advances
Blood Adv (2023) 7 (13): 2952–2956.
https://doi.org/10.1182/bloodadvances.2022009100
Published: 2023
Includes: Supplemental data
Journal Articles

TET2 mutations as a part of DNA dioxygenase deficiency in myelodysplastic syndromes

Carmelo Gurnari, Simona Pagliuca, Yihong Guan, Vera Adema, Courtney E. Hershberger, Ying Ni, Hassan Awada, Sunisa Kongkiatkamon, Misam Zawit, Diego F. Coutinho, Ilana R. Zalcberg, Jae-Sook Ahn, Hyeoung-Joon Kim, Dennis Dong Hwan Kim, Mark D. Minden, Joop H. Jansen, Manja Meggendorfer, Claudia Haferlach, Babal K. Jha, Torsten Haferlach, Jaroslaw P. Maciejewski, Valeria Visconte
Journal: Blood Advances
Blood Adv (2022) 6 (1): 100–107.
https://doi.org/10.1182/bloodadvances.2021005418
Published: 2022
Includes: Supplemental data
Journal Articles

Mutational patterns and their correlation to CHIP-related mutations and age in hematological malignancies

Anna Stengel, Constance Baer, Wencke Walter, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach
Journal: Blood Advances
Blood Adv (2021) 5 (21): 4426–4434.
https://doi.org/10.1182/bloodadvances.2021004668
Published: 2021
Includes: Supplemental data
Journal Articles

A geno-clinical decision model for the diagnosis of myelodysplastic syndromes

Clinical Trials & Observations
Nathan Radakovich, Manja Meggendorfer, Luca Malcovati, C. Beau Hilton, Mikkael A. Sekeres, Jacob Shreve, Yazan Rouphail, Wencke Walter, Stephan Hutter, Anna Galli, Sara Pozzi, Chiara Elena, Eric Padron, Michael R. Savona, Aaron T. Gerds, Sudipto Mukherjee, Yasunobu Nagata, Rami S. Komrokji, Babal K. Jha, Claudia Haferlach, Jaroslaw P. Maciejewski, Torsten Haferlach, Aziz Nazha
Journal: Blood Advances
Blood Adv (2021) 5 (21): 4361–4369.
https://doi.org/10.1182/bloodadvances.2021004755
Published: 2021
Includes: Supplemental data
Journal Articles

Splicing factor gene mutations in acute myeloid leukemia offer additive value if incorporated in current risk classification

Clinical Trials & Observations
Inge van der Werf, Anna Wojtuszkiewicz, Manja Meggendorfer, Stephan Hutter, Constance Baer, Martijn Heymans, Peter J. M. Valk, Wolfgang Kern, Claudia Haferlach, Jeroen J. W. M. Janssen, Gert J. Ossenkoppele, Jacqueline Cloos, Torsten Haferlach
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3254–3265.
https://doi.org/10.1182/bloodadvances.2021004556
Published: 2021
Includes: Supplemental data
Journal Articles

Whole transcriptome sequencing detects a large number of novel fusion transcripts in patients with AML and MDS

Anna Stengel, Rabia Shahswar, Torsten Haferlach, Wencke Walter, Stephan Hutter, Manja Meggendorfer, Wolfgang Kern, Claudia Haferlach
Journal: Blood Advances
Blood Adv (2020) 4 (21): 5393–5401.
https://doi.org/10.1182/bloodadvances.2020003007
Published: 2020
Includes: Supplemental data
Journal Articles

Treatment-free remission in FIP1L1-PDGFRA –positive myeloid/lymphoid neoplasms with eosinophilia after imatinib discontinuation

Clinical Trials & Observations
Georgia Metzgeroth, Juliana Schwaab, Nicole Naumann, Mohamad Jawhar, Torsten Haferlach, Alice Fabarius, Andreas Hochhaus, Wolf-Karsten Hofmann, Nicholas C. P. Cross, Andreas Reiter
Journal: Blood Advances
Blood Adv (2020) 4 (3): 440–443.
https://doi.org/10.1182/bloodadvances.2019001111
Published: 2020
Journal Articles

The ParaHox gene Cdx4 induces acute erythroid leukemia in mice

Silvia Thoene, Tamoghna Mandal, Naidu M. Vegi, Leticia Quintanilla-Martinez, Reinhild Rösler, Sebastian Wiese, Klaus H. Metzeler, Tobias Herold, Torsten Haferlach, Konstanze Döhner, Hartmut Döhner, Luisa Schwarzmüller, Ursula Klingmüller, Christian Buske, Vijay P. S. Rawat, Michaela Feuring-Buske
Journal: Blood Advances
Blood Adv (2019) 3 (22): 3729–3739.
https://doi.org/10.1182/bloodadvances.2019000761
Published: 2019
Includes: Supplemental data
Journal Articles

Invariant phenotype and molecular association of biallelic TET2 mutant myeloid neoplasia

Hassan Awada, Yasunobu Nagata, Abhinav Goyal, Mohammad F. Asad, Bhumika Patel, Cassandra M. Hirsch, Teodora Kuzmanovic, Yihong Guan, Bartlomiej P. Przychodzen, Mai Aly, Vera Adema, Wenyi Shen, Louis Williams, Aziz Nazha, Mohamed E. Abazeed, Mikkael A. Sekeres, Tomas Radivoyevitch, Torsten Haferlach, Babal K. Jha, Valeria Visconte, Jaroslaw P. Maciejewski
Journal: Blood Advances
Blood Adv (2019) 3 (3): 339–349.
https://doi.org/10.1182/bloodadvances.2018024216
Published: 2019
Includes: Supplemental data
Journal Articles

NPM1 mutated AML can relapse with wild-type NPM1 : persistent clonal hematopoiesis can drive relapse

Clinical Trials & Observations
Alexander Höllein, Manja Meggendorfer, Frank Dicker, Sabine Jeromin, Niroshan Nadarajah, Wolfgang Kern, Claudia Haferlach, Torsten Haferlach
Journal: Blood Advances
Blood Adv (2018) 2 (22): 3118–3125.
https://doi.org/10.1182/bloodadvances.2018023432
Published: 2018