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Journal Articles

FT-4202, an oral PKR activator, has potent antisickling effects and improves RBC survival and Hb levels in SCA mice

Archana Shrestha, Mengna Chi, Kimberly Wagner, Astha Malik, Jennifer Korpik, Adam Drake, Keertik Fulzele, Sylvie Guichard, Punam Malik
Journal: Blood Advances
Blood Adv (2021) 5 (9): 2385–2390.
https://doi.org/10.1182/bloodadvances.2020003604
Published: 2021
Includes: Supplemental data
Journal Articles

HRI depletion cooperates with pharmacologic inducers to elevate fetal hemoglobin and reduce sickle cell formation

Scott A. Peslak, Eugene Khandros, Peng Huang, Xianjiang Lan, Carly L. Geronimo, Jeremy D. Grevet, Osheiza Abdulmalik, Zhe Zhang, Belinda M. Giardine, Cheryl A. Keller, Junwei Shi, Ross C. Hardison, Gerd A. Blobel
Journal: Blood Advances
Blood Adv (2020) 4 (18): 4560–4572.
https://doi.org/10.1182/bloodadvances.2020002475
Published: 2020
Includes: Supplemental data
Journal Articles

Building access to care in adult sickle cell disease: defining models of care, essential components, and economic aspects

Julie Kanter, Wally R. Smith, Payal C. Desai, Marsha Treadwell, Biree Andemariam, Jane Little, Diane Nugent, Susan Claster, Deepa G. Manwani, Judith Baker, John J. Strouse, Ifeyinwa Osunkwo, Rosalyn W. Stewart, Allison King, Lisa M. Shook, John D. Roberts, Sophie Lanzkron
Journal: Blood Advances
Blood Adv (2020) 4 (16): 3804–3813.
https://doi.org/10.1182/bloodadvances.2020001743
Published: 2020
Journal Articles

Assessment of health-related quality of life among adults hospitalized with sickle cell disease vaso-occlusive crisis

Clinical Trials & Observations
Kimberly S. Esham, Angie Mae Rodday, Hedy P. Smith, Farzad Noubary, Ruth Ann Weidner, Rachel J. Buchsbaum, Susan K. Parsons
Journal: Blood Advances
Blood Adv (2019) 4 (1): 19–27.
https://doi.org/10.1182/bloodadvances.2019000128
Published: 2019
Journal Articles

Smooth muscle cytochrome b5 reductase 3 deficiency accelerates pulmonary hypertension development in sickle cell mice

Katherine C. Wood, Brittany G. Durgin, Heidi M. Schmidt, Scott A. Hahn, Jeffrey J. Baust, Tim Bachman, Dario A. Vitturi, Samit Ghosh, Solomon F. Ofori-Acquah, Ana L. Mora, Mark T. Gladwin, Adam C. Straub
Journal: Blood Advances
Blood Adv (2019) 3 (23): 4104–4116.
https://doi.org/10.1182/bloodadvances.2019000621
Published: 2019
Includes: Supplemental data
Journal Articles

Decoding the role of SOD2 in sickle cell disease

Atinuke M. Dosunmu-Ogunbi, Katherine C. Wood, Enrico M. Novelli, Adam C. Straub
Journal: Blood Advances
Blood Adv (2019) 3 (17): 2679–2687.
https://doi.org/10.1182/bloodadvances.2019000527
Published: 2019
Journal Articles

Height-corrected low bone density associates with severe outcomes in sickle cell disease: SCCRIP cohort study results

Clinical Trials & Observations
Oyebimpe O. Adesina, James G. Gurney, Guolian Kang, Martha Villavicencio, Jason R. Hodges, Wassim Chemaitilly, Sue C. Kaste, Babette S. Zemel, Jane S. Hankins
Journal: Blood Advances
Blood Adv (2019) 3 (9): 1476–1488.
https://doi.org/10.1182/bloodadvances.2018026047
Published: 2019
Includes: Supplemental data
Journal Articles

Hyperfiltration predicts long-term renal outcomes in humanized sickle cell mice

Malgorzata Kasztan, Brandon M. Fox, Jeffrey D. Lebensburger, Kelly A. Hyndman, Joshua S. Speed, Jennifer S. Pollock, David M. Pollock
Journal: Blood Advances
Blood Adv (2019) 3 (9): 1460–1475.
https://doi.org/10.1182/bloodadvances.2018028878
Published: 2019
Journal Articles

Metabolomic and molecular insights into sickle cell disease and innovative therapies

Morayo G. Adebiyi, Jeanne M. Manalo, Yang Xia
Journal: Blood Advances
Blood Adv (2019) 3 (8): 1347–1355.
https://doi.org/10.1182/bloodadvances.2018030619
Published: 2019
Journal Articles

Development of sickle cell diagnostics and a pediatric sickle cell clinic in Malawi

Portia Kamthunzi, Hillary Topazian, Tisungane Mvalo, Jane Chen, Isobel Kambalame, Pilirani Mafunga, Noel Mumba, Msandeni Chiume, Khadija Paseli, J. Brett Heimlich, Graham Ellis, Nigel Key, Satish Gopal, Irving Hoffman, Ken Ataga, Kate Westmoreland
Journal: Blood Advances
Blood Adv (2018) 2 (Supplement_1): 14–16.
https://doi.org/10.1182/bloodadvances.2018GS110913
Published: 2018
Journal Articles

Elevated ecto-5′-nucleotidase: a missing pathogenic factor and new therapeutic target for sickle cell disease

Hong Liu, Morayo Adebiyi, Rong Rong Liu, Anren Song, Jeanne Manalo, Yuan Edward Wen, Alexander Q. Wen, Tingting Weng, Junsuk Ko, Modupe Idowu, Rodney E. Kellems, Holger K. Eltzschig, Michael R. Blackburn, Harinder S. Juneja, Yang Xia
Journal: Blood Advances
Blood Adv (2018) 2 (15): 1957–1968.
https://doi.org/10.1182/bloodadvances.2018015784
Published: 2018
Includes: Supplemental data
Journal Articles

Double-blind, randomized, multicenter phase 2 study of SC411 in children with sickle cell disease (SCOT trial)

Clinical Trials & Observations
Ahmed A. Daak, Carlton D. Dampier, Beng Fuh, Julie Kanter, Ofelia A. Alvarez, L. Vandy Black, Melissa A. McNaull, Michael U. Callaghan, Alex George, Lynne Neumayr, Lee M. Hilliard, Fredrick Sancilio, Adrian L. Rabinowicz, Matthew M. Heeney
Journal: Blood Advances
Blood Adv (2018) 2 (15): 1969–1979.
https://doi.org/10.1182/bloodadvances.2018021444
Published: 2018
Includes: Supplemental data
Journal Articles

Randomized phase 2 trial of monthly vitamin D to prevent respiratory complications in children with sickle cell disease

Clinical Trials & Observations
Margaret T. Lee, Meyer Kattan, Ilene Fennoy, Stephen M. Arpadi, Rachel L. Miller, Serge Cremers, Donald J. McMahon, Jeri W. Nieves, Gary M. Brittenham
Journal: Blood Advances
Blood Adv (2018) 2 (9): 969–978.
https://doi.org/10.1182/bloodadvances.2017013979
Published: 2018
Includes: Supplemental data
Journal Articles

Manipulating hemoglobin oxygenation using silica nanoparticles: a novel prospect for artificial oxygen carriers

Stéphanie Devineau, Laurent Kiger, Frédéric Galacteros, Véronique Baudin-Creuza, Michael Marden, Jean Philippe Renault, Serge Pin
Journal: Blood Advances
Blood Adv (2018) 2 (2): 90–94.
https://doi.org/10.1182/bloodadvances.2017012153
Published: 2018
Includes: Supplemental data
Journal Articles

Alternative donor hematopoietic stem cell transplantation for sickle cell disease

Clinical Trials & Observations
Andrew L. Gilman, Michael J. Eckrich, Stacy Epstein, Carrie Barnhart, Mark Cannon, Tracy Fukes, Michelle Hyland, Krishna Shah, Darci Grochowski, Elizabeth Champion, Anastasia Ivanova
Journal: Blood Advances
Blood Adv (2017) 1 (16): 1215–1223.
https://doi.org/10.1182/bloodadvances.2017005462
Published: 2017