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Journal Articles

Frequent mutated B2M, EZH2 , IRF8 , and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype

Ruben A.L. de Groen, Ronald van Eijk, Stefan Böhringer, Tom van Wezel, Richard Raghoo, Dina Ruano, Patty M. Jansen, Inge Briaire-de Bruijn, Fleur A. de Groot, Karin Kleiverda, Liane te Boome, Valeska Terpstra, Henriette Levenga, Alina Nicolae, Eduardus F.M. Posthuma, Isabelle Focke-Snieders, Lizan Hardi, Wietske C.E. den Hartog, Lara H. Bohmer, Pancras C.W. Hogendoorn, Anke van den Berg, Arjan Diepstra, Marcel Nijland, Pieternella J. Lugtenburg, Marie José Kersten, Steven T. Pals, Hendrik Veelken, Judith V.M.G. Bovée, Arjen H.G. Cleven, Joost S.P. Vermaat
Journal: Blood Advances
Blood Adv (2021) 5 (19): 3760–3775.
https://doi.org/10.1182/bloodadvances.2021005215
Published: 2021
Includes: Supplemental data
Journal Articles

Molecular analysis of the erythroid phenotype of a patient with BCL11A haploinsufficiency

Clinical Trials & Observations
Marja W. Wessels, Marjon H. Cnossen, Thamar B. van Dijk, Nynke Gillemans, K. L. Juliëtte Schmidt, Kirsten van Lom, Divya S. Vinjamur, Steven Coyne, Ryo Kurita, Yukio Nakamura, Stella A. de Man, Rolph Pfundt, Zakia Azmani, Rutger W. W. Brouwer, Daniel E. Bauer, Mirjam C. G. N. van den Hout, Wilfred F. J. van IJcken, Sjaak Philipsen
Journal: Blood Advances
Blood Adv (2021) 5 (9): 2339–2349.
https://doi.org/10.1182/bloodadvances.2020003753
Published: 2021
Includes: Supplemental data
Journal Articles

Gene expression profile correlates with molecular and clinical features in patients with myelofibrosis

Clinical Trials & Observations
Sebastiano Rontauroli, Sara Castellano, Paola Guglielmelli, Roberta Zini, Elisa Bianchi, Elena Genovese, Chiara Carretta, Sandra Parenti, Sebastian Fantini, Selene Mallia, Lara Tavernari, Stefano Sartini, Margherita Mirabile, Carmela Mannarelli, Francesca Gesullo, Annalisa Pacilli, Daniela Pietra, Elisa Rumi, Silvia Salmoiraghi, Barbara Mora, Laura Villani, Andrea Grilli, Vittorio Rosti, Giovanni Barosi, Francesco Passamonti, Alessandro Rambaldi, Luca Malcovati, Mario Cazzola, Silvio Bicciato, Enrico Tagliafico, Alessandro M. Vannucchi, Rossella Manfredini
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1452–1462.
https://doi.org/10.1182/bloodadvances.2020003614
Published: 2021
Includes: Supplemental data
Journal Articles

Patients with triple-negative, JAK2 V617F- and CALR -mutated essential thrombocythemia share a unique gene expression signature

Samah Alimam, William Villiers, Richard Dillon, Michael Simpson, Manohursingh Runglall, Alexander Smith, Prodromos Chatzikyriakou, Paul Lavender, Anju Kanda, Ken Mills, Beatriz Bellosillo Paricio, James Kaufman-Cook, Sophie Ord, Shahram Kordasti, Deepti Radia, Claire Woodley, Yvonne Francis, Ghulam Mufti, Donal P. McLornan, Claire N. Harrison
Journal: Blood Advances
Blood Adv (2021) 5 (4): 1059–1068.
https://doi.org/10.1182/bloodadvances.2020003172
Published: 2021
Includes: Supplemental data
Journal Articles

Antitumor activity of the dual BET and CBP/EP300 inhibitor NEO2734

Filippo Spriano, Eugenio Gaudio, Luciano Cascione, Chiara Tarantelli, Federica Melle, Giovanna Motta, Valdemar Priebe, Andrea Rinaldi, Gaetanina Golino, Afua Adjeiwaa Mensah, Luca Aresu, Emanuele Zucca, Stefano Pileri, Michael Witcher, Bill Brown, Claes Wahlestedt, Francis Giles, Anastasios Stathis, Francesco Bertoni
Journal: Blood Advances
Blood Adv (2020) 4 (17): 4124–4135.
https://doi.org/10.1182/bloodadvances.2020001879
Published: 2020
Includes: Supplemental data
Journal Articles

Molecular background delineates outcome of double protein expressor diffuse large B-cell lymphoma

Clinical Trials & Observations
Leo Meriranta, Annika Pasanen, Amjad Alkodsi, Jari Haukka, Marja-Liisa Karjalainen-Lindsberg, Sirpa Leppä
Journal: Blood Advances
Blood Adv (2020) 4 (15): 3742–3753.
https://doi.org/10.1182/bloodadvances.2020001727
Published: 2020
Includes: Supplemental data
Journal Articles

Gene expression profiling of gray zone lymphoma

Clémentine Sarkozy, Lauren Chong, Katsuyoshi Takata, Elizabeth A. Chavez, Tomoko Miyata-Takata, Gerben Duns, Adèle Telenius, Merrill Boyle, Graham W. Slack, Camille Laurent, Pedro Farinha, Thierry J. Molina, Christiane Copie-Bergman, Diane Damotte, Gilles A. Salles, Anja Mottok, Kerry J. Savage, David W. Scott, Alexandra Traverse-Glehen, Christian Steidl
Journal: Blood Advances
Blood Adv (2020) 4 (11): 2523–2535.
https://doi.org/10.1182/bloodadvances.2020001923
Published: 2020
Includes: Supplemental data
Journal Articles

IL-2 enhances ex vivo–expanded regulatory T-cell persistence after adoptive transfer

Scott N. Furlan, Karnail Singh, Christina Lopez, Victor Tkachev, Daniel Joel Hunt, James Hibbard, Kayla M. Betz, Bruce R. Blazar, Cole Trapnell, Leslie S. Kean
Journal: Blood Advances
Blood Adv (2020) 4 (8): 1594–1605.
https://doi.org/10.1182/bloodadvances.2019001248
Published: 2020
Includes: Supplemental data
Journal Articles

Propranolol inhibits molecular risk markers in HCT recipients: a phase 2 randomized controlled biomarker trial

Clinical Trials & Observations
Jennifer M. Knight, J. Douglas Rizzo, Parameswaran Hari, Marcelo C. Pasquini, Karen E. Giles, Anita D’Souza, Brent R. Logan, Mehdi Hamadani, Saurabh Chhabra, Binod Dhakal, Nirav Shah, Deepika Sriram, Mary M. Horowitz, Steve W. Cole
Journal: Blood Advances
Blood Adv (2020) 4 (3): 467–476.
https://doi.org/10.1182/bloodadvances.2019000765
Published: 2020
Includes: Supplemental data
Journal Articles

E μ and 3′RR transcriptional enhancers of the IgH locus cooperate to promote c-myc–induced mature B-cell lymphomas

Nour Ghazzaui, Hussein Issaoui, Mélissa Ferrad, Claire Carrion, Jeanne Cook-Moreau, Yves Denizot, François Boyer
Journal: Blood Advances
Blood Adv (2020) 4 (1): 28–39.
https://doi.org/10.1182/bloodadvances.2019000845
Published: 2020
Includes: Supplemental data
Journal Articles

Circulating CD1c + myeloid dendritic cells are potential precursors to LCH lesion CD1a + CD207 + cells

Karen Phaik Har Lim, Paul Milne, Michael Poidinger, Kaibo Duan, Howard Lin, Naomi McGovern, Harshal Abhyankar, Daniel Zinn, Thomas M. Burke, Olive S. Eckstein, Rikhia Chakraborty, Amel Sengal, Brooks Scull, Evan Newell, Miriam Merad, Kenneth L. McClain, Tsz-Kwong Man, Florent Ginhoux, Matthew Collin, Carl E. Allen
Journal: Blood Advances
Blood Adv (2020) 4 (1): 87–99.
https://doi.org/10.1182/bloodadvances.2019000488
Published: 2020
Includes: Supplemental data
Journal Articles

Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia

Norio Shiba, Kenichi Yoshida, Yusuke Hara, Genki Yamato, Yuichi Shiraishi, Hidemasa Matsuo, Yusuke Okuno, Kenichi Chiba, Hiroko Tanaka, Taeko Kaburagi, Masanobu Takeuchi, Kentaro Ohki, Masashi Sanada, Jun Okubo, Daisuke Tomizawa, Tomohiko Taki, Akira Shimada, Manabu Sotomatsu, Keizo Horibe, Takashi Taga, Souichi Adachi, Akio Tawa, Satoru Miyano, Seishi Ogawa, Yasuhide Hayashi
Journal: Blood Advances
Blood Adv (2019) 3 (20): 3157–3169.
https://doi.org/10.1182/bloodadvances.2019000404
Published: 2019
Includes: Supplemental data
Journal Articles

Phf6-null hematopoietic stem cells have enhanced self-renewal capacity and oncogenic potentials

Yueh-Chwen Hsu, Tsung-Chih Chen, Chien-Chin Lin, Chang-Tsu Yuan, Chia-Lang Hsu, Hsin-An Hou, Chein-Jun Kao, Po-Han Chuang, Yu-Ren Chen, Wen-Chien Chou, Hwei-Fang Tien
Journal: Blood Advances
Blood Adv (2019) 3 (15): 2355–2367.
https://doi.org/10.1182/bloodadvances.2019000391
Published: 2019
Includes: Supplemental data
Journal Articles

Gene expression signature that predicts early molecular response failure in chronic-phase CML patients on frontline imatinib

Clinical Trials & Observations
Chung H. Kok, David T. Yeung, Liu Lu, Dale B. Watkins, Tamara M. Leclercq, Phuong Dang, Verity A. Saunders, John Reynolds, Deborah L. White, Timothy P. Hughes
Journal: Blood Advances
Blood Adv (2019) 3 (10): 1610–1621.
https://doi.org/10.1182/bloodadvances.2019000195
Published: 2019
Includes: Supplemental data
Journal Articles

Citron Rho-interacting kinase silencing causes cytokinesis failure and reduces tumor growth in multiple myeloma

Ilyas Sahin, Yawara Kawano, Romanos Sklavenitis-Pistofidis, Michele Moschetta, Yuji Mishima, Salomon Manier, Antonio Sacco, Ruben Carrasco, Rafael Fonseca, Aldo M. Roccaro, Thomas Witzig, Irene M. Ghobrial
Journal: Blood Advances
Blood Adv (2019) 3 (7): 995–1002.
https://doi.org/10.1182/bloodadvances.2018028456
Published: 2019
Includes: Supplemental data
Journal Articles

The nuclear receptor corepressor NCoR1 regulates hematopoiesis and leukemogenesis in vivo

Xiaoling Wan, Lulu Liu, Peipei Zhou, Xinhui Hui, Qiaomei He, Fangfang Yu, Wei Zhang, Xiaodan Ding, Xiujie Yuan, Na Zhang, Yingxi Zhao, Ruihong Zhu, Yuanhua Liu, Pei Hao, Johan Auwerx, Xianmin Song, Qibin Leng, Yan Zhang
Journal: Blood Advances
Blood Adv (2019) 3 (4): 644–657.
https://doi.org/10.1182/bloodadvances.2018022756
Published: 2019
Includes: Supplemental data
Journal Articles

The kinases IKBKE and TBK1 regulate MYC-dependent survival pathways through YB-1 in AML and are targets for therapy

Suhu Liu, Anna E. Marneth, Gabriela Alexe, Sarah R. Walker, Helen I. Gandler, Darwin Q. Ye, Katherine Labella, Radhika Mathur, Patricia A. Toniolo, Michelle Tillgren, Prafulla C. Gokhale, David Barbie, Ann Mullally, Kimberly Stegmaier, David A. Frank
Journal: Blood Advances
Blood Adv (2018) 2 (23): 3428–3442.
https://doi.org/10.1182/bloodadvances.2018016733
Published: 2018
Includes: Supplemental data
Journal Articles

Identification of IRF8 as a potent tumor suppressor in murine acute promyelocytic leukemia

Coline Gaillard, Sangeetha Surianarayanan, Trevor Bentley, Matthew R. Warr, Briana Fitch, Huimin Geng, Emmanuelle Passegué, Hugues de Thé, Scott C. Kogan
Journal: Blood Advances
Blood Adv (2018) 2 (19): 2462–2466.
https://doi.org/10.1182/bloodadvances.2018018929
Published: 2018
Includes: Supplemental data
Journal Articles

A multiple myeloma classification system that associates normal B-cell subset phenotypes with prognosis

Clinical Trials & Observations
Julie Støve Bødker, Rasmus Froberg Brøndum, Alexander Schmitz, Anna Amanda Schönherz, Ditte Starberg Jespersen, Mads Sønderkær, Charles Vesteghem, Hanne Due, Caroline Holm Nørgaard, Martin Perez-Andres, Mehmet Kemal Samur, Faith Davies, Brian Walker, Charlotte Pawlyn, Martin Kaiser, David Johnson, Uta Bertsch, Annemiek Broyl, Mark van Duin, Rajen Shah, Preben Johansen, Martin Agge Nørgaard, Richard J. Samworth, Pieter Sonneveld, Hartmut Goldschmidt, Gareth J. Morgan, Alberto Orfao, Nikhil Munshi, Hans Erik Johnsen, Tarec El-Galaly, Karen Dybkær, Martin Bøgsted
Journal: Blood Advances
Blood Adv (2018) 2 (18): 2400–2411.
https://doi.org/10.1182/bloodadvances.2018018564
Published: 2018
Includes: Supplemental data
Journal Articles

CXCR5 and ICOS expression identifies a CD8 T-cell subset with T FH features in Hodgkin lymphomas

Kieu-Suong Le, Patricia Amé-Thomas, Karin Tarte, Françoise Gondois-Rey, Samuel Granjeaud, Florence Orlanducci, Etienne D. Foucher, Florence Broussais, Reda Bouabdallah, Thierry Fest, Dominique Leroux, Sapna Yadavilli, Patrick A. Mayes, Luc Xerri, Daniel Olive
Journal: Blood Advances
Blood Adv (2018) 2 (15): 1889–1900.
https://doi.org/10.1182/bloodadvances.2018017244
Published: 2018
Includes: Supplemental data