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Journal Articles

RNA-seq–based miRNA signature as an independent predictor of relapse in pediatric B-cell acute lymphoblastic leukemia

Hirohito Kubota, Hiroo Ueno, Keiji Tasaka, Tomoya Isobe, Satoshi Saida, Itaru Kato, Katsutsugu Umeda, Mitsuteru Hiwatari, Daiichiro Hasegawa, Toshihiko Imamura, Nobuyuki Kakiuchi, Yasuhito Nannya, Seishi Ogawa, Hidefumi Hiramatsu, Junko Takita
Journal: Blood Advances
Blood Adv (2024) 8 (5): 1258–1271.
https://doi.org/10.1182/bloodadvances.2023011583
Published: 2024
Includes: Supplemental data
Journal Articles

Progenitor-like cell type of an MLL - EDC4 fusion in acute myeloid leukemia

Linda C. Schuster, Afzal P. Syed, Stephan M. Tirier, Simon Steiger, Isabelle Seufert, Heiko Becker, Jesus Duque-Afonso, Tobias Ma, Seishi Ogawa, Jan-Philipp Mallm, Michael Lübbert, Karsten Rippe
Journal: Blood Advances
Blood Adv (2023) 7 (22): 7079–7083.
https://doi.org/10.1182/bloodadvances.2022009096
Published: 2023
Includes: Supplemental data
Journal Articles

Postazacitidine clone size predicts long-term outcome of patients with myelodysplastic syndromes and related myeloid neoplasms

Clinical Trials & Observations
Yasuhito Nannya, Magnus Tobiasson, Shinya Sato, Elsa Bernard, Shigeki Ohtake, June Takeda, Maria Creignou, Lanying Zhao, Manabu Kusakabe, Yuhei Shibata, Nobuhiko Nakamura, Mizuki Watanabe, Nobuhiro Hiramoto, Yusuke Shiozawa, Yuichi Shiraishi, Hiroko Tanaka, Kenichi Yoshida, Nobuyuki Kakiuchi, Hideki Makishima, Masahiro Nakagawa, Kensuke Usuki, Mitsumasa Watanabe, Kazunori Imada, Hiroshi Handa, Masataka Taguchi, Toru Kiguchi, Kazuma Ohyashiki, Takayuki Ishikawa, Akifumi Takaori-Kondo, Hisashi Tsurumi, Senji Kasahara, Shigeru Chiba, Tomoki Naoe, Satoru Miyano, Elli Papaemanuil, Yasushi Miyazaki, Eva Hellström-Lindberg, Seishi Ogawa
Journal: Blood Advances
Blood Adv (2023) 7 (14): 3624–3636.
https://doi.org/10.1182/bloodadvances.2022009564
Published: 2023
Includes: Supplemental data
Journal Articles

Genome-wide DNA methylation analysis in pediatric acute myeloid leukemia

Genki Yamato, Tomoko Kawai, Norio Shiba, Junji Ikeda, Yusuke Hara, Kentaro Ohki, Shin-Ichi Tsujimoto, Taeko Kaburagi, Kenichi Yoshida, Yuichi Shiraishi, Satoru Miyano, Nobutaka Kiyokawa, Daisuke Tomizawa, Akira Shimada, Manabu Sotomatsu, Hirokazu Arakawa, Souichi Adachi, Takashi Taga, Keizo Horibe, Seishi Ogawa, Kenichiro Hata, Yasuhide Hayashi
Journal: Blood Advances
Blood Adv (2022) 6 (11): 3207–3219.
https://doi.org/10.1182/bloodadvances.2021005381
Published: 2022
Includes: Supplemental data
Journal Articles

Childhood acute myeloid leukemia with 5q deletion and HNRNPH1-MLLT10 fusion: the first case report

Ko Kudo, Yasuo Kubota, Tsutomu Toki, Rika Kanezaki, Akie Kobayashi, Tomohiko Sato, Takuya Kamio, Shinya Sasaki, Norio Shiba, Daisuke Tomizawa, Souichi Adachi, Kenichi Yoshida, Seishi Ogawa, Masafumi Seki, Junko Takita, Etsuro Ito, Kiminori Terui
Journal: Blood Advances
Blood Adv (2022) 6 (10): 3162–3166.
https://doi.org/10.1182/bloodadvances.2021006383
Published: 2022
Includes: Supplemental data
Journal Articles

Patient-specific MDS-RS iPSCs define the mis-spliced transcript repertoire and chromatin landscape of SF3B1 -mutant HSPCs

Georgios Asimomitis, André G. Deslauriers, Andriana G. Kotini, Elsa Bernard, Davide Esposito, Malgorzata Olszewska, Nikolaos Spyrou, Juan Arango Ossa, Teresa Mortera-Blanco, Richard Koche, Yasuhito Nannya, Luca Malcovati, Seishi Ogawa, Mario Cazzola, Stuart A. Aaronson, Eva Hellström-Lindberg, Elli Papaemmanuil, Eirini P. Papapetrou
Journal: Blood Advances
Blood Adv (2022) 6 (10): 2992–3005.
https://doi.org/10.1182/bloodadvances.2021006325
Published: 2022
Includes: Supplemental data
Journal Articles

NUDT15 variants confer high incidence of second malignancies in children with acute lymphoblastic leukemia

Clinical Trials & Observations
Masanori Yoshida, Kazuhiko Nakabayashi, Wentao Yang, Aiko Sato-Otsubo, Shin-ichi Tsujimoto, Hiroko Ogata-Kawata, Tomoko Kawai, Keisuke Ishiwata, Mika Sakamoto, Kohji Okamura, Kaoru Yoshida, Ryota Shirai, Tomoo Osumi, Takaya Moriyama, Rina Nishii, Hiroyuki Takahashi, Chikako Kiyotani, Yoko Shioda, Keita Terashima, Sae Ishimaru, Yuki Yuza, Masatoshi Takagi, Yuki Arakawa, Akitoshi Kinoshita, Moeko Hino, Toshihiko Imamura, Daisuke Hasegawa, Yozo Nakazawa, Mayuko Okuya, Harumi Kakuda, Nao Takasugi, Akiko Inoue, Kentaro Ohki, Takako Yoshioka, Shuichi Ito, Daisuke Tomizawa, Katsuyoshi Koh, Kimikazu Matsumoto, Masashi Sanada, Nobutaka Kiyokawa, Akira Ohara, Seishi Ogawa, Atsushi Manabe, Akira Niwa, Kenichiro Hata, Jun J. Yang, Motohiro Kato
Journal: Blood Advances
Blood Adv (2021) 5 (23): 5420–5428.
https://doi.org/10.1182/bloodadvances.2021005507
Published: 2021
Includes: Supplemental data
Journal Articles

Landscape of driver mutations and their clinical impacts in pediatric B-cell precursor acute lymphoblastic leukemia

Hiroo Ueno, Kenichi Yoshida, Yusuke Shiozawa, Yasuhito Nannya, Yuka Iijima-Yamashita, Nobutaka Kiyokawa, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Tomoya Isobe, Masafumi Seki, Shunsuke Kimura, Hideki Makishima, Masahiro M. Nakagawa, Nobuyuki Kakiuchi, Keisuke Kataoka, Tetsuichi Yoshizato, Dai Nishijima, Takao Deguchi, Kentaro Ohki, Atsushi Sato, Hiroyuki Takahashi, Yoshiko Hashii, Sadao Tokimasa, Junichi Hara, Yoshiyuki Kosaka, Koji Kato, Takeshi Inukai, Junko Takita, Toshihiko Imamura, Satoru Miyano, Atsushi Manabe, Keizo Horibe, Seishi Ogawa, Masashi Sanada
Journal: Blood Advances
Blood Adv (2020) 4 (20): 5165–5173.
https://doi.org/10.1182/bloodadvances.2019001307
Published: 2020
Includes: Supplemental data
Journal Articles

Fusion partner–specific mutation profiles and KRAS mutations as adverse prognostic factors in MLL -rearranged AML

Hidemasa Matsuo, Kenichi Yoshida, Kana Nakatani, Yutarou Harata, Moe Higashitani, Yuri Ito, Yasuhiko Kamikubo, Yusuke Shiozawa, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Ai Okada, Yasuhito Nannya, June Takeda, Hiroo Ueno, Nobutaka Kiyokawa, Daisuke Tomizawa, Takashi Taga, Akio Tawa, Satoru Miyano, Manja Meggendorfer, Claudia Haferlach, Seishi Ogawa, Souichi Adachi
Journal: Blood Advances
Blood Adv (2020) 4 (19): 4623–4631.
https://doi.org/10.1182/bloodadvances.2020002457
Published: 2020
Includes: Supplemental data
Journal Articles

Molecular pathogenesis of progression to myeloid leukemia from TET-insufficient status

Raksha Shrestha, Mamiko Sakata-Yanagimoto, Koichiro Maie, Motohiko Oshima, Masatomo Ishihara, Yasuhito Suehara, Kota Fukumoto, Yaeko Nakajima-Takagi, Hirotaka Matsui, Takayasu Kato, Hideharu Muto, Tatsuhiro Sakamoto, Manabu Kusakabe, Yasuhito Nannya, Hideki Makishima, Hiroo Ueno, Ryunosuke Saiki, Seishi Ogawa, Kenichi Chiba, Yuichi Shiraishi, Satoru Miyano, Enguerran Mouly, Olivier A. Bernard, Toshiya Inaba, Haruhiko Koseki, Atsushi Iwama, Shigeru Chiba
Journal: Blood Advances
Blood Adv (2020) 4 (5): 845–854.
https://doi.org/10.1182/bloodadvances.2019001324
Published: 2020
Includes: Supplemental data
Journal Articles

Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia

Norio Shiba, Kenichi Yoshida, Yusuke Hara, Genki Yamato, Yuichi Shiraishi, Hidemasa Matsuo, Yusuke Okuno, Kenichi Chiba, Hiroko Tanaka, Taeko Kaburagi, Masanobu Takeuchi, Kentaro Ohki, Masashi Sanada, Jun Okubo, Daisuke Tomizawa, Tomohiko Taki, Akira Shimada, Manabu Sotomatsu, Keizo Horibe, Takashi Taga, Souichi Adachi, Akio Tawa, Satoru Miyano, Seishi Ogawa, Yasuhide Hayashi
Journal: Blood Advances
Blood Adv (2019) 3 (20): 3157–3169.
https://doi.org/10.1182/bloodadvances.2019000404
Published: 2019
Includes: Supplemental data
Journal Articles

Ring sideroblasts in AML are associated with adverse risk characteristics and have a distinct gene expression pattern

Gerbrig Berger, Mylene Gerritsen, Guoqiang Yi, Theresia N. Koorenhof-Scheele, Leonie I. Kroeze, Marian Stevens-Kroef, Kenichi Yoshida, Yuichi Shiraishi, Eva van den Berg, Hein Schepers, Geert Huls, André B. Mulder, Seishi Ogawa, Joost H. A. Martens, Joop H. Jansen, Edo Vellenga
Journal: Blood Advances
Blood Adv (2019) 3 (20): 3111–3122.
https://doi.org/10.1182/bloodadvances.2019000518
Published: 2019
Includes: Supplemental data
Journal Articles

Identification of enhancer of mRNA decapping 4 as a novel fusion partner of MLL in acute myeloid leukemia

Heiko Becker, Gabriele Greve, Keisuke Kataoka, Jan-Philipp Mallm, Jesús Duque-Afonso, Tobias Ma, Christoph Niemöller, Milena Pantic, Justus Duyster, Michael L. Cleary, Julia Schüler, Karsten Rippe, Seishi Ogawa, Michael Lübbert
Journal: Blood Advances
Blood Adv (2019) 3 (5): 761–765.
https://doi.org/10.1182/bloodadvances.2018023879
Published: 2019
Includes: Supplemental data
Journal Articles

Frequent germline mutations of HAVCR2 in sporadic subcutaneous panniculitis-like T-cell lymphoma

Chantana Polprasert, Yasuhide Takeuchi, Nobuyuki Kakiuchi, Kenichi Yoshida, Thamathorn Assanasen, Wimonmas Sitthi, Udomsak Bunworasate, Arunrat Pirunsarn, Kitsada Wudhikarn, Panisinee Lawasut, Noppacharn Uaprasert, Sunisa Kongkiatkamon, Chatphatai Moonla, Masashi Sanada, Nobuhiro Akita, June Takeda, Yoichi Fujii, Hiromichi Suzuki, Yasuhito Nannya, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Ponlapat Rojnuckarin, Seishi Ogawa, Hideki Makishima
Journal: Blood Advances
Blood Adv (2019) 3 (4): 588–595.
https://doi.org/10.1182/bloodadvances.2018028340
Published: 2019
Includes: Supplemental data
Journal Articles

Recurrent CCND3 mutations in MLL -rearranged acute myeloid leukemia

Clinical Trials & Observations
Hidemasa Matsuo, Kenichi Yoshida, Kazutaka Fukumura, Kana Nakatani, Yuki Noguchi, Saho Takasaki, Mina Noura, Yusuke Shiozawa, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Ai Okada, Yasuhito Nannya, June Takeda, Hiroo Ueno, Norio Shiba, Genki Yamato, Hiroshi Handa, Yuichiro Ono, Nobuhiro Hiramoto, Takayuki Ishikawa, Kensuke Usuki, Ken Ishiyama, Shuichi Miyawaki, Hidehiro Itonaga, Yasushi Miyazaki, Machiko Kawamura, Hiroki Yamaguchi, Nobutaka Kiyokawa, Daisuke Tomizawa, Takashi Taga, Akio Tawa, Yasuhide Hayashi, Hiroyuki Mano, Satoru Miyano, Yasuhiko Kamikubo, Seishi Ogawa, Souichi Adachi
Journal: Blood Advances
Blood Adv (2018) 2 (21): 2879–2889.
https://doi.org/10.1182/bloodadvances.2018019398
Published: 2018
Includes: Supplemental data
Journal Articles

Sustained clonal hematopoiesis by HLA-lacking hematopoietic stem cells without driver mutations in aplastic anemia

Clinical Trials & Observations
Tatsuya Imi, Takamasa Katagiri, Kazuyoshi Hosomichi, Yoshitaka Zaimoku, Viet Hoang Nguyen, Noriharu Nakagawa, Atsushi Tajima, Tetsuichi Yoshizato, Seishi Ogawa, Shinji Nakao
Journal: Blood Advances
Blood Adv (2018) 2 (9): 1000–1012.
https://doi.org/10.1182/bloodadvances.2017013953
Published: 2018
Includes: Supplemental data