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Michael L. Cleary
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Journal Articles

Development of combination therapies with BTK inhibitors and dasatinib to treat CNS-infiltrating E2A-PBX1 + /preBCR + ALL

Gaia Gentile, Teresa Poggio, Antonella Catalano, Minna Voutilainen, Mari Lahnalampi, Marta Andrade-Martinez, Tobias Ma, Roman Sankowski, Lina Goncharenko, Stefan Tholen, Kyuho Han, David W. Morgens, Marco Prinz, Michael Lübbert, Sophia Engel, Tanja Nicole Hartmann, Gunnar Cario, Martin Schrappe, Lennart Lenk, Martin Stanulla, Justus Duyster, Peter Bronsert, Michael C. Bassik, Michael L. Cleary, Oliver Schilling, Merja Heinäniemi, Jesús Duque-Afonso
Journal: Blood Advances
Blood Adv (2024) 8 (11): 2846–2860.
https://doi.org/10.1182/bloodadvances.2023011582
Published: 2024
Includes: Supplemental data
Journal Articles

Age and ligand specificity influence the outcome of pathogen engagement on preleukemic and leukemic B-cell precursor populations

Tanmaya Atre, Ali Farrokhi, Sumin Jo, Samuel Salitra, Jesus Duque-Afonso, Michael L. Cleary, Nina Rolf, Gregor S. D. Reid
Journal: Blood Advances
Blood Adv (2023) 7 (22): 7087–7099.
https://doi.org/10.1182/bloodadvances.2023010782
Published: 2023
Includes: Supplemental data
Journal Articles

Enhancer remodeling drives MLL oncogene-dependent transcriptional dysregulation in leukemia stem cells

Feng Pan, Masayuki Iwasaki, Wenqi Wu, Yanan Jiang, Xin Yang, Li Zhu, Zhigang Zhao, Michael L. Cleary
Journal: Blood Advances
Blood Adv (2023) 7 (11): 2504–2519.
https://doi.org/10.1182/bloodadvances.2022008787
Published: 2023
Includes: Supplemental data
Journal Articles

High-efficiency CRISPR induction of t(9;11) chromosomal translocations and acute leukemias in human blood stem cells

Johan Jeong, Astraea Jager, Pablo Domizi, Mara Pavel-Dinu, Linda Gojenola, Masayuki Iwasaki, Michael C. Wei, Feng Pan, James L. Zehnder, Matthew H. Porteus, Kara L. Davis, Michael L. Cleary
Journal: Blood Advances
Blood Adv (2019) 3 (19): 2825–2835.
https://doi.org/10.1182/bloodadvances.2019000450
Published: 2019
Includes: Supplemental data
Journal Articles

Identification of enhancer of mRNA decapping 4 as a novel fusion partner of MLL in acute myeloid leukemia

Heiko Becker, Gabriele Greve, Keisuke Kataoka, Jan-Philipp Mallm, Jesús Duque-Afonso, Tobias Ma, Christoph Niemöller, Milena Pantic, Justus Duyster, Michael L. Cleary, Julia Schüler, Karsten Rippe, Seishi Ogawa, Michael Lübbert
Journal: Blood Advances
Blood Adv (2019) 3 (5): 761–765.
https://doi.org/10.1182/bloodadvances.2018023879
Published: 2019
Includes: Supplemental data
Journal Articles

MLL leukemia induction by t(9;11) chromosomal translocation in human hematopoietic stem cells using genome editing

Corina Schneidawind, Johan Jeong, Dominik Schneidawind, In-Suk Kim, Jesús Duque-Afonso, Stephen Hon Kit Wong, Masayuki Iwasaki, Erin H. Breese, James L. Zehnder, Matthew Porteus, Michael L. Cleary
Journal: Blood Advances
Blood Adv (2018) 2 (8): 832–845.
https://doi.org/10.1182/bloodadvances.2017013748
Published: 2018
Includes: Supplemental data