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Journal Articles

Preclinical evaluation of immunotherapeutic regimens for fetal/neonatal alloimmune thrombocytopenia

Huiying Zhi, Maria T. Ahlen, Björn Skogen, Debra K. Newman, Peter J. Newman

Blood Adv (2021) 5 (18): 3552–3562.

https://doi.org/10.1182/bloodadvances.2021004371

Published: 2021

Includes: Supplemental data

Journal Articles

CRISPR-edited megakaryocytes for rapid screening of platelet gene functions

Emilie Montenont, Seema Bhatlekar, Shancy Jacob, Yasuhiro Kosaka, Bhanu K. Manne, Olivia Lee, Ivan Parra-Izquierdo, Emilia Tugolukova, Neal D. Tolley, Matthew T. Rondina, Paul F. Bray, Jesse W. Rowley

Blood Adv (2021) 5 (9): 2362–2374.

https://doi.org/10.1182/bloodadvances.2020004112

Published: 2021

Includes: Supplemental data

Journal Articles

Electron microscopy shows that binding of monoclonal antibody PT25-2 primes integrin αIIbβ3 for ligand binding

Dragana Nešić, Martin Bush, Aleksandar Spasic, Jihong Li, Tetsuji Kamata, Makoto Handa, Marta Filizola, Thomas Walz, Barry S. Coller

Blood Adv (2021) 5 (7): 1781–1790.

https://doi.org/10.1182/bloodadvances.2020004166

Published: 2021

Includes: Supplemental data

Journal Articles

Loss of the exocyst complex component EXOC3 promotes hemostasis and accelerates arterial thrombosis

Tony G. Walsh, Yong Li, Christopher M. Williams, Elizabeth W. Aitken, Robert K. Andrews, Alastair W. Poole

Blood Adv (2021) 5 (3): 674–686.

https://doi.org/10.1182/bloodadvances.2020002515

Published: 2021

Includes: Supplemental data

Journal Articles

Integrin VLA-4 as a PET imaging biomarker of hyper-adhesion in transgenic sickle mice

Lydia A. Perkins, Lea Nyiranshuti, Lynda Little-Ihrig, Joseph D. Latoche, Kathryn E. Day, Qin Zhu, Sina Tavakoli, Prithu Sundd, Enrico M. Novelli, Carolyn J. Anderson

Blood Adv (2020) 4 (17): 4102–4112.

https://doi.org/10.1182/bloodadvances.2020002642

Published: 2020

Includes: Supplemental data

Journal Articles

Neutrophils lacking ERM proteins polarize and crawl directionally but have decreased adhesion strength

Sumith R. Panicker, Tadayuki Yago, Bojing Shao, Rodger P. McEver

Blood Adv (2020) 4 (15): 3559–3571.

https://doi.org/10.1182/bloodadvances.2020002423

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Structure basis of the FERM domain of kindlin-3 in supporting integrin αIIbβ3 activation in platelets

Jiaojiao Sun, Desheng Xiao, Yuan Ni, Tianlong Zhang, Zhongyuan Cao, Zhou Xu, Huong Nguyen, Jun Zhang, Gilbert C. White, Jianping Ding, Yan-Qing Ma, Zhen Xu

Blood Adv (2020) 4 (13): 3128–3135.

https://doi.org/10.1182/bloodadvances.2020001575

Published: 2020

Includes: Supplemental data

Journal Articles

The EGFL7-ITGB3-KLF2 axis enhances survival of multiple myeloma in preclinical models

Yousef Salama, Andries Hendrik Heida, Kazuaki Yokoyama, Satoshi Takahashi, Koichi Hattori, Beate Heissig

Blood Adv (2020) 4 (6): 1021–1037.

https://doi.org/10.1182/bloodadvances.2019001002

Published: 2020

Includes: Supplemental data

Journal Articles

Ibrutinib, but not zanubrutinib, induces platelet receptor shedding of GPIb-IX-V complex and integrin α IIb β 3 in mice and humans

Gasim Dobie, Fahd A. Kuriri, Musab M. A. Omar, Fehaid Alanazi, Ali M. Gazwani, Chloe P. S. Tang, Daniel Man-yuen Sze, Sasanka M. Handunnetti, Constantine Tam, Denise E. Jackson

Blood Adv (2019) 3 (24): 4298–4311.

https://doi.org/10.1182/bloodadvances.2019000640

Published: 2019

Includes: Supplemental data

Journal Articles

α4β1 integrin associates with VEGFR2 in CLL cells and contributes to VEGF binding and intracellular signaling

Alejandra Gutiérrez-González, Noemí Aguilera-Montilla, Estefanía Ugarte-Berzal, Elvira Bailón, Isabel Cerro-Pardo, Clara Sánchez-Maroto, Lara García-Campillo, José A. García-Marco, Angeles García-Pardo

Blood Adv (2019) 3 (14): 2144–2148.

https://doi.org/10.1182/bloodadvances.2019000019

Published: 2019

Includes: Supplemental data

Journal Articles

Elimination of the fibrinogen integrin α M β 2 -binding motif improves renal pathology in mice with sickle cell anemia

Md Nasimuzzaman, Paritha I. Arumugam, Eric S. Mullins, Jeanne M. James, Katherine VandenHeuvel, Marilou G. Narciso, Maureen A. Shaw, Sarah McGraw, Bruce J. Aronow, Punam Malik

Blood Adv (2019) 3 (9): 1519–1532.

https://doi.org/10.1182/bloodadvances.2019032342

Published: 2019

Includes: Supplemental data

Journal Articles

Structural basis of the leukocyte integrin Mac-1 I-domain interactions with the platelet glycoprotein Ib

Juliet Morgan, Muhammad Saleem, Ruiqi Ng, Caroline Armstrong, Szu S. Wong, Simon G. Caulton, Alice Fickling, Huw E. L. Williams, Adam D. Munday, José A. López, Mark S. Searle, Jonas Emsley

Blood Adv (2019) 3 (9): 1450–1459.

https://doi.org/10.1182/bloodadvances.2018027011

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

ELMO1 deficiency enhances platelet function

Akruti Patel, John Kostyak, Carol Dangelmaier, Rachit Badolia, Dheeraj Bhavanasi, Joseph E. Aslan, Salim Merali, Soochong Kim, Johannes A. Eble, Lawrence Goldfinger, Satya Kunapuli

Blood Adv (2019) 3 (4): 575–587.

https://doi.org/10.1182/bloodadvances.2018016444

Published: 2019

Includes: Supplemental data

Journal Articles

Differential attenuation of β2 integrin–dependent and –independent neutrophil migration by Ly6G ligation

Pierre Cunin, Pui Y. Lee, Edy Kim, Angela B. Schmider, Nathalie Cloutier, Alexandre Pare, Matthias Gunzer, Roy J. Soberman, Steve Lacroix, Eric Boilard, Craig T. Lefort, Peter A. Nigrovic

Blood Adv (2019) 3 (3): 256–267.

https://doi.org/10.1182/bloodadvances.2018026732

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

Exosomal regulation of lymphocyte homing to the gut

Eun Jeong Park, Onmanee Prajuabjinda, Zay Yar Soe, Samuel Darkwah, Michael G. Appiah, Eiji Kawamoto, Fumiyasu Momose, Hiroshi Shiku, Motomu Shimaoka

Blood Adv (2018) 3 (1): 1–11.

https://doi.org/10.1182/bloodadvances.2018024877

Published: 2018

Includes: Supplemental data

Journal Articles

Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity

Praveen K. Suraneni, Seth J. Corey, Michael J. Hession, Rameez Ishaq, Arinola Awomolo, Shirin Hasan, Chirag Shah, Hui Liu, Amittha Wickrema, Najet Debili, John D. Crispino, Elizabeth A. Eklund, Yolande Chen

Blood Adv (2018) 2 (23): 3540–3552.

https://doi.org/10.1182/bloodadvances.2018021923

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

High-resolution mapping of the polyclonal immune response to the human platelet alloantigen HPA-1a (Pl A1 )

Huiying Zhi, Maria Therese Ahlen, Aye Myat Myat Thinn, Hartmut Weiler, Brian R. Curtis, Bjørn Skogen, Jieqing Zhu, Peter J. Newman

Blood Adv (2018) 2 (21): 3001–3011.

https://doi.org/10.1182/bloodadvances.2018023341

Published: 2018

Includes: Supplemental data

Journal Articles

Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation

Frederic Lagarrigue, Alexandre R. Gingras, David S. Paul, Andrew J. Valadez, Monica N. Cuevas, Hao Sun, Miguel A. Lopez-Ramirez, Benjamin T. Goult, Sanford J. Shattil, Wolfgang Bergmeier, Mark H. Ginsberg

Blood Adv (2018) 2 (18): 2358–2368.

https://doi.org/10.1182/bloodadvances.2018020487

Published: 2018

Includes: Supplemental data

Journal Articles

Platelet MEKK3 regulates arterial thrombosis and myocardial infarct expansion in mice

Xuemei Fan, Conghui Wang, Panlai Shi, Wen Gao, Jianmin Gu, Yan Geng, Wenlong Yang, Ningbo Wu, Yang Wang, Yanyan Xu, Xue Chen, Lin Zhang, Kemin Wang, Bing Su, Junling Liu

Blood Adv (2018) 2 (12): 1439–1448.

https://doi.org/10.1182/bloodadvances.2017015149

Published: 2018

Includes: Supplemental data

Journal Articles

Protein kinase C signaling dysfunction in von Willebrand disease (p.V1316M) type 2B platelets

Caterina Casari, David S. Paul, Sophie Susen, Cécile Lavenu-Bombled, Annie Harroche, Raymond Piatt, Kathryn O. Poe, Robert H. Lee, Marijke Bryckaert, Olivier D. Christophe, Peter J. Lenting, Cécile V. Denis, Wolfgang Bergmeier

Blood Adv (2018) 2 (12): 1417–1428.

https://doi.org/10.1182/bloodadvances.2017014290

Published: 2018

Includes: Supplemental data

NARROW

Preclinical evaluation of immunotherapeutic regimens for fetal/neonatal alloimmune thrombocytopenia

CRISPR-edited megakaryocytes for rapid screening of platelet gene functions

Electron microscopy shows that binding of monoclonal antibody PT25-2 primes integrin αIIbβ3 for ligand binding

Loss of the exocyst complex component EXOC3 promotes hemostasis and accelerates arterial thrombosis

Integrin VLA-4 as a PET imaging biomarker of hyper-adhesion in transgenic sickle mice

Neutrophils lacking ERM proteins polarize and crawl directionally but have decreased adhesion strength

Structure basis of the FERM domain of kindlin-3 in supporting integrin αIIbβ3 activation in platelets

The EGFL7-ITGB3-KLF2 axis enhances survival of multiple myeloma in preclinical models

Ibrutinib, but not zanubrutinib, induces platelet receptor shedding of GPIb-IX-V complex and integrin α IIb β 3 in mice and humans

α4β1 integrin associates with VEGFR2 in CLL cells and contributes to VEGF binding and intracellular signaling

Elimination of the fibrinogen integrin α M β 2 -binding motif improves renal pathology in mice with sickle cell anemia

Structural basis of the leukocyte integrin Mac-1 I-domain interactions with the platelet glycoprotein Ib

ELMO1 deficiency enhances platelet function

Differential attenuation of β2 integrin–dependent and –independent neutrophil migration by Ly6G ligation

Exosomal regulation of lymphocyte homing to the gut

Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity

High-resolution mapping of the polyclonal immune response to the human platelet alloantigen HPA-1a (Pl A1 )

Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation

Platelet MEKK3 regulates arterial thrombosis and myocardial infarct expansion in mice

Protein kinase C signaling dysfunction in von Willebrand disease (p.V1316M) type 2B platelets

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American Society of Hematology

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ASH Publications

American Society of Hematology

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