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Journal Articles

Single- and double-hit events in genes encoding immune targets before and after T cell–engaging antibody therapy in MM

Marietta S. Truger, Johannes Duell, Xiang Zhou, Larissa Heimeshoff, Anna Ruckdeschel, Mara John, Angela Riedel, Sebastian Hüper, Jessica Peter, Wencke Walter, Larissa Haertle, Manja Meggendorfer, Max S. Topp, Andreas Rosenwald, Matteo Claudio Da Via, Niccolo Bolli, Niels Weinhold, Hermann Einsele, Claudia Haferlach, K. Martin Kortüm, Leo Rasche
Journal: Blood Advances
Blood Adv (2021) 5 (19): 3794–3798.
https://doi.org/10.1182/bloodadvances.2021004418
Published: 2021
Includes: Supplemental data
Journal Articles

Lymphoid blast transformation in an MPN with BCR-JAK2 treated with ruxolitinib: putative mechanisms of resistance

Clinical Trials & Observations
Justin Anthony Chen, Yanli Hou, Krishna M. Roskin, Daniel A. Arber, Charles D. Bangs, Linda B. Baughn, Athena M. Cherry, Mark D. Ewalt, Andrew Z. Fire, Laure Fresard, Hutton M. Kearney, Stephen B. Montgomery, Robert S. Ohgami, Kathryn E. Pearce, Beth A. Pitel, Jason D. Merker, Jason Gotlib
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3492–3496.
https://doi.org/10.1182/bloodadvances.2020004174
Published: 2021
Includes: Supplemental data
Journal Articles

Development and characterization of prototypes for in vitro and in vivo mouse models of ibrutinib-resistant CLL

Burcu Aslan, Gorkem Kismali, Lisa S. Chen, LaKesla R. Iles, Mikhila Mahendra, Michael Peoples, Mihai Gagea, Natalie W. Fowlkes, Xiaofeng Zheng, Jing Wang, Christopher P. Vellano, Joseph R. Marszalek, Maria Teresa Sabrina Bertilaccio, Varsha Gandhi
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3134–3146.
https://doi.org/10.1182/bloodadvances.2020003821
Published: 2021
Includes: Supplemental data
Journal Articles

Arhgef2 regulates mitotic spindle orientation in hematopoietic stem cells and is essential for productive hematopoiesis

Derek C. H. Chan, Joshua Xu, Ana Vujovic, Nicholas Wong, Victor Gordon, Laura P. M. H. de Rooij, Steven Moreira, Cailin E. Joyce, Jose La Rose, María-José Sandí, Bradley W. Doble, Carl D. Novina, Robert K. Rottapel, Kristin J. Hope
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3120–3133.
https://doi.org/10.1182/bloodadvances.2020002539
Published: 2021
Includes: Supplemental data
Journal Articles

RPS15 mutations rewire RNA translation in chronic lymphocytic leukemia

Stavroula Ntoufa, Marina Gerousi, Stamatia Laidou, Fotis Psomopoulos, Georgios Tsiolas, Theodoros Moysiadis, Nikos Papakonstantinou, Larry Mansouri, Achilles Anagnostopoulos, Niki Stavrogianni, Sarka Pospisilova, Karla Plevova, Antonios M. Makris, Richard Rosenquist, Kostas Stamatopoulos
Journal: Blood Advances
Blood Adv (2021) 5 (13): 2788–2792.
https://doi.org/10.1182/bloodadvances.2020001717
Published: 2021
Includes: Supplemental data
Journal Articles

Gene expression signature predicts relapse in adult patients with cytogenetically normal acute myeloid leukemia

Clinical Trials & Observations
Christopher J. Walker, Krzysztof Mrózek, Hatice Gulcin Ozer, Deedra Nicolet, Jessica Kohlschmidt, Dimitrios Papaioannou, Luke K. Genutis, Marius Bill, Bayard L. Powell, Geoffrey L. Uy, Jonathan E. Kolitz, Andrew J. Carroll, Richard M. Stone, Ramiro Garzon, John C. Byrd, Ann-Kathrin Eisfeld, Albert de la Chapelle, Clara D. Bloomfield
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1474–1482.
https://doi.org/10.1182/bloodadvances.2020003727
Published: 2021
Includes: Supplemental data
Journal Articles

Patients with triple-negative, JAK2 V617F- and CALR -mutated essential thrombocythemia share a unique gene expression signature

Samah Alimam, William Villiers, Richard Dillon, Michael Simpson, Manohursingh Runglall, Alexander Smith, Prodromos Chatzikyriakou, Paul Lavender, Anju Kanda, Ken Mills, Beatriz Bellosillo Paricio, James Kaufman-Cook, Sophie Ord, Shahram Kordasti, Deepti Radia, Claire Woodley, Yvonne Francis, Ghulam Mufti, Donal P. McLornan, Claire N. Harrison
Journal: Blood Advances
Blood Adv (2021) 5 (4): 1059–1068.
https://doi.org/10.1182/bloodadvances.2020003172
Published: 2021
Includes: Supplemental data
Journal Articles

Diversity of peripheral blood human NK cells identified by single-cell RNA sequencing

Samantha L. Smith, Philippa R. Kennedy, Kevin B. Stacey, Jonathan D. Worboys, Annie Yarwood, Seungmae Seo, Everardo Hegewisch Solloa, Brandon Mistretta, Sujash S. Chatterjee, Preethi Gunaratne, Kimaada Allette, Ying-Chih Wang, Melissa Laird Smith, Robert Sebra, Emily M. Mace, Amir Horowitz, Wendy Thomson, Paul Martin, Steve Eyre, Daniel M. Davis
Journal: Blood Advances
Blood Adv (2020) 4 (7): 1388–1406.
https://doi.org/10.1182/bloodadvances.2019000699
Published: 2020
Includes: Supplemental data
Journal Articles

Coexpression of FOXP3 and a Helios isoform enhances the effectiveness of human engineered regulatory T cells

Amara Seng, Kelsey L. Krausz, Dong Pei, Devin C. Koestler, Ryan T. Fischer, Thomas M. Yankee, Mary A. Markiewicz
Journal: Blood Advances
Blood Adv (2020) 4 (7): 1325–1339.
https://doi.org/10.1182/bloodadvances.2019000965
Published: 2020
Includes: Supplemental data
Journal Articles

Brown LM, Lonsdale A, Zhu A, et al. The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia. Blood Adv. 2020;4(5):930-942.

Journal: Blood Advances
Blood Adv (2020) 4 (7): 1217.
https://doi.org/10.1182/bloodadvances.2020001859
Published: 2020
Journal Articles

Thrombotic, inflammatory, and HIF-regulated genes and thrombosis risk in polycythemia vera and essential thrombocythemia

Radhika Gangaraju, Jihyun Song, Soo Jin Kim, Tsewang Tashi, Brandi N. Reeves, Krishna M. Sundar, Perumal Thiagarajan, Josef T. Prchal
Journal: Blood Advances
Blood Adv (2020) 4 (6): 1115–1130.
https://doi.org/10.1182/bloodadvances.2019001379
Published: 2020
Journal Articles

Comprehensive metagenomic analysis of blastic plasmacytoid dendritic cell neoplasm

Jason Nomburg, Susan Bullman, Sun Sook Chung, Katsuhiro Togami, Mark A. Walker, Gabriel K. Griffin, Elizabeth A. Morgan, Nicole R. LeBoeuf, James A. DeCaprio, Matthew Meyerson, Andrew A. Lane
Journal: Blood Advances
Blood Adv (2020) 4 (6): 1006–1011.
https://doi.org/10.1182/bloodadvances.2019001260
Published: 2020
Includes: Supplemental data
Journal Articles

The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia

Lauren M. Brown, Andrew Lonsdale, Andrea Zhu, Nadia M. Davidson, Breon Schmidt, Anthony Hawkins, Elise Wallach, Michelle Martin, Francoise M. Mechinaud, Seong Lin Khaw, Ray C. Bartolo, Louise E. A. Ludlow, Jackie Challis, Ian Brooks, Vida Petrovic, Nicola C. Venn, Rosemary Sutton, Ian J. Majewski, Alicia Oshlack, Paul G. Ekert
Journal: Blood Advances
Blood Adv (2020) 4 (5): 930–942.
https://doi.org/10.1182/bloodadvances.2019001008
Published: 2020
Includes: Supplemental data
Journal Articles

Integrative analysis of the genomic and transcriptomic landscape of double-refractory multiple myeloma

Bachisio Ziccheddu, Giulia Biancon, Filippo Bagnoli, Chiara De Philippis, Francesco Maura, Even H. Rustad, Matteo Dugo, Andrea Devecchi, Loris De Cecco, Marialuisa Sensi, Carolina Terragna, Marina Martello, Tina Bagratuni, Efstathios Kastritis, Meletios A. Dimopoulos, Michele Cavo, Cristiana Carniti, Vittorio Montefusco, Paolo Corradini, Niccolo Bolli
Journal: Blood Advances
Blood Adv (2020) 4 (5): 830–844.
https://doi.org/10.1182/bloodadvances.2019000779
Published: 2020
Includes: Supplemental data
Journal Articles

Mutation accumulation in cancer genes relates to nonoptimal outcome in chronic myeloid leukemia

Clinical Trials & Observations
Shady Adnan Awad, Matti Kankainen, Teija Ojala, Perttu Koskenvesa, Samuli Eldfors, Bishwa Ghimire, Ashwini Kumar, Soili Kytölä, Mahmoud M. Kamel, Caroline A. Heckman, Kimmo Porkka, Satu Mustjoki
Journal: Blood Advances
Blood Adv (2020) 4 (3): 546–559.
https://doi.org/10.1182/bloodadvances.2019000943
Published: 2020
Includes: Supplemental data
Journal Articles

Highly multiplexed proteomic assessment of human bone marrow in acute myeloid leukemia

Haydar Çelik, Katherine E. Lindblad, Bogdan Popescu, Gege Gui, Meghali Goswami, Janet Valdez, Christin DeStefano, Catherine Lai, Julie Thompson, Jack Y. Ghannam, Giovanna Fantoni, Angélique Biancotto, Julián Candia, Foo Cheung, Gauthaman Sukumar, Clifton L. Dalgard, Richard H. Smith, Andre Larochelle, Laura W. Dillon, Christopher S. Hourigan
Journal: Blood Advances
Blood Adv (2020) 4 (2): 367–379.
https://doi.org/10.1182/bloodadvances.2019001124
Published: 2020
Includes: Supplemental data
Journal Articles

TAZ functions as a tumor suppressor in multiple myeloma by downregulating MYC

Stacy Grieve, Gabriel Wajnberg, Miranda Lees, Simi Chacko, Jackson Weir, Nicolas Crapoulet, Tony Reiman
Journal: Blood Advances
Blood Adv (2019) 3 (22): 3613–3625.
https://doi.org/10.1182/bloodadvances.2019000374
Published: 2019
Includes: Supplemental data
Journal Articles

Large-scale in vitro production of red blood cells from human peripheral blood mononuclear cells

Steven Heshusius, Esther Heideveld, Patrick Burger, Marijke Thiel-Valkhof, Erica Sellink, Eszter Varga, Elina Ovchynnikova, Anna Visser, Joost H. A. Martens, Marieke von Lindern, Emile van den Akker
Journal: Blood Advances
Blood Adv (2019) 3 (21): 3337–3350.
https://doi.org/10.1182/bloodadvances.2019000689
Published: 2019
Includes: Supplemental data
Journal Articles

Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia

Norio Shiba, Kenichi Yoshida, Yusuke Hara, Genki Yamato, Yuichi Shiraishi, Hidemasa Matsuo, Yusuke Okuno, Kenichi Chiba, Hiroko Tanaka, Taeko Kaburagi, Masanobu Takeuchi, Kentaro Ohki, Masashi Sanada, Jun Okubo, Daisuke Tomizawa, Tomohiko Taki, Akira Shimada, Manabu Sotomatsu, Keizo Horibe, Takashi Taga, Souichi Adachi, Akio Tawa, Satoru Miyano, Seishi Ogawa, Yasuhide Hayashi
Journal: Blood Advances
Blood Adv (2019) 3 (20): 3157–3169.
https://doi.org/10.1182/bloodadvances.2019000404
Published: 2019
Includes: Supplemental data
Journal Articles

Ring sideroblasts in AML are associated with adverse risk characteristics and have a distinct gene expression pattern

Gerbrig Berger, Mylene Gerritsen, Guoqiang Yi, Theresia N. Koorenhof-Scheele, Leonie I. Kroeze, Marian Stevens-Kroef, Kenichi Yoshida, Yuichi Shiraishi, Eva van den Berg, Hein Schepers, Geert Huls, André B. Mulder, Seishi Ogawa, Joost H. A. Martens, Joop H. Jansen, Edo Vellenga
Journal: Blood Advances
Blood Adv (2019) 3 (20): 3111–3122.
https://doi.org/10.1182/bloodadvances.2019000518
Published: 2019
Includes: Supplemental data