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Volume 2, Issue 4
November 2025
In Progress
Blood Neoplasia Cover Image for Volume 2, Issue 4

Volume 2 Issue 4 | Blood Neoplasia | American Society of Hematology

BASIC MECHANISMS OF NEOPLASIA

Olfactory receptors as tumor suppressors in cutaneous T-cell lymphoma via p38γ pathway modulation
Xu Hannah Zhang,Hongzhi Li,Jack Hsiang,Chih-Hong Chen,Sangkil Nam,Henry Wong,Xiwei Wu,Weidong Hu,Jack Shively,Steven T. Rosen
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CLINICAL TRIALS AND OBSERVATIONS

Tagraxofusp, a CD123-targeted therapy, for chronic myelomonocytic leukemia: final results of a phase 1/2 study
Clinical Trials & Observations
Mrinal M. Patnaik,Haris Ali,Eunice S. Wang,Abdulraheem Yacoub,James M. Foran,Vikas Gupta,Gary J. Schiller,Don Ambrose Stevens,Moshe Talpaz,Sarah Wall,Terra L. Lasho,Abhishek A. Mangaonkar,Talha Badar,Ross Lindsay,Antonio Galleu,Ira Gupta,Naveen Pemmaraju,Guillermo Garcia-Manero
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Minimal residual disease measurement in blood by mass spectrometry identifies long-term responders in multiple myeloma
Clinical Trials & Observations
Tadeusz Kubicki,Benjamin A. Derman,Jennifer H. Cooperrider,Anna Puła,David Barnidge,Dominik Dytfeld,Ken Jiang,Andrzej J. Jakubowiak
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A phase 1 study of IO-202, an anti-LILRB4 antibody, in chronic myelomonocytic leukemia and acute myeloid leukemia
Clinical Trials & Observations
Ahmed Aribi,Gabriel N. Mannis,Yazan F. Madanat,Brian A. Jonas,Neil Dunavin,Gail J. Roboz,Deepa Jeyakumar,Guillermo Garcia-Manero,Hongtao Liu,Hetty E. Carraway,Jennifer N. Saultz,William Blum,Gary Schiller,Tao Huang,Paul Woodard,Barbara Klencke,X. Charlene Liao,Hong Xiang,Daniel A. Pollyea,Courtney D. DiNardo
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MYELOID NEOPLASIA

Targeting scavenger receptor class B type 1 with a bioinspired ligand induces apoptosis or ferroptosis in AML
Adam Y. Lin,Jonathan S. Rink,Eva Yang,Sara Small,Jessica J. Gerber,Taylor J. Zak,Jessica Altman,Yasmin Abaza,Leonidas C. Platanias,Leo I. Gordon,C. Shad Thaxton
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V-FAST: a phase 1b master trial to investigate CPX-351 combined with targeted agents in adults with newly diagnosed AML
Vinod A. Pullarkat,Mark Levis,James McCloskey,Gabriel N. Mannis,Stephen A. Strickland,Amir T. Fathi,Tara L. Lin,Vijaya R. Bhatt,Thuva Vanniyasingam,Divya Chakravarthy,Yana Lutska,Stefan Faderl,Ronald S. Cheung,Harry P. Erba
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Intensive chemotherapy vs venetoclax/hypomethylating agents for patients aged 60 to 75 years with favorable, NPM1-mutated AML
Andrew D Zale,Venkata Preetam Sandeep Kaduluri,Jonathan A Webster,Mark J Levis,Ivana Gojo,Amy E DeZern,Gabriel Ghiaur,Lukasz P Gondek,William Brian Dalton,Theodoros Karantanos,Tania Jain,Gabrielle T Prince,Richard J Jones,B. Douglas Smith,Alexander J Ambinder
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Juvenile myelomonocytic leukemia stem cells are sensitive to NK cell–mediated lysis and express targetable antigens
Shannalee Martinez,Vladimir V. Senyukov,Suheyla Hasgur,Arianexys Aquino-López,Peter D. Emanuel,Y. Lucy Liu,Elliot Stieglitz,Gregory Behbehani,Amanda R. Campbell,Dean A. Lee
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Omacetaxine and venetoclax in relapsed/refractory acute myeloid leukemia or myelodysplastic syndrome with mutant RUNX1
Courtney D. DiNardo,Wei-Ying Jen,Guillermo Montalban-Bravo,Xuemei Wang,Sanam Loghavi,Sravanthi Lavu,Nicholas J. Short,Kelly Chien,Ghayas C. Issa,Naveen Pemmaraju,Musa Yilmaz,Michael Andreeff,Gautam Borthakur,Tapan M. Kadia,Naval G. Daver,Guillermo Garcia-Manero,Christopher P. Mill,Xiaoping Su,Warren Fiskus,Kapil N. Bhalla
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RESEARCH LETTER

Posttranscriptional activity of eIF4E contributes to HoxA9-driven leukemogenesis
Fang Zhou,Biljana Culjkovic-Kraljacic,Christian Bach,Li Feng,Yuta Mishima,Katherine L. B. Borden,Daniel G. Tenen
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Do all patients with chronic phase CML require a diagnostic bone marrow biopsy in the modern TKI era?
Noel F. T. Fong,David M. Ross,David T. Yeung,Timothy P. Hughes,Naranie Shanmuganathan
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Deferring treatment in hairy cell leukemia: is active surveillance safe?
Victoria M. Rogness,Xuefei Jia,Wei Wei,Brian T. Hill
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Three-year follow-up of low-dose, early-start gilteritinib maintenance in posttransplant patients with R/R FLT3mut AML
Clinical Trials & Observations
Toshiki Terao,Ken-ichi Matsuoka,Takumi Kondo,Yoshinobu Maeda
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SRSF2 mutations in CCUS, MDS and AML: a cross-entity study
Sandra Huber,Sarah Ochmann,Stephan Hutter,Veronika Ecker,Manja Meggendorfer,Gregor Hoermann,Torsten Haferlach,Claudia Haferlach,Isolde Summerer
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Lymphoid Neoplasia

Targeting CDK9 inhibits the growth of KMT2A-rearranged infant leukemia and demonstrates synergy with menin inhibition
Ritul Sharma,Chunfen Zhang,Ravi Shah,Melanie M. Frigault,Amy J. Johnson,David Spencer Mangum,Luke D. Maese,Norman J. Lacayo,Aru Narendran
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