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Journal Articles

Inhibition of WNT signaling in the bone marrow niche prevents the development of MDS in the Apc del/ + MDS mouse model

Angela Stoddart, Jianghong Wang, Chunmei Hu, Anthony A. Fernald, Elizabeth M. Davis, Jason X. Cheng, Michelle M. Le Beau
Journal: Blood
Blood (2017) 129 (22): 2959–2970.
https://doi.org/10.1182/blood-2016-08-736454
Published: 2017
Includes: Supplemental data
Journal Articles

Inhibition of Canonical WNT Signaling in the Bone Marrow Niche Prevents the Development of Disease in a Mouse MDS Model with Apc Haploinsufficiency

Angela Stoddart, PhD, Jianghong Wang, MD, Chunmei Hu, MD, Anthony A. Fernald, BS, Elizabeth M. Davis, BS, Jason X. Cheng, MDPhD, Michelle M. Le Beau, PhD
Journal: Blood
Blood (2016) 128 (22): 1129.
https://doi.org/10.1182/blood.V128.22.1129.1129
Published: 2016
Journal Articles

Cytotoxic Exposure to Both Hematopoietic Stem and Progenitor Cells and the Bone Marrow Niche Cooperate to Promote Leukemogenesis in a Mouse Model of Therapy-Related Myeloid Neoplasms with a Del(5q)

Angela Stoddart, PhD, Jianghong Wang, MD, Chunmei Hu, MD, Anthony A. Fernald, BS, Elizabeth M. Davis, BS, Jason X. Cheng, MDPhD, Michelle M. Le Beau, PhD
Journal: Blood
Blood (2015) 126 (23): 357.
https://doi.org/10.1182/blood.V126.23.357.357
Published: 2015
Journal Articles

Haploinsufficiency of del(5q) genes, Egr1 and Apc , cooperate with Tp53 loss to induce acute myeloid leukemia in mice

Angela Stoddart, Anthony A. Fernald, Jianghong Wang, Elizabeth M. Davis, Theodore Karrison, John Anastasi, Michelle M. Le Beau
Journal: Blood
Blood (2014) 123 (7): 1069–1078.
https://doi.org/10.1182/blood-2013-07-517953
Published: 2014
Includes: Supplemental data
Journal Articles

Cell intrinsic and extrinsic factors synergize in mice with haploinsufficiency for Tp53, and two human del(5q) genes, Egr1 and Apc

Angela Stoddart, Jianghong Wang, Anthony A. Fernald, Theodore Karrison, John Anastasi, Michelle M. Le Beau
Journal: Blood
Blood (2014) 123 (2): 228–238.
https://doi.org/10.1182/blood-2013-05-506568
Published: 2014
Includes: Supplemental data
Journal Articles

Haploinsufficiency of Apc leads to ineffective hematopoiesis

Jianghong Wang, Anthony A. Fernald, John Anastasi, Michelle M. Le Beau, Zhijian Qian
Journal: Blood
Blood (2010) 115 (17): 3481–3488.
https://doi.org/10.1182/blood-2009-11-251835
Published: 2010
Includes: Supplemental data
Journal Articles

Expression of Alternative CALM-AF10 Fusions Causes Different Hematological Malignancies in Mice.

Angela Stoddart, PhD, Anthony A. Fernald, B.Sc., Thelma R. Tennant, Ph.D., Elizabeth M. Davis, B.Sc., John Anastasi, M.D., Michelle M. Le Beau, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 2640.
https://doi.org/10.1182/blood.V110.11.2640.2640
Published: 2007
Journal Articles

Haploinsufficiency of EGR1 , a candidate gene in the del(5q), leads to the development of myeloid disorders

John M. Joslin, Anthony A. Fernald, Thelma R. Tennant, Elizabeth M. Davis, Scott C. Kogan, John Anastasi, John D. Crispino, Michelle M. Le Beau
Journal: Blood
Blood (2007) 110 (2): 719–726.
https://doi.org/10.1182/blood-2007-01-068809
Published: 2007
Includes: Supplemental data
Journal Articles

Egr1, a Candidate Gene within the Commonly Deleted Segment of Chromosome 5, Plays a Role in Murine Erythropoiesis and Leukemogenesis.

John M. Joslin, BS, Anthony A. Fernald, BS, Zhijian Qian, PhD, John D. Crispino, PhD, Michelle M. Le Beau, PhD
Journal: Blood
Blood (2005) 106 (11): 663.
https://doi.org/10.1182/blood.V106.11.663.663
Published: 2005
Journal Articles

Fluorescence in situ hybridization: a sensitive method for trisomy 8 detection in bone marrow specimens

RB Jenkins, MM Le Beau, WJ Kraker, TJ Borell, PG Stalboerger, EM Davis, L Penland, A Fernald, R 3d Espinosa, DJ Schaid
Journal: Blood
Blood (1992) 79 (12): 3307–3315.
https://doi.org/10.1182/blood.V79.12.3307.3307
Published: 1992