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Journal Articles

Mitochondrial Dysfunction in Normal and Malignant Hematopoiesis

Aaron Schimmer, MD PhD

Blood (2018) 132 (Supplement 1): SCI-11.

https://doi.org/10.1182/blood-2018-99-109470

Published: 2018

Journal Articles

The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Supercomplex Formation and Represents a New Therapeutic Target for AML

Sara Mirali, Botham Aaron, Veronique Voisin, PhD, Yihua Qiu, Fieke W Hoff, BSc, Rose Hurren, BSc, Marcela Gronda, MSc, Yulia Jitkova, PhD, G. Wei Xu, Neil MacLean, Xiaoming Wang, Terzah M. Horton, MD PhD, Steven M. Kornblau, MD, Steven M Chan, MD PhD, Gary D Bader, Aaron Schimmer, MD PhD

Blood (2018) 132 (Supplement 1): 1335.

https://doi.org/10.1182/blood-2018-99-110869

Published: 2018

Journal Articles

Targeting the Mitochondrial Metallochaperone Cox17 Reduces DNA Methylation and Promotes AML Differentiation through a Copper Dependent Mechanism

Blood (2018) 132 (Supplement 1): 1339.

https://doi.org/10.1182/blood-2018-99-111015

Published: 2018

Journal Articles

Migration in the Management of Philadelphia Positive ALL: Towards a Lower Risk of VTE

Hassan Sibai, MBBS, Maria Zigas, Arjun Datt Law, MBBS, MD DM, Umberto Falcone, MD, Solaf Sami Kanfar, MD, Naoko Sakurai, Vikas Gupta, MD PhD, Andre Schuh, MD FRCPC, Karen W.L. Yee, MD, Aaron Schimmer, MD PhD, Mark D. Minden, MD PhD, Dawn Maze, MD FRCPC, MSc, Steven M. Chan, MDPhD, Jack Seki, PharmD

Blood (2017) 130 (Supplement 1): 1283.

https://doi.org/10.1182/blood.V130.Suppl_1.1283.1283

Published: 2017

Journal Articles

Tafazzin (TAZ) Regulates the Differentiation of AML Cells By Reducing Levels of the Phospholipid Phosphatidylethanolamine

Blood (2017) 130 (Supplement 1): 788.

https://doi.org/10.1182/blood.V130.Suppl_1.788.788

Published: 2017

Journal Articles

The Utility of Early Broncholaveolar Lavage in Prolonged Neutropenic Patients with Pulmonary Nodules

Dina Khalaf, MD BSc, Steven M. Chan, MD PhD, Vikas Gupta, MD PhD, Andrzej Lutynski, MD, Dawn Maze, MD FRCPC, MSc, Mark D. Minden, MD PhD, Yoichiro Natori, MD, Rhea Pavan, BA, Amr Rostom, MD, Anna Rydlewski, MD, Aaron Schimmer, MD PhD, Andre Schuh, MD FRCPC, Hassan Sibai, MBBS, Karen W.L. Yee, MD, Shahid Husain, MD MS

Blood (2017) 130 (Supplement 1): 4682.

https://doi.org/10.1182/blood.V130.Suppl_1.4682.4682

Published: 2017

Journal Articles

Azacitidine Has Limited Activity in Patients with MDS and AML

Karen Yee, MD, Symron Bansal, Joseph Brandwein, MD, Mark D. Minden, MD, Aaron Schimmer, MD, PhD, Vikas Gupta, MD, FRCP, FRCPath, Arsenia Dharman, Christine Cserti-Gazdewich, MD, Andre Schuh, MD, FRCPC

Blood (2011) 118 (21): 5057.

https://doi.org/10.1182/blood.V118.21.5057.5057

Published: 2011

Journal Articles

A Phase I Study of ENMD-2076 In Patients with Relapsed or Refractory Leukemia

Karen W.L. Yee, MD, Hsaio-Wei Tina Chen, Joseph Brandwein, MD, FRCPC, Sue Chow, Deborah Sanfelice, David Hedley, MD, Vikas Gupta, MD, MRCP, FRCPath, Aaron Schimmer, MD, PhD, Carolyn Fowler Sidor, MD, Graham Fletcher, Jamie Arnott, Mark Bray, Mark D. Minden, MD, PhD, Andre Schuh, MD, FRCPC

Blood (2010) 116 (21): 3307.

https://doi.org/10.1182/blood.V116.21.3307.3307

Published: 2010

Journal Articles

Clioquinol Arrests Cell Cycle at G1 Phase and Triggers Intrinsic Apoptosis In Myeloma and Leukemia Cells by Inhibiting Histone Deacetylases

Biyin Cao, Tingjun Hou, PhD, Suning Chen, Depei Wu, Aining Sun, Huiying Qiu, Wenjie Wang, Aaron Schimmer, MD, PhD, Xinliang Mao, MD, PhD

Blood (2010) 116 (21): 1836.

https://doi.org/10.1182/blood.V116.21.1836.1836

Published: 2010

Journal Articles

The Anti-Malarial Mefloquine Demonstrates Preclinical Activity In Leukemia and Myeloma, and Is Dependent Upon Toll-Like Receptor Signaling for Its Cytotoxicity

Mahadeo A. Sukhai, PhD, Xiaoming Li, PhD, Rose Hurren, Xiaoming Wang, Skrtic Marko, B.Sc., Hong Sun, Marcela Gronda, Ayesh Seneviratne, Dilan Dissanayake, Sue Chow, Rod Bremner, PhD, David Hedley, MD, Mark D. Minden, MD, PhD, Ohashi Pamela, PhD, FRSC, Aaron Schimmer, MD, PhD

Blood (2010) 116 (21): 290.

https://doi.org/10.1182/blood.V116.21.290.290

Published: 2010

Journal Articles

A Prognostic Score of Overall Survival In Adults with Acute Myeloid Leukemia

Murtadha K. Al-Khabori, MD, FRCPC, Gordon Guyatt, MD, FRCPC, Mark D. Minden, MD, PhD, Karen Yee, MD, Vikas Gupta, MD, MRCP, FRCPath, Aaron Schimmer, MD, PhD, Andre Schuh, MD, FRCPC, Joseph Brandwein, MD, FRCPC

Blood (2010) 116 (21): 2730.

https://doi.org/10.1182/blood.V116.21.2730.2730

Published: 2010

Journal Articles

Validation of Monosomal Karyotype Based Model In the Risk Stratification of Acute Myeloid Leukemia

Murtadha K. Al-Khabori, MD, FRCPC, Karen Yee, MD, Vikas Gupta, MD, MRCP, FRCPath, Aaron Schimmer, MD, PhD, Andre Schuh, MD, FRCPC, Mark D. Minden, MD, PhD, Joseph Brandwein, MD, FRCPC

Blood (2010) 116 (21): 2745.

https://doi.org/10.1182/blood.V116.21.2745.2745

Published: 2010

Journal Articles

A Phase I Trial of Two Sequence-Specific Schedules of Decitabine and Vorinostat in Patients with Acute Myeloid Leukemia (AML).

Karen W.L. Yee, MD, Mark D. Minden, MD, Joseph Brandwein, MD, Aaron Schimmer, MD, Andre Schuh, MD, Vikas Gupta, MD, Hans A. Messner, MD, Ronan Foley, MD, Parveen Wasi, MD, James A. Zwiebel, MD, Brian Leber, MD

Blood (2007) 110 (11): 908.

https://doi.org/10.1182/blood.V110.11.908.908

Published: 2007

Journal Articles

Treatment of Adult Acute Lymphoblastic Leukemia (ALL) with a Modified DFCI Pediatric Regimen - The Princess Margaret Experience.

John M. Storring, MDCM, Joseph Brandwein, MD, Vikas Gupta, MD, Andre C. Schuh, MD, Aaron Schimmer, MD PhD, Karen Yee, MD, Richard A. Wells, MD DPhil, Jeffrey H. Lipton, MD PhD, Hans A. Messner, MD PhD, Wei Xu, MSc, Mark D. Minden, MD PhD

Blood (2006) 108 (11): 1875.

https://doi.org/10.1182/blood.V108.11.1875.1875

Published: 2006

Journal Articles

Chemical Library Screening Identifies Novel Inhibitors of Cyclin D2 ( CCND2) Transactivation That Selectively Induce Apoptosis in Multiple Myeloma Cells.

Rodger E. Tiedemann, MD, PhD, Xinliang Mao, PhD, Chng-Xin Shi, PhD, Yuan Xiao Zhang, PhD, Stephen Palmer, Craig B. Reeder, MD, Aaron Schimmer, MD, Keith Stewart, MD

Blood (2006) 108 (11): 3421.

https://doi.org/10.1182/blood.V108.11.3421.3421

Published: 2006

Journal Articles

Kinetin Riboside Is a Novel Targeted Inhibitor of CCND1 and CCND2 Transactivation with Substantial Preclinical Anti-Myeloma Activity.

Rodger E. Tiedemann, MD, PhD, Xinliang Mao, PhD, Ronald J. Marler, DVM, PhD, Craig B. Reeder, MD, Aaron Schimmer, MD, Keith Stewart, MD

Blood (2006) 108 (11): 367.

https://doi.org/10.1182/blood.V108.11.367.367

Published: 2006

Journal Articles

Silencing of Caspase 8 Expression in Leukemia Cells and Patient Samples.

Patricia Disperati, MD, Fernando Suarez-Saiz, MD, Marcela Gronda, MSc, Mark D. Minden, MD, PhD, Aaron Schimmer, MD, PhD

Blood (2004) 104 (11): 2050.

https://doi.org/10.1182/blood.V104.11.2050.2050

Published: 2004

NARROW

Mitochondrial Dysfunction in Normal and Malignant Hematopoiesis

The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Supercomplex Formation and Represents a New Therapeutic Target for AML

Targeting the Mitochondrial Metallochaperone Cox17 Reduces DNA Methylation and Promotes AML Differentiation through a Copper Dependent Mechanism

Migration in the Management of Philadelphia Positive ALL: Towards a Lower Risk of VTE

Tafazzin (TAZ) Regulates the Differentiation of AML Cells By Reducing Levels of the Phospholipid Phosphatidylethanolamine

The Utility of Early Broncholaveolar Lavage in Prolonged Neutropenic Patients with Pulmonary Nodules

Azacitidine Has Limited Activity in Patients with MDS and AML

A Phase I Study of ENMD-2076 In Patients with Relapsed or Refractory Leukemia

Clioquinol Arrests Cell Cycle at G1 Phase and Triggers Intrinsic Apoptosis In Myeloma and Leukemia Cells by Inhibiting Histone Deacetylases

The Anti-Malarial Mefloquine Demonstrates Preclinical Activity In Leukemia and Myeloma, and Is Dependent Upon Toll-Like Receptor Signaling for Its Cytotoxicity

A Prognostic Score of Overall Survival In Adults with Acute Myeloid Leukemia

Validation of Monosomal Karyotype Based Model In the Risk Stratification of Acute Myeloid Leukemia

A Phase I Trial of Two Sequence-Specific Schedules of Decitabine and Vorinostat in Patients with Acute Myeloid Leukemia (AML).

Treatment of Adult Acute Lymphoblastic Leukemia (ALL) with a Modified DFCI Pediatric Regimen - The Princess Margaret Experience.

Chemical Library Screening Identifies Novel Inhibitors of Cyclin D2 ( CCND2) Transactivation That Selectively Induce Apoptosis in Multiple Myeloma Cells.

Kinetin Riboside Is a Novel Targeted Inhibitor of CCND1 and CCND2 Transactivation with Substantial Preclinical Anti-Myeloma Activity.

Silencing of Caspase 8 Expression in Leukemia Cells and Patient Samples.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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