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Journal Articles

Improved Survival with Enzastaurin Treatment in Diffuse Large B-Cell Lymphoma Patients with the Novel Genetic Biomarker, DGM1

Wen Luo, PhD, Hong Sun, MS, Jun Zhu, Stephen D. Smith, MD, Isabel Han, BS, Ronald Shazer, MD

Blood (2018) 132 (Supplement 1): 4207.

https://doi.org/10.1182/blood-2018-99-115807

Published: 2018

Journal Articles

Erythrocyte Adenosine A2B Receptor-Mediated AMP-Activated Protein Kinase Prevents Hypoxia-Induced Tissue Injury in High Altitude By Inducing 2,3-Bisphosphoglycerate

Hong Liu, MD, Yujin Zhang, PhD, Anren Song, PhD, Harry Karmouty Quintana, PhD, Almut Grenz, MD PhD, Hong Sun, MD PhD, Rodney E. Kellems, PhD, Holger Eltzschig, PhD, Robert Roach, PhD, Michael R. Blackburn, PhD, Yang Xia, MD PhD

Blood (2014) 124 (21): 2664.

https://doi.org/10.1182/blood.V124.21.2664.2664

Published: 2014

Journal Articles

Frequent Activating Mutations Of JAK-STAT Pathway Genes In Natural Killer Cell Lymphomas

Blood (2013) 122 (21): 812.

https://doi.org/10.1182/blood.V122.21.812.812

Published: 2013

Journal Articles

L-Leucine Improves the Anemia of DBA and the 5q- Syndrome Via Activation of the mTOR Pathway in a p53-Independent Manner

Nirmalee Abayasekara, MS, Anupama Narla, Slater Hurst, BS, Hong Sun, MD, Maria Virgilio, Elspeth Payne, Benjamin L. Ebert, MD, PhD, A. Thomas Look, M.D., Nancy Berliner, MD, Arati Khanna-Gupta, PhD

Blood (2012) 120 (21): 1257.

https://doi.org/10.1182/blood.V120.21.1257.1257

Published: 2012

Journal Articles

L-leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway

Elspeth M. Payne, Maria Virgilio, Anupama Narla, Hong Sun, Michelle Levine, Barry H. Paw, Nancy Berliner, A. Thomas Look, Benjamin L. Ebert, Arati Khanna-Gupta

Blood (2012) 120 (11): 2214–2224.

https://doi.org/10.1182/blood-2011-10-382986

Published: 2012

Includes: Supplemental data

Journal Articles

Upregulation of eIF4E in Nucleophosmin 1 (NPM1) Haploinsufficient Cells Alters CCAAT Enhancer Binding Protein Alpha (C/EBPα) Activity: Implications for MDS and AML

Nirmalee Abayasekara, MS, Michelle Levine, BS, Niccolo Bolli, MD, Hong Sun, MD, Matthew Silver, BS, Navid Nia, Paolo Sportoletti, MD, Pier Paolo Pandolfi, MD, PhD, Nancy Berliner, MD, Arati Khanna-Gupta, PhD

Blood (2011) 118 (21): 2432.

https://doi.org/10.1182/blood.V118.21.2432.2432

Published: 2011

Journal Articles

Discovery of Non-Peptidyl Small-Molecule Human GCSF Receptor Agonists for the Potential Treatment of Neutropenia,

Keith Marschke, PhD, Deepa Rungta, PhD, Daniela A Slavin, PhD, Jennifer Sanders, B.S., Steven L Roach, PhD, Jason C Pickens, PhD, Yixing Shen, Arjan van Oeveren, PhD, Mei Hua Hong, MD, PhD, Hong Sun, Reid P. Bissonnette, PhD, Peter M Syka, Lin Zhi, PhD

Blood (2011) 118 (21): 3391.

https://doi.org/10.1182/blood.V118.21.3391.3391

Published: 2011

Journal Articles

L-Leucine Improves the Anemia of the 5q- Syndrome Via Activation of the mTOR (mammalian target of rapamycin) Pathway

Maria Virgilio, Elspeth Payne, MB, ChB, Ph.D, Anupama Narla, MD, Hong Sun, MD, Barry H. Paw, M.D., Ph.D., Thomas Look, MD, Benjamin L. Ebert, MD, D.Phil, Nancy Berliner, MD, Arati Khanna-Gupta, PhD

Blood (2011) 118 (21): 970.

https://doi.org/10.1182/blood.V118.21.970.970

Published: 2011

Journal Articles

Lysosomal Disruption Selectively Targets Leukemia Cells and Leukemia Stem Cells Through A Mechanism Related to Increased Reactive Oxygen Species Production

Blood (2011) 118 (21): 61.

https://doi.org/10.1182/blood.V118.21.61.61

Published: 2011

Journal Articles

Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML

Elspeth M. Payne, Niccolò Bolli, Jennifer Rhodes, Omar I. Abdel-Wahab, Ross Levine, Cyrus V. Hedvat, Richard Stone, Arati Khanna-Gupta, Hong Sun, John P. Kanki, Hanna T. Gazda, Alan H. Beggs, Finbarr E. Cotter, A. Thomas Look

Blood (2011) 118 (4): 903–915.

https://doi.org/10.1182/blood-2010-11-318022

Published: 2011

Includes: Multimedia, Supplemental data

Journal Articles

The Anti-Malarial Mefloquine Demonstrates Preclinical Activity In Leukemia and Myeloma, and Is Dependent Upon Toll-Like Receptor Signaling for Its Cytotoxicity

Mahadeo A. Sukhai, PhD, Xiaoming Li, PhD, Rose Hurren, Xiaoming Wang, Skrtic Marko, B.Sc., Hong Sun, Marcela Gronda, Ayesh Seneviratne, Dilan Dissanayake, Sue Chow, Rod Bremner, PhD, David Hedley, MD, Mark D. Minden, MD, PhD, Ohashi Pamela, PhD, FRSC, Aaron Schimmer, MD, PhD

Blood (2010) 116 (21): 290.

https://doi.org/10.1182/blood.V116.21.290.290

Published: 2010

Journal Articles

Treatment of Zebrafish Models of Ribosomopathies (Diamond Blackfan Anemia (DBA) and 5q- Syndrome) with L-Leucine Results In An Improvement of Anemia and Developmental Defects: Evidence for a Common Pathway?

Maria Virgilio, Elspeth Payne, MBChB, Anupama Narla, MD, Hong Sun, MD, Barry Paw, M.D., Ph.D., A. Thomas Look, MD, Benjamin L. Ebert, MD, DPhil, Nancy Berliner, MD, Arati Khanna-Gupta, PhD

Blood (2010) 116 (21): 195.

https://doi.org/10.1182/blood.V116.21.195.195

Published: 2010

Journal Articles

5-Azacytidine to Treat Acute Myeloid Leukemia In Elderly or Frail Patients: A Phase II Study (SAKK 30/07)

Jakob R. Passweg, MD, MS, Thomas Pabst, Sabine Blum, Mario Bargetzi, Hong Sun, Dominik Heim, MD, Georg Stussi, MD, Michael Gregor, Leda Leoncini, Sandrine Meyer-Monard, MD, Peter Brauchli, Yves Chalandon, MD

Blood (2010) 116 (21): 2181.

https://doi.org/10.1182/blood.V116.21.2181.2181

Published: 2010

Journal Articles

NON-Peptidyl Small Molecule EPO Receptor Agonists Are Potent Pathway Selective Inducers of Erythropoiesis.

Reid P. Bissonnette, PhD, Deepa Rungta, PhD, Andrew R Hudson, PhD, Steven L Roach, PhD, Mei Hua Hong, MD, PhD, Hong Sun, Junlian Hu, James N Ward, Wen Luo, PhD, Jen E Sanders, Peter M Syka, Daniela A Slavin, PhD, Lin Zhi, PhD, Keith B Marschke, PhD

Blood (2010) 116 (21): 1565.

https://doi.org/10.1182/blood.V116.21.1565.1565

Published: 2010

Journal Articles

Understanding the Impact of Inflammation on Hematopoietic Stem Cells.

Ying Zhao, Flora Ling, Hong-Cheng Wang, Xiao-Hong Sun, PhD

Blood (2010) 116 (21): 2629.

https://doi.org/10.1182/blood.V116.21.2629.2629

Published: 2010

Journal Articles

The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells

Sumaiya Sharmeen, Marko Skrtic, Mahadeo A. Sukhai, Rose Hurren, Marcela Gronda, Xiaoming Wang, Sonali B. Fonseca, Hong Sun, Tabitha E. Wood, Richard Ward, Mark D. Minden, Robert A. Batey, Alessandro Datti, Jeff Wrana, Shana O. Kelley, Aaron D. Schimmer

Blood (2010) 116 (18): 3593–3603.

https://doi.org/10.1182/blood-2010-01-262675

Published: 2010

Includes: Supplemental data

Journal Articles

Both p53-Dependent and -Independent Pathways Contribute to Erythroid Dysplasia in a Zebrafish Model for Diamond Blackfan Anemia.

Elspeth Payne, MBChB, BSc, MRCP, Hong Sun, Barry H. Paw, M.D., Ph.D., A. Thomas Look, MD, Arati Khanna-Gupta, PhD

Blood (2009) 114 (22): 177.

https://doi.org/10.1182/blood.V114.22.177.177

Published: 2009

Journal Articles

Nucleophosmin-1 Interacts with CCAAT Enhancer Binding Protein Alpha (C/EBPα) to Facilitate Granulocyte Maturation: Implications in MDS and AML.

Arati Khanna-Gupta, PhD, Jian Chen, Matthew Silver, BS, Hong Sun, Nirmalee Abayasekara, MS, Stephanie Halene, MD, Paolo Sportoletti, MD, Pier Paolo Pandolfi, MD, PhD, Nancy Berliner, MD

Blood (2009) 114 (22): 2768.

https://doi.org/10.1182/blood.V114.22.2768.2768

Published: 2009

Journal Articles

The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development

Nicola K. Wilson, Diego Miranda-Saavedra, Sarah Kinston, Nicolas Bonadies, Samuel D. Foster, Fernando Calero-Nieto, Mark A. Dawson, Ian J. Donaldson, Stephanie Dumon, Jonathan Frampton, Rekin's Janky, Xiao-Hong Sun, Sarah A. Teichmann, Andrew J. Bannister, Berthold Göttgens

Blood (2009) 113 (22): 5456–5465.

https://doi.org/10.1182/blood-2009-01-200048

Published: 2009

Includes: Supplemental data

Journal Articles

Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus–prone B6. Sle1.Yaa animals

Kenichiro Maeda, Alex Malykhin, Brittany N. Teague-Weber, Xiao-Hong Sun, A. Darise Farris, K. Mark Coggeshall

Blood (2009) 113 (19): 4534–4540.

https://doi.org/10.1182/blood-2008-12-192559

Published: 2009

NARROW

Improved Survival with Enzastaurin Treatment in Diffuse Large B-Cell Lymphoma Patients with the Novel Genetic Biomarker, DGM1

Erythrocyte Adenosine A2B Receptor-Mediated AMP-Activated Protein Kinase Prevents Hypoxia-Induced Tissue Injury in High Altitude By Inducing 2,3-Bisphosphoglycerate

Frequent Activating Mutations Of JAK-STAT Pathway Genes In Natural Killer Cell Lymphomas

L-Leucine Improves the Anemia of DBA and the 5q- Syndrome Via Activation of the mTOR Pathway in a p53-Independent Manner

L-leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway

Upregulation of eIF4E in Nucleophosmin 1 (NPM1) Haploinsufficient Cells Alters CCAAT Enhancer Binding Protein Alpha (C/EBPα) Activity: Implications for MDS and AML

Discovery of Non-Peptidyl Small-Molecule Human GCSF Receptor Agonists for the Potential Treatment of Neutropenia,

L-Leucine Improves the Anemia of the 5q- Syndrome Via Activation of the mTOR (mammalian target of rapamycin) Pathway

Lysosomal Disruption Selectively Targets Leukemia Cells and Leukemia Stem Cells Through A Mechanism Related to Increased Reactive Oxygen Species Production

Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML

The Anti-Malarial Mefloquine Demonstrates Preclinical Activity In Leukemia and Myeloma, and Is Dependent Upon Toll-Like Receptor Signaling for Its Cytotoxicity

Treatment of Zebrafish Models of Ribosomopathies (Diamond Blackfan Anemia (DBA) and 5q- Syndrome) with L-Leucine Results In An Improvement of Anemia and Developmental Defects: Evidence for a Common Pathway?

5-Azacytidine to Treat Acute Myeloid Leukemia In Elderly or Frail Patients: A Phase II Study (SAKK 30/07)

NON-Peptidyl Small Molecule EPO Receptor Agonists Are Potent Pathway Selective Inducers of Erythropoiesis.

Understanding the Impact of Inflammation on Hematopoietic Stem Cells.

The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells

Both p53-Dependent and -Independent Pathways Contribute to Erythroid Dysplasia in a Zebrafish Model for Diamond Blackfan Anemia.

Nucleophosmin-1 Interacts with CCAAT Enhancer Binding Protein Alpha (C/EBPα) to Facilitate Granulocyte Maturation: Implications in MDS and AML.

The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development

Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus–prone B6. Sle1.Yaa animals

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American Society of Hematology

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American Society of Hematology

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