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Journal Articles

Human CMVpp65-Specific Stem Cell-like Memory T-Cells (T SCM ) Are a Principal Source for Rapid Repopulation of Immunodominant Central Memory (T CM ) and Effector Memory (T EM ) in the Circulation

Tzu-Yun Kuo, Aisha Hasan, MD, Manuel Guerreiro, MD, Richard J. O'Reilly, MD

Blood (2016) 128 (22): 5728.

https://doi.org/10.1182/blood.V128.22.5728.5728

Published: 2016

Journal Articles

Successful Treatment of Refractory CMV Chorioretinitis and Meningoencephalitis with Adoptive Transfer of Third Party CMVpp65 Specific T-Cell Lines

Susan Prockop, MD, Aisha Hasan, MD, Ekaterina Doubrovina, MD PhD, H.R. Castro-Malaspina, MD, Juliet N. Barker, MBBS(Hons), FRACP, Parastoo B Dahi, MD, Farid Boulad, MD, Nancy A. Kernan, MD, Guenther Koehne, MD PhD, Craig S. Sauter, MD, Szilard Kiss, MD, Mrinali Patel, MD, Stephanie Suser, BA, Richard J O'Reilly, MD

Blood (2015) 126 (23): 3157.

https://doi.org/10.1182/blood.V126.23.3157.3157

Published: 2015

Journal Articles

A Comparison of Human CMVpp65-Specific Central Memory and Effector Memory CD8 T-Cells When Stimulated in-Vivo with IL-2 or IL-15/IL-15Rα Complex in a Murine Xenograft Model of Adoptive Cell Therapy

Tzu-Yun Kuo, Aisha Hasan, MD, Richard J O'Reilly, MD

Blood (2014) 124 (21): 4805.

https://doi.org/10.1182/blood.V124.21.4805.4805

Published: 2014

Journal Articles

Third Party Donor Derived CMV Specific T Cells for the Treatment of Refractory CMV Viremia and Disease after Hematopoietic Stem Cell Transplant

Susan E. Prockop, MD, Aisha Hasan, MD, Guenther Koehne, MD PhD, Ekaterina Doubrovina, MD PhD, Craig S. Sauter, MD, Juliet N, Barker, MBBS, Karim Baroudy, Farid Boulad, MD, Sergio Giralt, MD, Ramzi Khalaf, Nancy A. Kernan, MD, Esperanza B Papadopoulos, MD, Doris M. Ponce, MD, Andromachi Scaradavou, MD, Stephanie Suser, Gloria Wasilewski, RN, Richard J. O'Reilly, MD

Blood (2014) 124 (21): 184.

https://doi.org/10.1182/blood.V124.21.184.184

Published: 2014

Journal Articles

Myeloablative Double-Unit Cord Blood Transplantation (CBT) in Pediatric Patients with High-Risk Acute Leukemia Demonstrates Encouraging Disease-Free Survival with Both TBI and Chemotherapy-Only-Based Conditioning

Andromachi Scaradavou, MD, Marissa N Lubin, BA, Patrick Hilden, MS, Farid Boulad, MD, Kevin J. Curran, MD, Rachel Kobos, MD, Susan E. Prockop, MD, Richard J. O'Reilly, MD, Jo-Ann Tonon, Courtney Byam, BS, Peter G Steinherz, MD, Neerav Shukla, MD, Aisha Hasan, MD, Thomas M. Renaud, MD, Nicole Zakak, N.P., Nancy A. Kernan, MD, Juliet N. Barker, MBBS(Hons), FRACP

Blood (2014) 124 (21): 2578.

https://doi.org/10.1182/blood.V124.21.2578.2578

Published: 2014

Journal Articles

CMV-Specific T-Cells Are More Effective Than WT-1-Specific T-Cells in Eradicating Clonogenic Tumor Cells Co-Expressing CMVpp65 and WT-1 in-Vivo and Both Types of T-Cells Are Functionally Augmented in the Presence of IL-15/IL-15Rα

Aisha Hasan, MD, Dana Bakalar, B.S, Annamalai Selvakumar, PhD, Gloria C Koo, PhD, Ekaterina Doubrovina, MD, PhD, Tzu-Yun Kuo, M.S, Richard J. O'Reilly, MD

Blood (2011) 118 (21): 646.

https://doi.org/10.1182/blood.V118.21.646.646

Published: 2011

Journal Articles

The Capacity of CMV-Specific T-Cells to Prevent Outgrowth of Clonogenic Human Colon Carcinoma Cells Co-Expressing CMVpp65 in-Vivo and Durably Suppress Established CMVpp65 + Tumor Xenografts Is Dose Dependant and Can Be Augmented by IL-15/IL-15Rα

Aisha Hasan, MD, Annamalai Selvakumar, PhD, Gloria C Koo, PhD, Dana Bakalar, B.S, Richard J. O’Reilly, MD

Blood (2011) 118 (21): 4307.

https://doi.org/10.1182/blood.V118.21.4307.4307

Published: 2011

Journal Articles

Rituximab Maintenance Treatment In Immune Mediated Thrombocytopenia (ITP) Including Evans Syndrome

Michelle Mahler, MD, Aisha Hasan, MD, James B. Bussel, MD

Blood (2010) 116 (21): 2523.

https://doi.org/10.1182/blood.V116.21.2523.2523

Published: 2010

Journal Articles

A Phase I Dose Escalation Trial of Donor T Cells Sensitized with Pentadecapeptides of the CMV-pp65 Protein for the Treatment of CMV Infections Following Allogeneic Hematopoietic Stem Cell Transplants.

Guenther Koehne, MD, PhD, Ekaterina Doubrovina, MD, PhD, Aisha Hasan, MD, Juliet Barker, MBBS, H.R. Castro-Malaspina, MD, Miguel Perales, MD, Ann Jakubowski, PhD, MD, Esperanza B Papadopoulos, MD, James W. Young, MD, Farid Boulad, MD, Trudy N Small, MD, Susan E Prockop, MD, Nancy A. Kernan, MD, Andromachi Scaradavou, MD, Genovefa Papanicolaou, Marcel van den Brink, MD, PhD, Richard J O'Reilly, MD

Blood (2009) 114 (22): 2262.

https://doi.org/10.1182/blood.V114.22.2262.2262

Published: 2009

Journal Articles

Generation of T Cells of Desired HLA Restriction Specific for Epitopes of a Self-Antigen, WT1, for the Adoptive Immunotherapy of WT1 Positive Malignancies Using A Panel of Artificial Antigen Presenting Cells Expressing Prevalent HLA Alleles.

Ekaterina Doubrovina, MD, PhD, Aisha Hasan, MD, Banu Oflaz-Sozmen, MD, Annamalai Selvakumar, Michel W Sadelain, MD, PhD, Richard J O'Reilly, MD

Blood (2009) 114 (22): 4086.

https://doi.org/10.1182/blood.V114.22.4086.4086

Published: 2009

Journal Articles

Quantitation of WT1 Transcripts by Copy Number Provides a Sensitive Indication of Minimal Residual Disease (MRD) and Response to Adoptive Cell Therapy in Patients Transplanted for Ph(+) CML.

Annamalai Selvakumar, PhD, Aisha Hasan, MD, Vidhi Desai, MS, Gianfranco Pittari, MD, Lorna Barnett, BS, Esperanza B Papadopoulos, MD, Richard J O'Reilly, MD

Blood (2009) 114 (22): 4489.

https://doi.org/10.1182/blood.V114.22.4489.4489

Published: 2009

Journal Articles

Adoptive Immunotherapy for CMV Infection Complicating Haploidentical Transplants: Challenges Posed by the HLA Restriction of Immuno- Dominant Donor T Cells

Aisha Hasan, MD, Ekatarina Doubrovina, MD, Deepa Trivedi, M.B.B.S., Nancy A. Kernan, MD, Susan Prockop, MD, Richard J. O’Reilly

Blood (2008) 112 (11): 2918.

https://doi.org/10.1182/blood.V112.11.2918.2918

Published: 2008

Journal Articles

IL-15 Augments in-Vitro Expansion and Functional Activity of Antigen-Specific Effector Memory T-Cells (T EM ) While Co-Expression of IL-15 and IL-15 Rα on Antigen Presenting Cells Also Promotes Expansion of Central Memory T-Cells (T CM )

Aisha Hasan, MD, Annamalai Selvakumar, PhD, Bo Dupont, MD, DSc, Michel Sadelain, MD, Isabelle Riviere, PhD, Richard J O’Reilly, MD

Blood (2008) 112 (11): 3541.

https://doi.org/10.1182/blood.V112.11.3541.3541

Published: 2008

Journal Articles

A Panel of Artificial Antigen-Presenting Cells (AAPC) Expressing Prevalent HLA Alleles Permits Generation of Cytotoxic T Cells Specific for Both Subdominant and Dominant Viral Epitopes for Adoptive Therapy.

Aisha Hasan, MD, Wouter J. Kollen, MD, PhD, A. Selvakumar, PhD, D. Trivedi, MD, M. Sadelain, MD, Richard J. O’Reilly

Blood (2007) 110 (11): 2589.

https://doi.org/10.1182/blood.V110.11.2589.2589

Published: 2007

NARROW

Human CMVpp65-Specific Stem Cell-like Memory T-Cells (T SCM ) Are a Principal Source for Rapid Repopulation of Immunodominant Central Memory (T CM ) and Effector Memory (T EM ) in the Circulation

Successful Treatment of Refractory CMV Chorioretinitis and Meningoencephalitis with Adoptive Transfer of Third Party CMVpp65 Specific T-Cell Lines

A Comparison of Human CMVpp65-Specific Central Memory and Effector Memory CD8 T-Cells When Stimulated in-Vivo with IL-2 or IL-15/IL-15Rα Complex in a Murine Xenograft Model of Adoptive Cell Therapy

Third Party Donor Derived CMV Specific T Cells for the Treatment of Refractory CMV Viremia and Disease after Hematopoietic Stem Cell Transplant

Myeloablative Double-Unit Cord Blood Transplantation (CBT) in Pediatric Patients with High-Risk Acute Leukemia Demonstrates Encouraging Disease-Free Survival with Both TBI and Chemotherapy-Only-Based Conditioning

CMV-Specific T-Cells Are More Effective Than WT-1-Specific T-Cells in Eradicating Clonogenic Tumor Cells Co-Expressing CMVpp65 and WT-1 in-Vivo and Both Types of T-Cells Are Functionally Augmented in the Presence of IL-15/IL-15Rα

The Capacity of CMV-Specific T-Cells to Prevent Outgrowth of Clonogenic Human Colon Carcinoma Cells Co-Expressing CMVpp65 in-Vivo and Durably Suppress Established CMVpp65 + Tumor Xenografts Is Dose Dependant and Can Be Augmented by IL-15/IL-15Rα

Rituximab Maintenance Treatment In Immune Mediated Thrombocytopenia (ITP) Including Evans Syndrome

A Phase I Dose Escalation Trial of Donor T Cells Sensitized with Pentadecapeptides of the CMV-pp65 Protein for the Treatment of CMV Infections Following Allogeneic Hematopoietic Stem Cell Transplants.

Generation of T Cells of Desired HLA Restriction Specific for Epitopes of a Self-Antigen, WT1, for the Adoptive Immunotherapy of WT1 Positive Malignancies Using A Panel of Artificial Antigen Presenting Cells Expressing Prevalent HLA Alleles.

Quantitation of WT1 Transcripts by Copy Number Provides a Sensitive Indication of Minimal Residual Disease (MRD) and Response to Adoptive Cell Therapy in Patients Transplanted for Ph(+) CML.

Adoptive Immunotherapy for CMV Infection Complicating Haploidentical Transplants: Challenges Posed by the HLA Restriction of Immuno- Dominant Donor T Cells

IL-15 Augments in-Vitro Expansion and Functional Activity of Antigen-Specific Effector Memory T-Cells (T EM ) While Co-Expression of IL-15 and IL-15 Rα on Antigen Presenting Cells Also Promotes Expansion of Central Memory T-Cells (T CM )

A Panel of Artificial Antigen-Presenting Cells (AAPC) Expressing Prevalent HLA Alleles Permits Generation of Cytotoxic T Cells Specific for Both Subdominant and Dominant Viral Epitopes for Adoptive Therapy.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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