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Journal Articles

TCR Repertoires in Graft-Versus-Host-Disease (GVHD)-Target Tissues Reveals Tissue Specificity of the Alloimmune Response

Blood (2020) 136 (Supplement 1): 21–23.

https://doi.org/10.1182/blood-2020-141018

Published: 2020

Journal Articles

T-Cell Derived Interferon Gamma Directly Targets Intestinal Epithelium to Induce Stem Cell Apoptosis in GI Gvhd

Shuichiro Takashima, MD PhD, Maria L. Martin, PhD, Suze A. Jansen, Ya-Yuan Fu, PhD, Anastasiya Egorova, Chen Liu, MD PhD, Richard Kolesnick, MD, Caroline A. Lindemans, MD, Alan M. Hanash, MD PhD

Blood (2019) 134 (Supplement_1): 585.

https://doi.org/10.1182/blood-2019-130811

Published: 2019

Journal Articles

Graft Versus Host Disease Leads to Elimination of Tissue-Resident Innate Lymphoid Cells Following Experimental and Clinical Allogeneic Transplantation

Paola Vinci, PhD, Elena Garcia-Martinez, MD, Margaret H. O'Connor, Anastasiya Egorova, Jason Kuttiyara, Viktor Arnhold, MD, Doris M Ponce, MD, Alan M. Hanash, MD PhD

Blood (2019) 134 (Supplement_1): 3204.

https://doi.org/10.1182/blood-2019-128966

Published: 2019

Journal Articles

TP53 Mutations in AML Predict Adverse Outcome in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant

Bartlomiej M Getta, MBBS, Arnab Ghosh, MD PhD, Catherine C. Coombs, MD, Sean Devlin, PhD, Maria Arcila, MD, Abhinita Mohanty, Ross L. Levine, MD, Martin S. Tallman, MD, Ann A. Jakubowski, MD PhD, Sergio A. Giralt, MD, Alan M Hanash, MD PhD

Blood (2016) 128 (22): 3481.

https://doi.org/10.1182/blood.V128.22.3481.3481

Published: 2016

Journal Articles

Suppression of Luteinizing Hormone Enhances HSC Recovery after Hematopoietic Injuries

Enrico Velardi, PhD, Jennifer Jia-ying Tsai, PhD, Kimon V. Argyropoulos, MD, Shieh Jae-Hung, Sophie Lieberman, Fabiana Kreines, Yusuke Shono, MD PhD, Lauren Young, Tobias Wertheimer, Robert R. Jenq, MD, Alan M Hanash, MD PhD, Malcolm A.S. Moore, PhD, Marcel Van Den Brink, MD PhD, Jarrod A Dudakov, PhD

Blood (2016) 128 (22): 370.

https://doi.org/10.1182/blood.V128.22.370.370

Published: 2016

Journal Articles

Low Dose Unfractionated Heparin (UFH) Prophylaxis Is a Safe Strategy for the Prevention of Hepatic Sinusoidal Obstruction Syndrome (SOS) in Adult Allogeneic Stem Cell Transplant (HSCT) Recipients

Blood (2015) 126 (23): 4332.

https://doi.org/10.1182/blood.V126.23.4332.4332

Published: 2015

Journal Articles

RIG-I-Induced Type I IFNs Promote Regeneration of the Intestinal Stem Cell Compartment during Acute Tissue Damage

Blood (2015) 126 (23): 3072.

https://doi.org/10.1182/blood.V126.23.3072.3072

Published: 2015

Journal Articles

IL-22 Is an Intestinal Stem Cell Growth Factor, and IL-22 Administration in Vivo Reduces Morbidity and Mortality in Murine GvHD

Caroline A Lindemans, MD PhD, Anna Mertelsmann, Margaret Helen O'Connor, MS,BA, Jarrod A Dudakov, PhD, Robert Jenq, MD, Enrico Velardi, PhD, Lauren F. Young, BS, Odette M Smith, Gillian Lawrence, Natalie Luo, Juliet Ivanov, G Hua, PhD, Maria L Martin, Chen Liu, MD, PhD, Richard Kolesnick, MD, Marcel Van Den Brink, MD PhD, Alan M Hanash, MD PhD

Blood (2014) 124 (21): 651.

https://doi.org/10.1182/blood.V124.21.651.651

Published: 2014

Journal Articles

The Role of the Cytoplasmic RNA Sensor Retinoic Acid Inducible Gene- I (RIG-I) in Allogeneic Stem Cell Transplantation

Julius Clemens Fischer, MDcal student, Caroline A Lindemans, MD PhD, Chia-Ching Lin, PhD, Alexander Wintges, graduate student, Michael Bscheider, MD, Tobias Wertheimer, Simon Heidegger, MD, Robert Jenq, MD, Jarrod A Dudakov, PhD, Alan M. Hanash, MD PhD, Christian Peschel, MD, Tobias Haas, MD, Marcel R.M. van den Brink, MD PhD, Hendrik Poeck, MD

Blood (2014) 124 (21): 3827.

https://doi.org/10.1182/blood.V124.21.3827.3827

Published: 2014

Journal Articles

IL-22 Administration Decreases Intestinal Gvhd Pathology, Increases Intestinal Stem Cell Recovery, and Enhances Immune Reconstitution Following Allogeneic Hematopoietic Transplantation

Anna M Mertelsmann, Jarrod A Dudakov, PhD, Enrico Velardi, PhD, Guoqiang Hua, PhD, Fabiana M Kreines, BS, Emily R Levy, BS, Margaret O'Connor, Odette M Smith, BA, Richard Kolesnick, MD, Marcel R. M. van den Brink, MD, PhD, Alan M Hanash, MD, PhD

Blood (2013) 122 (21): 290.

https://doi.org/10.1182/blood.V122.21.290.290

Published: 2013

Journal Articles

Mutational Profiling Of Myeloid Malignancies For Prediction Of Disease Relapse Following Allogeneic Stem Cell Transplantation

Alan M Hanash, MD, PhD, Sean M. Devlin, PhD, Molly Maloy, MA, Kristina M. Knapp, BS, Vincent A. Miller, MD, Doron Lipson, PhD, Philip J. Stephens, PhD, Geoff A Otto, PhD, Roman Yelensky, PhD, Michelle K. Nahas, PhD, Kai Wang, MD PhD, Ross L. Levine, MD, Marcel R.M. van den Brink, MD, PhD, Ann A. Jakubowski, MD, PhD

Blood (2013) 122 (21): 2096.

https://doi.org/10.1182/blood.V122.21.2096.2096

Published: 2013

Journal Articles

Eomesodermin Regulates The Early Activation Of Alloreactive CD4 T Cells and Is Critical For Both Gvh and GVL Responses

Barbara Du Rocher, PhD, MSc, Odette M Smith, BA, Andrew M. Intlekofer, MD, PhD, Jarrod A Dudakov, PhD, Emily Levy, BA, Fabiana Kreiners, BA, Steven Reiner, Eliana Abdelhay, PhD , MSc, Marcel R.M. van den Brink, MD, PhD, Alan M Hanash, MD, PhD

Blood (2013) 122 (21): 133.

https://doi.org/10.1182/blood.V122.21.133.133

Published: 2013

Journal Articles

Intrathymic Innate Lymphoid Cells: Long-Lived Mediators Of Immune Regeneration

Jarrod A Dudakov, PhD, Denzel Cole, Alan M Hanash, MD, PhD, Lauren F Young, BS, Fabiana M Kreines, BS, Emily R Levy, BS, Odette M Smith, BA, Enrico Velardi, PhD, Marcel van den Brink, MD, PhD

Blood (2013) 122 (21): 289.

https://doi.org/10.1182/blood.V122.21.289.289

Published: 2013

Journal Articles

Innate Lymphoid Cell-Derived IL-22 Regulates Epithelial Recovery From Gvhd

Alan M Hanash, MD, PhD, Jarrod A Dudakov, PhD, Guoqiang Hua, PhD, Margaret O'Connor, Lauren F. Young, BS, Bruce R. Blazar, MD, Richard Kolesnick, MD, Marcel R.M. van den Brink, MD, PhD

Blood (2012) 120 (21): 339.

https://doi.org/10.1182/blood.V120.21.339.339

Published: 2012

Journal Articles

CD19-Targeted Donor T Cells Exert Potent Graft Versus Lymphoma Activity and Attenuated Gvhd

Arnab Ghosh, MD, PhD, Marco L. Davila, MD, PhD, Lauren F. Young, BS, Christopher Kloss, BS, Gertrude Gunset, BS, Odette M. Smith, BA, Mallory L. West, BS, Natalie V. Singer, BS, Amanda M. Holland, BS, Robert R. Jenq, MD, Alan M. Hanash, MD, PhD, Jarrod A. Dudakov, PhD, Enrico Velardi, PhD, Yusuke Shono, MD, PhD, Michel Sadelain, MD, PhD, Marcel R.M. van den Brink, MD, PhD

Blood (2012) 120 (21): 451.

https://doi.org/10.1182/blood.V120.21.451.451

Published: 2012

Journal Articles

Graft-Versus-Host Disease After Double-Unit Cord Blood Transplantation Has Unique Features and an Association with Engrafting Unit Recipient HLA-Match

Blood (2012) 120 (21): 4197.

https://doi.org/10.1182/blood.V120.21.4197.4197

Published: 2012

Journal Articles

Age-Related Thymic Involution Triggers Intrinsic Regeneration Pathways but They Remain Ineffective for Its Renewal

Jarrod A Dudakov, PhD, Alan M Hanash, MD, PhD, Natalie V Singer, BS, Mallory L West, BS, Lauren F. Young, BS, Robert R Jenq, MD, Richard L Boyd, PhD, Marcel Van Den Brink, MD, PhD

Blood (2012) 120 (21): 1043.

https://doi.org/10.1182/blood.V120.21.1043.1043

Published: 2012

Journal Articles

Over-Expression of TRAIL on Donor T Cells Enhances GVT and Suppresses Gvhd Via Elimination of Alloreactive T Cells and Host APC

Arnab Ghosh, MD, PhD, Yildirim Dogan, PhD, Amanda M. Holland, BS, Odette M Smith, BA, Lauren F. Young, BS, Mallory L West, BS, Natalie V Singer, BS, Robert R Jenq, MD, Il-Kang Na, MD/PhD, Olaf Penack, MD/PhD, Alan M Hanash, MD, PhD, Martin G. Sauer, MD, Michel Sadelain, MD, PhD, Marcel R.M. van den Brink, MD, PhD

Blood (2011) 118 (21): 817.

https://doi.org/10.1182/blood.V118.21.817.817

Published: 2011

Journal Articles

Innate Lymphoid Cell-Derived IL-22 Mediates Endogenous Thymic Repair Under the Control of IL-23

Jarrod A Dudakov, PhD, Alan M Hanash, MD, PhD, Lauren F. Young, BS, Natalie V Singer, BS, Mallory L West, BS, Robert R Jenq, MD, Odette M Smith, BA, Amanda M Holland, BS, Richard L Boyd, PhD, Marcel R.M. van den Brink, MD, PhD

Blood (2011) 118 (21): 143.

https://doi.org/10.1182/blood.V118.21.143.143

Published: 2011

Journal Articles

The Central Nervous System Is a Target Organ of Acute Graft-Versus-Host Disease

Steffen Hartrampf, MD, Jarrod A Dudakov, PhD, Linda K Johnson, DVM, Odette M Smith, BA, Jennifer J Tsai, MD, Alan M Hanash, MD, PhD, Natalie V Singer, BS, Mallory L West, BS, Bing F Liu, PhD, Miklos Toth, MD, PhD, Marcel R.M. van den Brink, MD, PhD

Blood (2011) 118 (21): 1895.

https://doi.org/10.1182/blood.V118.21.1895.1895

Published: 2011

NARROW

TCR Repertoires in Graft-Versus-Host-Disease (GVHD)-Target Tissues Reveals Tissue Specificity of the Alloimmune Response

T-Cell Derived Interferon Gamma Directly Targets Intestinal Epithelium to Induce Stem Cell Apoptosis in GI Gvhd

Graft Versus Host Disease Leads to Elimination of Tissue-Resident Innate Lymphoid Cells Following Experimental and Clinical Allogeneic Transplantation

TP53 Mutations in AML Predict Adverse Outcome in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant

Suppression of Luteinizing Hormone Enhances HSC Recovery after Hematopoietic Injuries

Low Dose Unfractionated Heparin (UFH) Prophylaxis Is a Safe Strategy for the Prevention of Hepatic Sinusoidal Obstruction Syndrome (SOS) in Adult Allogeneic Stem Cell Transplant (HSCT) Recipients

RIG-I-Induced Type I IFNs Promote Regeneration of the Intestinal Stem Cell Compartment during Acute Tissue Damage

IL-22 Is an Intestinal Stem Cell Growth Factor, and IL-22 Administration in Vivo Reduces Morbidity and Mortality in Murine GvHD

The Role of the Cytoplasmic RNA Sensor Retinoic Acid Inducible Gene- I (RIG-I) in Allogeneic Stem Cell Transplantation

IL-22 Administration Decreases Intestinal Gvhd Pathology, Increases Intestinal Stem Cell Recovery, and Enhances Immune Reconstitution Following Allogeneic Hematopoietic Transplantation

Mutational Profiling Of Myeloid Malignancies For Prediction Of Disease Relapse Following Allogeneic Stem Cell Transplantation

Eomesodermin Regulates The Early Activation Of Alloreactive CD4 T Cells and Is Critical For Both Gvh and GVL Responses

Intrathymic Innate Lymphoid Cells: Long-Lived Mediators Of Immune Regeneration

Innate Lymphoid Cell-Derived IL-22 Regulates Epithelial Recovery From Gvhd

CD19-Targeted Donor T Cells Exert Potent Graft Versus Lymphoma Activity and Attenuated Gvhd

Graft-Versus-Host Disease After Double-Unit Cord Blood Transplantation Has Unique Features and an Association with Engrafting Unit Recipient HLA-Match

Age-Related Thymic Involution Triggers Intrinsic Regeneration Pathways but They Remain Ineffective for Its Renewal

Over-Expression of TRAIL on Donor T Cells Enhances GVT and Suppresses Gvhd Via Elimination of Alloreactive T Cells and Host APC

Innate Lymphoid Cell-Derived IL-22 Mediates Endogenous Thymic Repair Under the Control of IL-23

The Central Nervous System Is a Target Organ of Acute Graft-Versus-Host Disease

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American Society of Hematology

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ASH Publications

American Society of Hematology

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