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Journal Articles

Platelet generation in vivo and in vitro

Jonathan Alan Furniss, Nathalie Tarassova, Alastair W Poole
Journal: Blood
Blood blood.2024024601.
https://doi.org/10.1182/blood.2024024601
Published: 2024
Journal Articles

Platelets tell old red cells to clear off

Jordan Vautrinot, Alastair W. Poole
Journal: Blood
Blood (2024) 143 (6): 480–481.
https://doi.org/10.1182/blood.2023023164
Published: 2024
Journal Articles

Thrombospondin-1 promotes hemostasis through modulation of cAMP signaling in blood platelets

Ahmed Aburima, Martin Berger, Benjamin E. J. Spurgeon, Bethany A. Webb, Katie S. Wraith, Maria Febbraio, Alastair W. Poole, Khalid M. Naseem
Journal: Blood
Blood (2021) 137 (5): 678–689.
https://doi.org/10.1182/blood.2020005382
Published: 2021
Includes: Supplemental data
Journal Articles

Platelet Membrane Procoagulation in Preeclampsia

Adrienne Lee, MD, Lorriane Chow, BSc, MD FRCPC, Leslie Skeith, MD, Joshua A Nicholas, BHSc, MD, Man-Chiu Poon, MD, Alastair W. Poole, MA, PhD VetMB, Ejaife O Agbani, PhDBPharm,MSc
Journal: Blood
Blood (2020) 136 (Supplement 1): 7.
https://doi.org/10.1182/blood-2020-137213
Published: 2020
Journal Articles

Procoagulant platelets: generation, function, and therapeutic targeting in thrombosis

Ejaife O. Agbani, Alastair W. Poole
Journal: Blood
Blood (2017) 130 (20): 2171–2179.
https://doi.org/10.1182/blood-2017-05-787259
Published: 2017
Journal Articles

Platelet dense granule secretion defects may obscure α-granule secretion mechanisms: evidence from Munc13-4–deficient platelets

Matthew T. Harper, Marion T. van den Bosch, Ingeborg Hers, Alastair W. Poole
Journal: Blood
Blood (2015) 125 (19): 3034–3036.
https://doi.org/10.1182/blood-2014-12-618439
Published: 2015
Journal Articles

Is JAK2 V617F finally off the hook?

Ingeborg Hers, Alastair W. Poole
Journal: Blood
Blood (2014) 124 (7): 992–993.
https://doi.org/10.1182/blood-2014-07-583856
Published: 2014
Journal Articles

Dysfunction of the PI3 kinase/Rap1/integrin α IIb β 3 pathway underlies ex vivo platelet hypoactivity in essential thrombocythemia

Samantha F. Moore, Roger W. Hunter, Matthew T. Harper, Joshua S. Savage, Samreen Siddiq, Sarah K. Westbury, Alastair W. Poole, Andrew D. Mumford, Ingeborg Hers
Journal: Blood
Blood (2013) 121 (7): 1209–1219.
https://doi.org/10.1182/blood-2012-05-431288
Published: 2013
Journal Articles

Bcl-x L –inhibitory BH3 mimetic ABT-737 depletes platelet calcium stores

Matthew T. Harper, Alastair W. Poole
Journal: Blood
Blood (2012) 119 (18): 4337–4338.
https://doi.org/10.1182/blood-2012-02-413070
Published: 2012
Journal Articles

Protein kinase C mediates platelet secretion and thrombus formation through protein kinase D2

Olga Konopatskaya, Sharon A. Matthews, Matthew T. Harper, Karen Gilio, Judith M. E. M. Cosemans, Christopher M. Williams, Maria N. Navarro, Deborah A. Carter, Johan W. M. Heemskerk, Michael Leitges, Doreen Cantrell, Alastair W. Poole
Journal: Blood
Blood (2011) 118 (2): 416–424.
https://doi.org/10.1182/blood-2010-10-312199
Published: 2011
Includes: Supplemental data
Journal Articles

Platelet Syk is a HIT target

Alastair W. Poole
Journal: Blood
Blood (2011) 117 (7): 2083–2084.
https://doi.org/10.1182/blood-2010-12-322248
Published: 2011
Journal Articles

Cracking the platelet WIP

Alastair W. Poole
Journal: Blood
Blood (2009) 114 (21): 4611–4612.
https://doi.org/10.1182/blood-2009-09-239905
Published: 2009
Journal Articles

PKCθ in platelet activation

Matthew T. Harper, Alastair W. Poole
Journal: Blood
Blood (2009) 114 (2): 489–491.
https://doi.org/10.1182/blood-2009-03-208454
Published: 2009
Journal Articles

PKCδ regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation

Giordano Pula, Kai Schuh, Keiko Nakayama, Keiichi I. Nakayama, Ulrich Walter, Alastair W. Poole
Journal: Blood
Blood (2006) 108 (13): 4035–4044.
https://doi.org/10.1182/blood-2006-05-023739
Published: 2006
Includes: Multimedia, Supplemental data
Journal Articles

PKCδ Regulates Platelet Activity through the Inhibition of VASP-Mediated Filopodia Formation.

Giordano Pula, PhD, Kai Schuh, PhD, Ulrich Walter, PhD, Keiichi I. Nakayama, PhD, Keiko Nakayama, PhD, Alastair W. Poole, PhD
Journal: Blood
Blood (2006) 108 (11): 1513.
https://doi.org/10.1182/blood.V108.11.1513.1513
Published: 2006
Journal Articles

Platelet-collagen interaction: a new modulator

Alastair W. Poole
Journal: Blood
Blood (2006) 107 (2): 415a–416.
https://doi.org/10.1182/blood-2005-10-4243
Published: 2006
Journal Articles

P2Y 1 and P2Y 12 receptors for ADP desensitize by distinct kinase-dependent mechanisms

Adam R. Hardy, Pamela B. Conley, Jiansong Luo, Jeffrey L. Benovic, Alastair W. Poole, Stuart J. Mundell
Journal: Blood
Blood (2005) 105 (9): 3552–3560.
https://doi.org/10.1182/blood-2004-07-2893
Published: 2005
Journal Articles

Reciprocal cross-talk between P2Y 1 and P2Y 12 receptors at the level of calcium signaling in human platelets

Adam R. Hardy, Matthew L. Jones, Stuart J. Mundell, Alastair W. Poole
Journal: Blood
Blood (2004) 104 (6): 1745–1752.
https://doi.org/10.1182/blood-2004-02-0534
Published: 2004
Journal Articles

The snake venom toxin alboaggregin-A activates glycoprotein VI

Brief Report
Naoki Asazuma, Stuart J. Marshall, Oscar Berlanga, Daniel Snell, Alastair W. Poole, Michael C. Berndt, Robert K. Andrews, Steve P. Watson
Journal: Blood
Blood (2001) 97 (12): 3989–3991.
https://doi.org/10.1182/blood.V97.12.3989
Published: 2001
Journal Articles

Glycoprotein Ib-V-IX, a Receptor for von Willebrand Factor, Couples Physically and Functionally to the Fc Receptor γ-Chain, Fyn, and Lyn to Activate Human Platelets

Shahrokh Falati, Christine E. Edmead, Alastair W. Poole
Journal: Blood
Blood (1999) 94 (5): 1648–1656.
https://doi.org/10.1182/blood.V94.5.1648
Published: 1999