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Amalia Bosia
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Journal Articles

The Mevalonate Pathway and Downstream Signal Transducers As Therapeutic Targets to Overcome Multidrug Resistance in Chronic Lymphocytic Leukemia (CLL)

Marta Coscia, MD, PhD, Micol Rigoni, PhD, Chiara Riganti, MD, Candida Vitale, MD, Ivana Campia, PhD, Valentina Griggio, PhD, Myriam Foglietta, MD, Barbara Castella, PhD, Patrizia Sciancalepore, MD, Maria Elisa Canepari, MD, Marta Robino, Daniela Drandi, PhD, Marco Ladetto, MD, Amalia Bosia, MD, Mario Boccadoro, MD, Massimo Massaia, MD
Journal: Blood
Blood (2012) 120 (21): 3881.
https://doi.org/10.1182/blood.V120.21.3881.3881
Published: 2012
Journal Articles

Dysfunctional Vγ9Vδ2 T cells are negative prognosticators and markers of dysregulated mevalonate pathway activity in chronic lymphocytic leukemia cells

Marta Coscia, Candida Vitale, Silvia Peola, Myriam Foglietta, Micol Rigoni, Valentina Griggio, Barbara Castella, Daniela Angelini, Sabina Chiaretti, Chiara Riganti, Anna Guarini, Daniela Drandi, Marco Ladetto, Amalia Bosia, Robin Foà, Luca Battistini, Mario Boccadoro, Jean-Jacques Fournié, Massimo Massaia
Journal: Blood
Blood (2012) 120 (16): 3271–3279.
https://doi.org/10.1182/blood-2012-03-417519
Published: 2012
Includes: Supplemental data
Journal Articles

The Mevalonate Pathway As a Metabolic Target to Circumvent Multidrug-Resistance in Chronic Lymphocytic Leukemia Cells

Marta Coscia, MD, PhD, Micol Rigoni, PhD, Chiara Riganti, MD, Ivana Campia, PhD, Candida Vitale, MD, Valentina Griggio, PhD, Silvia Peola, PhD, Barbara Castella, PhD, Patrizia Sciancalepore, MD, Daniela Drandi, PhD, Marco Ladetto, MD, Amalia Bosia, MD, Mario Boccadoro, MD, Massimo Massaia, MD
Journal: Blood
Blood (2011) 118 (21): 735.
https://doi.org/10.1182/blood.V118.21.735.735
Published: 2011
Journal Articles

The Defective Proliferation of Vgamma9Vdelta2 T Cells to Zoledronic Acid In Chronic Lymphocytic Leukemia (CLL) Is a Powerful Time to First Treatment (TFT) Predictor Associated with the IGHV Mutational Status

Marta Coscia, MD, PhD, Candida Vitale, MD, Silvia Peola, PhD, Chiara Riganti, MD, Daniela Angelini, PhD, Myriam Foglietta, MD, Francesca Pantaleoni, PhD, Giorgia Matta, MD, Sabina Chiaretti, MD, Anna Guarini, PhD, Daniela Drandi, PhD, Marco Ladetto, MD, Amalia Bosia, MD, Luca Battistini, MD, Robin Foà, MD, Mario Boccadoro, MD, Jean-Jacques Fournié, PhD, Massimo Massaia, MD
Journal: Blood
Blood (2010) 116 (21): 3602.
https://doi.org/10.1182/blood.V116.21.3602.3602
Published: 2010
Journal Articles

IGHV Unmutated Chronic Lymphocytic Leukemia (CLL) B Cells Are More Susceptible to Spontaneous Apoptosis Than Mutated CLL B Cells and Are Subject to the Anti-Apoptotic Effect of Environmental Signals

Marta Coscia, MD, PhD, Francesca Pantaleoni, PhD, Chiara Riganti, MD, Candida Vitale, MD, Micol Rigoni, PhD, Silvia Peola, PhD, Daniela Drandi, PhD, Barbara Castella, PhD, Marina Ruggeri, PhD, Paola Omedè, MD, Marco Ladetto, MD, Amalia Bosia, MD, Mario Boccadoro, MD, Massimo Massaia, MD
Journal: Blood
Blood (2010) 116 (21): 2431.
https://doi.org/10.1182/blood.V116.21.2431.2431
Published: 2010
Journal Articles

Differential Effects of Microenvironmental Elements On Tumor Cells Survival in Chronic Lymphocytic Leukemia Patient Subsets with Good or Poor Prognosis.

Marta Coscia, MD, Francesca Pantaleoni, PhD, Chiara Riganti, MD, Micol Rigoni, PhD, Candida Vitale, MD, Silvia Peola, PhD, Daniela Drandi, Marco Ladetto, Amalia Bosia, MD, Mario Boccadoro, Massimo Massaia, MD
Journal: Blood
Blood (2009) 114 (22): 2333.
https://doi.org/10.1182/blood.V114.22.2333.2333
Published: 2009
Journal Articles

The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL

Francesco E. Boccalatte, Claudia Voena, Chiara Riganti, Amalia Bosia, Lucia D'Amico, Ludovica Riera, Mangeng Cheng, Bruce Ruggeri, Ole N. Jensen, Valerie L. Goss, Kimberly Lee, Julie Nardone, John Rush, Roberto D. Polakiewicz, Michael J. Comb, Roberto Chiarle, Giorgio Inghirami
Journal: Blood
Blood (2009) 113 (12): 2776–2790.
https://doi.org/10.1182/blood-2008-06-161018
Published: 2009
Includes: Supplemental data
Journal Articles

Phenotypic and Functional Features of Vγ9/Vδ2 T Cells in Chronic Lymphocytic Leukemia Are Strongly Correlated with the Mutational Status of the Immunoglobulin Heavy Chain Variable Region (IgVH) and Metabolic Activity of the Mevalonate Pathway in Tumor Cells.

Marta Coscia, MD, Silvia Peola, PhD, Giorgia Matta, MD, Francesca Pantaleoni, PhD, Myriam Foglietta, MD, Daniela Angelini, PhD, Sabina Chiaretti, MD, Chiara Riganti, MD, Anna Guarini, PhD, Daniela Drandi, PhD, Marco Ladetto, MD, Amalia Bosia, MD, Robin Foà, MD, Luca Battistini, MD, Mario Boccadoro, MD, Jean Jacques Fournie, PhD, Massimo Massaia, MD
Journal: Blood
Blood (2007) 110 (11): 1131.
https://doi.org/10.1182/blood.V110.11.1131.1131
Published: 2007