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Journal Articles

Longitudinal analysis of MRD negativity and immune dynamics in patients with transplant-ineligible newly diagnosed multiple myeloma treated with iberdomide, daratumumab, and dexamethasone from the CC-220-MM-001 trial

Free
Danny Jeyaraju, Sanhita Sengupta, Paulo Maciag, Anna Sureda Balarí, Niels W.C.J. van de Donk, Sagar Lonial, Anita Gandhi, Michael Amatangelo
Journal: Blood
Blood (2025) 146 (Supplement 1): 2255.
https://doi.org/10.1182/blood-2025-2255
Published: 2025
Journal Articles

Mezigdomide overcomes CRBN mutations emerging post IMiD therapy

Free
Edmond Watson, Chad Bjorklund, Nicholas Stong, Scott Hollingsworth, Olivia Pierce, Yilin Meng, Veerabahu Shanmugasundaram, Ting-Hsiang Huang, Vinidhra Sridharan, Tracy Chow, Michael Amatangelo, Patrick Hagner, Anita Gandhi
Journal: Blood
Blood (2025) 146 (Supplement 1): 436.
https://doi.org/10.1182/blood-2025-436
Published: 2025
Journal Articles

EZH2 inhibition synergizes with aiolos/ikaros degradation via coordinated chromatin remodeling and FoxO activation in multiple myeloma

Free
Ting-Hsiang Huang, Chih-Chao Hsu, Junfei Zhao, Patrick Hagner, Anita Gandhi
Journal: Blood
Blood (2025) 146 (Supplement 1): 5699.
https://doi.org/10.1182/blood-2025-5699
Published: 2025
Journal Articles

Pharmacodynamic activity and clinical benefits of mezigdomide in high-risk biomarker subgroups from the CC-92480-MM-001 study

Free
Tracy Chow, Nicholas Stong, Keyur Desai, Saleh Tamim, Chad Bjorklund, Joseph Hadala, Cynthia Donahue, Phillip Koo, Erica Petrlik, Jessica Katz, Anita Gandhi, Suzanne Trudel, Nizar Bahlis, Paul Richardson, Michael Amatangelo
Journal: Blood
Blood (2025) 146 (Supplement 1): 5697.
https://doi.org/10.1182/blood-2025-5697
Published: 2025
Journal Articles

Shared immune features correspond to high-risk multiple myeloma across multiple human subtypes and murine models

Free
Junia Vieira, Fnu Nabuqi, Alison Park, Alessia D'Anna, Tarek Mouhieddine, Kiana Chen, Erik Guillen, Roshan Mathews, Gregoire Lauvau, Jing Zhang, Katerina Kappes, Rudra Prasad Dutta, Julie Fortier, Chad Bjorklund, Michael Amatangelo, Anita Gandhi, Zhihong Chen, Seunghee Kim-Schulze, Michael Slade, Udo Oppermann, Rena Feinman, Santiago Thibaud, Joshua Richter, Shambavi Richard, Cesar Rodriguez Valdes, Adriana Rossi, Hearn Cho, Fotios Asimakopoulos, David Siegel, Ravi Vij, Sundar Jagannath, Samir Parekh, David Fooksman, Alessandro Lagana
Journal: Blood
Blood (2025) 146 (Supplement 1): 5723.
https://doi.org/10.1182/blood-2025-5723
Published: 2025
Journal Articles

Predictive biomarkers of luspatercept and erythropoiesis-stimulating agent (ESA) hematological response and overall survival (OS) in patients with lower-risk myelodysplastic syndromes (LR-MDS) in the commands trial

Free
Guillermo Garcia-Manero, Manuel Ugidos, Maroof Hasan, Matthew Stokes, Matteo Della Porta, Amer Zeidan, Valeria Santini, Uwe Platzbecker, Rami Komrokji, Dimana Miteva, Veronika Pozharskaya, Anita Gandhi, Daniel Lopes de Menezes, Rajasekhar Suragani
Journal: Blood
Blood (2025) 146 (Supplement 1): 5613.
https://doi.org/10.1182/blood-2025-5613
Published: 2025
Journal Articles

IQGAP1 is a novel non-degraded substrate of CELMoDs and involved in trafficking of immune cells to the tumor microenvironment

Free
Hsiling Chiu, Ari Salinger, Pei Hsuan Chen, Andy Christoforou, Antonia Lopez-Girona, Ashok Dongre, Anita Gandhi, Patrick Hagner
Journal: Blood
Blood (2025) 146 (Supplement 1): 5340.
https://doi.org/10.1182/blood-2025-5340
Published: 2025
Journal Articles

Luspatercept reduces cardiac stress and improves cardiac function in a TET2-deficient mouse model with features of heart failure with preserved ejection fraction: Evidence from phase 3 commands trial and pre-clinical studies

Free
Manuel Ugidos, Sarita Nehra, Manoj Dokania, Gobinathan Rengarasu, Guillermo Garcia-Manero, Uwe Platzbecker, Anita Gandhi, Ching-Pin Chang, Ricardo Garcia, Jyoti Gulia, Rajasekhar Suragani, Maroof Hasan
Journal: Blood
Blood (2025) 146 (Supplement 1): 233.
https://doi.org/10.1182/blood-2025-233
Published: 2025